Arthroscopic features of primary and concomitant flexor enthesopathy in the canine elbow

2013 ◽  
Vol 26 (05) ◽  
pp. 340-347 ◽  
Author(s):  
Y. Samoy ◽  
E. Coppieters ◽  
L. Mosselmans ◽  
B. Van Ryssen ◽  
E. de Bakker
Keyword(s):  
Clinical Significance ◽  
Correct Diagnosis ◽  
Diagnostic Techniques ◽  
Coronoid Process ◽  
Sensitive Detection ◽  
Pathological Changes ◽  
Elbow Dysplasia ◽  
Arthroscopic Examination

SummaryObjectives: To investigate the possibilities and limitations of arthroscopy to detect flexor enthesopathy in dogs and to distinguish the primary from the concomitant form.Materials and methods: Fifty dogs (n = 94 elbow joints) were prospectively studied: dogs with primary flexor enthesopathy (n = 29), concomitant flexor enthesopathy (n = 36), elbow dysplasia (n = 18), and normal elbow joints (n = 11). All dogs underwent an arthroscopic examination of one or both elbow joints. Presence or absence of arthroscopic characteristics of flexor enthesopathy and of other elbow disorders were recorded.Results: With arthroscopy, several pathological changes of the enthesis were observed in 100% of the joints of both flexor enthesopathy groups, but also in 72% of the joints with elbow dysplasia and 25% of the normal joints. No clear differences were seen between both flexor enthesopathy groups.Clinical significance: Arthroscopy allows a sensitive detection of flexor enthesopathy characteristics, although it is not very specific as these characteristics may also be found in joints without flexor enthesopathy. The similar aspect of both forms of flexor enthesopathy and the presence of mild irregularities at the medial coronoid process in joints with primary flexor enthesopathy impedes the arthroscopic differentiation between primary and concomitant forms, requiring additional diagnostic techniques to ensure a correct diagnosis.

scholarly journals Elbow lameness in dogs of six years and older

2010 ◽  
Vol 23 (01) ◽  
pp. 43-50 ◽  
Author(s):  
A. L. R. Bergenhuyzen ◽  
I. Gielen ◽  
H. van Bree ◽  
L. Duchateau ◽  
B. Van Ryssen ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Retrospective Study ◽  
Clinical Significance ◽  
Coronoid Process ◽  
Medial Compartment ◽  
Elbow Arthroscopy ◽  
Arthroscopic Findings ◽  
High Incidence ◽  
Arthroscopic Examination ◽  
Humeral Condyle

Summary Objectives: To report on the frequency and distribution of lesions of the medial coronoid process in dogs of six years of age and older, and to describe the arthroscopic findings in the affected joints. To compare those lesions seen in ‘old’ dogs with those seen in ‘young’ dogs between the ages of five and 18 months. Methods: A retrospective study of dogs six-years-old and older admitted for elbow lameness and subsequent elbow arthroscopy. The dogs were divided into groups according to the lesions of the medial coronoid process diagnosed during arthroscopic examination and computed tomography (CT). The radio-graphic degree of osteoarthritis (OA) and arthroscopically diagnosed lesions on the medial humeral condyle are described. Results: In 51 ‘old’ dogs, five types of lesions could be identified on arthroscopy and CT: chondromalacia-like lesions (2%), fissures (27.5%), non-displaced fragments (12%), displaced fragments (27.5%), and erosions within the medial compartment without fragmentation (31%). A significantly different distribution of lesions was seen in ‘young’ dogs: fissures (23%), non-displaced fragments (45%), displaced fragments (29%), and erosions within the medial compartment without fragmentation (3%). No difference in radio-graphic degree of OA was seen between the two groups. Clinical significance: This study demonstrates the relatively high incidence of medial coronoid disease in dogs older than six years of age, and it highlights one particular problem in ‘old’ dogs: the complete erosion of the medial compartment.

scholarly journals Type Va extrahepatic bile duct duplication: a case report

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Bharat Mani Banjade ◽  
Ashish Rajbhandari ◽  
Rabin Koirala ◽  
Tuhin Shah ◽  
Chitra Lal Bhattachan
Keyword(s):  
Case Report ◽  
Bile Duct ◽  
Extrahepatic Bile Duct ◽  
Correct Diagnosis ◽  
Diagnostic Techniques ◽  
Case Presentation ◽  
Double Common Bile Duct ◽  
Unusual Variant ◽  
Rural Nepal ◽  
Calculous Cholecystitis

Abstract Background Extrahepatic bile duct duplication is an extremely rare congenital anomaly in which two common bile ducts exist. There are five different types of this anomaly and we present an unusual variant of duplication of an extrahepatic biliary system of type Va variety. Case presentation This case report describes a 63-year-old women from rural Nepal who presented with type Va of duplicated extrahepatic bile duct, with chronic calculous cholecystitis and choledocholithiasis. She was managed with cholecystectomy with hepatic ductoplasty and hepaticojejunostomy. Conclusion A rare case of double common bile duct (type Va) complicated by choledocholithiasis, cholangitis, and chronic cholecystitis is reported here. Rare cases are sometimes overlooked by modern diagnostic techniques. Correct diagnosis helps appropriate surgical intervention.

DIFFERENTIAL DIAGNOSIS OF DISEASES OF THE MUCOSA OF THE ORAL CAVITY

2021 ◽  
Vol Special issue (2) ◽  
pp. 45-49
Author(s):  
Odinakhon Umarova ◽  
◽  
Mahpirathon Rasulova
Keyword(s):  
Differential Diagnosis ◽  
Oral Cavity ◽  
Mucous Membrane ◽  
Laboratory Tests ◽  
Correct Diagnosis ◽  
Laboratory Research ◽  
Pathological Changes ◽  
Oral Mucous Membrane ◽  
Diagnosis Of Diseases ◽  
Clinical Cases

Variants of pathological changes related to the group of white lesions: multiform erythema, flat lichen, candidiasis glossitis at the stage of formation of white foci. In this paper we consider the differential diagnosis of multiform erythema, planar lichen, candidiasis glossitis in the presence of signs of white plaque. Clarification of the diagnosis is based on a thorough examination and additional (including laboratory) research methods. Analysis of the results of observation of clinical cases of oral mucosa diseases to differentiate existing foci for correct diagnosis and subsequent treatment.The analysis of clinical cases of diseases of the oral mucous membrane indicates the similarity of their elements of destruction and manifestations of other symptoms, which greatly complicates the diagnostic search. A thorough survey, inspection, consultations of general specialists and additional laboratory tests allow to successfully solve the tasks

scholarly journals Co-infection by Tritrichomonas foetus and Pentatrichomonas hominis in asymptomatic cats

2015 ◽  
Vol 35 (12) ◽  
pp. 980-988 ◽  
Author(s):  
Caroline Spitz dos Santos ◽  
Vera Lúcia Teixeira de Jesus ◽  
Douglas McIntosh ◽  
Bruno Pereira Berto ◽  
Carlos Wilson Gomes Lopes
Keyword(s):  
Molecular Analysis ◽  
Morphological Analysis ◽  
Correct Diagnosis ◽  
Diagnostic Techniques ◽  
Tritrichomonas Foetus ◽  
Specific Primers ◽  
Transmission Electron ◽  
Appropriate Treatment ◽  
Simultaneous Infection ◽  
Pentatrichomonas Hominis

Abstract: Tritrichomonas foetus, a parasite well known for its significance as a venereally transmitted pathogen in cattle, has been identified as a cause of chronic large bowel diarrhea in domestic cats in many countries of the world. In Brazil, several studies on the diagnosis of bovine trichomoniasis have been performed, but until now, no study was made regarding feline trichomoniasis. Thus, this is the first study to report the occurrence of T. foetus and Pentatrichomonas hominis in cats using morphological and molecular analysis. Feces from 77 cats were examined, four of which (5.2%) were positive for the presence of parabasalids. Morphological analysis of stained smears revealed piriform trophozoites showing the three anterior flagella, elongated nucleus and axostyle ending abruptly in fillet, characteristic of T. foetus. In scanning and transmission electron microscopy, identification characters similar to those previously reported for T. foetus were observed. The cultures containing trophozoites were submitted for molecular analysis, which resulted positive for T. foetus DNA using specific primers (TFR3 and TFR4), and all samples were positive and subjected to sequencing in which they showed 99.7-100% similarity with another isolate sequencing of T. foetus (JX960422). Although no trophozoite with consistent morphology of P. hominis has been visualized in the samples, differential diagnosis was performed using specific primers for P. hominis (TH3 and TH5) amplicon. In three of the four samples (3.89%) sequencing revealed 100% similarity when compared with another sequence of P. hominis deposited in Genbank (KC623939). Therefore, the present study revealed through the diagnostic techniques employed the simultaneous infection by T. foetus and P. hominis in the feces of cats. However, it was necessary to use more than one technique for the diagnosis of the co-infection. These results demonstrate the importance of a correct diagnosis to allow an appropriate treatment by the veterinarian.

scholarly journals Promising Colorectal Cancer Biomarkers for Precision Prevention and Therapy

Cancers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1932 ◽  
Author(s):  
Mimmo Turano ◽  
Paolo Delrio ◽  
Daniela Rega ◽  
Francesca Cammarota ◽  
Alessia Polverino ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Early Detection ◽  
Correct Diagnosis ◽  
Cancer Biomarkers ◽  
Diagnostic Techniques ◽  
Liquid Biopsies ◽  
Tumor Tissues ◽  
Precision Therapy ◽  
Clinical Strategy

Colorectal cancer (CRC) has been ranked as the third most prevalent cancer worldwide. Indeed, it represents 10.2% of all cancer cases. It is also the second most common cause of cancer mortality, and accounted for about 9.2% of all cancer deaths in 2018. Early detection together with a correct diagnosis and staging remains the most effective clinical strategy in terms of disease recovery. Thanks to advances in diagnostic techniques, and improvements of surgical adjuvant and palliative therapies, the mortality rate of CRC has decreased by more than 20% in the last decade. Cancer biomarkers for the early detection of CRC, its management, treatment and follow-up have contributed to the decrease in CRC mortality. Herein, we provide an overview of molecular biomarkers from tumor tissues and liquid biopsies that are approved for use in the CRC clinical setting for early detection, follow-up, and precision therapy, and of biomarkers that have not yet been officially validated and are, nowadays, under investigation.

scholarly journals Elbow dysplasia and lesions of the medial coronoid process: correlation between tomographic and arthroscopic findings in thirty cases

2008 ◽  
Vol 32 (S1) ◽  
pp. 247-249
Author(s):  
A. F. Botazzoli ◽  
F. Ferraresi ◽  
O. Travetti ◽  
F. M. Martini ◽  
C. M. Mortellaro ◽  
...  
Keyword(s):  
Coronoid Process ◽  
Elbow Dysplasia ◽  
Arthroscopic Findings

scholarly journals EVALUATION OF ESOPHAGEAL ACHALASIA: FROM SYMPTOMS TO THE CHICAGO CLASSIFICATION

2018 ◽  
Vol 31 (2) ◽  
Author(s):  
Rafael Melillo LAURINO-NETO ◽  
Fernando HERBELLA ◽  
Francisco SCHLOTTMANN ◽  
Marco PATTI
Keyword(s):  
Clinical Features ◽  
Digestive System ◽  
Correct Diagnosis ◽  
Esophageal Achalasia ◽  
Diagnostic Techniques ◽  
Diagnostic Methods ◽  
Esophageal Disease ◽  
Barium Swallow ◽  
High Resolution Manometry ◽  
Therapeutic Decision Making

ABSTRACT Introduction: The diagnosis of achalasia may be suggested by clinical features but a complete work-up is required not only to confirm the diagnosis but also to grade the disease by severity or clinical subtype. Objective: To review the current evaluation of esophageal achalasia and its correct comprehension. Method: The literature review was based on papers published on Medline/Pubmed, SciELO and Lilacs, crossing the following headings: “esophageal achalasia”; “deglutition disorders”; “diagnostic techniques”, “digestive system”; “endoscopy, digestive system”; “manometry”. Results: The diagnosis of achalasia is suggested by clinical features but is not sufficient to distinguish this from other esophageal disease. It must be confirmed by further diagnostic tests, such as esophagogastroduodenoscopy, barium swallow and manometry. Recent advances in diagnostic methods, including high resolution manometry might even help predicting outcome or selected more appropriate procedures to treat the disease. Conclusion: A detailed and systematic study of achalasia patients allows not only a correct diagnosis but also contributes to therapeutic decision making and prognosis.

scholarly journals Medial compartment disease in a young Large Munsterlander

2012 ◽  
Vol 81 (2) ◽  
pp. 88-92
Author(s):  
E. Coppieters ◽  
Y. Samoy ◽  
P. Pey ◽  
T. Waelbers ◽  
B. Van Ryssen
Keyword(s):  
Elbow Joint ◽  
Substantial Improvement ◽  
Additional Treatment ◽  
Coronoid Process ◽  
Medial Compartment ◽  
Radiographic Examination ◽  
Arthroscopic Examination ◽  
The Right ◽  
Humeral Condyle ◽  
Strong Suspicion

Medial compartment disease (MCD) is a recently recognized elbow disorder in dogs and refers to extensive cartilage erosions of the medial compartment of the elbow joint. This report describes a case of MCD in a 10- month-old Large Munsterlander that was presented with right frontleg lameness. Based on signalement, history and radiographic examination, there was a strong suspicion of a fragmented coronoid process (FCP) of the right elbow. However, arthroscopic examination revealed extensive cartilage erosions of the medial part of the humeral condyle and the medial coronoid process in addition to a small coronoid fragment (FCP) and a small OCD-like lesion. After the arthroscopic treatment, the dog did not improve. Neither did additional treatment with autologous conditioned plasma (Arthrex ACP®) lead to a substantial improvement. Finally, the dog was euthanized because of persistent lameness.

scholarly journals New Resources for the Specific and Sensitive Detection of the Emerging Tomato Brown Rugose Fruit Virus

Viruses ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1680
Author(s):  
Joan Miquel Bernabé-Orts ◽  
Covadonga Torre ◽  
Eduardo Méndez-López ◽  
Yolanda Hernando ◽  
Miguel A. Aranda
Keyword(s):  
Internal Control ◽  
Plant Protection ◽  
Genetic Resistance ◽  
Diagnostic Techniques ◽  
Plant Viruses ◽  
Elisa Test ◽  
Cross Reactivity ◽  
Sensitive Detection ◽  
Enzyme Linked Immunosorbent Assay ◽  
Effective Prevention

Plant viruses can evolve towards new pathogenic entities that may eventually cause outbreaks and become epidemics or even pandemics. Seven years ago, tomato brown rugose fruit virus (ToBRFV) emerged, overcoming the genetic resistance that had been employed for more than sixty years against tobamoviruses in tomato. Since then, ToBRFV has spread worldwide, producing significant losses in tomato crops. While new resistances are deployed, the only means of control is the implementation of effective prevention and eradication strategies. For this purpose, in this work, we have designed, assessed, and compared an array of tests for the specific and sensitive detection of the ToBRFV in leaf samples. First, two monoclonal antibodies were generated against a singular peptide of the ToBRFV coat protein; antibodies were utilized to devise a double-antibody-sandwich enzyme-linked immunosorbent assay (DAS-ELISA) test that sensitively detects this virus and has no cross-reactivity with other related tobamoviruses. Second, a real-time quantitative PCR (RT-qPCR) test targeting the RNA-dependent replicase open reading frame (ORF) was designed, and its performance and specificity validated in comparison with the CaTa28 and CSP1325 tests recommended by plant protection authorities in Europe. Third, in line with the tendency to use field-deployable diagnostic techniques, we developed and tested two sets of loop-mediated isothermal amplification (LAMP) primers to double-check the detection of the movement protein ORF of ToBRFV, and one set that works as an internal control. Finally, we compared all of these methods by employing a collection of samples with different ToBRFV loads to evaluate the overall performance of each test.

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