scholarly journals Impact of Nutritional Status on Gastroenteropancreatic Neuroendocrine Tumors (GEP-NET) Aggressiveness

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1854 ◽  
Author(s):  
Luigi Barrea ◽  
Barbara Altieri ◽  
Giovanna Muscogiuri ◽  
Daniela Laudisio ◽  
Giuseppe Annunziata ◽  
...  

Neuroendocrine tumors (NETs) are rare neoplasms mostly originating from the gastroenteropancreatic tract (GEP-NETs). Data regarding nutritional status in GEP-NET patients are limited. The aim of the study was to investigate the nutritional status and adherence to the Mediterranean Diet (MD) in GEP-NET patients and to correlate them with tumor aggressiveness. A cross-sectional case-control observational study was conducted enrolling 83 patients with well-differentiated G1/G2 GEP-NETs after resection, as well as 83 healthy subjects, age, sex and body mass index-matched. Nutritional status was assessed by evaluating with Bioelectrical Impedance analysis and its phase angle (PhA), adherence to the MD according to PREDIMED score, dietary assessment, anthropometric parameters, and clinico-pathological characteristics. GEP-NET patients consumed less frequently vegetables, fruits, wine, fish/seafood, nuts, and more frequently red/processed meats, butter, cream, margarine, and soda drinks than controls. Patients with more aggressive disease presented a lower adherence to MD according to PREDIMED categories in comparison to G1, localized and free/stable disease status. A smaller PhA value and a lower PREDIMED score were significantly correlated with G2 tumor, metastases, and progressive disease. To the best of our knowledge, this is the first study reporting an association between nutritional status and tumor aggressiveness in a selected group of GEP-NETs. Moreover, higher intakes of food of MD, may represent a potential tool for prevention of tumor aggressiveness. Thus, a skilled nutritionist should be an integral part of the multidisciplinary management of GEP-NET patients.

2018 ◽  
Vol 9 (1) ◽  
pp. 24-30
Author(s):  
Mirele S. Mialich ◽  
Bruna R. Silva ◽  
Alceu A. Jordao

Abstract The objective of this study was to improve the cutoff points of the traditional classification of nutritional status and overweight / obesity based on the BMI in a Brazilian sample. A cross-sectional study was conducted on 1301 individuals of both genders aged 18 to 60 years. The subjects underwent measurement of weight and height and bioelectrical impedance analysis. Simple linear regression was used for statistical analysis, with the level of significance set at p < 0.05. The sample consisted of 29.7% men and 70.3% women aged on averaged 35.7 ± 17.6 years; mean weight was 67.6 ± 16.0 kg, mean height was 164.9 ± 9.5 cm, and mean BMI was 24.9 ± 5.5 kg/m2. As expected, lower cutoffs were found for BMI than the classic reference points traditionally adopted by the WHO for the classification of obesity, i.e., 27.15 and 27.02 kg/m2 for obesity for men and women, respectively. Other authors also follow this tendency, Romero-Corral et al. (2008) suggested 25.8 to 25.5 kg/m2 for American men and women as new values for BMI classification of obesity. Gupta and Kapoor (2012) proposed 22.9 and 28.8 kg/m2 for men and women of North India. The present investigation supports other literature studies which converge in reducing the BMI cutoff points for the classification of obesity. Thus, we emphasize the need to conduct similar studies for the purpose of defining these new in populations of different ethnicities.


2018 ◽  
Vol 12 (2) ◽  
pp. 191
Author(s):  
Anisaul Makarimah ◽  
Lailatul Muniroh

Menarche is first menstruation that an indicator of teenage girlsenter puberty phase. Nowadays the age of menarche has decreasedin tothe younger. The purpose of this study was to analyze the relation between nutritional status and body fat percentage with menarche age. This research used cross sectional design with sample size of 37 female students who had experienced menstruation and selected using simple random sampling. Data were collected by anthropometric measurements to assess nutritional status, body fat percentage using Bioelectrical Impedance Analysis (BIA). Data were analyzed by Spearman correlation test. The results showed that more than half of respondents had normal nutritional status (51.4%) and healthy body fat percentage. There was a correlation between nutritional status (p=0.029, r= -0.360) and body fat percentage (p =0.048, r=-0.328) with age of menarche among teenage girls at the Muhammadiyah GKB 1 Gresik Elementary School. The conclusion of this study was higher nutritional status (score of z-score) and fat percentage will decrease the age of menarche. Research suggestion is to normalize nutritional status and percent body fat. By maintaining consumption pattern and increase physical activity, such as cycling, swimming, and others.


2021 ◽  
Vol 10 (2) ◽  
pp. 319
Author(s):  
Arnati Wulansari ◽  
Kasyani Kasyani

 The role of nutrition in the life cycle is very important. If there is a problem with malnutrition, this is a sign that you are at risk of suffering from chronic disease. Measurement of nutritional status and body fat percentage is important as an initial screening to prevent the risk of chronic disease. This study aims to describe the performance of the nutritional status and body fat percentage of new student STIKes Baiturrahim 2020. This study used a cross-sectional study. The research was conducted at STIKes Baiturrahim Jambi in September 2019. The number of respondents was 148 people. The data used are the characteristics of the respondents (age, sex, body weight, and height) and the percent of body fat obtained from measurement of Bioelectrical Impedance Analysis (BIA). The results showed that most of them had normal nutritional status (64,2%) and body fat percentage was classified as normal (41,9%). It is recommended that students maintain normal nutritional status and body fat percentage and also always monitoring the body weight to prevent chronic disease


Author(s):  
J. Willers ◽  
A. Hahn ◽  
T. Köbe ◽  
S. Gellert ◽  
V. Witte ◽  
...  

In this cross-sectional study, body composition of fifty-eight mild cognitive impairment (MCI) patients (single and multiple domain) and fifty healthy older control subjects by the use of bioelectrical impedance analysis (BIA) was assessed. Measurements were: height, weight, body mass index, BIA: phase angle (PA), total body water (TBW), lean body mass (LBM), body cell mass (BCM), extracellular mass (ECM), body fat mass (BFM), apolipoprotein E4, and physical activity level. Compared to BIA reference values and healthy subjects, MCI patients had significant differences in PA (only female), BCM and ECM/BCM index. Differences were more pronounced in females compared to males. The low levels of BCM and PA suggest that MCI patients, especially of female sex, have a poor nutritional status. BIA-derived PA might be a suitable indicator, that could enhance evaluation of nutritional status in patients with cognitive decline.


Author(s):  
Andi Masnilawati ◽  
Nia Karuniawati

Based on nutritional status, women who are obese have a higher risk of menstrual cycle disorder compared to women with normal nutrient status. The purpose of the study was to promote the difference in the prevalence of menstrual patterns based on nutritional status in teenagers in midwifery school, Universitas Muslim Indonesia. This research used cross-sectional design. Samples in this study were 56 people. The data were collected by filling questionnaires and direct measurements of nutritional status based on the per cent of body fat using a Bioelectrical Impedance Analysis (BIA) method, then analysed using Chi-Square. The results of this study showed 56 young women who had an average body fat per cent of 29 (51.8%). As the results, it indicated a significant relationship between the per cent of body fat with the long disorders period of menstruation (p = 0.01). Whereas the per cent of body fat with menstrual cycles did not show the prominent relationship (p = 0.33) as well as between per cent body fat with painful menstruation which there is no significant relationship (p = 0.24). Besides, the situation can be caused by several factors such as changes in hormone and stress. Keywords: menstruation disorder; body fat; teenagers ABSTRAK Berdasarkan status gizi, wanita yang mengalami obesitas memiliki risiko gangguan siklus menstruasi lebih tinggi dibandingkan dengan wanita dengan status gizi normal. Tujuan penelitian adalah memgetahui perbedaan prevalensi gangguan pola menstruasi, berdasarkan status gizi pada remaja di program D-III Kebidanan UMI. Desain penelitian ini adalah cross sectional. Sampel penelitian ini adalah 56 orang. Data dikumpulkan melalui pengisian kuesioner dan pengukuran langsung status gizi berdasarkan persen lemak tubuh menggunakan metode Bioelectrical Impedance Analysis (BIA). Data dianalisis menggunakan uji Chi square. Hasil penelitian ini menunjukkan bahwa dari 56 remaja putri yang memiliki persen lemak tubuh normal sebanyak 29 (51,8%). Terdapat hubungan yang signifikan antara persen lemak tubuh dengan gangguan lama menstruasi (p=0,01), sedangkan antara persen lemak tubuh dengan siklus menstruasi tidak ada hubungan signifikan (p=0,33) begitupun juga dengan antara persen lemak tubuh dengan nyeri haid tidak ada hubungan yang signifikan (p=0,24) hal ini bisa disebabkan oleh beberapa faktor antar lain perubahan hormon dan stress. Kata kunci: gangguan mentruasi; lemak tubuh; remaja


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yusuke Hori ◽  
Masatoshi Hoshino ◽  
Kazuhide Inage ◽  
Masayuki Miyagi ◽  
Shinji Takahashi ◽  
...  

AbstractWe investigated the relationship between trunk muscle mass and spinal pathologies by gender. This multicenter cross-sectional study included patients aged ≥ 30 years who visited a spinal outpatient clinic. Trunk and appendicular muscle mass were measured using bioelectrical impedance analysis. The Oswestry Disability Index (ODI), visual analog scale (VAS) score for low back pain, sagittal vertical axis (SVA), and EuroQol 5 Dimension (EQ5D) score were investigated to evaluate spinal pathology. The association between trunk muscle mass and these parameters was analyzed by gender using a non-linear regression model adjusted for patients’ demographics. We investigated the association between age and trunk muscle mass. We included 781 men and 957 women. Trunk muscle mass differed significantly between men and women, although it decreased with age after age 70 in both genders. Lower trunk muscle mass was significantly associated with ODI, SVA, and EQ5D score deterioration in both genders; its association with VAS was significant only in men. Most parameters deteriorated when trunk muscle mass was < 26 kg in men and < 19 kg in women. Lower trunk muscle mass was associated with lumbar disability, spinal imbalance, and poor quality of life in both genders, with significant difference in muscle mass.


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