scholarly journals Artificial Intelligence Assisted Ultrasonic Extraction of Total Flavonoids from Rosa sterilis

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3835
Author(s):  
Jing Liu ◽  
Chaochan Li ◽  
Guijie Ding ◽  
Wenxuan Quan
Keyword(s):  
Artificial Intelligence ◽  
Ethanol Concentration ◽  
Antioxidant Activities ◽  
Ultrasonic Method ◽  
Extraction Process ◽  
Total Flavonoids ◽  
Liquid Ratio ◽  
Ga Algorithm ◽  
Kinetics Of ◽  
Extraction Power

Flavonoids in Rosa sterilis were studied. The flavonoids in Rosa sterilis were extracted by ultrasonic method, and the extraction conditions were modeled and optimized by response the surface methodology and the artificial intelligence method. The results show that the ultrasonic method can effectively extract total flavonoids, and the extraction rate is close to the prediction value of ANN-GA algorithm, which proves the rationality of the model. The order of the effects of the parameters on the experiment was material liquid ratio > extraction power > extraction time > ethanol concentration. In addition, the scavenging effects of flavonoids on DPPH, O2−· and ·OH were also determined, and these indicated that flavonoids have strong antioxidant activities. The kinetics of the extraction process was studied by using the data of the extraction process, and it was found that the extraction process conformed to Fick’s first law.

Study on Extraction of Total Flavonoids from Licorice with Ultrasonic Assistance and Antioxidant Activity

2012 ◽  
Vol 550-553 ◽  
pp. 1629-1632 ◽  
Author(s):  
Yu Hong Zou ◽  
Qiu Xia Han ◽  
Lin Guo
Keyword(s):  
Antioxidant Activity ◽  
Ethanol Concentration ◽  
Extraction Process ◽  
Free Radical Scavenger ◽  
Extraction Rate ◽  
Radical Scavenger ◽  
Total Flavonoids ◽  
Ultrasonic Power ◽  
Liquid Ratio ◽  
Solid Liquid

To optimize the extraction process of total flavonoids from RADIX RHIZOMA GLYCYRRHIZAE and Study on the Antioxidant Activity. Total flavonoids were extracted from RADIX RHIZOMA GLYCYRRHIZAE with ethanol by ultrasonic-assisted method, whose extraction process was optimized by orthogonal test design.The scavenging effect of pumpkin polysaccharide on OH and O2-were studied by salicylic acid and pyrogallic acid method. The optimum extraction process was as follows: ethanol concentration of 75%, solid-liquid ratio of 1:25,ultrasonic power of 350 W and ultrasonic duration of 25 min.Under the above conditions, the extraction rate of total flavonoids reached as high as 1.943%. The influencing order of each factor on extraction rate of polysaccharides was determined to be: ethanol concentration＞solid-liquid ratio＞ultrasonic power＞ultrasonic duration. When the solution concentration is 1.1296mg/ml, the scavenging rate of crude flavonoids on superoxide radical is 50%.Suggesting that it would be an effctive natural free radical scavenger. The study could provide a scientific basis for the further exploitation and utilization of RADIX RHIZOMA GLYCYRRHIZAE

Optimum Process for Extraction of Total Flavonoids from Castor Leaves by Orthogonal Test

2014 ◽  
Vol 989-994 ◽  
pp. 1029-1032
Author(s):  
Yi Hua Jiang ◽  
Xin Long Jiang ◽  
Cheng Gang Cai
Keyword(s):  
Ethanol Concentration ◽  
Orthogonal Test ◽  
Optimum Process ◽  
Total Flavonoids ◽  
Extraction Temperature ◽  
Optimal Conditions ◽  
Liquid Ratio ◽  
Test Methodology ◽  
Maximal Yield ◽  
Solid Liquid

Optimization of total flavonoid extraction from Castor leaves using orthogonal test methodology with the factors of ethanol concentration, extraction temperature,extraction time,solid/liquid ratio on the yield of total flavonoids were investigated.The results showed that optimum extracting conditions of total flavonoids from castor leaves were as follows: adding 1:40 g·mL-1 of 30% alcohol and extracting for 30 min,extraction temperature 70°C. Under the optimal conditions, the maximal yield of flavonoids was of 1.81%.

Extraction of Polysaccharides from Pumpkin by Ultrasonic Method and it’s Primary Antioxidant Activities Research

2011 ◽  
Vol 183-185 ◽  
pp. 1970-1974
Author(s):  
Jie Sun ◽  
Guo You Yin ◽  
Hua Zhang ◽  
Lan Ying Chen ◽  
Chang Zheng Hu
Keyword(s):  
Antioxidant Activities ◽  
Ultrasonic Method ◽  
Dependent Manner ◽  
Ultrasonic Power ◽  
Liquid Ratio ◽  
Optimum Parameters ◽  
Ultrasonic Time ◽  
Total Antioxidant ◽  
Primary Antioxidant ◽  
Solid Liquid

In this study, effects of ultrasound processing time, ultrasound power and solid liquid ratio of ultrasonic on pumpkin polysaccharide extraction were investigated. The optimum parameters of extracting pumpkin polysaccharides are obtained by orthogonal test. Antioxidant activity were evaluated by using various established invitro systems, including 1,1-diphenyl-2-picrylhydrazylthe(DPPH•), hydroxyl(•OH) and FRAP system. Results showed that the extraction rate of polysaccharides pumpkin could up to 12.37% which the condition were water as extractant, ultrasonic time is 10min, ultrasonic power is 400w, solid to liquid ratio is 1:20. The polysaccharide raised the total antioxidant capacity in a dose-dependent manner. The results suggested that polysaccharide had direct and potent antioxidant activities.

Extraction Technology and Determination of Total Flavonoid in Magnolia Liliiflora Petals

2014 ◽  
Vol 941-944 ◽  
pp. 1003-1007 ◽  
Author(s):  
Yi Hua Jiang ◽  
Xin Long Jiang ◽  
Cheng Gang Cai
Keyword(s):  
Ethanol Concentration ◽  
Orthogonal Experiment ◽  
Total Flavonoids ◽  
Liquid Ratio ◽  
Extraction Technology ◽  
Assisted Extraction ◽  
Irradiation Power ◽  
Maximal Yield ◽  
Solid Liquid

Orthogonal experiment optimization of microwave-assisted extraction (MAE) conditions of total flavonoids from Magnolia liliflora petals with the factors of ethanol concentration, extraction time,microwave power,solid/liquid ratio on the yield of total flavonoids were studied. The results showed that optimum extracting conditions of total flavonoids from Magnolia liliflora were as follows: adding 1:10 g·mL-1 of 40% alcohol and extracting for 5 min,microwave irradiation power 464W, under the optimal conditions, the maximal yield of flavonoids was of 2.08%.

scholarly journals Optimization Of Microwave-Assisted Extraction Of Flavonoids From Binahong (Anredera cordifolia) Leaves Using Respon Surface Methodology

2020 ◽  
Vol 7 (3) ◽  
pp. 10-19
Author(s):  
Zaldy Rusli ◽  
Bina Lohita Sari ◽  
Novi Fajar Utami ◽  
S Sabila
Keyword(s):  
Antioxidant Activity ◽  
Ethanol Concentration ◽  
Antioxidant Activities ◽  
Extraction Process ◽  
Extraction Time ◽  
Microwave Assisted Extraction ◽  
Optimum Conditions ◽  
Microwave Assisted ◽  
Assisted Extraction

Binahong (Anredera scandens (L.) Moq.) leaves are one of the plants that empirically can be used for wound healing and contain flavonoids which have antibacterial and antioxidant activities. Determination of the optimum conditions of the Binahong leaf extraction process needs to be done to ensure the extraction quality of the Binahong leaves associated with the given activity. Microwave Assisted Extraction (MAE) is an extraction that utilizes microwave radiation to heat the solvent quickly and efficiently. This study aims to determine the most effective binahong leaf extraction conditions that produce optimal levels of flavonoids and antioxidant activity. The extraction process was carried out using the Microwave assisted extraction (MAE) method. Determination of optimum conditions is done based on Response Surface Method (RSM) with variable ethanol concentration (70%, 80% and 90%), extraction time (4, 12 and 20 minutes) and power (450, 600, and 800 watts) using Box- Behnken Design (BBD) with Design Expert 7.0 software. The extract quality parameters measured were total flavonoid levels and antioxidant activity. The results showed the optimum conditions with the BBD method were obtained at an ethanol concentration of 81.49%, extraction time of 13.84 minutes, and power of 626.19 watts with flavonoid levels of 3.8561% and antioxidant activity (IC50) of 95.51834 ppm with active categories.

STUDYING THE KINETIC CHARACTERISTICS OF THE EXTRACTION OF ANTHOCYANINS FROM THE SQUEEZE OF KRASNOSTOP ZOLOTOVSKY

2020 ◽  
Author(s):  
M.A. Egyan ◽  
Keyword(s):  
Reaction Rate ◽  
Sugar Content ◽  
Extraction Process ◽  
Efficiency Coefficient ◽  
Kinetic Characteristics ◽  
Reaction Rate Constants ◽  
Solids Content ◽  
Kinetics Of ◽  
Process Speed

The article shows studies characterizing the quality of the squeeze: the mechanical composition of the squeeze is determined, the structural moisture of each component is determined, the sugar content in the formed process of sedimentation of the juice and its acidity are determined refractometrically. The kinetics of anthocyanins extraction was determined in two ways, the solids content in the extract was calculated, and the reaction rate constants of the extraction process and the efficiency coefficient of ultrasonic amplification of the extraction process speed were calculated.

Phytochemical Screening, Antimicrobial and Antioxidant Activities of Selected Mangrove Species

2020 ◽  
Vol 16 (2) ◽  
pp. 152-163 ◽  
Author(s):  
Nilesh L. Dahibhate ◽  
Utpal Roy ◽  
Kundan Kumar
Keyword(s):  
Staphylococcus Epidermidis ◽  
Methanol Extract ◽  
Ethyl Acetate Extract ◽  
Antioxidant Activities ◽  
Avicennia Marina ◽  
Total Flavonoids ◽  
Phytochemical Screening ◽  
Mangrove Species ◽  
Sonneratia Caseolaris ◽  
Bruguiera Gymnorhiza

Background: Mangrove plant extracts are used in folkloric medicine as aphrodisiac, sedative, antioxidant, antimicrobial and antimalarial. Screening for antimicrobial, phytochemical and antioxidant activities of fourteen mangroves plant species (Aegiceras corniculatum, Acanthus ilicifolius, Avicennia alba, Avicennia marina, Avicennia officinalis, Bruguiera cylindrica, Bruguiera gymnorhiza, Ceriops tagel, Excoecaria agallocha, Kandelia candel, Rhizophora apiculata, Rhizophora mucronata, Sonneratia alba, and Sonneratia caseolaris) in various solvents are reported in this work. Methods: The antimicrobial screening was carried out using agar well diffusion method. In this study, nine pathogenic strains were used, including three Gram-positive and six Gram-negative bacteria. Phytochemical screening, total flavonoids, total phenolic and antioxidant activity was tested by DPPH radical scavenging assay. Four phenolic compounds (gallic acid, vanillin, tannic acid and quercetin) were quantified by LC-MS/MS in selected mangrove species. Results: Antimicrobial screening showed Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Pseudomonas aeruginosa were most susceptible to ethyl acetate extract as compared to ethanol and methanol extract. Ethyl acetate extract of Avicennia marina and Bruguiera gymnorhiza showed strong antibacterial activity against Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Pseudomonas aeruginosa. Phytochemical analysis revealed the presence of saponins, phenolics, flavonoids, alkaloids, tannins, and terpenoids, which was found to be variable as per the solvent used for extraction. In addition, total phenolics and total flavonoids content with different solvents were found in the range of 11.08 to 196.76 mg GAE/g and 12.92 to 110.3 mg QE/g of extract respectively. Moreover, antioxidant capacities expressed in terms of IC50 (mg/mL) showed that methanol extract exhibited higher antioxidant capacity followed by ethanol extract. LC-MS/MS analysis showed gallic acid and tannic acid are present in higher concentration in Aegiceras corniculatum and Sonneratia caseolaris than other species. The vanillin and quercetin were found in the least concentration. Conclusion: Mangroves species are rich source of antioxidant, phenolics and antimicrobial compounds.

scholarly journals Optimization of banana crop by-products solvent extraction for the production of bioactive compounds

2021 ◽  
Author(s):  
Sara Díaz ◽  
Antonio N. Benítez ◽  
Sara Ramírez-Bolaños ◽  
Lidia Robaina ◽  
Zaida Ortega
Keyword(s):  
Antioxidant Activity ◽  
Aqueous Ethanol ◽  
Ethanol Concentration ◽  
Extraction Process ◽  
Total Phenol Content ◽  
Optimal Conditions ◽  
Satisfactory Description ◽  
Optimized Conditions ◽  
By Products ◽  
Banana Crops

AbstractThe aim of this work is the optimization of phenolic compound extraction from three by-products of banana crops (rachis, discarded banana, and banana’s pseudostem pulp), as a way to valorize them through a green extraction process. The influence of the temperature and aqueous ethanol concentration (Et-OH) on extract properties (total phenol content (TPC) and antioxidant activity) was firstly analyzed. 78 ℃ and ethanol concentrations close to 50% yielded the best results for the three materials. The equations obtained by the response surface methodology gave a satisfactory description of the experimental data, allowing optimizing the extraction conditions. Under optimized conditions, time influence was then assessed, although this parameter seemed not influence results. Among the three by-products, rachis extract (60% Et-OH, 78 ℃, and 30 min) presented the highest TPC (796 mg gallic acid/100 g of dried material) and antioxidant activity (6.51 mg Trolox equivalents/g of dried material), followed by discarded banana, and pseudostem pulp. Under the optimal conditions, experiments were performed at a larger scale, allowing to determine the extraction yields (EY) and to characterize the extracts. The highest EY was obtained for the rachis (26%), but the extract with the highest activity was obtained for discarded banana (50% Et-OH, 78 ℃, and 60 min), which presented a TPC of 27.26 mg/g extract corresponding to 54.59 mg Trolox equivalents/g extract. This study contributes to the valorization of banana crops residues as a source of polyphenolic compounds with bioactive functions that can be extracted under economic extraction conditions. Graphical abstract

Optimization and characterization of flavonoids extracted from Cannabis sativa fibers

2021 ◽  
pp. 004051752110277
Author(s):  
Qilu Cui ◽  
Jiawei Li ◽  
Chongwen Yu
Keyword(s):  
Chemical Structure ◽  
Cannabis Sativa ◽  
Ethanol Concentration ◽  
Extraction Process ◽  
Test Results ◽  
Hemp Fiber ◽  
Hemp Fibers ◽  
Structure Surface ◽  
Degumming Process

In this paper, the extraction process of flavonoids from hemp fibers was studied. Response surface methodology (RSM) analysis of the extraction parameters indicated that optimized results would be ethanol concentration 76 vol.%, bath ratio 1:50, and reaction time 139 min; therefore, an optimal extraction rate of flavonoids of 0.2275% can be obtained. The chemical structure, surface morphology and element composition of flavonoid extracts were analyzed. The test results indicated that hemp extract contains flavonoids, which can be used to extract flavonoids from hemp fiber, so as to comprehensively develop hemp fiber and reduce the discharge of waste liquid in the traditional degumming process.

scholarly journals Optimization of Betalain Pigments Extraction Using Beetroot by-Products as a Valuable Source

Inventions ◽  
2021 ◽  
Vol 6 (3) ◽  
pp. 50
Author(s):  
Silvia Lazăr (Mistrianu) ◽  
Oana Emilia Constantin ◽  
Nicoleta Stănciuc ◽  
Iuliana Aprodu ◽  
Constantin Croitoru ◽  
...  
Keyword(s):  
Citric Acid ◽  
Acid Concentration ◽  
Ethanol Concentration ◽  
Extraction Process ◽  
Extraction Time ◽  
Quadratic Model ◽  
Citric Acid Concentration ◽  
Operating Variables ◽  
Conventional Solvent Extraction ◽  
Optimized Conditions

(1) Background: This study is designed to extract the bioactive compounds from beetroot peel for future use in the food industry. (2) Methods: Spectrophotometry techniques analyzed the effect of conventional solvent extraction on betalains and polyphenolic compounds from beetroot peels. Several treatments by varying for factors (ethanol and citric acid concentration, temperature, and time) were applied to the beetroot peel samples. A Central Composite Design (CCD) has been used to investigate the effect of the extraction parameters on the extraction steps and optimize the betalains and total polyphenols extraction from beetroot. A quadratic model was suggested for all the parameters analyzed and used. (3) Results: The maximum and minimum variables investigated in the experimental plan in the coded form are citric acid concentration (0.10–1.5%), ethanol concentration (10–50%), operating temperature (20–60 °C), and extraction time (15–50 min). The experimental design revealed variation in betalain content ranging from 0.29 to 1.44 mg/g DW, and the yield of polyphenolic varied from 1.64 to 2.74 mg/g DW. The optimized conditions for the maximum recovery of betalains and phenols were citric acid concentration 1.5%, ethanol concentration 50%, temperature 52.52 °C, and extraction time 49.9 min. (4) Conclusions: Overall, it can be noted that the extraction process can be improved by adjusting operating variables in order to maximize the model responses.

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