scholarly journals Dietary Patterns in Relation to Prospective Sleep Duration and Timing among Mexico City Adolescents

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2305 ◽  
Author(s):  
Erica C. Jansen ◽  
Ana Baylin ◽  
Alejandra Cantoral ◽  
Martha María Téllez Rojo ◽  
Helen J. Burgess ◽  
...  
Keyword(s):  
Sleep Duration ◽  
Dietary Patterns ◽  
A Posteriori ◽  
Diet Patterns ◽  
Sleep Timing ◽  
Social Jetlag ◽  
Timing Difference ◽  
Wrist Actigraphy ◽  
Prior Analysis

Adult studies show that healthy diet patterns relate to better sleep. However, evidence during adolescence, when sleep may change dramatically, is lacking. Within a cohort of 458 Mexican adolescents, we examined whether consumption of three dietary patterns was associated with sleep duration and timing measured 2 years later, as well as changes in sleep timing and duration. Dietary patterns (identified a posteriori in a prior analysis) were assessed with a baseline food frequency questionnaire, and sleep was measured with wrist actigraphy at baseline and follow-up. Linear regression analyses adjusting for sex, age, screen time, and smoking were conducted. Adolescents with higher consumption of a Plant-Based and Lean Proteins pattern had earlier sleep timing (−0.45 h with 95% Confidence Interval (CI) −0.81, −0.08 in the highest compared to lowest quartiles), less of a phase delay in sleep timing over follow-up (−0.39 h with 95% CI −0.80, 0.02), and shorter weekend sleep duration (0.5 h with 95% CI −0.88, −0.1). Higher consumption of an Eggs, Milk and Refined Grain pattern was associated with earlier sleep timing (−0.40 h with 95% CI −0.77, −0.04), while consumption of a Meat and Starchy pattern was related to higher social jetlag (weekend–weekday sleep timing difference). Healthier diet patterns may promote better sleep in adolescents.

Abstract P515: Comparison of Dietary Measures Association With Incident Type 2 Diabetes: The Reasons for Geographic and Racial Differences in Stroke (regards) Study

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Stephanie Tison ◽  
April P Carson ◽  
James M Shikany ◽  
Keith Pearson ◽  
George Howard ◽  
...  
Keyword(s):  
Racial Differences ◽  
Mediterranean Diet ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
A Priori ◽  
Incident Diabetes ◽  
A Posteriori ◽  
Regards Study ◽  
Diet Score

Background: Previous studies have investigated the association of dietary patterns with risk of diabetes, but have not compared a priori and a posteriori dietary scores in the same diverse population. The objective of this study was to evaluate a priori and a posteriori dietary patterns associations with incident diabetes in the REGARDS study. Methods: This study included 8,875 Black and White adults with available dietary data, without diabetes (defined as fasting glucose>=126 mg/dL, random glucose>=200 mg/dL, or use of diabetes medications) at baseline (2003-2007), and with follow-up (2013-2016) status of diabetes. Dietary patterns were examined by quintile and included a posteriori Plant-based and Southern, as well as a priori scores of Mediterranean Diet Score, Dietary Approaches to Stop Hypertension (DASH) Diet Score, Dietary Inflammatory Index (DII) and Dietary Inflammation Score (DIS). Modified Poisson regression was used to obtain risk ratios for incident diabetes with models adjusted for total energy intake, demographics, and lifestyle factors. Results: The mean (SD) age at baseline was 63.2 (8.5) years, 27.1% were Black, 56.2% were female, and 11.7% had incident diabetes at follow-up. Adherence to the Southern dietary pattern was positively associated with incident diabetes for all models (figure). After adjustment for demographic factors, the highest quintiles of DII and DIS were associated with incident diabetes and the highest quintiles of DASH scores were protective of development of incident diabetes. Conclusion: The Southern dietary pattern derived in REGARDS showed the strongest association with incident diabetes of all the dietary scores and of the a priori scores the DIS showed the strongest association with incident diabetes. The lack of association in adjusted models with the Mediterranean Diet and Plant-based pattern show these scores to be less pertinent. The DIS demonstrates food based dietary inflammation as one of the potential pathways for incident diabetes.

Abstract 36: The Role of Sleep as a Cardiovascular Health Metric: Does It Improve Cardiovascular Disease Risk Prediction? Results From The Multi-Ethnic Study of Atherosclerosis

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Nour Makarem ◽  
Cecilia Castro-Diehl ◽  
Marie-Pierre St-Onge ◽  
Susan Redline ◽  
Steven Shea ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Sleep Duration ◽  
Risk Prediction ◽  
Cardiovascular Health ◽  
Cvd Risk ◽  
Sleep Study ◽  
Lower Odds ◽  
Wrist Actigraphy ◽  
Incident Cases

Background: The AHA Life’s Simple 7 (LS7) is a measure of cardiovascular health (CVH). Sufficient and healthy sleep has been linked to higher LS7 scores and lower cardiovascular disease (CVD) risk, but sleep has not been included as a CVH metric. Hypothesis: A CVH score that includes the LS7 plus sleep metrics would be more strongly associated with CVD outcomes than the LS7 score. Methods: Participants were n=1920 diverse adults (mean age: 69.5 y) in the MESA Sleep Study who completed 7 days of wrist actigraphy, overnight in-home polysomnography, and sleep questionnaires. Logistic regression and Cox proportional hazards models were used to compare the LS7 score and 4 new CVH scores that incorporate aspects of sleep in relation to CVD prevalence and incidence (Table). There were 95 prevalent CVD events at the Sleep Exam and 93 incident cases during a mean follow up of 4.4y. Results: The mean LS7 score was 7.3, and the means of the alternate CVH scores ranged from 7.4 to 7.8. Overall, 63% of participants slept <7h, 10% had sleep efficiency <85%, 14% and 36% reported excess daytime sleepiness and insomnia, respectively, 47% had obstructive sleep apnea, and 39% and 25% had high night-to-night variability in sleep duration and sleep onset timing. The LS7 score was not significantly associated with CVD prevalence or incidence (Table). Those in the highest vs. lowest tertile of CVH score 1, that included sleep duration, and CVH score 2, that included sleep characteristics linked to CVD in the literature, had lower odds of prevalent CVD. Those in the highest vs. lowest tertile of CVH scores 3 and 4, which included sleep characteristics linked to cardiovascular risk in MESA, had lower odds of prevalent CVD and lower risk of developing CVD. Conclusions: CVH scores that include sleep were more strongly associated with CVD prevalence and incidence than the traditional LS7 score. The incorporation of sleep as a metric of CVH, akin to other health behaviors, may improve CVD risk prediction. Findings warrant confirmation in larger samples and over longer follow-up.

scholarly journals Plasma DHA Is Related to Sleep Timing and Duration in a Cohort of Mexican Adolescents

2019 ◽  
Vol 150 (3) ◽  
pp. 592-598 ◽  
Author(s):  
Erica C Jansen ◽  
Deirdre A Conroy ◽  
Helen J Burgess ◽  
Louise M O'Brien ◽  
Alejandra Cantoral ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Sleep Duration ◽  
Linear Regression Analysis ◽  
Plasma Concentrations ◽  
Cross Sectional ◽  
Public Health Burden ◽  
Sleep Timing ◽  
Wrist Actigraphy ◽  
Total Fatty Acids ◽  
Mexican Adolescents

ABSTRACT Background Delayed sleep timing and short sleep duration represent a significant public health burden in adolescents. Whether intake of nutrients affects the pineal gland, where sleep/wake cycles are regulated, remains unclear. Objectives In a cross-sectional analysis, we investigated whether plasma concentrations of DHA and arachidonic acid (AA), long-chain fatty acids that can be obtained through diet, were related to sleep timing and duration in adolescents. Methods The study population included 405 Mexico City adolescents (mean age ± SD = 14.2 ± 2.1 y; 48% males) who took part in a 2015–2016 follow-up visit as a part of an ongoing cohort study. Fatty acid concentrations were measured in plasma using GLC, as a percentage of total fatty acids. Sleep midpoint and duration were assessed with 7-d wrist actigraphy. We categorized DHA and AA plasma concentrations into quartiles (Q1–Q4; Q4 = highest fatty acids). We conducted cross-sectional linear regression analysis with sleep characteristics as separate outcomes and quartiles of DHA and AA as exposures, adjusting for sex, age, and BMI z-scores. Results Mean ± SD plasma DHA (as percentage of total fatty acids) was 1.2 ± 0.4%, whereas mean ± SD plasma AA was 6.2 ± 1.5%. In adjusted analysis, higher plasma DHA was linearly associated with longer sleep duration on the weekends; to illustrate, those in Q4 compared with Q1 had 32 min longer duration (95% CI: 7, 57; P trend = 0.005). Higher DHA was also associated with earlier sleep timing during weekdays and weekends, although in a nonlinear fashion. The largest difference was a 0.75-h (45-min) later sleep midpoint in Q2 compared with Q4 (95% CI: 0.36, 1.14). Conclusions Plasma DHA was associated with earlier sleep timing and longer weekend sleep duration in Mexican adolescents. Whether DHA supplementation improves sleep in adolescent populations deserves consideration in randomized trials.

scholarly journals Dietary patterns and nutritional adequacy in a Mediterranean country

2009 ◽  
Vol 101 (S2) ◽  
pp. S21-S28 ◽  
Author(s):  
Lluís Serra-Majem ◽  
Maira Bes-Rastrollo ◽  
Blanca Román-Viñas ◽  
Karina Pfrimer ◽  
Almudena Sánchez-Villegas ◽  
...  
Keyword(s):  
Folic Acid ◽  
Dietary Patterns ◽  
Nutrient Intake ◽  
Principal Component ◽  
Vitamin B ◽  
Mediterranean Country ◽  
A Posteriori ◽  
Diet Patterns ◽  
Study Participants ◽  
Adequate Nutrient

Dietary patterns have been related to health outcomes and morbi-mortality. Mediterranean diet indexes are correlated with adequate nutrient intake. The objective of the present study was to analyse the adequacy of nutrient intake ofa posterioridefined Mediterranean (MDP) and Western (WDP) diet patterns in the Seguimiento Universidad de Navarra (SUN) cohort. A sample of 17 197 subjects participated in the study. Participants completed a 136-item validated semi-quantitative FFQ. Principal component analysis was used to define dietary patterns. Individuals were classified according to quintiles of adherence based on dietary pattern scores. Non-dietary variables, such as smoking and physical activity habits, were also taken into account. The probability approach was used to assess nutrient intake adequacy of certain vitamins (vitamins B12, B6, B3, B2, B1, A, C, D and E) and minerals (Na, Zn, iodine, Se, folic acid, P, Mg, K, Fe and Ca). Logistic regression analysis was used to assess the adequacy of nutrient intake according to adherence to dietary patterns. WDP and MDP were defined. A higher quintile of adherence to an MDP was associated to a lower prevalence of inadequacy for the intake of Zn, iodine, vitamin E, Mg, Fe, vitamin B1, vitamin A, Se, vitamin C and folic acid. The adjusted OR for not reaching at least six (or at least ten) nutrient recommendations were 0·09 (95 % CI: 0·07, 0·11) (and 0·02 (95 % CI: 0·00, 0·16)) for the upper quintile of MDP and 4·4 (95 % CI: 3·6, 5·5) and 2·5 (95 % CI: 1·1, 5·4) for the WDP. The MDP was associated to a better profile of nutrient intake.

scholarly journals The Mediterranean Diet Protects the Renal Function in Older Adults: A Prospective Cohort Study

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 562-562
Author(s):  
Helena Sandoval-Insausti ◽  
Ana Bayan-Bravo ◽  
Carolina Donat-Vargas ◽  
Jimena Rey-Garcia ◽  
Jose Ramon Banegas ◽  
...  
Keyword(s):  
Renal Function ◽  
Cohort Study ◽  
Mediterranean Diet ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Prospective Cohort ◽  
A Posteriori ◽  
High Adherence ◽  
The Mediterranean

Abstract Objectives It is not clear if the adherence to a Mediterranean diet is associated with changes in kidney function. The aim of this study is to assess the prospective association between the adherence to the Mediterranean diet and renal function decline. Methods Prospective cohort study of 975 community-dwelling individuals aged 60 and older who were recruited during 2008–10 in Spain, and followed up to December, 2015. At baseline, food consumption was obtained with a validated, computerized face-to-face diet history. The “a priori” adherence to the Mediterranean diet was assessed with the Mediterranean Diet Adherence Screener (MEDAS score: low adherence 0–5 points, moderate adherence 6–8 points, high adherence 9–14 points). To identify “a posteriori” dietary patterns, 880 foods were categorized into 36 different groups according to similarities in their nutritional profile. Factor analysis (principal components analysis) was applied to generate independent dietary patterns. At baseline and at the end of follow-up, serum creatinine (SC) and glomerular filtration rate (GFR) levels were ascertained and changes were calculated. Two end-points were considered: SC increase and GFR decrease beyond that expected for age. Logistic regression models were built and adjusted for prevalent and incident cardiovascular risk factors. Results At the end of follow-up 150 cases of SC increase and 146 cases of GFR decrease occurred. The fully adjusted ORs (95% CI) of SC increase were 0.75 (0.49–1.15) for participants with a moderate adherence to the MEDAS score, and 0.58 (0.36–0.95) for those with a high adherence, when comparing to participants with a low adherence; (p-trend: 0.026). Results for GFR decrease had the same direction (p-trend: 0.049). The fully adjusted ORs (95% CI) of SC increase according to increasing quartiles of adherence to an “a posteriori” Mediterranean-like dietary pattern were 1.00, 0.62 (0.37–1.03), 0.57 (0.33–0.99), and 0.46 (0.24–0.86); (p-trend: 0.017). Results for GFR decrease were similar (p-trend: 0.007). Conclusions A higher adherence to a Mediterranean dietary pattern was associated with a lower risk of kidney function decline. Funding Sources State Secretary of R + D and FEDER/FSE, the ATHLOS project (EU H2020), and the CIBERESP, Instituto de Salud Carlos III. Madrid, Spain.

scholarly journals Adherence to a plant-based, high-fibre dietary pattern is related to regression of non-alcoholic fatty liver disease in an elderly population

2020 ◽  
Vol 35 (11) ◽  
pp. 1069-1085 ◽  
Author(s):  
Louise J. M. Alferink ◽  
Nicole S. Erler ◽  
Robert J. de Knegt ◽  
Harry L. A. Janssen ◽  
Herold J. Metselaar ◽  
...  
Keyword(s):  
Liver Disease ◽  
Dietary Patterns ◽  
Fatty Liver Disease ◽  
Elderly Population ◽  
A Priori ◽  
A Posteriori ◽  
Alcoholic Fatty Liver ◽  
High Fibre ◽  
Alcoholic Fatty Liver Disease

AbstractDietary lifestyle intervention is key in treating non-alcoholic fatty liver disease (NAFLD). We aimed to examine the longitudinal relation between well-established dietary patterns as well as population-specific dietary patterns and NAFLD. Participants from two subsequent visits of the Rotterdam Study were included. All underwent serial abdominal ultrasonography (median follow-up: 4.4 years) and filled in a food frequency questionnaire. Secondary causes of steatosis were excluded. Dietary data from 389 items were collapsed into 28 food groups and a posteriori dietary patterns were identified using factor analysis. Additionally, we scored three a priori dietary patterns (Mediterranean Diet Score, Dutch Dietary Guidelines and WHO-score). Logistic mixed regression models were used to examine the relation between dietary patterns and NAFLD. Analyses were adjusted for demographic, lifestyle and metabolic factors. We included 963 participants of whom 343 had NAFLD. Follow-up data was available in 737 participants. Incident NAFLD was 5% and regressed NAFLD was 30%. We identified five a posteriori dietary patterns (cumulative explained variation [R2] = 20%). The patterns were characterised as: vegetable and fish, red meat and alcohol, traditional, salty snacks and sauces, high fat dairy & refined grains pattern. Adherence to the traditional pattern (i.e. high intake of vegetable oils/stanols, margarines/butters, potatoes, whole grains and sweets/desserts) was associated with regression of NAFLD per SD increase in Z-score (0.40, 95% CI 0.15–1.00). Adherence to the three a priori patterns all showed regression of NAFLD, but only the WHO-score showed a distinct association (0.73, 95% CI 0.53–1.00). Hence, in this large elderly population, adherence to a plant-based, high-fibre and low-fat diet was related to regression of NAFLD.

scholarly journals Sex Moderates Relationships Among School Night Sleep Duration, Social Jetlag, and Depressive Symptoms in Adolescents

2019 ◽  
Vol 34 (2) ◽  
pp. 205-217 ◽  
Author(s):  
Gina Marie Mathew ◽  
Lauren Hale ◽  
Anne-Marie Chang
Keyword(s):  
Depressive Symptoms ◽  
Sleep Duration ◽  
Total Sleep Time ◽  
Emotional Health ◽  
Depression Scale ◽  
Sleep Time ◽  
Epidemiologic Studies ◽  
Female Adolescents ◽  
Sleep Timing ◽  
Social Jetlag

Social jetlag, a misalignment between sleep timing on the weekend and during the work week, is associated with depressive symptoms among adults across both sexes. A previous study found that later sleep timing was associated with depressive symptoms in women but not men. To date, however, no research has investigated whether the association between social jetlag and depression varies by sex among adolescents. The current study assessed self-reported sleep, depressive symptoms, and demographic information from 3058 adolescents (48% female, mean [SD] age 15.59 [0.77] years) from the age 15 wave of the Fragile Families and Child Wellbeing Study (FFCWS). Social jetlag was calculated as the absolute value of the midpoint of sleep on the weekend minus the midpoint of sleep during the school week. Depressive symptoms were measured through a modified 5-item version of the Center for Epidemiologic Studies Depression Scale (CES-D). We assessed whether the associations among sleep duration on school nights, social jetlag, and depressive symptoms were similar between male and female adolescents using multiple linear regression. In fully adjusted models, sex moderated the association between school night total sleep time and depressive symptoms ( p < 0.001) and between social jetlag and depressive symptoms ( p = 0.037). In females, but not in males, school night total sleep time was negatively associated with depressive symptoms ( p < 0.001), whereas social jetlag ( p < 0.001) was positively and independently associated with depressive symptoms. The results indicate the importance of regular sleep timing across the week and adequate sleep duration for the maintenance of optimal emotional health among female adolescents.

scholarly journals Long Sleep Duration and Social Jetlag Are Associated Inversely with a Healthy Dietary Pattern in Adults: Results from the UK National Diet and Nutrition Survey Rolling Programme Y1–4

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1131 ◽  
Author(s):  
Suzana Almoosawi ◽  
Luigi Palla ◽  
Ian Walshe ◽  
Snieguole Vingeliene ◽  
Jason Ellis
Keyword(s):  
Sleep Duration ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Survey Design ◽  
Nutrition Survey ◽  
Social Jetlag ◽  
Long Sleep ◽  
Nationally Representative ◽  
The Uk ◽  
Healthy Dietary Pattern

Limited observational studies have described the relationship between sleep duration and overall diet. The present study investigated the association between sleep duration on weekdays or social jetlag and empirically derived dietary patterns in a nationally representative sample of UK adults, aged 19–64 years old, participating in the 2008–2012 UK National Diet and Nutrition Survey Rolling Programme. Survey members completed between three to four days of dietary records. Sleep duration on weekdays was categorized into tertiles to reflect short, normal, and long sleep duration. Social jetlag was calculated as the difference between sleep duration on weekends and weekdays. The association between sleep duration/social jetlag and dietary patterns, derived by principal components analysis, was assessed by regressing diet on sleep, whilst accounting for the complex survey design and adjusting for relevant confounders. Survey members in the highest tertile of sleep duration had on average a 0.45 (95% Confidence Interval (CI) −0.78, −0.12) lower healthy dietary pattern score, compared to middle tertile (p = 0.007). There was an inverted u-shaped association between social jetlag and the healthy dietary pattern, such that when sleep on weekends exceeded weekday sleep by 1 h 45 min, scores for indicating a healthy dietary pattern declined (p = 0.005). In conclusion, long sleep duration on weekdays and an increased social jetlag are associated with a lower healthy dietary pattern score. Further research is required to address factors influencing dietary patterns in long sleepers.

scholarly journals A posteriori Dietary Patterns in 71-year old Swedish Men and the Prevalence of Sarcopenia 16 Years Later

2021 ◽  
pp. 1-28
Author(s):  
Mikael Karlsson ◽  
Wulf Becker ◽  
Tommy Cederholm ◽  
Liisa Byberg
Keyword(s):  
Dietary Patterns ◽  
Fermented Milk ◽  
A Posteriori ◽  
High Intake ◽  
Adult Men ◽  
High Consumption ◽  
European Working ◽  
Old Swedish

Abstract The role of diet in sarcopenia is unclear and results from studies using dietary patterns (DPs) are inconsistent. We assessed how adherences to a posteriori DPs are associated with the prevalence of sarcopenia and its components 16 years later. Four DPs were defined in the Uppsala Longitudinal Study of Adult Men at baseline (n= 1133, average age 71 years). Among 257 men with information at follow-up, 19% (n=50) had sarcopenia according to the European Working Group on Sarcopenia in Older People (EWGSOP) 2 definition. Adherence to DP2 (mainly characterized by high intake of vegetables, green salad, fruit, poultry, rice and pasta) was non-linearly associated with sarcopenia; adjusted odds ratios (ORs) and 95% confidence intervals (CI) for medium and high vs low adherence: 0.41 (0.17-0.98) and 0.40 (0.17-0.94). The OR per standard deviation (SD) higher adherence to DP2 was 0.70 (0.48 - 1.03). Adjusted ORs (95% CIs) for 1 SD higher adherence to DP1 (mainly characterized by high consumption of milk and cereals), DP3 (mainly characterized by high consumption of bread, cheese, marmalade, jam and sugar) and DP4 (mainly characterized by high consumption of potatoes, meat and egg, and low consumption of fermented milk) were 1.04 (0.74 - 1.46), 1.19 (0.71 - 2.00) and 1.08 (0.77 - 1.53), respectively. There were no clear associations between adherence to the DPs and muscle strength, muscle mass, physical performance or sarcopenia using EWGSOP1 (sarcopenia n=54). Our results indicate that diet may be a potentially modifiable risk factor for sarcopenia in old Swedish men.

scholarly journals 235 Age and Chronotype Associated with Sleep Timing Changes During COVID-19-Related Lockdowns in the US

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A94-A94
Author(s):  
Ryan Bottary ◽  
Eric Fields ◽  
Elizabeth Kensinger ◽  
Tony Cunningham
Keyword(s):  
Sleep Duration ◽  
Sleep Onset ◽  
Onset Time ◽  
The United States ◽  
Open Science ◽  
Period Change ◽  
Sleep Patterns ◽  
Sleep Timing ◽  
Social Jetlag ◽  
The Us

Abstract Introduction Global lockdowns implemented to reduce spread of the Coronavirus Disease 2019 (COVID-19) have offered unique insight into how sleep patterns change when typical social obligations are significantly reduced. Here, we aimed to replicate findings of sleep timing delays and reduced social jetlag during lockdown using a large, regionally-diverse sample of participants from the United States (US). Further, we conducted exploratory analyses to determine if observed sleep changes were associated with age and self-reported chronotype. Methods A sample of 691 US adults (age 18-89) completed the Ultrashort Munich Chronotype Questionnaire twice during the same assessment: once querying retrospective memory for sleep patterns in the 6-weeks prior to February 1, 2020 (Pre-Lockdown) and a second time for sleep patterns in the 6-weeks prior to ~May 20th (Peak-Lockdown in the US). Participants also completed the abbreviated Morningness-Eveningness Questionnaire to assess chronotype. We compared sleep duration (SDur), sleep onset time (SO), sleep end time (SEnd), social jetlag (SJL; difference between work-day and free-day sleep midpoint) and social sleep restriction (SSR; difference between work-day and free-day sleep duration) Pre- to Peak-Lockdown. We conducted exploratory analyses to determine whether Pre- to Peak-Lockdown changes in these sleep metrics were associated with age or chronotype. Main analyses were preregistered with Open Science Framework (https://osf.io/4a3fx). Results During the Peak-Lockdown period, participants, on average, reported significantly later SO and SEnd times and significantly reduced SJL and SSR compared with the Pre-Lockdown period. Change in SJL and SSR Pre- to Peak-Lockdown was significantly positively associated with age and chronotype such that SJL and SSR decreased more during lockdown in younger participants and those with an evening chronotype. Conclusion Our results support lockdown-associated sleep timing delays and reduced SJL and SSR. Younger age and evening chronotype were associated with greater reductions in SJL and SSR during lockdown. These findings suggest that individuals, particularly young individuals and those with an evening chronotype, experience greatest desynchrony between intrinsic and social sleep timing when conforming to typical pre-pandemic social schedules. Support (if any) Harvard Medical School Division of Sleep Medicine T32 HL007901 (RB and TJC); Brandeis University NIH NRSA T32 NS007292 (ECF)

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