scholarly journals Human Milk Omega-3 Fatty Acid Composition Is Associated with Infant Temperament

Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2964 ◽  
Author(s):  
Jennifer Hahn-Holbrook ◽  
Adi Fish ◽  
Laura M. Glynn
Keyword(s):  
Fatty Acids ◽  
Human Milk ◽  
Infant Temperament ◽  
Gas Liquid Chromatography ◽  
Infant Behavior ◽  
Linear Regression Models ◽  
Omega 3 ◽  
Pufa Composition ◽  
Total Fat ◽  
Infant Birth

There is growing evidence that omega-3 (n-3) polyunsaturated fatty-acids (PUFAs) are important for the brain development in childhood and are necessary for an optimal health in adults. However, there have been no studies examining how the n-3 PUFA composition of human milk influences infant behavior or temperament. To fill this knowledge gap, 52 breastfeeding mothers provided milk samples at 3 months postpartum and completed the Infant Behavior Questionnaire (IBQ-R), a widely used parent-report measure of infant temperament. Milk was assessed for n-3 PUFAs and omega-6 (n-6) PUFAs using gas-liquid chromatography. The total fat and the ratio of n-6/n-3 fatty acids in milk were also examined. Linear regression models revealed that infants whose mothers’ milk was richer in n-3 PUFAs had lower scores on the negative affectivity domain of the IBQ-R, a component of temperament associated with a risk for internalizing disorders later in life. These associations remained statistically significant after considering covariates, including maternal age, marital status, and infant birth weight. The n-6 PUFAs, n-6/n-3 ratio, and total fat of milk were not associated with infant temperament. These results suggest that mothers may have the ability to shape the behavior of their offspring by adjusting the n-3 PUFA composition of their milk.

scholarly journals A novel FADS2 isoform identified in human milk fat globule suppresses FADS2 mediated Δ6-desaturation of omega-3 fatty acids

2018 ◽  
Vol 138 ◽  
pp. 52-59 ◽  
Author(s):  
Kumar S.D. Kothapalli ◽  
Hui Gyu Park ◽  
Xiaoxian Guo ◽  
Xuepeng Sun ◽  
James Zou ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Human Milk ◽  
Milk Fat ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Human Milk Fat

scholarly journals Human Milk Composition and Dietary Intakes of Breastfeeding Women of Different Ethnicity from the Manawatu-Wanganui Region of New Zealand

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1231 ◽  
Author(s):  
Christine Butts ◽  
Duncan Hedderley ◽  
Thanuja Herath ◽  
Gunaranjan Paturi ◽  
Sarah Glyn-Jones ◽  
...  
Keyword(s):  
Fatty Acids ◽  
New Zealand ◽  
Breast Milk ◽  
Human Milk ◽  
Milk Composition ◽  
Pacific Island ◽  
Dietary Intakes ◽  
Omega 3 ◽  
Food Diary ◽  
Milk Samples

Human milk is nutrient rich, complex in its composition, and is key to a baby’s health through its role in nutrition, gastrointestinal tract and immune development. Seventy-eight mothers (19–42 years of age) of Asian, Māori, Pacific Island, or of European ethnicity living in Manawatu-Wanganui, New Zealand (NZ) completed the study. The women provided three breast milk samples over a one-week period (6–8 weeks postpartum), completed a three-day food diary and provided information regarding their pregnancy and lactation experiences. The breast milk samples were analyzed for protein, fat, fatty acid profile, ash, selected minerals (calcium, magnesium, selenium, zinc), and carbohydrates. Breast milk nutrient profiles showed no significant differences between the mothers of different ethnicities in their macronutrient (protein, fat, carbohydrate, and moisture) content. The breast milk of Asian mothers contained significantly higher levels of polyunsaturated fatty acids (PUFAs), omega-3 (n-3) and omega-6 (n-6) fatty acids, docosahexaenoic acid (DHA), and linoleic acids. Arachidonic acid was significantly lower in the breast milk of Māori and Pacific Island women. Dietary intakes of protein, total energy, saturated and polyunsaturated fat, calcium, phosphorus, zinc, iodine, vitamin A equivalents, and folate differed between the ethnic groups, as well as the number of serves of dairy foods, chicken, and legumes. No strong correlations between dietary nutrients and breast milk components were found.

scholarly journals PENGARUH PADAT TEBAR TERHADAP KANDUNGAN ZAT GIZI IKAN LELE YANG DIPELIHARA DENGAN TEKNOLOGI BIOFLOK

2019 ◽  
Vol 20 (2) ◽  
pp. 120-131
Author(s):  
Settings Anang Suhardianto ◽  
Ariyanti Hartari
Keyword(s):  
Fatty Acids ◽  
Confidence Interval ◽  
Water Content ◽  
Unsaturated Fatty Acids ◽  
Statistical Tests ◽  
Stocking Density ◽  
Nutrient Content ◽  
Omega 3 ◽  
Omega 6 ◽  
Total Fat

This study aims to determine the effect of stocking density on the nutrient content of catfish that is maintained with biofloc technology. Nutrients observed: 1) water content, 2) protein, 3) carbohydrates, 4) total fat, 5) saturated fatty acids / SFA, 6) monounsaturated fatty acids/ MUFA, 7) plural unsaturated fatty acids / PUFA , 8) omega-3, 9) omega-6, and 10) omega 9. Statistical tests on the 10 variables showed that stocking density did not have a significant effect on the 10 variables at a 5% confidence interval. Stocking density of treatment is 1000 heads/pond (T1), 2000 heads/pond (T2), 3000 heads/pond (T3), with a pond size of 2.0 m x height 1.0 m. Research results: 1. The average water content is 69.40–71.47% and the highest T3. 2. The protein content is 14.70-15.90%, the highest T2. 3. Carbohydrate content of 5.16-5.50%, the highest T2. 4. The average total fat content of 6.73-7.78%, the highest T1. 5. SFA content is around 43%, PUFA around 23%, and MUFA around 32%. 6. The highest omega-3 content is T3, then T1, and T2. Omega-6 and 9 sequence contents are T1, T2, and T3. It was concluded, the treatment of biofloc catfish stocking densities at a 5% confidence interval did not have a significant effect on the specified nutrient content. Penelitian ini bertujuan untuk menentukan pengaruh padat tebar terhadap kandungan zat gizi ikan lele yang dipelihara dengan teknologi bioflok. Zat gizi yang diamati: 1) kandungan air, 2) protein, 3) karbohidrat, 4) lemak total, 5) asam lemak jenuh/SFA, 6) asam lemak tak jenuh tunggal/MUFA, 7) asam lemak tak jenuh jamak/PUFA, 8) omega-3, 9) omega 6, dan 10) omega 9. Uji statistik terhadap ke-10 variabel menunjukkan padat tebar tidak memberikan pengaruh nyata terhadap ke-10 variabel pada selang kepercayaan 5%.  Padat tebar perlakuan adalah 1000 ekor/kolam (T1),  2000 ekor/kolam (T2), 3000 ekor/kolam (T3), dengan ukuran kolam diameter 2,0 m x tinggi 1,0 m. Hasil penelitian: 1. Rata-rata kandungan air 69,40–71,47% dan T3 tertinggi. 2. Kandungan protein 14,70–15,90%, T2 tertinggi. 3. Kandungan karbohidrat 5,16–5,50%, T2 tertinggi. 4. Rata-rata kandungan lemak total 6,73–7,98%, T1 tertinggi. 5. Kandungan SFA sekitar 43%, PUFA sekitar 23%, dan MUFA sekitar 32%. 6. Kandungan omega-3 tertinggi T3, kemudian T1, dan T2. Omega-6 dan 9 urutan kandungannya T1, T2, dan T3.  Disimpulkan, perlakuan padat tebar lele bioflok pada selang kepercayaan 5% tidak memberikan pengaruh yang nyata terhadap kandungan zat gizi yang ditentukan.

Human Milk Fat Substitutes Containing Omega-3 Fatty Acids

2006 ◽  
Vol 54 (10) ◽  
pp. 3717-3722 ◽  
Author(s):  
Neşe Şahín ◽  
Casimir C. Akoh ◽  
Artemi̇s Karaalí
Keyword(s):  
Fatty Acids ◽  
Human Milk ◽  
Milk Fat ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Human Milk Fat Substitutes ◽  
Fat Substitutes ◽  
Human Milk Fat

scholarly journals Cardiovascular and Renal Calcification and Bone: A comparison of the effect of Dietary Fatty Acids

2015 ◽  
Vol 1 (3) ◽  
pp. 127 ◽  
Author(s):  
Rachell Nicoll
Keyword(s):  
Risk Factors ◽  
Fatty Acids ◽  
Fish Oil ◽  
Dietary Fatty Acids ◽  
Arterial Calcification ◽  
Ectopic Calcification ◽  
Omega 3 ◽  
Total Fat ◽  
Cv Disease ◽  
Intima Medial Thickness

Cardiovascular (CV) and renal calcification is regularly found with osteoporosis and both are conditions of chronic<br />inflammation and oxidative stress. Intake of dietary fatty acids is known to impact on the incidence of CV disease and bone<br />loss but few studies have specifically looked at their impact on CV or renal calcification. This review found that although a<br />very high total fat intake is likely to prove detrimental to both tissues and bone, particularly with low calcium intake, human<br />studies often show mixed results, possibly because fatty acid intake shows a U-shaped dose/response curve, contrary to the<br />expected linear relationship. Nevertheless, intake of fish and fish oil are generally found to protect against ectopic calcification<br />and bone loss, with a low omega 6 to omega 3 ratio (preferably &lt;5:1) proving critical. Fish intake of 3-4 servings a week was<br />believed to be optimal. In arteries, the relationship between fish oil intake and other markers of sub-clinical atherosclerosis,<br />such as intima-medial thickness, may be stronger than their relationship with arterial calcification. Any association with arterial<br />calcification often lost significance after adjustment for CV risk factors, suggesting that fish oil may act principally by lowering<br />risk factors and calling into question whether CV calcification is a condition of dyslipidaemia.

scholarly journals Nutritional Enhancement of Health Beneficial Omega-3 Long-Chain Polyunsaturated Fatty Acids in the Muscle, Liver, Kidney, and Heart of Tattykeel Australian White MARGRA Lambs Fed Pellets Fortified with Omega-3 Oil in a Feedlot System

Biology ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 912
Author(s):  
Shedrach Benjamin Pewan ◽  
John Roger Otto ◽  
Robert Tumwesigye Kinobe ◽  
Oyelola Abdulwasiu Adegboye ◽  
Aduli Enoch Othniel Malau-Aduli
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Human Health ◽  
Chain Polyunsaturated Fatty Acid ◽  
Fatty Acid Profiles ◽  
Omega 3 ◽  
Pufa Composition ◽  
Nutritional Enhancement ◽  
Long Chain

The aim of this research was to evaluate the nutritional enhancement of omega-3 long-chain polyunsaturated fatty acid (n-3 LC-PUFA) composition of edible lamb Longissimus thoracis et lumborum muscle, heart, kidney, and liver in response to dietary supplementation of lot-fed lambs with or without omega-3 oil fortified pellets. The hypothesis tested was that fortifying feedlot pellets with omega-3 oil will enhance the human health beneficial n-3 LC-PUFA composition of edible lamb muscle tissue and organs. Seventy-five Tattykeel Australian White lambs exclusive to the MARGRA brand, with an average body weight of 30 kg at six months of age, were randomly assigned to the following three dietary treatments of 25 lambs each, and lot-fed as a cohort for 47 days in a completely randomized experimental design: (1) Control grain pellets without oil plus hay; (2) Omega-3 oil fortified grain pellets plus hay; and (3) Commercial whole grain pellets plus hay. All lambs had ad libitum access to the basal hay diet and water. Post-slaughter fatty acid composition of the Longissimus thoracis et lumborum muscle, liver, kidney, and heart were determined using thee gas chromatography–mass spectrophotometry technique. Results indicated significant variations (p < 0.05) in fatty acid profiles between tissues and organs. Omega-3 oil fortified pellets significantly (p < 0.05) increased ≥C20 n-3 LC-PUFA (C20:5n-3 eicosapentaenoate, EPA + C22:5n3 docosapentaenoate, DPA + C22:6n3 docosahexanoate DHA); C18:3n-3 alpha-linolenate, ALA; C18:2 conjugated linoleic acid, CLA; total monounsaturated fatty acids, MUFA; polyunsaturated fatty acids, PUFA contents; and reduced the ratio of omega-6 to omega-3 fatty acids in all lamb organs and tissues without impacting shelf-life. The findings demonstrate that the inclusion of omega-3 oil in feedlot diets of lambs enhances the human health beneficial omega-3 long-chain polyunsaturated fatty acid profiles of edible muscle tissue and organs without compromising meat quality.

scholarly journals Polyunsaturated fatty acid concentrations in human hindmilk are stable throughout 12-months of lactation and provide a sustained intake to the infant during exclusive breastfeeding: an Italian study

2000 ◽  
Vol 84 (1) ◽  
pp. 103-109 ◽  
Author(s):  
Franca Marangoni ◽  
Carlo Agostoni ◽  
Anna M. Lammard ◽  
Marcello Giovannini ◽  
Claudio Galli ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Human Milk ◽  
Acid Composition ◽  
Saturated Fatty Acids ◽  
Total Fat ◽  
Extended Lactation ◽  
Long Chain

While a wealth of data on the fatty acid composition of mature human milk has been published, limited information is available on the quantities of individual fatty acids supplied to the suckling infant with maternal milk, through the whole first year of life. Our aim was to qualitatively and quantitatively evaluate the fatty acid composition of human milk from Italian mothers, throughout extended lactation with particular emphasis on the long-chain polyunsaturated fatty acids. We have thus measured the total fat content and the concentrations of major fatty acids by quantitative GLC in pooled breast hindmilk collected from all feedings over 24 h at colostrum, 1, 3, 6, 9 and 12 months in ten mothers recruited after delivery of full-term infants. Total saturated fatty acids progressively increase and total monounsaturated progressively decrease as percentage levels, while among long-chain polyunsaturated fatty acids, percentages of arachidonic acid and docosahexaenoic acid decrease from colostrum up to the third month. Hindmilk total lipids (mg/dl) rise more than twofold up to 3 months, and then remain stable. The amounts (mg/dl) of linoleic acid and α-linolenic acid progressively increase, following the trend of total fat, while arachidonic and docosahexaenoic concentrations (mg/dl) remain stable throughout the whole nursing period. Assessment of the intakes per kg body weight shows different trends for the individual major long-chain polyunsaturated fatty acids supplied to the infant from hindmilk during exclusive breast-feeding (3 months). This information may be useful for the evaluation of infant intakes during extended lactation.

scholarly journals Diet, Secondhand Smoke, and Glycated Hemoglobin (HbA1c) Levels among Singapore Chinese Adults

2019 ◽  
Vol 16 (24) ◽  
pp. 5148
Author(s):  
Brianna F. Moore ◽  
Lesley M. Butler ◽  
Annette M. Bachand ◽  
Agus Salim ◽  
Stephen J. Reynolds ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Secondhand Smoke ◽  
Health Study ◽  
Linear Regression Models ◽  
Omega 3 ◽  
Product Term ◽  
Singapore Chinese ◽  
The Individual ◽  
Hba1c Levels

The combination of poor diet and exposure to secondhand smoke may increase hemoglobin A1c (HbA1c) levels, but few studies have explored this interaction. We explored an interaction among 574 never-smoking adults from the Singapore Chinese Health Study. At baseline (age 59 ± 8 years), intakes of omega-3 polyunsaturated fatty acids, vitamin C, vitamin E and fiber were estimated using a modified food frequency questionnaire. At follow-up (age 64 ± 9 years), HbA1c and cotinine were measured. A product term between cotinine (above or below the median value) and each nutrient (high or low intake) was included in separate linear regression models with HbA1c as the outcome. HbA1c among those with high cotinine and low omega-3 polyunsaturated fatty acids intakes were higher than would be expected due to the individual effects alone (p-for-interaction = 0.05). Among those with lower intakes of omega-3 polyunsaturated fatty acids, high cotinine levels were associated with 0.54% higher HbA1c levels (95% confidence interval [CI]: 0.02, 1.06). Conversely, among those with higher intakes of omega-3 polyunsaturated fatty acids, HbA1c differ not differ by exposure (−0.09%; 95% CI: −0.45, 0.30). No evidence of interaction was observed for other nutrients. Diets high in omega-3 polyunsaturated fatty acids may ameliorate secondhand smoke-induced increases in HbA1c.

scholarly journals Comparison of Human Milk Fatty Acid Composition of Women From Cambodia and Australia

2018 ◽  
Vol 34 (3) ◽  
pp. 585-591 ◽  
Author(s):  
Chang Gao ◽  
Ge Liu ◽  
Kyly C. Whitfield ◽  
Hou Kroeun ◽  
Timothy J. Green ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Human Milk ◽  
Acid Composition ◽  
Milk Fatty Acid ◽  
Omega 3 ◽  
Milk Samples ◽  
Total Fat ◽  
Chloroform Methanol ◽  
Two Populations

Background: Human milk is a rich source of omega-3 long-chain polyunsaturated fatty acids, which are postulated to be important for brain development. There is a lack of data on the human milk fatty acid composition of Cambodian women compared with data from Western women. Research Aim: The aim of this study was to determine the human milk fatty acid composition of women living in Cambodia and compare it with that of women living in Australia. Method: Human milk samples from Cambodian ( n = 67) and Australian ( n = 200) mothers were collected at 3 to 4 months postpartum. Fatty acid composition was analyzed using capillary gas chromatography followed by Folch extraction with chloroform/methanol (2:1 v/v), and fat content was measured gravimetrically. Result: Compared with Australian participants, human milk from Cambodian participants contained a significantly lower level of total fat (2.90 vs. 3.45 g/dL, p = .028), lower percentages of linoleic acid (9.30% vs. 10.66%, p < .0001) and α-linolenic acid (0.42% vs. 0.95%, p < .0001), but higher percentages of arachidonic acid (0.68% vs. 0.38%, p < .0001) and docosahexaenoic acid (0.40% vs. 0.23%, p < .0001). Conclusion: Differences in human milk fatty acid composition between Cambodian and Australian participants may be explained by differences in the dietary patterns between the two populations.

Sign in / Sign up

Export Citation Format

Share Document