scholarly journals Birth Month And Prevalence Of Atopic Dermatitis In Children Under 3 Years In Antananarivo, Madagascar

2020 ◽  
Author(s):  
Fandresena Arilala Sendrasoa ◽  
Volatantely Ratovonjanahary ◽  
Mendrika Fifaliana Rakotoarisaona ◽  
Malalaniaina Andrianarison ◽  
Onivola Raharolahy ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
University Hospital ◽  
P Value ◽  
Month Of Birth ◽  
Birth Month ◽  
History Of ◽  
The University ◽  
The Relationship ◽  
Control Study

Abstract BACKGROUND: Several studies have been done to evaluate the relationship between month of birth and atopic diseases but the results are contradictory. So, we aim to evaluate the correlation between the month of birth and the prevalence of AD in Malagasy children less than 3 years.METHODS: A case-control study was conducted based on patients’ data of the department of Dermatology in the University Hospital Joseph Raseta Befelatanana (UH/JRB) Antananarivo. It included 354 children less than 3 years seen in this department between January 2010 and December 2018. For each AD patient, two age and sex-matched controls without a history of AD were selected from the same period.RESULTS: This study included 118 AD cases and 236 non-AD controls. Our case-control study found that there are no statistically significant correlation between birth month and risk of AD in Malagasy children < 3 years. However, the fewest children with AD were born in February (17.86%, OR: 0.40, CI 95%: 0.11-1.14), and the most were born in August (45.16%, OR: 1,73; CI 95%: 0,75-3,88). Asthma, allergic rhinitis and allergic conjunctivitis were significantly correlated with AD in our patients.CONCLUSION: Our case-control study found that there are no statistically significant correlation between birth month and risk of AD in children < 3 years. However, the high frequency of AD in children born in August (dry season) compared to non-AD controls was not negligible (p-value =0,05 and X 2 3,27).

Antioxidant potential of diet: Association between dietary antioxidant index and odds of coronary heart disease: A case-control study

2021 ◽  
pp. 1-13
Author(s):  
Farhad Vahid ◽  
Zahra Nasiri ◽  
Amir Abbasnezhad ◽  
Ezatollah Fazeli Moghadam
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Antioxidant Capacity ◽  
Case Control Study ◽  
Case Control ◽  
P Value ◽  
Dietary Antioxidants ◽  
Dietary Antioxidant ◽  
The Relationship ◽  
Control Study

BACKGROUND: Oxidative stress and chronic inflammation are among the leading causes of coronary heart disease (CHD). Studies investigated the relationship between dietary antioxidants and the risk/odds of CHD, and contradictory results have been reported. Dietary antioxidant index (DAI) is a novel and reliable nutritional tool that examines the diet’s overall antioxidant capacity. Its validity was examined using serum total antioxidant capacity and malondialdehyde. OBJECTIVE: This study aimed to investigate the relationship between DAI score and odds of CHD. METHODS: In this incidence case-control study, 320 individuals with a definitive diagnosis of CHD and 320 participants without CHD or related risk factors attending the same hospitals/polyclinics were selected as the case and control groups. We estimated the DAI by summing up six standardized intakes of major dietary antioxidants, including manganese, vitamin E, A, C, selenium, and zinc. RESULTS: Modeling DAI categorized according to the median (–0.38), in multi-adjusted model showed a significant protective association with the odd of CHD (OR = 0.72; 95%CI:0.51–0.99, p-value = 0.05). Also, modeling DAI as a continuous variable in multi-adjusted models (OR = 0.94;95%CI:0.90–0.95; p-value = 0.01) showed significant results. CONCLUSION: Using the DAI to investigate the relationship between dietary antioxidants and CHD can show more realistic results than a single study of antioxidants.

scholarly journals Frequency of HLA-DRB1 Gene Alleles in Patients With Multiple Sclerosis in a Lithuanian Population

Medicina ◽  
2012 ◽  
Vol 48 (1) ◽  
pp. 2
Author(s):  
Renata Balnytė ◽  
Daiva Rastenytė ◽  
Dalia Mickevičienė ◽  
Antanas Vaitkus ◽  
Erika Skrodenienė ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Case Control ◽  
Chain Reaction ◽  
Female Patients ◽  
History Of ◽  
Male Patients ◽  
Polymerase Chain ◽  
The Relationship ◽  
Control Study

The aim of the present study was to investigate the influence of HLA-DRB1 alleles on the genetic susceptibility to multiple sclerosis in the Lithuanian population. Material and Methods. A total of 120 patients with multiple sclerosis and 120 unrelated healthy controls were enrolled in this case-control study. Allelic frequencies were compared between the groups. HLA-DRB1 alleles were genotyped using the polymerase chain reaction. Results. HLA-DRB1*15 was present in 55.8% of the patients with multiple sclerosis and 10.0% of the controls (OR, 5.58; 95% CI, 3.19–9.77; P<0.0001). The protective alleles that were found to be more prevalent among the controls compared with the patients with multiple sclerosis were HLADRB1* 01 (26.7% vs. 7.5%, P<0.0001), *03 (17.5% vs. 8.3%, P=0.034), and *16 (11.7% vs. 3.3%, P=0.014). HLA-DRB1*15 was more common among the female patients with multiple sclerosis than among the male patients (68.4% vs. 34.1%; OR, 4.18; 95%, CI 1.90–9.22; P=0.001). The heterozygous inheritance of HLA-DRB1*15 allele was more common in the patients with a history of maternal multiple sclerosis than in those with a history of paternal multiple sclerosis (29.4% vs. 9.8%; P=0.045). Conclusions. HLA-DRB1*15 was found to be associated with multiple sclerosis in the Lithuanian population. This allele was more prevalent among the female patients with multiple sclerosis. Maternal multiple sclerosis was more common than paternal multiple sclerosis, but the relationship with HLA-DRB1*15 allele was not established. HLA-DRB1*01, *03, and *16 appeared to be the protective alleles in this series.

scholarly journals Factors Related to Case Of Coronavirus Disease 2019 (Covid-19)

2021 ◽  
Vol 2 (2) ◽  
pp. 57-69
Author(s):  
Neneng Bisyaroh
Keyword(s):  
Quantitative Research ◽  
Case Control Study ◽  
Close Relation ◽  
Case Control ◽  
P Value ◽  
Enabling Factors ◽  
Knowledge And Attitudes ◽  
Reinforcing Factors ◽  
History Of ◽  
Control Study

As of March 24, 2021, in Indonesia there were 1,482,559 confirmed cases. East Java province occupies the third highest cases after DKI Jakarta and West Java Province. Gresik Regency still has many additional confirmed cases. Based on strategic guidelines, prevention efforts are needed, namely the 5M movement, knowledge and attitudes related to prevention efforts that are very important so as not to cause an increase in the number of cases. The purpose of this research was to determine the factors associated with the incidence of Covid-19. This type of research is quantitative research with a case control study design. The results of the study were that 69 respondents (74.2%) had a history of negative status and 24 people (25.8%) had a positive status. Factor related to the history of Covid-19 incidence is enabling factors (affordability of health facilities) with p value = 0.003. Analysis of the close relation between the two variables obtained Odd Ratio = 0.180 (95% CI: 0.060-0.538), and there was no relationship between predisposing factors and reinforcing factors with the incidence of Covid-19 history. ABSTRAK   Terhitung sampai tanggal 24 Maret 2021, di Indonesia tercatat 1,482,559 terkonfirmasi. Provinsi jawa timur menduduki kasus tertinggi ketiga setelah DKI Jakarta dan Provinsi Jawa Barat. Kabupaten Gresik masih banyak penambahan confrim kasus. Berdasarkan panduan strategis diperlukan upaya pencegahan, yaitu gerakan 5M, serta pengetahuan dan sikap terkait upaya pencegahan adalah hal yang sangat penting agar tidak menimbulkan peningkatan jumlah kasus. Tujuan penelitian ini untuk mengetahui faktor–faktor yang berhubungan dengan kejadian riwayat Covid-19. Jenis penelitian ini adalah penelitian kuantitatif dengan desain studi case control. Hasil penelitian adalah responden memiliki riwayat status negatif sebanyak 69 orang (74.2%) dan yang memiliki status positif sebanyak 24 orang (25.8%). Faktor yang berhubungan dengan riwayat kejadian Covid-19 adalah faktor pemungkin (keterjangkauan fasilitas kesehatan) dengan nilai p = 0,003. Analisis keeratan hubungan dua variabel diperoleh Odd Ratio = 0,180 (95% CI : 0,060-0,538), serta tidak ada hubungan antara faktor predisposisi dan faktor penguat dengan kejadian riwayat Covid-19.

scholarly journals Determinants of Severe Acute Malnutrition among Children age 6-59 Months Old in Two Public Hospitals, North West Ethiopia: a Case Control Study

2019 ◽  
Author(s):  
Adonia Damtew Nebro ◽  
Degnet Teferi Asres ◽  
Reddy PCJ Prasad
Keyword(s):  
Exclusive Breastfeeding ◽  
Case Control Study ◽  
Severe Acute Malnutrition ◽  
Case Control ◽  
Hand Washing ◽  
Acute Malnutrition ◽  
P Value ◽  
Monthly Income ◽  
History Of ◽  
Control Study

AbstractIntroductionGlobally sever acute malnutrition affects 16.4 million under five children and more than one quarter of those children live in Africa. In Ethiopia, about 3% of children are severely wasted and continues to be persistent over the past 15 years. To implement an effective intervention, it is essential to identify predictors predispose to it. This study therefore, aimed to identify determinants of severe acute malnutrition among under five children in selected public health facilities, Northwest Ethiopia.MethodsInstitution based; age matched case control study was conducted on 104 cases and 208 controls. Bivariate and multivariate analyses were done using conditional logistic regression to identify predictors. Variables having P-value ≤ 0.2 during binary analysis were entered into multivariate analysis. P value < 0.05 was considered as statistically significant.ResultsChildren from households of large family size(AOR=2.7, 95% CI: 1.06 – 6.9), having monthly income less than 1500 birr (AOR = 5.17, 95% CI: 1.7-15.3), which are food insecure (AOR = 2.9, 95% CI:1.17-7.28)), which didn’t receive any nutrition information (AOR= 3.47,95% CI: 1.14 - 7.10), didn’t practice exclusive breastfeeding (AOR = 2.69, 95% CI: 1.18 - 6.10), and practice infrequent hand washing (AOR= 7.6 95% CI:2.44-23.6) as well as children who had history of diarrhea two weeks prior to the survey (AOR 3.2, 95%CI:1.4-7.2) were more likely to suffer from severe acute malnutrition.ConclusionFamily size, monthly income, food security status, exclusive breastfeeding practice, access to information on child feeding, hand washing practice and history of diarrhea were identified to be predictors of severe acute malnutrition. Due emphasis should be given to promoting family planning, improve household livelihoods and food security, strength awareness creation on exclusive breastfeeding and frequent hand washing practices as well as prevention of diarrhea.

scholarly journals Correlation between Incidence of Diarrhea in Toddlers and Housewife’s Clean and Healthy Lifestyle

2020 ◽  
Vol 7 (1) ◽  
pp. 57
Author(s):  
Teuku Alamsyah ◽  
Dewi Marianthi
Keyword(s):  
Case Control Study ◽  
Healthy Lifestyle ◽  
Case Control ◽  
Hand Washing ◽  
P Value ◽  
The Public ◽  
One Year ◽  
The One ◽  
The Relationship ◽  
Control Study

Diarrhea is one of the public health problems, particularly in infants. Based on the outcomes of the Aceh Besar fitness service survey, Baitussalam sub-district is one of the districts with a excessive wide variety of diarrhea cases, with a total of 520 instances in the one year. This is due to the lack of exact hygiene conduct related to hand washing cleaning soap in the prevention of diarrhea in toddlers. This research ambitions to find out the relationship between the clean and healthy lifestyle housewives on behavior of smooth water use and waste management with diarrhea in children of Baitussalam Subdistrict in Aceh Besar District, Indonesia. This is a descriptive analytic study using a case control study, consist of 28 moms who have children who suffer from diarrhea, and 28 moms who have youngsters do not go through from diarrhea. This lookup resulted in three findings namely there is a relationship between handwashing with cleaning soap with the incidence of diarrhea in infants (p-value 0.003 < α = OR 3.50), there is no relationship between the use of smooth water with the incidence of diarrhea in babies (p-value 1.00 > α = 0.05, OR 1.22) and there is a management relationship with the incidence of diarrhea in teens under five (p-value 0.01 < α = 0.05, OR 4.50).

scholarly journals Determinants of neonatal near misses among neonates admitted to Guji and Borena zones selected public hospitals, Southern Ethiopia, 2021: A facility based unmatched case control study design

2022 ◽  
Vol 2 (1) ◽  
pp. e0000168
Author(s):  
Anteneh Fikrie ◽  
Elias Amaje ◽  
Amana Jilo Bonkiye ◽  
Wako Golicha Wako ◽  
Alqeer Aliyo ◽  
...  
Keyword(s):  
Birth Interval ◽  
Neonatal Death ◽  
Case Control Study ◽  
Case Control ◽  
Public Hospitals ◽  
Southern Ethiopia ◽  
P Value ◽  
Near Misses ◽  
History Of ◽  
Control Study

There is little available evidence that quantifies the determinats of NNM in Ethiopia despite an increasing magnitude of neonatal mortality. Therefore, this study was designed to provide concrte evidence about the determinats of NNMS among neonates admitted to Guji and Borena Zones Public Hospitals, Southern Ethiopia, 2021. A facility based unmatched case control study design was conducted on 402 (134 cases and 268 controls) selected neonates admitted to Bule Hora, Adola and Yabelo General Hospitals from February 1-March 31, 2021. Cases were consecutively selected. Whereas for each case, two controls were selected by systematic random sampling technique. The data collection included a pretested and structured face-to-face interviewer administered questionnaire with a supplementation of maternal and neonatal medical records with checklists. Then the data were coded and entered in to Epi data version 3.1 and then exported to the Statistical Package for Social Science IBM version 25 for analysis. The descriptive statistics run and the results of the data were presented using frequencies, and tables. Bivariable and multi variable logistic regression was used for the analsysis of the data. Finally, Adjusted Odds Ratio together with 95% Confidence Intervals and p value <0.05 was used to declare the significance of all statistic. A total of 134 cases (neonatal near misses) and 268 controls (normal neonate) were participated in this study to make a response rate of 100% for both cases, and controls. In this study rural residence (AOR = 0.51, 95% CI: 0.27, 0.96), previous history of neonatal death (AOR = 4.85, 95%CI: 2.24,10.49), birth interval ≤ 2 years (AOR = 1.83, 95% CI: 1.04, 3.11) and history of abortion (both induced and miscarriage) (AOR = 1.97, 95%CI: 1.17, 3.31) were found to be statistically significant at a p-value of <0.05. History of prior abortion history of prior neonatal death and short birth interval (≤ 2 years) were identified to be the determinats of NNMs. High quality antenatal and intrapartum continuum of care should be provided for women and neonates. Additionally, contraceptive utilization should be encouraged for a women to space the births of their children.

scholarly journals COBALAMIN DEFICIENCY

2016 ◽  
Vol 23 (02) ◽  
pp. 176-181
Author(s):  
Shumaila Shaikh ◽  
Azhar Memon ◽  
Muhammad Atif Ata ◽  
Haji Khan Khoharo
Keyword(s):  
Helicobacter Pylori ◽  
Case Control Study ◽  
Case Control ◽  
University Hospital ◽  
Cobalamin Deficiency ◽  
P Value ◽  
Significant Difference ◽  
Design Case ◽  
H Pylori ◽  
Control Study

Objectives: The present study aims to evaluate the serum cobalamin inHelicobacter pylori (H. pylori) infected patients. Study Design: Case control study. Place andDuration: Department of Medicine, Isra University Hospital Hyderabad from March 2013- April2014. Methodology: A sample of 109 subjects including Helicobacter pylori positive subjectsand controls were selected according to study criteria. Centrifugation of blood was performedat 4000 rpm for 10 minutes and sera were stored at -20oC. Blood sera were used for H. pyloriserological testing. Blood counting was performed on hematoanalyzer. Cobas e411 analyzerwas used for detection of cobalamin. 64 kD H. pylori antigens was detected by ELISA. Thedata was entered into SPSS version 21.0. (IBM, Incorporation, USA) A 2-tailed p-value of ≤0.05was considered significant for statistical analysis. Results: Of total 109, 54.1% (n=59) wereH. pylori seropositive cases and others were controls i.e. 45.9% (n=50). Cases and controlsshowed cobalamin levels of 290±49.3 vs. 351±32.9 pg/ml respectively (p=0.0001). Red bloodcell indices were found to show statistically significant difference between cases and controls(p=0.001). Conclusion: Serum cobalamin deficiency was noted in both Helicobacter pyloripositive and controls, however deficiency was more pronounced in Helicobacter pylori positivesubjects.

Analisis Faktor Ibu yang Pernah Bersalin Nomal Mengalami Risiko Bedah CCaesarea

2019 ◽  
Vol 4 (2) ◽  
pp. 1
Author(s):  
Siti maisyaroh Fitri Siregar
Keyword(s):  
Case Control Study ◽  
Sampling Technique ◽  
Case Control ◽  
Bivariate Analysis ◽  
P Value ◽  
Chi Square ◽  
Chi Square Test ◽  
History Of ◽  
Dominant Influence ◽  
Control Study

ABSTRACT               The objective of the research was to analyze the risk factors of  women with the history of normal childbirth had delivery by section caesarea.             The research used observational analytic method with case-control study design. The samples consisted of 42 cases and 42 controls, taken by using consecutive sampling technique. Dependent variable was childbirth with CS and independent variables were parity, accompanied illness, and reference. The gathered data were analyzed by using univatriate analysis, bivariate analysis with chi square test, and multivatriate analysis at α = 0.05.             The result of the research from multivariate analysis showed that the variables which had significant influence on childbirth with SC were parity (p = 0.006; OR = 5.801 95% CI = 1.642-19.110),accompanied illness (p = 0.03; OR = 6.382 95% CI = 1.198-33.992), and reference (p = 0.003; OR = 6.350 95% CI = 1.874-21.522). The variable which had the most dominant influence childbirth with CS was accompanied illness. p-value = 97% which indicated that childbirth women with the parity > 2 had accompanied illness and the reference to the hospital had the possibility to give birth with CS of 97%.             It is recommended to do family planning programme, and prevent the illness during pregnant, apply ANC according to the standard, and make sure that the childbirth is safe from Period I to Period III.   Keywords: Risk Factor, Caesarea, Case-Control

scholarly journals The seasonality, steroid use, and lower ratio of neutrophil to lymphocyte associated with bacteremia of Listeria monocytogenes in Japan from 2010 to 2019: a case–control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yusuke Watanabe ◽  
Itaru Nakamura ◽  
Yuri Miura ◽  
Hidehiro Watanabe
Keyword(s):  
Mortality Rate ◽  
Case Control Study ◽  
Warm Season ◽  
Case Control ◽  
University Hospital ◽  
Control Group ◽  
P Value ◽  
Steroid Use ◽  
Lower Ratio ◽  
Control Study

Abstract Background Despite having a high mortality rate, Asian studies about the characteristics of adult listeriosis are limited. We investigated the incidence of listeriosis per admissions, associated factors, and rate of mortality in listeriosis, compared with non-listeriosis. Methods We recorded the incidence of listeriosis per 10,000 admissions and conducted a case–control study from January 1, 2010, to December 31, 2019, at Tokyo Medical University Hospital (TMUH) in Japan. Cases were defined as adult with listeriosis that was bacteremia due to L. monocytogenes. Controls, defined as adult with non-listeriosis bacteremia due to other pathogens, were matched by age and clinical department to cases. We analyzed differences in seasonality, including warm season (defined as the period from May to October), medication including steroids, laboratory findings, and mortality. The odds ratio and p value between the cases group and control group were calculated using a chi-square test and Fisher’s exact test. Results The incidence of listeriosis per 10,000 admissions to TMUH was 0.51. Eleven patients, excluding one neonate, were included in the case group. Twenty-six patients, excluding one patient because of contamination and one patient because of insufficient medical record, were included in the control group. Listeriosis onset was associated with the warm season (90.9% vs. 53.8%; p = 0.033), steroid use (54.5% vs. 19.2%; p = 0.042), and a lower ratio of neutrophils to lymphocytes (9.46 vs. 18.44; p = 0.015). The 30-day mortality rate of listeriosis was similar to non-listeriosis (18.3% vs. 19.2%; p = 0.619). Conclusion The incidence of listeriosis per admissions in this study was similar to that in other Asian countries. Factors associated with listeriosis were the warm season, steroid use, and a lower ratio of neutrophils to lymphocytes. Additionally, the 30-day mortality rate was similarly high in both the listeriosis and non-listeriosis groups.

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