Physiotherapy technologies in rehabilitation programs in patients with urolithiasis before and after percutaneous nephroscopy

2021 ◽  
pp. 55-60
Author(s):  
V. N. Gornostaev ◽  
R. A. Gurtskoy
Keyword(s):  
Standard Therapy ◽  
Comparison Group ◽  
Polarized Light ◽  
Light Therapy ◽  
Early Postoperative Period ◽  
Ozone Therapy ◽  
Combined Use ◽  
Before And After ◽  
Blood Irradiation ◽  
Laser Blood Irradiation

Urinary stone disease (urolithiasis) is one of the most common urological diseases, the prevalence of which is growing every year, despite the development of new approaches to treatment. In recent decades, various endoscopic methods of treating urolithiasis, in particular, percutaneous nephroscopy, have become the most popular, however, even with such minimally invasive and non-invasive methods, the percentage of complications ranges from 5% to 11%. Despite the fairly widespread use of various physical factors in the urolithiasis treatment, it is still not possible to reduce the incidence rate. All this dictates an urgent need to search for new, more effective and safer, mainly non-drug technologies for the treatment of urolithiasis and prevention of the disease recurrence and postoperative complications. The aim of the study was to assess the effectiveness of the combined use of intravascular laser blood irradiation, ozone therapy, and light therapy (bioptron zepter) in the complex treatment of patients with urolithiasis after percutaneous lithotripsy, according to the data of ultrasound examination of the kidneys. Research materials. The study included 60 patients with urolithiasis who underwent percutaneous nephroscopy in the Urology Department of the PHI Railway Clinical Hospital “RZhD Meditsina”, Rostov-on-Don, in 2019–2020, with subsequent rehabilitation. The patients were divided into three relatively equivalent groups according to age, calculus size (from 7 to 20 mm), and stone composition. In the first (control) group, patients received standard therapy after surgery: antispasmodics, antibiotic therapy taking into account the bacterial culture of urine, non-steroidal anti-inflammatory drugs, which served as a background in the main group and the comparison group. In addition to the standard therapy, the patients in the second group (comparison group) underwent intravenous laser blood irradiation (ILBI) and ozone therapy. The patients of group 3 (main group) received intravenous laser blood irradiation (ILBI) and ozone therapy — 6 procedures each in the preoperative period against the background of standard therapy; polarized light and ILBI — 6 procedures each in the early postoperative period. Results. The article shows a higher efficacy of the combined use of ILBI, ozone therapy and light therapy in the complex treatment of patients with urolithiasis before and after percutaneous nephroscopy. Conclusion. Combined use of a course of intravenous laser blood irradiation (ILBI) and ozone therapy in the preoperative period and a course of polarized light and ILBI in the early postoperative period after percutaneous nephroscopy against the background of standard therapy in patients with urolithiasis contributes to a significant improvement in blood flow in the kidney and a reduction in the recovery period of the renal parenchyma, which made it possible to reduce the patient’s stay in the hospital, due to the prevention of the development of postoperative complications.

Experience in the use of physical factors during the recovery of the renal parenchyma after percutaneous nephroscopy

2021 ◽  
pp. 68-71
Author(s):  
V. N. Gornostaev ◽  
R. A. Gurtskoy ◽  
V. V. Shulzhenko
Keyword(s):  
Postoperative Period ◽  
Recovery Period ◽  
Polarized Light ◽  
Early Postoperative Period ◽  
Main Group ◽  
Renal Parenchyma ◽  
Control Group ◽  
Physical Factors ◽  
Ozone Therapy ◽  
Combined Use

The article reflects the results of the use of physical factors to restore the renal parenchyma in the early postoperative period after percutaneous nephroscopy in patients with urolithiasis. Material and methods: the study included 80patients with concretions of the renal pelvis after percutaneous nephroscopy (45men and 35women, average age — 46 years), who were divided into 2 comparable groups: groupI (main group) — 40 patients who underwent intravenous laser blood irradiation (ILBI) and ozone therapy — 6 procedures in the preoperative period, and polarized light and ILBI — 6 procedures in the early postoperative period; groupII (control group), which served as a background in the main group, were prescribed non-steroidal anti-inflammatory drugs after the surgery, taking into account bacterial urine culture. Inclusion criteria: patients with urolithiasis aged 28 to 62 years; indications for percutaneous nephroscopy. Exclusion criteria: concomitant diseases; compliance; pregnancy; acute inflammatory kidney diseases; abnormalities of the upper urinary tract. Results: The combined use of ILBI, ozone therapy and polarized light in the pre- and early postoperative period in patients with urolithiasis after percutaneous nephrolithotripsy allowed improving clinical, laboratory, subjective and objective indicators, as well as shortening the recovery period of the renal parenchyma, which was confirmed by the data of ultrasound studies in the dynamics in the form of a significant reduction in the recovery period of the index of renal vessels resistance and reduction of edema of the renal parenchyma. As a result of the application of the developed complex, the total bed-day of patients’ stay in the hospital decreased, and there was a rapid recovery of capacity to work. Conclusion: The developed method of the combined use of ILBI, ozone therapy and polarized light in the pre- and early postoperative period in patients with urolithiasis after percutaneous nephrolithiasis is pathogenetically justified and highly effective, which allows us to recommend it for wide use in urological practice.

The effect of the combined use of polarized light and immunomodulator on the cytokine profile in patients with HPV-associated cervicitis

2021 ◽  
pp. 56-65
Author(s):  
Gulnara Grigorievna Moseshvili ◽  
Nataliya Borisovna Korchazhkina ◽  
Madina Zaudinovna Dugieva
Keyword(s):  
Immune Response ◽  
Viral Load ◽  
Comparison Group ◽  
Polarized Light ◽  
Cytokine Profile ◽  
Cervical Mucus ◽  
Control Group ◽  
Incoherent Light ◽  
Healthy Women ◽  
Combined Use

Taking into account the literature data on the significance of the mucous membranes in providing an immune filter, and cervical mucus in providing an immune response due to the high content of the main mediators of the development of a local inflammatory response, i.e. anti-inflammatory cytokines, which play a major role in the regulation of the immune response and the formation of local antiviral and antitumor immunity, we studied the cytokine profile in patients with HPV-associated cervicitis and the effect of the combined use of polarized light and an immunomodulator on their content, depending on the viral load. The purpose of the work is to study the effect of the combined exposure to blue monochromatic polarized incoherent light and polychromatic visible and infrared polarized light in combination with Imiquimod 5% cream for external use on the state of the cytokine profile in the cervical mucus in patients with HPV-associated cervicitis. Material and methods. The study included 60 patients with an HPV-associated cervicitis with the history of at least 1 year, aged 20 to 35 years, who were randomly divided into three groups: the main group of 20 patients who underwent course exposure to blue monochromatic polarized incoherent light on the projection of the carotid arteries and polychromatic visible and infrared polarized light on the cervix in combination with Imiquimod 5% cream for external use (complex 1); a comparison group of 20 patients who underwent the exposure to polychromatic visible and infrared polarized light on the cervix in combination with the topical cream, Imiquimod 5% (complex 2); a control group of 20 patients who underwent a course of local effects on the cervix with the cream Imiquimod 5% and 20 healthy women of similar age, whose the survey data were taken as a norm. To assess the cytokine state in patients with HPV-associated cervicitis, the levels of IL-1β, IL-2, IL-10, IFNa, IFNy, and TNFa in the cervical mucus were studied before and after the course of treatment by the enzyme immunoassay method. The results of the research and the discussion. Prior to the treatment, certain differences were found depending on the viral load. In patients with a low viral load, interferon levels of IFNα and IFNγ were increased by 55% (p < 0.05) and 93%, respectively (p < 0.01), compared with those of healthy women, with a significant decrease in the content of IL-10 — by 85% (p < 0.01), IL-2 — by 53% (p < 0.05) and TNFα — by 56% (p < 0.05), the content of IL-1β was increased only by 8% (p > 0.05). When analyzing cytokine levels in patients with an increased viral load, IFNα was increased by 48% (p < 0.05) and IFNγ — by 62% (p < 0.05), as well as IL-1β — by 59% (p < 0.05), and TNFα — by 37% (p < 0.05), compared to healthy women, with a significant decrease in IL-10 and IL-2 — by 53% and 56%, respectively (p < 0.05). The increase in the concentration of TNFα and IFNγ with an increased viral load was slightly lower. In patients with a significant viral load, interferons IFNα and IFNγ were increased by 35% and 40%, accordingly (p < 0.05), IL-1β — by 17.9% (p < 0.05) and IL-10 — by 14.1% against the background of a slight decrease in the content of TNFα — by 14.5% (p >0.05) and a highly significant 2.26-fold decrease in IL-2 — (p < 0.05), which play an important role in the regulation of the Th1 immune response. After the treatment, in patients of the main group (complex 1) and a comparison group (complex 2) with no significant differences, the positive dynamics was observed, manifested in lowering the initially increased concentrations of TNFα and IFNγ, IL-1β and IL-10 approaching the level of healthy individuals; in the control group, the decrease of the initially increased IL-2 and TNFα was noted, and, although there was a positive dynamics of all the studied indicators, it was less pronounced. Conclusion. The obtained data indicate a pronounced immunocorrective effect of the combined use of blue monochromatic polarized incoherent light on the projection of the carotid arteries and polychromatic visible and infrared polarized light on the cervix in combination with Imiquimod 5% cream for external use in patients with chronic cervicitis associated with papillomavirus infection, which is confirmed by an improvement in the cytokine profile.

scholarly journals PENTOSAN POLYSULPHATE INFLUENCEON THE COURSE OF CHRONICKIDNEYDISEASE ST'. II - IV

2015 ◽  
pp. 10-16
Author(s):  
O. Dudari ◽  
M. Shifrisi ◽  
V.Ye. Driyanska ◽  
V.F. Krot ◽  
O.M. Loboda ◽  
...  
Keyword(s):  
Inflammatory Cytokines ◽  
Standard Therapy ◽  
Comparison Group ◽  
Lipid Lowering ◽  
Hypolipidemic Effect ◽  
Vascular Endothelial ◽  
Before And After ◽  
Pentosan Polysulphate ◽  
Group 2 ◽  
Endothelial Growth Factor

The aim is to determine the effect of the drug pentosan polysulphate at the rate of disease progression in patients with CKD II - IVst., to confirmation of lipid - lowering action and setting of the drug on indicators of chronic inflammation. Materials and methods. Tests conducted in one center for 12 weeks. The study included 60patients with CKD II - IV st. Patients were divided into 2 groups: group 1 (basic) - 30patients in addition to standard therapy receiving study medication, pentosan polysulphate, group 2 - 30 patients received only standard therapy. The drug pentosan polysulphate was administered for 8 - weeks: 100 mg. a day intramuscularly or intravenously for 3 weeks, followed by oral administration of 50 mg two times a day. The survey studied the dynamics ofdaily proteinuria, GFR, lipids, indicators of tumor necrosis factor, IL - 18 and vascular endothelial growth factor (VEGF) before and after treatment (12 week observation). Results. It was found a significant decrease in total cholesterol and atherogenic ratio after 3 months of treatment in the study group, hypolipidemic effect is more significant than in the comparison group. The group used pentosan polysulphate proteinuria reduction was more pronounced, and was 65% against 38% in the comparison group. Pentosan polysulphate in the treatment ofCKDpatients in stages II - IV contributes to significant decrease in inflammatory cytokines (IL - 18 and TNF - a) in contrast to the comparison group. Conclusions. The use of pentosan polysulphate in the treatment of patients with CKD stages II - IV had positive effect on lipid metabolism. Purpose pentosan polysulphate patients with CKD stages II - IV contributes to a significant reduction of the daily proteinuria and eGFR improvement, reduces levels of inflammatory cytokines: IL - 18 and TNF - a.  

scholarly journals The state of lipid exchange, hemostasis, inflammatory reaction and potentials for their correction in indirect revascularization in patients with critical ischemia of lower extremities (a correlation statistical analysis)

2021 ◽  
Vol 25 (1) ◽  
pp. 27-35
Author(s):  
J. V. Kosayev ◽  
I. A. Khasanov ◽  
N. S. Abushov ◽  
G. T. Taghi-zade
Keyword(s):  
Lipid Metabolism ◽  
Inflammatory Reaction ◽  
Standard Therapy ◽  
Therapy Group ◽  
Cytokine Therapy ◽  
Standard Therapy Group ◽  
Critical Ischemia ◽  
Indirect Revascularization ◽  
Blood Irradiation ◽  
Laser Blood Irradiation

Aim: to study the state of lipid metabolism, hemostasis, inflammatory reaction and the potential for their correction after indirect revascularization in patients with distal steno-occlusion of arteries and critical ischemia of lower extremities (critical ILE).Material and methods. Changes in hemostasis and dynamics of its parameters during the complex surgical treatment in 131 patients with critical ILE and distal arterial stenoocclusion were analyzed. To achieve the targeted goals, patients were divided into the following groups: 34 patients had traditional care (control group); 32 patients had intravenous laser blood irradiation in combination with standard therapy (Group I); 32 patients had cytokine therapy with roncoleukin in combination with standard therapy (Group II); 33 patients had intravenous laser blood irradiation combined with cytokine therapy and standard therapy (Group III). Parameters of lipid metabolism were studied in dynamics (total cholesterol, very low density lipoproteins, high density lipoproteins, triglycerides); products of lipid peroxidation (malondialdehydes, conjugates, superoxide dismutase); inflammatory mediators (C-reactive protein, sialic acids, seromucoids, fibrinogen A, circulating immune complexes); hemostatic parameters (fibrinogen, fibrinolytic activity, fibrin degradation products, antithrombin III activity). Hemostatic indices were compared with identical parameters of 48 apparently healthy individuals (reference group).Results. On admission, patients with critical ILE and distal wall occlusion had sharp changes in their lipid metabolism, inflammatory reaction, and hemostasis. Conclusion. The inclusion of intravenous laser blood irradiation and cytokine therapy separately and in combination in a set of therapeutic measures led to the leveling of the studied homeostasis indicators. The best results were obtained in the group where patients had combined perioperative intravenous laser blood irradiation with cytokine therapy in indirect revascularization.

Аpplying of high-frequency monopolar diathermocoagulation in the treatment of chronic pulpitis

2020 ◽  
Vol 1 (12) ◽  
pp. 40-42
Author(s):  
F. Yu. Daurova ◽  
D. I. Tomaeva ◽  
S. V. Podkopaeva ◽  
Yu. A. Taptun
Keyword(s):  
Root Canal ◽  
High Frequency ◽  
Antibacterial Effect ◽  
Comparison Group ◽  
Poor Quality ◽  
Endodontic Treatment ◽  
Root Canals ◽  
The Third ◽  
Before And After

Relevance: the reason for the development of complications in endodontic treatment is poor-quality instrumental treatment root canals.Aims: a study of the animicrobial action and clinical efficacy of high-frequency monopolar diathermocoagulation in the treatment of chronic forms of pulpitis.Materials and methods: 102 patients with various chronic forms of pulpitis were divided into three groups of 34 patients each. In the first two groups, high-frequency monopolar diathermocoagulation was used in endodontic treatment in different modes. In the third group, endodontic treatment was carried out without the use of diathermocoagulation (comparison group). The root canal microflora in chronic pulpitis in vivo was studied twice-before and after diathermocoagulation.Results: it was established that high-frequency monopolar diathermocoagulation in the effect mode is 3, power is 4 (4.1 W) and effect is 4, power is 4 (5.4 W) with an exposure time of 3 seconds, it has a pronounced antibacterial effect on all presented pathogenic microflora obtained from the root canals of the teeth.

scholarly journals Gametocyte carriage after seasonal malaria chemoprevention in Plasmodium falciparum infected asymptomatic children

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Abdullahi Ahmad ◽  
Aurelia Prom ◽  
John Bradley ◽  
Mamadou Ndiath ◽  
Blessed Etoketim ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Comparison Group ◽  
Conditional Logistic Regression ◽  
Gametocyte Carriage ◽  
Asymptomatic Children ◽  
Seasonal Malaria Chemoprevention ◽  
Before And After ◽  
Chi Squared ◽  
Comparison Groups ◽  
To Receive

Abstract Background Treatment of clinical Plasmodium falciparum malaria with sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) is associated with increased post-treatment gametocyte carriage. The effect of seasonal malaria chemoprevention (SMC) with SP and AQ on gametocyte carriage was assessed in asymptomatic P. falciparum infected children. Methods The study was carried out in eastern Gambia. Asymptomatic P. falciparum malaria infected children aged 24–59 months old who were eligible to receive SMC (SMC group) and children 5–8 years that were not eligible to receive SMC (comparison group) were recruited. Gametocytaemia was determined by molecular methods before and after SMC administration. Gametocyte carriage between the groups was compared using the chi-squared test and within-person using conditional logistic regression. Results During the 2017 and 2018 malaria transmission seasons, 65 and 75 children were recruited in the SMC and comparison groups, respectively. Before SMC administration, gametocyte prevalence was 10.7% (7/65) in the SMC group and 13.3% (10/75) in the comparison group (p = 0.64). At day 13 (IQR 12, 13) after SMC administration, this was 9.4% (5/53) in children who received at least the first dose of SMC treatment and 12.7% (9/71) for those in the comparison group (p = 0.57). Similarly, there was no difference in prevalence of gametocytes between children that adhered to all 3-day doses of SMC treatment 15.6% (5/32) and those in the comparison group (p = 0.68). In the SMC group, within-group gametocyte carriage was similar before and after SMC administration in children that received at least the first dose of SMC treatment (OR 0.6, 95% CI 0.14–2.51; p = 0.48) and in those that adhered to all 3-day doses of SMC treatment (OR 1.0, 95% CI 0.20–4.95; p = 1.0). Conclusion In this study with relative low gametocyte prevalence prior to SMC treatment, no evidence was observed that SMC treatment increased gametocyte carriage in asymptomatic P. falciparum malaria infected children.

Children’s dermatology life quality index and family dermatology life quality index as criteria for the efficiency of physiorehabilitation of children with atopic dermatitis

2020 ◽  
pp. 43-49
Author(s):  
T. V. Koroleva ◽  
I. I. Ivanova ◽  
E. V. Filatova
Keyword(s):  
Atopic Dermatitis ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Life Quality ◽  
Polarized Light ◽  
Social Maladjustment ◽  
Life Quality Index ◽  
Laser Blood Irradiation ◽  
Intensity Laser

Social maladjustment of children with atopic dermatitis, an increase in the number of cases of disability in pediatric practice, violation of intra-familial relations, rise in the level of anxiety of parents, in particular, of mothers, are closely associated with the formation of protracted recurrent forms. Educational programs for parents, traditional conservative treatment and hydrotherapy in combination with polychromatic polarized light and low-intensity laser blood irradiation significantly improve the quality of life of patients and their families, according to the corresponding indices.

scholarly journals Impact of mindfulness for people with arthritis

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Sinead Brophy ◽  
Roxanne Cooksey ◽  
Jonathan Kennedy ◽  
Helen Davies
Keyword(s):  
Cohort Study ◽  
Stress Reduction ◽  
Data Linkage ◽  
Comparison Group ◽  
Effectiveness Analysis ◽  
Before And After ◽  
Number Of Visits ◽  
Mindfulness Based Stress Reduction ◽  
Gp Visits ◽  
The Impact

ABSTRACTObjectiveTo examine the impact of mindfulness-based stress reduction (MBSR) for people with ankylosing spondylitis (AS). Methods193 People with AS were invited to take part in an MBSR 8 week course. The data linkage component of this study examined number of visits to the general practitioner before and after the course in participants and non-participants of the course (500 people taking part in a cohort study but not invited to the course). ResultsOf 193 people invited, 43 (22%) consented and took part in the course, GP records were available for 41 (95%) of MBSR participants and 457 (91%) of the 500 comparison group. There was a mean of 7.6 (median 3) visits to the GP in the 12 month period before the course for those undertaking MBSR and 4.6 (median 0) visits in the 12 month period after the course. This compared with 5.5 (median 0) visits (12 months before a random date) and 4.1 (median 0) visits (12 months after a random date) in the comparison group. Using Wilcoxon rank-sum (Mann-Whitney) test showed a significant reduction in GP visits in the MBSR group after the course compared to the comparison group. ConclusionsThose who chose to attend an MBSR course had a higher number of visits to the GP before attending the course, than the comparison group. However, after attending the stress reduction course the number of visits to the GP reduced to levels equivalent to the comparison group. This study suggests that mindfulness based stress reduction could be effective in reducing the number of visits to the GP for people with arthritis who regularly see their GP. The findings from this study suggest a full RCT and cost effectiveness analysis is warranted.

scholarly journals TEFL and COVID-19: use of digital materials and their impact on efl learners' speaking accuracy and fluency

2021 ◽  
Vol 7 (3B) ◽  
pp. 729-741
Author(s):  
Mohammad Hossein Besharati ◽  
Golnar Mazdayasna ◽  
Ali Akbar Jabbari
Keyword(s):  
Experimental Design ◽  
Foreign Language ◽  
Digital Storytelling ◽  
Comparison Group ◽  
Language Skills ◽  
Placement Test ◽  
Promising Technique ◽  
Efl Learners ◽  
Before And After ◽  
Quasi Experimental

Digital storytelling has been around in foreign language contexts for at least two decades and showed to be a promising technique for teaching different language skills. This study aimed at investigating the effect of using two types of digital storytelling, i.e. asynchronous and synchronous digital storytelling, on the EFL learners' speaking performance in terms of accuracy and fluency. To this end, a quasi-experimental design with an experimental and a comparison group was devised. Sixty-five intermediate EFL learners were conveniently selected based on their scores on Oxford Placement Test. The speaking module of Preliminary English Test (PET) was used to measure the participants' speaking accuracy and fluency before and after the intervention. The results of the study indicated that both groups made a significant improvement after the course. Nevertheless, the asynchronous digital storytelling group outperformed the synchronous one after the intervention.

scholarly journals Changes on Serum Troponin T Level before and after Taking Standard Therapy Medication in Heart Failure Patients

2020 ◽  
Vol 56 (1) ◽  
pp. 4
Author(s):  
Yen Yen Ari Indrawijaya ◽  
Suharjono Suharjono ◽  
Muhammad Aminuddin ◽  
Endang Retnowati ◽  
Gilang Mauladi Rahman
Keyword(s):  
Heart Failure ◽  
Cardiac Troponin ◽  
Standard Therapy ◽  
Troponin T ◽  
Severe Heart Failure ◽  
Myocardial Necrosis ◽  
Myocardial Damage ◽  
Symptom Improvement ◽  
Before And After ◽  
Difference Test

Patients with advanced heart failure (NYHA FC III and IV heart failure) had positive cardiac troponin levels in previous cohort studies. In heart failure, cardiac troponin T (cTnT) is a biomarker that is sensitive to myocardial damage, especially myocardial necrosis. However, there is still little information regarding changes in cTnT levels during standard therapy. This prospective observational study is aimed at evaluating changes in cTnT levels before and after the administration of standard therapy and evaluating symptom improvement before and after the administration of standard therapy in patients with severe heart failure. Measurement of cTnT levels and symptom improvement parameters before treatment was carried out on the first day of the inpatient and measurement after therapy was carried out on the last day of the inpatient. Sampling was done by consecutive sampling and found 30 patients in the inpatient room of the SMF Cardiovascular Disease, Dr. Soetomo Hospital, Surabaya during the months of May-July 2017. The results of the study obtained the average cTnT levels before therapy 33.48 + 31.88 pg/ml and the average cTnT levels after therapy 46.32 + 52.68 pg/ml. Based on the statistical difference test with the Wilcoxon sign-ranked test, there was no significant change in cTnT levels (p = 0.318). On the parameter of clinical symptom improvement, there was a significant decrease in pulse, respiratory rate, blood pressure, and mean arterial pressure before and after administration of therapy (p <0.05). There was no change in troponin T levels before and after the administration of therapy meant there was no worsening of myocardial necrosis.

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