scholarly journals Coix Seed Consumption Affects the Gut Microbiota and the Peripheral Lymphocyte Subset Profiles of Healthy Male Adults

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4079
Author(s):  
Minami Jinnouchi ◽  
Taisei Miyahara ◽  
Yoshio Suzuki

A systematic examination of the effects of traditional herbal medicines including their mechanisms could allow for their effective use and provide opportunities to develop new medicines. Coix seed has been suggested to promote spontaneous regression of viral skin infection. Purified oil from coix seed has also been suggested to increase the peripheral CD4+ lymphocytes. We, herein, attempt to shed more light on the way through which coix seed affects the human systemic immune function by hypothesizing that a central role to these changes could be played through changes in the gut microbiota. To that end, healthy adult males (n = 19) were divided into two groups; 11 of them consumed cooked coix seed (160 g per day) for 7 days (intervention), while the other eight were given no intervention. One week of coix seed consumption lead to an increase of the intestinal Faecalibacterium abundance and of the abundance (as % presence of overall peripheral lymphocytes) of CD3+CD8+ cells, CD4+ cells, CD4+CD25+ cells, and naïve/memory T cell ratio. As the relationship of microbiota and skin infection has not been clarified, our findings could provide a clue to a mechanism through which coix seed could promote the spontaneous regression of viral skin infections.

2018 ◽  
Vol 9 (2) ◽  
pp. 193-199
Author(s):  
Tamariani Manullang

Prevalence of hypertension in adult males was highest in PuskesmasBasuki Rahmat (16.2%) as many as 648 cases of hypertension patients which hasincreased compared to 2012 by 12% in cases of hypertension totaled 482 patients((Dinkes Kota, 2013). This study aims to determine the relationship of body massindex (BMI) and waist circumference (WC) with systolic blood pressure (BP) in adultmales in Puskesmas Basuki Rahmat Bengkulu City in 2015. The study design wasdescriptive analytic with cross sectional approach. Study location was in PuskesmasBasuki Rahmat City of Bengkulu. Samples were selected using purposive samplingtotalling 68 people. Criterias sample were being adult males who occupied inPuskesmas Basuki Rahmat City of Bengkulu, aged ≥ 18 years, agreed to beinterviewed,and able to communicate actively. Data were obtained include BMI, WCand systolic BP adult males and processed using computer software with pearsoncorrelation analysis.The results showed that there was relationship between BMI andsystolic BP (p = 0.0005; r = 0.395); between WC and systolic BP (p = 0.004 and r =0.347) in adult males. This study concluded that there was relationship between BMIand WC with systolic BP in adult males in Puskesmas Basuki Rahmat Bengkulu Cityin 2015.


1986 ◽  
Vol 64 (10) ◽  
pp. 2075-2080 ◽  
Author(s):  
Gregory K. Silber

Humpback whale (Megaptera novaeangliae) social vocalizations (nonsong sounds) were clearly related to whale group size and surface activity. Social sounds occurred almost exclusively in groups containing three or more whales and were rarely heard near single whales, pairs, or cow–calf groups. Large groups (3 to 20 individuals) vocalized at an overall mean rate of 43.1 ± 55.52 sounds per whale/h. Group size changed frequently and a dramatic increase in vocalization rate resulted when a new whale entered a group. Large groups engaged in flurries of surface activity, such as breaching, flipper- and tail-slapping, and underwater bubbling. Aggressive encounters resulted from male–male interaction. Social sounds probably acted to demonstrate aggression or agitation as adult males competed for temporary social dominance within the group and for proximity to the female. Likewise, visual displays may have been used as threats in close quarters and were apparently produced in conjunction with sounds to convey levels of aggression. Although other studies suggested that surface activity increased with group size, I found a negative correlation between activity and group size, both in the group as a whole and per individual. In contrast, social vocalizations per group increased with group size while the vocalization rate per individual did not vary significantly with increasing group size.


2021 ◽  
Vol 76 (1) ◽  
pp. 75-85
Author(s):  
Victoria O. Bitsadze ◽  
Ekaterina V. Slukhanchuk ◽  
Jamilya H. Khizroeva ◽  
Maria V. Tretyakova ◽  
Andrei S. Shkoda ◽  
...  

This article summarizes numerous studies on the relationship of biological processes such as inflammation and thrombosis. The huge role of neutrophils and the extracellular neutrophil traps (NETs) secreted by them has been demonstrated. The discovery of NETs has opened new horizons in the understanding of neutrophil biology and the role of these cells in the body. The use of chromatin in combination with the intracellular proteins, as an effective antimicrobial agent has ancient roots and changes our understanding of chromatin only as a carrier of genetic information. Through NETs, neutrophils can contribute to the development of pathological venous and arterial thrombosis or immunothrombosis, as well as atherosclerosis. NETs release has been shown to be one of the causes of thrombosis in conditions such as sepsis and cancer. The presence of NETs in these diseases and conditions makes it possible to use them or individual components as potential biomarkers. NETs and their components may be attractive as therapeutic targets. Further studies of neutrophils and NETs are needed to develop new approaches to the diagnosis and treatment of inflammatory and thrombotic conditions. Perhaps long-forgotten drugs will find a new area for effective use.


Author(s):  
Putu Eka Arimbawa ◽  
Dewi Puspita Apsari ◽  
I Gusti Ngurah Agung Windra Wartana Putra ◽  
Muhammad Iqbal Fasa

Pharmaceutical services are services provided by a pharmacist in providing health information including the use of herbal medicines. The purpose of this study was to look at the relationship between pharmaceutical services and the use of herbal medicines in the city of Denpasar. The number of samples used was 97. Data were collected from January to February 2020 in the city of Denpasar using a questionnaire. Data were analyzed using the binary logistic test. The results showed that pharmaceutical services did not have a significant relationship with the use of herbal medicines (P> 0.05). Pharmaceutical services such as completeness of the drug, pharmacist's readiness to assist, and the speed of drug preparation services that are less good can affect the physical, mental, and spiritual aspects of herbal medicine.


2020 ◽  
pp. 467-476
Author(s):  
R. Pasko

The concepts of most efficient use (MEU) of real estate objects and functional wear and tear are closely interrelated and cannot be considered separately. The application of the MEU principle allows the expert to account for this type of wear and, vice versa, without the wear and tear, the expert cannot properly apply the MEU principle in all approaches. In the article, special attention is paid to the scheme of interaction of MEU analysis with valuation approaches through the elimination of wear and the connection of the latter with the concepts of reconstruction, modernization and repair of the object of assessment. The performance (characteristics) of buildings and structures, which are the main objects of functional wear, are considered. The place of functional wear in the structure of the accumulated wear of the objects of evaluation is shown. Ways of simplification of calculation, the situations in which it is recommended to take into account wear are considered.


PEDIATRICS ◽  
1951 ◽  
Vol 8 (4) ◽  
pp. 522-526
Author(s):  
JOHN GRUHN ◽  
ELLIOTT S. HURWITT

A case of sternomastoid tumor of infancy is described which presented clinically as a neck mass without torticollis and simulated a neoplasm. Four aspects of the problem are discussed: (1) the relationship of tumor and torticollis; (2) the etiology and pathogenesis; (3) the differential diagnosis from sarcoma; and (4) the treatment. Prophylactic resection of the mass to exclude a possible malignant tumor or to prevent the subsequent development of torticollis, is not justified, since in about 80% of cases spontaneous regression occurs without sequelae. The institution of passive neck exercises over a period of several months during and following degression of the mass may contribute to a decreased incidence of deformities.


Zootaxa ◽  
2009 ◽  
Vol 2169 (1) ◽  
pp. 21-34
Author(s):  
GREGORY R. CURLER

Gondwanoscurus Jezek (Psychodidae: Psychodinae) is revised to include seven species. Gondwanoscurus cruciferus sp. nov. and G. ornithostylus sp. nov. from Thailand are described. Three described species are transferred from Telmatoscopus Eaton to Gondwanoscurus: G. ejundicus (Quate), G. eximius (Quate) and G. praecipuus (Quate). The adult male and female of G. ejundicus and G. mcclurei (Quate) and the adult male of G. eximius and G. praecipuus are redescribed. Keys to adult males of the seven known species and females of the four species for which they are known are provided, and the relationship of Gondwanoscurus to other Paramormiine genera is discussed.


2019 ◽  
Vol 130 (5) ◽  
pp. 1728-1739 ◽  
Author(s):  
Christos Koutsarnakis ◽  
Aristotelis V. Kalyvas ◽  
Spyridon Komaitis ◽  
Faidon Liakos ◽  
Georgios P. Skandalakis ◽  
...  

OBJECTIVEThe authors investigated the specific topographic relationship of the optic radiation fibers to the roof and floor of the ventricular atrium because the current literature is ambiguous.METHODSThirty-five normal, adult, formalin-fixed cerebral hemispheres and 30 focused MRI slices at the level of the atrium were included in the study. The correlative anatomy of the optic radiation with regard to the atrial roof and floor was investigated in 15 specimens, each through focused fiber microdissections. The remaining 5 hemispheres were explored with particular emphasis on the trajectory of the collateral sulcus in relation to the floor of the atrium. In addition, the trajectory of the collateral sulcus was evaluated in 30 MRI scans.RESULTSThe atrial roof was observed to be devoid of optic radiations in all studied hemispheres, whereas the atrial floor was seen to harbor optic fibers on its lateral part. Moreover, the trajectory of the intraparietal sulcus, when followed, was always seen to correspond to the roof of the atrium, thus avoiding the optic pathway, whereas that of the collateral sulcus was found to lead to either the lateral atrial floor or outside the ventricle in 88% of the cases, therefore hitting the visual pathway.CONCLUSIONSOperative corridors accessing the ventricular atrium should be carefully tailored through detailed preoperative planning and effective use of intraoperative navigation to increase patient safety and enhance the surgeon’s maneuverability. The authors strongly emphasize the significance of accurate anatomical knowledge.


2018 ◽  
Author(s):  
Xing Liu ◽  
Kai Fan ◽  
Wei-Guo Song ◽  
Zhengwu Wang

This study investigated the optimization of accelerated solvent extraction (ASE) of fatty acids (FAs) from three Coix seeds (small Coix seed, SCS; big Coix seed, BCS; translucent Coix seed, TCS) by chemometrics methods. Partial least-squares regression (PLSR) and backpropagation neural network (BPNN) were applied to build models that reflect the relationship between content of FAs and extraction conditions (temperature, time, and extraction solvent). Genetic algorithms (GAs) and particle swarm optimization (PSO) were utilized to optimize the combination of extraction conditions. The composition of FAs was analysed by gas chromatography-mass spectrometry (GC-MS). The PLSR models could reflect the relationship of FA content in both BCS and SCS and extraction conditions well, while the BPNN model was more suitable for TCS. The optimal extraction conditions for BCS and SCS were obtained by GAs, whereas those of TCS were obtained by PSO. The FA compositions of the three Coix seeds exhibited differences. The results show that ASE combined with chemometrics methods can rapidly and effectively obtain the optimal conditions for the extraction of FAs from Coix seed and there are differences in the extraction conditions and compositions of FAs among different varieties of Coix seed, but all the extraction time is shorter than other extractions methods.


1993 ◽  
Vol 87 (6) ◽  
pp. 224-226 ◽  
Author(s):  
R.M. DeMott

This article suggests that the role of residential schools and the relationship of residential and local school programs should be reformed. If residential schools become resource and demonstration centers, they can provide for the more effective use of resources available in residential schools and increase the success of mainstreamed students with visual impairments in local schools.


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