Factors Related to Case Of Coronavirus Disease 2019 (Covid-19)

As of March 24, 2021, in Indonesia there were 1,482,559 confirmed cases. East Java province occupies the third highest cases after DKI Jakarta and West Java Province. Gresik Regency still has many additional confirmed cases. Based on strategic guidelines, prevention efforts are needed, namely the 5M movement, knowledge and attitudes related to prevention efforts that are very important so as not to cause an increase in the number of cases. The purpose of this research was to determine the factors associated with the incidence of Covid-19. This type of research is quantitative research with a case control study design. The results of the study were that 69 respondents (74.2%) had a history of negative status and 24 people (25.8%) had a positive status. Factor related to the history of Covid-19 incidence is enabling factors (affordability of health facilities) with p value = 0.003. Analysis of the close relation between the two variables obtained Odd Ratio = 0.180 (95% CI: 0.060-0.538), and there was no relationship between predisposing factors and reinforcing factors with the incidence of Covid-19 history. ABSTRAK Terhitung sampai tanggal 24 Maret 2021, di Indonesia tercatat 1,482,559 terkonfirmasi. Provinsi jawa timur menduduki kasus tertinggi ketiga setelah DKI Jakarta dan Provinsi Jawa Barat. Kabupaten Gresik masih banyak penambahan confrim kasus. Berdasarkan panduan strategis diperlukan upaya pencegahan, yaitu gerakan 5M, serta pengetahuan dan sikap terkait upaya pencegahan adalah hal yang sangat penting agar tidak menimbulkan peningkatan jumlah kasus. Tujuan penelitian ini untuk mengetahui faktor–faktor yang berhubungan dengan kejadian riwayat Covid-19. Jenis penelitian ini adalah penelitian kuantitatif dengan desain studi case control. Hasil penelitian adalah responden memiliki riwayat status negatif sebanyak 69 orang (74.2%) dan yang memiliki status positif sebanyak 24 orang (25.8%). Faktor yang berhubungan dengan riwayat kejadian Covid-19 adalah faktor pemungkin (keterjangkauan fasilitas kesehatan) dengan nilai p = 0,003. Analisis keeratan hubungan dua variabel diperoleh Odd Ratio = 0,180 (95% CI : 0,060-0,538), serta tidak ada hubungan antara faktor predisposisi dan faktor penguat dengan kejadian riwayat Covid-19.

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Determinants of Severe Acute Malnutrition among Children age 6-59 Months Old in Two Public Hospitals, North West Ethiopia: a Case Control Study

10.1101/664516 ◽

2019 ◽

Author(s):

Adonia Damtew Nebro ◽

Degnet Teferi Asres ◽

Reddy PCJ Prasad

Keyword(s):

Exclusive Breastfeeding ◽

Case Control Study ◽

Severe Acute Malnutrition ◽

Case Control ◽

Hand Washing ◽

Acute Malnutrition ◽

P Value ◽

Monthly Income ◽

History Of ◽

Control Study

AbstractIntroductionGlobally sever acute malnutrition affects 16.4 million under five children and more than one quarter of those children live in Africa. In Ethiopia, about 3% of children are severely wasted and continues to be persistent over the past 15 years. To implement an effective intervention, it is essential to identify predictors predispose to it. This study therefore, aimed to identify determinants of severe acute malnutrition among under five children in selected public health facilities, Northwest Ethiopia.MethodsInstitution based; age matched case control study was conducted on 104 cases and 208 controls. Bivariate and multivariate analyses were done using conditional logistic regression to identify predictors. Variables having P-value ≤ 0.2 during binary analysis were entered into multivariate analysis. P value < 0.05 was considered as statistically significant.ResultsChildren from households of large family size(AOR=2.7, 95% CI: 1.06 – 6.9), having monthly income less than 1500 birr (AOR = 5.17, 95% CI: 1.7-15.3), which are food insecure (AOR = 2.9, 95% CI:1.17-7.28)), which didn’t receive any nutrition information (AOR= 3.47,95% CI: 1.14 - 7.10), didn’t practice exclusive breastfeeding (AOR = 2.69, 95% CI: 1.18 - 6.10), and practice infrequent hand washing (AOR= 7.6 95% CI:2.44-23.6) as well as children who had history of diarrhea two weeks prior to the survey (AOR 3.2, 95%CI:1.4-7.2) were more likely to suffer from severe acute malnutrition.ConclusionFamily size, monthly income, food security status, exclusive breastfeeding practice, access to information on child feeding, hand washing practice and history of diarrhea were identified to be predictors of severe acute malnutrition. Due emphasis should be given to promoting family planning, improve household livelihoods and food security, strength awareness creation on exclusive breastfeeding and frequent hand washing practices as well as prevention of diarrhea.

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Birth Month And Prevalence Of Atopic Dermatitis In Children Under 3 Years In Antananarivo, Madagascar

10.21203/rs.2.23109/v1 ◽

2020 ◽

Author(s):

Fandresena Arilala Sendrasoa ◽

Volatantely Ratovonjanahary ◽

Mendrika Fifaliana Rakotoarisaona ◽

Malalaniaina Andrianarison ◽

Onivola Raharolahy ◽

...

Keyword(s):

Case Control Study ◽

Case Control ◽

University Hospital ◽

P Value ◽

Month Of Birth ◽

Birth Month ◽

History Of ◽

The University ◽

The Relationship ◽

Control Study

Abstract BACKGROUND: Several studies have been done to evaluate the relationship between month of birth and atopic diseases but the results are contradictory. So, we aim to evaluate the correlation between the month of birth and the prevalence of AD in Malagasy children less than 3 years.METHODS: A case-control study was conducted based on patients’ data of the department of Dermatology in the University Hospital Joseph Raseta Befelatanana (UH/JRB) Antananarivo. It included 354 children less than 3 years seen in this department between January 2010 and December 2018. For each AD patient, two age and sex-matched controls without a history of AD were selected from the same period.RESULTS: This study included 118 AD cases and 236 non-AD controls. Our case-control study found that there are no statistically significant correlation between birth month and risk of AD in Malagasy children < 3 years. However, the fewest children with AD were born in February (17.86%, OR: 0.40, CI 95%: 0.11-1.14), and the most were born in August (45.16%, OR: 1,73; CI 95%: 0,75-3,88). Asthma, allergic rhinitis and allergic conjunctivitis were significantly correlated with AD in our patients.CONCLUSION: Our case-control study found that there are no statistically significant correlation between birth month and risk of AD in children < 3 years. However, the high frequency of AD in children born in August (dry season) compared to non-AD controls was not negligible (p-value =0,05 and X 2 3,27).

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Determinants of neonatal near misses among neonates admitted to Guji and Borena zones selected public hospitals, Southern Ethiopia, 2021: A facility based unmatched case control study design

PLOS Global Public Health ◽

10.1371/journal.pgph.0000168 ◽

2022 ◽

Vol 2 (1) ◽

pp. e0000168

Author(s):

Anteneh Fikrie ◽

Elias Amaje ◽

Amana Jilo Bonkiye ◽

Wako Golicha Wako ◽

Alqeer Aliyo ◽

...

Keyword(s):

Birth Interval ◽

Neonatal Death ◽

Case Control Study ◽

Case Control ◽

Public Hospitals ◽

Southern Ethiopia ◽

P Value ◽

Near Misses ◽

History Of ◽

Control Study

There is little available evidence that quantifies the determinats of NNM in Ethiopia despite an increasing magnitude of neonatal mortality. Therefore, this study was designed to provide concrte evidence about the determinats of NNMS among neonates admitted to Guji and Borena Zones Public Hospitals, Southern Ethiopia, 2021. A facility based unmatched case control study design was conducted on 402 (134 cases and 268 controls) selected neonates admitted to Bule Hora, Adola and Yabelo General Hospitals from February 1-March 31, 2021. Cases were consecutively selected. Whereas for each case, two controls were selected by systematic random sampling technique. The data collection included a pretested and structured face-to-face interviewer administered questionnaire with a supplementation of maternal and neonatal medical records with checklists. Then the data were coded and entered in to Epi data version 3.1 and then exported to the Statistical Package for Social Science IBM version 25 for analysis. The descriptive statistics run and the results of the data were presented using frequencies, and tables. Bivariable and multi variable logistic regression was used for the analsysis of the data. Finally, Adjusted Odds Ratio together with 95% Confidence Intervals and p value <0.05 was used to declare the significance of all statistic. A total of 134 cases (neonatal near misses) and 268 controls (normal neonate) were participated in this study to make a response rate of 100% for both cases, and controls. In this study rural residence (AOR = 0.51, 95% CI: 0.27, 0.96), previous history of neonatal death (AOR = 4.85, 95%CI: 2.24,10.49), birth interval ≤ 2 years (AOR = 1.83, 95% CI: 1.04, 3.11) and history of abortion (both induced and miscarriage) (AOR = 1.97, 95%CI: 1.17, 3.31) were found to be statistically significant at a p-value of <0.05. History of prior abortion history of prior neonatal death and short birth interval (≤ 2 years) were identified to be the determinats of NNMs. High quality antenatal and intrapartum continuum of care should be provided for women and neonates. Additionally, contraceptive utilization should be encouraged for a women to space the births of their children.

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Analisis Faktor Ibu yang Pernah Bersalin Nomal Mengalami Risiko Bedah CCaesarea

Jurnal Maternitas Kebidanan ◽

10.34012/jumkep.v4i2.695 ◽

2019 ◽

Vol 4 (2) ◽

pp. 1

Author(s):

Siti maisyaroh Fitri Siregar

Keyword(s):

Case Control Study ◽

Sampling Technique ◽

Case Control ◽

Bivariate Analysis ◽

P Value ◽

Chi Square ◽

Chi Square Test ◽

History Of ◽

Dominant Influence ◽

Control Study

ABSTRACT The objective of the research was to analyze the risk factors of women with the history of normal childbirth had delivery by section caesarea. The research used observational analytic method with case-control study design. The samples consisted of 42 cases and 42 controls, taken by using consecutive sampling technique. Dependent variable was childbirth with CS and independent variables were parity, accompanied illness, and reference. The gathered data were analyzed by using univatriate analysis, bivariate analysis with chi square test, and multivatriate analysis at α = 0.05. The result of the research from multivariate analysis showed that the variables which had significant influence on childbirth with SC were parity (p = 0.006; OR = 5.801 95% CI = 1.642-19.110),accompanied illness (p = 0.03; OR = 6.382 95% CI = 1.198-33.992), and reference (p = 0.003; OR = 6.350 95% CI = 1.874-21.522). The variable which had the most dominant influence childbirth with CS was accompanied illness. p-value = 97% which indicated that childbirth women with the parity > 2 had accompanied illness and the reference to the hospital had the possibility to give birth with CS of 97%. It is recommended to do family planning programme, and prevent the illness during pregnant, apply ANC according to the standard, and make sure that the childbirth is safe from Period I to Period III. Keywords: Risk Factor, Caesarea, Case-Control

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Association of Obesity with Peripheral Vascular Disease- A Case-control Study

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2021/47899.14521 ◽

2021 ◽

Author(s):

Sadhasiva Bhavadeep Kumar Reddy ◽

Kothareddy Dileep ◽

Raja Reddy Ramya ◽

Shripad B Deshpande

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Vascular Disease ◽

Central Obesity ◽

Case Control Study ◽

Case Control ◽

P Value ◽

Peripheral Vascular ◽

History Of ◽

Control Study

Introduction: Peripheral Vascular Disease (PVD) is an important public health problem, due to its insidious course and the associated co-morbidities. Obesity has been implicated as one of the risk factor besides others. However, the reports on obesity are not consistent. Aim: To assess the association between central obesity and PVD along with other risk factors and the present study is undertaken to examine the correlation of central obesity as a risk factor for PVD. Further, the association between other risk factors and PVD was also ascertained. Materials and Methods: A total of 124 subjects were recruited in this case-control study. Ankle Brachial Index (ABI) was measured using peripheral Doppler studies. Patients with ABI <0.9 were taken as cases and with ABI >0.9 were taken as controls. Blood pressure was measured in the sitting position and the authors obtained anthropometric and demographic data. Chi-square test was used as the test of significance and p-value <0.05 to be considered as level of significance. Results: Of the total 124 participants in the study, 62 participants were the cases and 62 participants were controls. Body Mass Index (BMI) was higher in cases with PVD but Waist Circumference (WC) and hip circumference were significantly lower (p-value=0.003 and <0.001 respectively) and Waist-Hip Ratio (WHR) did not show any significant difference between cases and controls. Thus, fat mass is located elsewhere in these individuals, possibly it may be accumulated in the extremities. Other risk factors like history of smoking, history of alcoholism and history of diabetes mellitus had a positively significant association with PVD with p-values <0.001, 0.023 and <0.001 respectively. Conclusion: The results obtained from this data suggests that PVD is not associated with central obesity, instead it provides evidence that PVD correlates with peripheral fat mass. Subsequent studies separating central and peripheral obesity are required to get more clarity on the relationship between obesity and PVD.

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Risk Factors Among Breast Cancer Patients Being Treated in Tertiary Level Hospital of Nepal: A Case Control Study

Journal of Institute of Medicine ◽

10.3126/jiom.v42i1.37459 ◽

2020 ◽

Vol 42 (1) ◽

pp. 79

Author(s):

Asmita Rana ◽

Anup Ghimire ◽

Ram B Sah ◽

Prajjwal Pyakurel ◽

Nirmal P Shah

Keyword(s):

Breast Cancer ◽

Risk Factors ◽

Benign Breast Disease ◽

Case Control Study ◽

Breast Disease ◽

Case Control ◽

P Value ◽

Increased Risk ◽

History Of ◽

Control Study

Introduction Breast cancer is the leading cause of cancer death among females worldwide. Its incidence is on the rise in Nepal. However, the risk factors have not been studied in context of Nepal. The aim of this study is to identify and quantify the association of various risk factors with breast cancer in Nepal. MethodsHospital-based age-matched case-control study was conducted among 50 cases and 150 controls visiting BP Koirala Memorial Cancer Hospital, Bharatpur, Nepal. Semi-structured questionnaire was used to collect information on demographic characters, socio-economic parameters, reproductive history, dietary and personal habits, family history, history of contraception and history of benign breast disease. Height, weight, hip circumference and waist circumference were measured. ResultsMajority of the cases (52%) belonged to the age group of 46-55 years. The significant risk factors were ethnicity of Dalit/Madhesi (AOR 8.222, 95% CI 2.377-28.441, p-value 0.001), parity of 3 to 5 (AOR 5.614, 95% CI 1.140-27.639, p-value 0.03) and previous history of benign breast disease (OR 13.614, 95% CI 3.229-57.391, p-value 0.001). Hysterectomy was found to reduce the risk of breast cancer (OR 0.122, 95% CI 0.017-0.826, p-value 0.03). Knowledge of breast self-examination was significantly higher among cases than controls (AOR 36.29, 95% CI 5.788-227.555, p-value < 0.001). Knowledge of mammography was significantly lower among cases than control (AOR=0.133, 95% CI=0.028-0.647, p-value=0.01). ConclusionThis study showed a number of factors to be associated with the increased risk of breast cancer. It was observed that the mean age at diagnosis is a decade earlier than in Western countries. Genetic component was not significant in context of Nepal. It is hoped that the findings of this study will facilitate further exploration and evidenced-based preventive measures for Nepalese women.

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Determinants of Mother to Child HIV Transmission (HIV MTCT); A Case Control Study in Governmental Health Centers of East Gojjam Zone, Northwest Ethiopia, 2019

10.21203/rs.3.rs-948380/v1 ◽

2021 ◽

Author(s):

Mengistie Kassahun Tariku

Keyword(s):

Logistic Regression ◽

Hiv Transmission ◽

Case Control Study ◽

Case Control ◽

Health Centers ◽

P Value ◽

History Of ◽

Mother To Child ◽

Control Study

Abstract Background: Mother to child human immune virus (HIV) transmission is the passage of HIV from mother to her child during pregnancy, labor, delivery or breast-feeding. The objective of this study was to identify determinants of mother to child HIV transmission in Governmental health centers of East Gojjam Zone, Northwestern Ethiopia, 2019. Methods: A case control study was conducted on 210(42 cases and 168 controls). All cases were included in the study. Controls were selected by simple random sampling. Secondary data were collected from April 1 to 30/2019. Collected data were entered by using epi data version 3.1 and then it was exported to SPSS. The exported data was analyzed and presented by using descriptive summary statistics and tables. After bivariate logistic regression analysis, all variables with p-value 0.25 were entered into multivariable logistic regression and p value < 0.05 considered as significantly associated with the outcome variable.Results: Having history of antenatal care follow up of HIV positive pregnant women [ adjusted odds ratio (AOR)=5.0;95%CI; 2.02-12.16] and initial CD4 count of mothers [AOR=2.7;95%CI;1.35-5.52]. Conclusion: Mother to child HIV transmission was significantly associated with history of ANC follow up of mothers and initial CD4 counts of mothers.

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SERUM PROLACTINE LEVEL IN PATIENTS OF PSORIASIS VULGARIS AND ITS CORRELATION WITH DISEASE SEVERITY: A CASE-CONTROL STUDY

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i6.303 ◽

2019 ◽

Vol 3 (6) ◽

Author(s):

Pawan Kumar Saini ◽

Devendra Yadav ◽

Rozy Badyal ◽

Suresh Jain ◽

Arti Singh ◽

...

Keyword(s):

Disease Severity ◽

Prolactin Level ◽

Case Control Study ◽

Statistical Significance ◽

Case Control ◽

Serum Prolactin ◽

P Value ◽

Serum Prolactin Level ◽

R Value ◽

Control Study

Background: Psoriasis is an autoimmune chronic inflammatory disorder affecting the skin mediated by T-lymphocytes resulting in production of cytokines which cause hyperproliferation of keratinocytes. Several factors and hormones like Prolactin have an action similar to these cytokines in promoting the multiplication of keratinocytes and other cells like lymphocytes and epithelial cells may have a role on the etiopathogenesis of psoriasis. Aim:-The aim of study is to compare the serum Prolactin levels in patients of psoriasis with a control group. Setting and study design: This is a case-control study conducted in the department of Dermatology, Venereology and Leprosy GMC, Kota over a period of 1year from July 2017 to June 2018 Material and method: The study included 100 cases of psoriasis (60 males and 40 females) and 100 controls similar for age and sex. Serum Prolactin levels were measured by ECLIA and results were obtained. Statistical analysis: Mean and standard deviation were calculated for each variable. Statistical significance of the results was analyzed using correlation analysis (Pearson correlation coefficient) and independent samples t-test. Statistical significance was assumed at p value<0.05. Result: Serum Prolactin level was significantly higher in cases of psoriasis compared to controls (p-value <0.001). PASI score and serum Prolactin levels were found to have a positive correlation (r value = 0.337; p-value: 0.001). No significant correlation was found between serum levels of Prolactin and duration of disease r value= -0.034, P value =0.733). Serum Prolactin level was higher in male patients compared to females patients. Conclusion:- High serum Prolactin may be a biological marker of disease severity in psoriasis and may have a role in the pathogenesis of psoriasis. Further studies with large sample size are required to confirm this hypothesis.

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The association between diabetes and thyroid cancer risk: a hospital-based case-control study in China

BMC Endocrine Disorders ◽

10.1186/s12902-021-00684-y ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Meng Wang ◽

Wei-Wei Gong ◽

Feng Lu ◽

Ru-Ying Hu ◽

Qing-Fang He ◽

...

Keyword(s):

Thyroid Cancer ◽

Family History ◽

Case Control Study ◽

Positive Family History ◽

Case Control ◽

Diabetes Duration ◽

Family History Of Diabetes ◽

Thyroid Cancer Risk ◽

History Of ◽

Control Study

Abstract Background Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes duration and the risk of thyroid cancer in Chinese population. Methods A 1:1 matched case-control study was performed between 2015 and 2017 in Zhejiang Province including 2,937 thyroid cancer cases and 2,937 healthy controls. Odds ratios (ORs) with 95 % confidence intervals (CIs) for thyroid cancer were estimated in logistic regression models. Specific effects stratified by age, as well as sex, body mass index (BMI) and family history of diabetes were also examined. Results Overall, neither diabetes (OR = 0.75, 95 % CI: 0.21–2.73) nor diabetes duration (OR = 0.14, 95 % CI: 0.02–1.22 for diabetes duration ≦ 5 years; OR = 2.10, 95 % CI: 0.32–13.94 for diabetes duration > 5 years) was significantly associated with thyroid cancer. In stratified analyses, significant lower risk of thyroid cancer was observed among subjects with diabetes and shorter diabetes duration ( ≦ 5 years), but limited to those who were aged more than 40 years, female, overweight/obese and had positive family history of diabetes. Conclusions Diabetes and shorter diabetes duration were significantly associated with decreased risk of thyroid cancer in individuals characterized by older age, female sex, higher BMI and positive family history of diabetes.

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Association between infection with Campylobacter species, poor oral health and environmental risk factors on esophageal cancer: a hospital-based case–control study in Thailand

European Journal of Medical Research ◽

10.1186/s40001-021-00561-3 ◽

2021 ◽

Vol 26 (1) ◽

Author(s):

Arisara Poosari ◽

Thitima Nutravong ◽

Prakasit Sa-ngiamwibool ◽

Wises Namwat ◽

Supaporn Chatrchaiwiwatana ◽

...

Keyword(s):

Risk Factors ◽

Esophageal Cancer ◽

Oral Hygiene ◽

Case Control Study ◽

Significant Risk ◽

Case Control ◽

Poor Oral Hygiene ◽

History Of ◽

Control Study ◽

History Of Cancer

Abstract Background Previous studies have shown the association between Campylobacter species infection and that environmental factors, poor oral hygiene in particular, are linked to an increased risk of esophageal cancer (EC). However, no study has reported on these factors in Thailand. Thus, this study’s objective was to evaluate the impact of the relationship between Campylobacter infection and environmental factors on EC incidence in the population of Thailand. Methods Data from a case–control study were collected from 105 newly diagnosed EC cases and 105 controls recruited from 2007 to 2017. Infection with Campylobacter spp. was detected in the formalin-fixed paraffin-embedded (FFPE) tissue of EC taken from gastroesophageal biopsy specimens obtained from the participants, and evaluated using TaqMan® real-time PCR. Multivariable logistic regression was performed to calculate the odds ratios (ORs) and perform data analysis. Results Smoking, alcohol use, a family history of cancer, history of gastroesophageal reflux disease, poor oral hygiene and Campylobacter spp. infection were shown to be significant risk factors for EC (p < 0.05). The combination of poor oral hygiene and infection with Campylobacter spp. constituted significant risk for EC (p < 0.001). In addition, the risk of EC in subjects co-infected with C. rectus and C. concisus that practiced poor oral hygiene was even higher and was significant (ORadj = 4.7; 95% CI 2.41–9.98; p = 0.003). Conclusions In Thailand, the major risk factors for EC are smoking status, alcohol drinking, family history of cancer, GERD, poor oral hygiene and Campylobacter spp. infection. This study found Campylobacter spp. prevalence to be associated with EC and appears to be enhanced by poor oral hygiene, suggesting that a combination of poor oral hygiene and Campylobacter species infection may together act as an important etiological risk factor for EC.

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