Somatogenic depression in childhood and adolescence

2020 ◽  
pp. 29-35
Author(s):  
Yu. F. Antropov
Keyword(s):  
Risk Factors ◽  
Children And Adolescents ◽  
Statistical Methods ◽  
Clinical Features ◽  
High Frequency ◽  
Therapeutic Approach ◽  
Depressive Disorders ◽  
Significant Risk ◽  
Childhood And Adolescence ◽  
Somatic Disorders

The problem of somatogenic depressive disorders in childhood and adolescence remains urgent due to the high frequency and pronounced maladaptive effects. The purpose of the work was to clarify pathogenesis factors, frequency and clinical features of somatogenic affective (depressive) disorders in children and adolescents. 268 patients aged 1 to 17 years were studied using clinical-psychopathological, clinical-psychological and statistical methods. A high frequency (16,8 %) of somatogenic depression in the psychosomatic contingent, pathogenetically significant risk factors, as well as clinical features of somatogenic depressive disorders, were established. A certain association of somatogenic depressive and somatic disorders is emphasized, which makes it possible to substantiate a pathogenetically directed therapeutic approach.

scholarly journals Coxiella burnetii seroprevalence and risk factors in sheep farmers and farm residents in The Netherlands

2013 ◽  
Vol 142 (6) ◽  
pp. 1231-1244 ◽  
Author(s):  
M. M. A. De LANGE ◽  
B. SCHIMMER ◽  
P. VELLEMA ◽  
J. L. A. HAUTVAST ◽  
P. M. SCHNEEBERGER ◽  
...  
Keyword(s):  
Risk Factors ◽  
The Netherlands ◽  
Coxiella Burnetii ◽  
High Frequency ◽  
Significant Risk ◽  
Infection Risk ◽  
Multivariate Logistic Regression ◽  
Dairy Sheep ◽  
Sheep Farm ◽  
Farm Residents

SUMMARYIn this study, Coxiella burnetii seroprevalence was assessed for dairy and non-dairy sheep farm residents in The Netherlands for 2009–2010. Risk factors for seropositivity were identified for non-dairy sheep farm residents. Participants completed farm-based and individual questionnaires. In addition, participants were tested for IgG and IgM C. burnetii antibodies using immunofluorescent assay. Risk factors were identified by univariate, multivariate logistic regression, and multivariate multilevel analyses. In dairy and non-dairy sheep farm residents, seroprevalence was 66·7% and 51·3%, respectively. Significant risk factors were cattle contact, high goat density near the farm, sheep supplied from two provinces, high frequency of refreshing stable bedding, farm started before 1990 and presence of the Blessumer breed. Most risk factors indicate current or past goat and cattle exposure, with limited factors involving sheep. Subtyping human, cattle, goat, and sheep C. burnetii strains might elucidate their role in the infection risk of sheep farm residents.

Prevalence and risk factors of root resorption of adjacent teeth in maxillary canine impaction, among untreated children and adolescents

2018 ◽  
Vol 41 (5) ◽  
pp. 447-453 ◽  
Author(s):  
Frédéric Rafflenbeul ◽  
Catherine-Isabelle Gros ◽  
François Lefebvre ◽  
Sophie Bahi-Gross ◽  
Raphaëlle Maizeray ◽  
...  
Keyword(s):  
Risk Factors ◽  
Children And Adolescents ◽  
Root Resorption ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Data Sets ◽  
Maxillary Canine ◽  
3D Data ◽  
Potential Risk Factors ◽  
Associated Risk Factors

Summary Objectives The aim of this retrospective study was to assess in maxillary canine impaction cases both the prevalence of root resorption of adjacent teeth among untreated children and adolescents, and its associated risk factors. Subjects and methods Sixty subjects (mean age 12.2 years; SD 1.9; range 8–17 years) with 83 displaced maxillary canines and without any past or ongoing orthodontic treatment were included in this study. The presence of root resorption was evaluated on images from a single cone beam computed tomography (CBCT) unit. Potential risk factors were measured on the CBCT images and on panoramic reconstructions of the 3D data sets. The sample was characterized by descriptive statistics and multiple logistic regressions were performed to predict root resorption. Results Root resorption of at least one adjacent tooth was detected in 67.5 per cent of the affected quadrants. It was found that 55.7 per cent of the lateral incisors, 8.4 per cent of the central incisors, and 19.5 per cent of first premolars were resorbed. Of the detected resorptions, 71.7 per cent were considered slight, 14.9 per cent moderate, and 13.4 per cent severe. Contact between the displaced canine(s) and the adjacent teeth roots was the only identified statistically significant risk factor, all teeth being considered (odds ratio [OR] = 18.7, 95% confidence interval: 2.26–756, P < 0.01). An enlarged canine dental follicle, a peg upper lateral, or an upper lateral agenesis were not significantly associated with root resorption of adjacent teeth, nor were age nor gender. Conclusions Root resorption of adjacent teeth was detected in more than two-thirds of a sample of sixty untreated children and adolescents.

scholarly journals Novel Application of Statistical Methods to Identify New Urinary Incontinence Risk Factors

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Theophilus O. Ogunyemi ◽  
Mohammad-Reza Siadat ◽  
Suzan Arslanturk ◽  
Kim A. Killinger ◽  
Ananias C. Diokno
Keyword(s):  
Risk Factors ◽  
Urinary Incontinence ◽  
Longitudinal Data ◽  
Statistical Methods ◽  
Repeated Measures ◽  
Significant Risk ◽  
Large Data ◽  
Data Sets ◽  
Predictive Index ◽  
Urine Loss

Longitudinal data for studying urinary incontinence (UI) risk factors are rare. Data from one study, the hallmark Medical, Epidemiological, and Social Aspects of Aging (MESA), have been analyzed in the past; however, repeated measures analyses that are crucial for analyzing longitudinal data have not been applied. We tested a novel application of statistical methods to identify UI risk factors in older women. MESA data were collected at baseline and yearly from a sample of 1955 men and women in the community. Only women responding to the 762 baseline and 559 follow-up questions at one year in each respective survey were examined. To test their utility in mining large data sets, and as a preliminary step to creating a predictive index for developing UI, logistic regression, generalized estimating equations (GEEs), and proportional hazard regression (PHREG) methods were used on the existing MESA data. The GEE and PHREG combination identified 15 significant risk factors associated with developing UI out of which six of them, namely, urinary frequency, urgency, any urine loss, urine loss after emptying, subject’s anticipation, and doctor’s proactivity, are found most highly significant by both methods. These six factors are potential candidates for constructing a future UI predictive index.

scholarly journals Predisposing Factors for Deep Venous Thrombosis in Children and Adolescents with Nephrotic Syndrome

2011 ◽  
Vol 2011 ◽  
pp. 1-5
Author(s):  
Gabriela de Toledo Passos Candelaria ◽  
Vera Maria Santoro Belangero
Keyword(s):  
Risk Factors ◽  
Nephrotic Syndrome ◽  
Deep Vein Thrombosis ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Children And Adolescents ◽  
Odds Ratio ◽  
Significant Risk ◽  
Vein Thrombosis ◽  
Deep Vein

Nephrotic syndrome (NS) is a state of hypercoagulability. In this paper, we sought to determine risk factors for the occurrence of deep vein thrombosis (DVT) in children with NS. The “with DVT” group included patients with decompensated NS and diagnosed with DVT. The “without DVT” group included the same patients, six to eighteen months prior to the episode of DVT, with decompensated NS but without DVT. Different prediction variables were analyzed. The odds ratio for the occurrence of DVT in patients with triglyceride levels ≥300 mg/dL was 3.14 (95% CI 1.14 to 8.64). For hematocrit levels ≥43% and for the presence of infection or a severe systemic event, the odds ratio was 4.37 (95% CI 1.23 to 15.53). The presence of significant risk factors for the occurrence of DVT in children with NS may serve as a warning for the occurrence of venous thrombosis.

scholarly journals Characteristics, correlates, and outcomes of childhood and adolescent depressive disorders

2009 ◽  
Vol 11 (1) ◽  
pp. 45-62 ◽  
Keyword(s):  
Children And Adolescents ◽  
Depressive Disorders ◽  
Current Knowledge ◽  
Unipolar Depression ◽  
Depressive Illness ◽  
Developmental Differences ◽  
Natural Course ◽  
Response To Treatment ◽  
Childhood And Adolescence ◽  
Full Potential

Depressive illness beginning early in life can have serious developmental and functional consequences. Therefore, understanding the disorder during this developmental stage is critical for determining its etiology and course, as well as for developing effective intervention strategies. This paper summarizes current knowledge regarding the etiology, phenomenology, correlates, natural course, and consequences of unipolar depression in children and adolescents. Using adult depression as a framework, the unique aspects of childhood and adolescence are considered in order to better understand depression within a developmental context. The data suggest that the clinical presentation, correlates, and natural course of depression are remarkably similar across the lifespan. There are, however, important developmental differences. Specifically, the familial and psychological context in which depression develops in youngsters is associated with variability in the frequency and nature of depressive symptoms and comorbid conditions among children and adolescents. Maturational differences have also been identified in the neurobiological correlates of depression. These developmental differences may be associated with the observed variability in clinical response to treatment and longitudinal course. Characterization of the developmental differences will be helpful in developing more specific and effective interventions for youngsters, thereby allowing them to reach their full potential as adults.

Female genital tract rhabdomyosarcoma in childhood and adolescence: A single center experience.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e22518-e22518
Author(s):  
Inci Yaman Bajin ◽  
Tezer Kutluk ◽  
Ferah Yildiz ◽  
İbrahim Karnak ◽  
Berna Oğuz ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Clinical Features ◽  
Genital Tract ◽  
Early Stage ◽  
Female Genital Tract ◽  
Alveolar Type ◽  
Childhood And Adolescence ◽  
High Survival ◽  
Treatment Results ◽  
Female Genital

e22518 Background: Rhabdomyosarcoma is a rare tumor in children and adolescents, presenting 3% to 4% of all pediatric cancers. The female genital tract is considered as a favorable site of childhood RMS. The outcome has improved significantly during the last two decades, attributed to risk stratification and multimodality management of these challenging tumors. Here we present the clinical features and treatment results of girls with genital tract rhabdomyosarcoma to discuss. Methods: Fourteen girls with vaginal and uterine servical rhabdomyosarcoma younger than 18 years of age diagnosed and followed up between the years of 1995 and 2019 were included in this analysis. The clinical features and treatment results of patients were recorded from patient files and hospital information system retrospectively. Results: There were seven cases with vaginal and seven with uterin cervical carcinoma. All patients presented with polypoid masses protruding from the vagina. Median age of patients at diagnosis was 71 months (range 8-200 months). The IRS modified TNM staging was stage I for all the patients. All cases had embryonic type of RMS except one with alveolar type. All patients were treated with surgery and adjuvant chemotherapy, three received radiotherapy additionally. All achieved complete remission. Four patients experienced tumor relapse, 1 patient died with progressive disease. The median follow-up time was 75 months (7-271 months) for 13 patients who were alive with remission. Conclusions: Rhabdomyosarcoma is a rare sarcoma with a higher incidence in children and adolescents. With current treatment strategies, female genital tract rhabdomyosarcomas have a good prognosis. Favorable prognostic factors such as early stage at diagnosis and a favorable histology may contribute to the excellent observed survival. All parties who had involved on the care of these girls must be aware of the high survival with proper treatment to avoid treatment related morbidities and mortalities. Because of the rareness of the disease we wanted to share our experience.

National Cholesterol Education Program (NCEP): Highlights of the Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents

PEDIATRICS ◽  
1992 ◽  
Vol 89 (3) ◽  
pp. 495-501 ◽  
Author(s):  
Keyword(s):  
Risk Factors ◽  
Children And Adolescents ◽  
Expert Panel ◽  
The United States ◽  
Blood Cholesterol ◽  
Childhood And Adolescence ◽  
Cholesterol Levels ◽  
Chd Risk ◽  
Atherosclerotic Process ◽  
Chd Risk Factors

Compelling evidence exists that the atherosclerotic process begins in childhood and progresses slowly into adulthood, at which time it leads frequently to coronary heart disease (CHD), the major cause of death in the United States. Despite substantial success in reducing CHD mortality in the past two decades, the disease is still responsible for more than 500 000 deaths annually. About 20% of hospital discharges for acute CHD are for premature disease, ie, in patients younger than 55 years of age. Many of these adults have children who may have CHD risk factors that need attention. Estimates of the annual cost of CHD range from $41.5 to $56 billion. The Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents (which appears as a supplement to this issue of the journal) reviews the evidence that atherosclerosis or its precursors begin in young people; that elevated cholesterol levels early in life play a role in the development of adult atherosclerosis; that eating patterns and genetics affect blood cholesterol levels and CHD risk; and that lowering levels in children and adolescents will be beneficial. Cholesterol is the focus of the report, but other risk factors for atherosclerosis and CHD may originate early in life and should be addressed as well. Specifically, cigarette smoking should be discouraged; hypertension should be identified and treated; obesity should be avoided or reduced; regular aerobic exercise should be encouraged; and diabetes mellitus should be diagnosed and treated. SIGNIFICANCE OF BLOOD CHOLESTEROL LEVELS IN CHILDHOOD AND ADOLESCENCE

Aortic dissection in children and adolescents with Turner syndrome: risk factors and management recommendations

2015 ◽  
Vol 100 (7) ◽  
pp. 662-666 ◽  
Author(s):  
E J Turtle ◽  
A A Sule ◽  
D J Webb ◽  
L E Bath
Keyword(s):  
Risk Factors ◽  
At Risk ◽  
Aortic Dissection ◽  
Children And Adolescents ◽  
Turner Syndrome ◽  
Heart Defects ◽  
Childhood And Adolescence ◽  
Aortic Dilatation ◽  
Risk Of Death ◽  
Management Recommendations

There is a general lack of awareness of the risk of aortic dissection in Turner syndrome (TS) from both patients with TS and their physicians. Patients often ignore symptoms for up to 24 h before seeking medical advice, significantly increasing their risk of death. A clinical profile of those at risk of dissection is emerging and includes the presence of congenital heart defects, aortic dilatation and hypertension. MRI has revolutionised the visualisation of cardiovascular anatomy in TS but remains underutilised, especially in children and adolescents, and there is currently little guidance on blood pressure (BP) assessment or hypertension management. Children and adolescents with TS at risk of dissection could be easily identified by timely imaging and BP assessment. This would allow medical management or surgical intervention to be put in place to reduce the risk of this major, and often fatal, complication. Since guidance is lacking, we have reviewed the literature on the risk factors for dissection in TS during childhood and adolescence, and make recommendations on the assessment and management of these patients.

scholarly journals Clinical features of chronic bronchitis and genetic risk factors for the development of chronic obstructive pulmonary disease in adolescent smokers

2020 ◽  
Vol 73 (2) ◽  
pp. 250-253
Author(s):  
Svitlana I. Ilchenko ◽  
Anastasiia O. Fialkovska ◽  
Olena S. Koreniuk ◽  
Tatiana V. Yaroshevska ◽  
Nataliia M. Kramarenko ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Bronchitis ◽  
Clinical Features ◽  
Genetic Risk ◽  
Molecular Genetic ◽  
Genetic Risk Factors ◽  
Control Group ◽  
Chronic Obstructive ◽  
Childhood And Adolescence ◽  
Adolescent Smokers

The aim is to study the clinical features of the course of CB in adolescent smokers and to study the genetic risk factors for the development of COPD. Materials and methods: There were examined 40 adolescent smokers with CB, 30 never-smokers adolescents with CB and 37 healthy adolescents smokers (control group). The study included the collection of anamnesis, objective examination. calculation of the smoking index and the «pack/year», molecular genetic investigations. Results: It was proved that smoking leads to the development of chronic bronchitis as early as adolescence and affects its course, increasing the frequency and duration of exacerbations. We identified an association of the 2G/2G genotype of MMP1 gene with the development of chronic bronchitis in adolescent smokers. The TT genotype of CYP1A1 gene may be considered as a possible sustainability factor for the development of chronic bronchitis in adolescent smokers. Conclusions: The study of candidate genes for COPD in childhood and adolescence will facilitate the early detection of high-risk groups in the formation of this pathology, which will allow doctors to take the necessary preventive measures.

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