scholarly journals Phytochemical and Biological Evaluation of a Newly Designed Nutraceutical Self-Nanoemulsifying Self-Nanosuspension for Protection and Treatment of Cisplatin Induced Testicular Toxicity in Male Rats

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 408
Author(s):  
Sherif R. Abdel-All ◽  
Zeinab T. Abdel Shakour ◽  
Dalia M. N. Abouhussein ◽  
Enji Reda ◽  
Thoraya F. Sallam ◽  
...  
Keyword(s):  
Antineoplastic Agent ◽  
Biological Evaluation ◽  
Particle Size Analysis ◽  
Male Rats ◽  
Size Analysis ◽  
Dilution Method ◽  
Tribulus Terrestris ◽  
Testicular Toxicity ◽  
Transmission Electron ◽  
Male Wistar Rats

The incorporation of cisplatin (CP) as a cytotoxic antineoplastic agent in most chemotherapeutic protocols is a challenge due to its toxic effect on testicular tissues. Natural compounds present a promising trend in research, so a new nutraceutical formulation (NCF) was designed to diminish CP spermatotoxicity. A combination of three nutraceutical materials, 250 mg Spirulina platensis powder (SP), 25 mg Tribulus terrestris L. extract (TT), and 100 mg fish oil (FO) were formulated in self-nanoemulsifying self-nanosuspension (SNESNS). SP was loaded into the optimized self-nanoemulsifying system (30% FO, 50% span 80/cremophor EL and 20% isopropanol) and mixed with TT aqueous solution to form SNESNS. For the SP, phytochemical profiling revealed the presence of valuable amounts of fatty acids (FAs), amino acids, flavonoids, polyphenols, vitamins, and minerals. Transmission electron microscopy (TEM) and particle size analysis confirmed the formation of nanoemulsion-based nanosuspension upon dilution. Method validation of the phytochemical constituents in NCF has been developed. Furthermore, NCF was biologically evaluated on male Wistar rats and revealed the improvement of spermatozoa, histopathological features, and biochemical markers over the CP and each ingredient group. Our findings suggest the potential of NCF with SNESNS as a delivery system against CP-induced testicular toxicity in male rats.

scholarly journals Green Synthesized Silver Nanoparticles Immobilized on Activated Carbon Nanoparticles: Antibacterial Activity Enhancement Study and Its Application on Textiles Fabrics

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3790
Author(s):  
Pratama Jujur Wibawa ◽  
Muhammad Nur ◽  
Mukhammad Asy’ari ◽  
Wijanarka Wijanarka ◽  
Heru Susanto ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Activated Carbon ◽  
Aloe Vera ◽  
Particle Size Analysis ◽  
Size Analysis ◽  
E Coli ◽  
Transmission Electron ◽  
Average Size ◽  
Green Synthesized Silver Nanoparticles

This research aimed to enhance the antibacterial activity of silver nanoparticles (AgNPs) synthesized from silver nitrate (AgNO3) using aloe vera extract. It was performed by means of incorporating AgNPs on an activated carbon nanoparticle (ACNPs) under ultrasonic agitation (40 kHz, 2 × 50 watt) for 30 min in an aqueous colloidal medium. The successful AgNPs synthesis was clarified with both Ultraviolet-Visible (UV-Vis) and Fourier Transform Infrared (FTIR) spectrophotometers. The successful AgNPs–ACNPs incorporation and its particle size analysis was performed using Transmission Electron Microscope (TEM). The brown color suspension generation and UV-Vis’s spectra maximum wavelength at around 480 nm confirmed the existence of AgNPs. The particle sizes of the produced AgNPs were about 5 to 10 nm in the majority number, which collectively surrounded the aloe vera extract secondary metabolites formed core-shell like nanostructure of 8.20 ± 2.05 nm in average size, while ACNPs themselves were about 20.10 ± 1.52 nm in average size formed particles cluster, and 48.00 ± 8.37 nm in average size as stacking of other particles. The antibacterial activity of the synthesized AgNPs and AgNPs-immobilized ACNPs was 57.58% and 63.64%, respectively (for E. coli); 61.25%, and 93.49%, respectively (for S. aureus). In addition, when the AgNPs-immobilized ACNPs material was coated on the cotton and polyester fabrics, the antibacterial activity of the materials changed, becoming 19.23% (cotton; E. coli), 31.73% (polyester; E. coli), 13.36% (cotton; S. aureus), 21.15% (polyester; S. aureus).

Preparation of Amorphous Nanosilica from Philippine Waste Rice Hull via Acid Precipitation Method

2016 ◽  
Vol 864 ◽  
pp. 112-116
Author(s):  
Rinlee Butch M. Cervera ◽  
Emie A. Salamangkit-Mirasol
Keyword(s):  
Electron Microscopy ◽  
Low Cost ◽  
Agricultural Waste ◽  
Acid Precipitation ◽  
Particle Size Analysis ◽  
Precipitation Method ◽  
Rice Hull ◽  
Size Analysis ◽  
Rice Hull Ash ◽  
Transmission Electron

Rice hull or rice husk (RH) is an agricultural waste obtained from milling rice grains. Since RH has no commercial value and is difficult to use in agriculture, its volume is often reduced through open field burning which is an environmental hazard. In this study, amorphous nanosilica from Philippine waste RH was prepared via acid precipitation method. The synthesized samples were fully characterized for its microstructural properties. X-ray diffraction pattern reveals that the structure of the prepared sample is amorphous in nature while Fourier transform infrared spectrum showed the different vibration bands of the synthesized sample. Scanning electron microscopy (SEM) and particle size analysis (PSA) confirmed the presence of agglomerated silica particles. On the other hand, transmission electron microscopy (TEM) revealed an amorphous sample with grain sizes of about 5 to 20 nanometer range and has about 95 % purity according to EDS analyses. The elemental mapping also suggests that leaching of rice hull ash effectively removed the metallic impurity such as potassium element in the material. Hence, amorphous nanosilica was successfully prepared via a low-cost acid precipitation method from Philippine waste rice hull.

The Evaporative Decomposition of Solutions Method (Eds) for the Production of Ultrafine Y1Ba2Cu3O7 from Nitrate and Mixed Anion Precursor Solutions

1989 ◽  
Vol 169 ◽  
Author(s):  
Rollin E. Lakis ◽  
Sidney R. Butler
Keyword(s):  
Electron Microscopy ◽  
Particle Size ◽  
Barium Carbonate ◽  
Hollow Spheres ◽  
Particle Size Analysis ◽  
Size Analysis ◽  
Gravimetric Analysis ◽  
X Ray Diffraction ◽  
X Ray ◽  
Transmission Electron

AbstractY1Ba2Cu3O7 has been prepared by the evaporative decomposition of solutions method. Nitrate and mixed anion solutions were atomized and decomposed at temperatures ranging from 300°C to 950°C. The resulting materials have been characterized using x-ray powder diffraction, Thermal Gravimetric Analysis (TGA), particle size analysis, Scanning Electron Microscopy (SEM), and Transmission Electron Microscopy (TEM). The powder consists of 0.3 micron agglomerated hollow spheres with a primary particle size of 0.06 micron. TGA and x-ray diffraction indicate the presence of barium nitrate and barium carbonate due to incomplete decomposition and/or product contamination by the process environment.

Particle Size Analysis of the Synthesized Al2O3 by Dissolution and Alkali Fusion-Coprecipitation Methods

2020 ◽  
Vol 860 ◽  
pp. 128-134
Author(s):  
Cahyaning Fajar Kresna Murti ◽  
Malik Anjelh Baqiya ◽  
Endarko ◽  
Triwikantoro
Keyword(s):  
Particle Size ◽  
Ammonium Hydroxide ◽  
Particle Size Analysis ◽  
Fusion Product ◽  
Size Analysis ◽  
Particle Sizes ◽  
X Ray Diffraction ◽  
Bottom Up ◽  
Alkali Fusion ◽  
Transmission Electron

Particle size analysis of synthesized Al2O3 by dissolution and alkali fusion-coprecipitation methods has been conducted. The formation of nano- or microparticles can be synthesized by the top-down (physically) and bottom-up (chemically) methods. In this study, the commercial alumina (Merck) with the particle size of 63 µm was synthesized through the bottom-up method. The dissolution method was done by reacting to alumina with ammonium hydroxide (NH4OH). The alkali fusion method was carried out by reacting alumina with sodium hydroxide (NaOH) and it obtained by coprecipitation of the alkali fusion product with HCl and NH4OH. The result from both methods were calcined at 600°C. The phase of synthesized Al2O3 was identified by using X-ray diffraction (XRD), whereas the morphology observed using a transmission electron microscope (TEM), and the particle sizes measured by particle sizes analyzer (PSA). The XRD pattern shows the γ-Al2O3 phases with particle sizes of ~33 nm and ~25 nm from TEM observations, while the PSA results revealed agglomerated particles with particle sizes of 1263 nm and 477 nm for the dissolution and alkali fusion-coprecipitation method, respectively. Therefore, both methods can be used to reduce the particle size of γ-Al2O3.

Study on the Reaction Process of Ploy-High-Ferric-Silicic Coagulant

2010 ◽  
Vol 156-157 ◽  
pp. 1074-1077
Author(s):  
Yan Zhen Yu ◽  
Juan Tan ◽  
Yong Sun
Keyword(s):  
Particle Size ◽  
Electron Microscope ◽  
Theoretical Basis ◽  
Raw Materials ◽  
Particle Size Analysis ◽  
Synthesis Process ◽  
Size Analysis ◽  
Potassium Ferrate ◽  
Transmission Electron ◽  
Complexation Process

A new inorganic polymer coagulant，ploy-high-ferric-silicic coagulant with various Si/FeO42- ratios and salt-basicity, was prepared using the fly ash extract and potassium ferrate. The influence of both Si/FeO42- ratios and salt-basicity on the complexation process was explored with many analytical methods, such as transmission electron microscope (TEM), lased particle size analysis (LPSA) and infrared spectrum (IR). The results show that the ploy-high-ferric-silicic is a complexation compound, instead of a simple mixture of raw materials. The complexation process between Si and Fe may be different from various Si/FeO42- ratios and salt-basicity. The bonding can help revealing the high-ferric groups function in synthesis process. From analyzing the different ferrosilicon bonding modes, it can provide some theoretical basis to compound high-ferric coagulant.

Solvothermal synthesis of zirconia and yttria-stabilized zirconia nanocrystalline particles

2007 ◽  
Vol 22 (1) ◽  
pp. 46-55 ◽  
Author(s):  
Xin M. Wang ◽  
Ping Xiao
Keyword(s):  
Electron Microscopy ◽  
Nitrogen Adsorption ◽  
Particle Size Analysis ◽  
Zirconium Hydroxide ◽  
Yttria Stabilized Zirconia ◽  
Size Analysis ◽  
Stabilized Zirconia ◽  
Particle Properties ◽  
Transmission Electron ◽  
Nanocrystalline Particles

A solvothermal method was used to prepare zirconia and yttria-stabilized zirconia (YSZ) particles using zirconium hydroxide and yttrium hydroxide particles as precursors and ethanol or isopropanol as reaction media. The particle properties were characterized with x-ray diffractometry, scanning electron microscopy, transmission electron microscopy, thermal analysis, laser particle-size analysis, nitrogen adsorption (Brunauer–Emmett–Teller method) and Zeta potential analysis. Cubic/tetragonal ZrO2 and YSZ nanocrystals with crystallite size around 5 nm were obtained. The effect of different hydroxide precursors, attrition milling of hydroxide precursors, solvothermal processing conditions, and mineralizer was investigated and discussed by referring to the crystallization process of zirconium hydroxides.

Synthesis and characterization of nanoparticles of Ba2EuZrO5.5: A new complex perovskite ceramic oxide

2000 ◽  
Vol 15 (10) ◽  
pp. 2125-2130 ◽  
Author(s):  
R. Jose ◽  
J. James ◽  
Asha M. John ◽  
R. Divakar ◽  
J. Koshy
Keyword(s):  
High Resolution ◽  
Electron Diffraction ◽  
Particle Size Analysis ◽  
Electron Microscopic Investigation ◽  
Perovskite Oxide ◽  
Size Analysis ◽  
Complex Perovskite ◽  
Electron Microscopic ◽  
X Ray ◽  
Transmission Electron

Nanoparticles of barium europium zirconate, a complex perovskite oxide, were synthesized using a modified self-propagating combustion synthesis. The solid combustion products thus obtained were characterized by x-ray and electron diffraction, differential thermal analysis, thermogravimetric analysis, infrared spectroscopy, particle-size analysis, surface area determination, gas adsorption studies, and high-resolution transmission electron microscopy. According to the results of the x-ray and electron diffraction, as-prepared powder showed the single phase of barium europium zirconate (Ba2EuZrO5.5) without another phase and had a complex cubic perovskite (A2BB′O6) structure. The transmission electron microscopic investigation showed a mean grain size of 38 nm with a standard deviation of 12 nm. High-resolution lattice imaging of the nanoparticles indicated the possibility of finer crystallite in the particle having the same orientation. The nanoparticles of Ba2EuZrO5.5 obtained by the present method could be sintered to 97% theoretical density at a relatively low temperature of 1525 °C.

scholarly journals Ultrasound-Assisted Transglutaminase Catalysis of the Cross-Linking and Microstructure of αs-Casein, β-Casein and κ-Casein

Processes ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1630
Author(s):  
Chun-Chi Chen ◽  
Liang-Yu Chen ◽  
Wen-Tai Li ◽  
Ken-Lin Chang ◽  
Hsien-Wei Tseng ◽  
...  
Keyword(s):  
Particle Size Analysis ◽  
Size Analysis ◽  
Cross Linking ◽  
Comprehensive Utilization ◽  
Transmission Electron ◽  
Microscopy Investigation ◽  
Electron Microscopy Investigation ◽  
Sds Page ◽  
The Cross ◽  
The Individual

The effects of ultrasonic treatment (UT)-assisted transglutaminase (TGase) catalysis on the physicochemical properties of individual αs-casein (αs-CN), β-casein (β-CN), and κ-casein (κ-CN) were investigated. After 60 min of incubation at 30 °C, αs-CN, β-CN, and κ-CN were cross-linked with TGase (6.0 units/mL), and high molecular weight polymers (>200 kDa) were formed. The use of TGase in conjunction with UT (20 kHz, power of 400 W, and amplitude 20%) led to an increase in the rate of αs-CN, β-CN, and κ-CN polymerization compared to the individual casein that contained TGase but did not undergo UT. SDS-PAGE scrutiny showed that the intensities of αs-CN, β-CN, and κ-CN incubation with regard to TGase and UT at 30 °C for 60 min noticeably decreased to 5.66 ± 0.39, 3.97 ± 0.43, and 26.07 ± 1.18%, respectively (p < 0.05). Particle size analysis results indicated that the molecule size appropriation for the cross-linking of αs-CN, β-CN, and κ-CN ranged from 6000 to 10,000 nm after 60 min incubation with TGase and UT. Transmission electron microscopy investigation showed network structures of cross-linking αs-CN, β-CN, and κ-CN were formed from αs-CN, β-CN, and κ-CN, respectively. As our results show, the comprehensive utilization of TGase and UT will be a superior method for the polymerization of αs-CN, β-CN, and κ-CN.

Synthesis and Characterization of Polyimide/Silica Nanocomposites

2011 ◽  
Vol 311-313 ◽  
pp. 96-100
Author(s):  
Jian Li Cheng ◽  
Cun Zhou ◽  
Hao Peng ◽  
Huan Wang ◽  
Yu Sun
Keyword(s):  
Particle Size ◽  
Average Particle Size ◽  
Amic Acid ◽  
Particle Size Analysis ◽  
Size Analysis ◽  
Average Particle ◽  
Scanning Calorimetry ◽  
Silica Nanocomposites ◽  
Transmission Electron ◽  
Size Of Particles

Two kind of polyimide/silica nanocomposites which were recorded poly(amic acid)/ silica(PAA/SiO2) and SiO2in poly(amic acid) ammonium salt(PAS/SiO2) respectively, have been prepared for different methods. The size of SiO2in PAA/SiO2and PAS/SiO2are measured by Particle size analysis and the average particle size are 377nm and 53.7nm. Transmission electron microscopy(TEM) images of PAS/ SiO2confirm that the size of particles are ranged from 40 to 80nm. The stuctures of samples have been characterized by FT-IR spectra. The thermal stability of PAA/SiO2and PAS/SiO2are studied by thermogravimetric analysis (TGA) and the thermal behaviors were investigated by differential scanning calorimetry (DSC) in this paper. It is shown that PAA/SiO2have slightly better thermal properties than that of PAS/SiO2. The results obtained from Instron universal strength tester present the water-solube PAS/SiO2own the excellent mechanical prperties as same as PAA/SiO2.

Preparation, Characterization of Co3O4 Nano-Particles and its Catalytic Effect on the Combustion of Fuel Rich Propellants

2012 ◽  
Vol 560-561 ◽  
pp. 284-288 ◽  
Author(s):  
Wei Qiang Pang ◽  
Xiao Bing Shi ◽  
Yang Li
Keyword(s):  
Particle Size ◽  
Catalytic Effect ◽  
Solid Phase ◽  
Particle Size Analysis ◽  
Nano Particles ◽  
Size Analysis ◽  
X Ray Diffraction ◽  
Transmission Electron ◽  
Wide Size Distribution

The mono-dispersed Co3O4 nano-particles were prepared by means of solid phase synthetical method. The particle size, specific surface area, crystal structure and morphology of the samples were characterized by laser particle size analysis, x-ray diffraction (XRD) and transmission electron microscopy (TEM), respectively. The catalytic effects of nano-particles on the combustion of fuel rich propellant were investigated. The results show that the Co3O4 nano-particles prepared are uniform and with relatively wide size distribution curve. The catalytic effect of Co3O4 nano-particles on the fuel rich propellant is stronger than those of micro-sized Co3O4 particles and CuO nano-particles.

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