scholarly journals Gambaran kadar asam urat darah pada pekerja kantor

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Pibi S. Darmawan ◽  
Stefana H.M. Kaligis ◽  
Youla A. Assa
Keyword(s):  
Physical Activity ◽  
Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Sampling Method ◽  
Office Workers ◽  
Normal Blood ◽  
Cross Sectional ◽  
Blood Uric Acid ◽  
Cross Sectional Design

Abstract: Prolonged hyperuricemia is the cause of gout arthritis, which has become one of burden diseases in the wide society. Several conditions can increase hyperuricemia and one of that conditions is insulin resistance associated with decreased physical activity. People with low physical activity like office workers have a higher risk of hyperuricemia. This study was aimed to describe the level of blood uric acid among office workers. This was a descriptive study with a cross-sectional design using total sampling method to obtain respondents. The results showed that there were 52 respondents in this study. Thirty eight respondents (79,1%) had normal blood uric acid level and 14 respondents (26,9%) had high blood uric acid level. The average of blood uric acid level was 6,09 mg/dL,the median was 6.15 mg/dL, the minimum and maximum values were 3 mg/dL and 9,36 mg/dL respectively, and the standard of deviation was 1,615 mg/dL. Of 14 respondents with high blood uric acid level, one was female (7.1%) and the rest were males (92.9%). Conclusion: The majority of office workers had normal blood uric acid.Keywords: blood uric acid, office workers. Abstrak: Hiperurisemia yang berkepanjangan merupakan penyebab terjadinya penyakit gout arthritis, yang telah menjadi salah satu beban penyakit dimasyarakat. Beberapa keadaan dapat meningkatkan kejadian hiperurisemia, salah satunya ialah resistensi insulin yang terkait dengan penurunan aktivitas fisik. Orang dengan aktivitas fisik yang rendah seperti pekerja kantor berisiko tinggi terhadap terjadinya hiperurisemia. Penelitian ini bertujuan untuk mengetahui gambaran kadar asam urat pada pekerja kantor. Jenis penelitian ialah deskriptif dengan metode total sampling. Hasil penelitian mendapatkan 52 pekerja kantor sebagai responden. Terdapat 38 orang (79,1%) memiliki kadar asam urat dalam batas normal dan 14 orang (26,9%) memiliki kadar asam urat tinggi. Nilai rerata kadar asam urat darah 6,09 mg/dL, nilai median 6,15 mg/Dl, nilai minimum dan maksimum pada 3 mg/dL dan 9mg/dL serta standar deviasi 1,615 mg/dL. Dari 14 responden tersebut terdapat satu orang perempuan (7,1%) sedangkan sisanya ialah laki-laki (92,9%) . Simpulan: Sebagian besar pekerja kantor memiliki kadar asam urat darah normal. Kata kunci: asam urat darah, pekerja kantor.

scholarly journals POLA KONSUMSI SUMBER PURIN, AKTIVITAS FISIK DAN STATUS GIZI DENGAN KADAR ASAM URAT PADA LANSIA DI PUSKESMAS KECAMATAN MAKASAR JAKARTA

2020 ◽  
Vol 4 (1) ◽  
pp. 84
Author(s):  
Gina Ganda Fitriana ◽  
Adhila Fayasari
Keyword(s):  
Physical Activity ◽  
Uric Acid ◽  
Nutritional Status ◽  
Uric Acid Level ◽  
Acid Level ◽  
Consumption Pattern ◽  
Chi Square ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Significant Difference

Degenerative processes can decrease the endurance in elderly that leads to health problem such as gout. Gout is a metabolic disorder, which is indicated by an increase uric acid in bloodstream (hyperuricemia). Factors affecting high level of uric acid are purine intake, physical activity and nutritional status. The aim of this study was to analyze the relationship between consumption pattern of purine source food, nutritional status and physical activity with uric acid level in elderly. The study design was cross sectional. The sample consisted of 100 subyekts at Puskesmas Kecamatan Makasar. The analytical used chi square. Patterns of food consumption of purine sources were measured using FFQ questionnaires which was then cut off into into 2 categories: low-moderate purine category with score <55 and high purine category with a score of ≥55 physical activity and nutritional status were measured using questionnaires, uric acid levels was obtained by looking at laboratory results or from patients' medical records. There was 10% of subyekts withlo- moderate uric acid levels and 90% of subyekts with high purine consumption pattern. Based on the results of chi square test there was a significant difference (p <0.05) between the consumption pattern of purine source food with normal uric acid and high uric acid. There was a relationship between consumption pattern of purine food source with uric acid level in elderly.

scholarly journals Gambaran Kadar Asam Urat Serum pada Remaja dengan Overweight dan Obesitas

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Inggrianno G.V Matialu ◽  
Murniati Tiho ◽  
Youla A. Assa
Keyword(s):  
Uric Acid ◽  
High School Students ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Overweight And Obesity ◽  
School Students ◽  
Cross Sectional ◽  
Cross Sectional Design ◽  
Level Profile

Abstract: Nowadays, obesity has become a serious problem world-wide. Obesity can cause the emergence of various kinds of diseases; one of them is hyperuricemia. This condition could found in obese adult as well as in obese adolescence. This study was aimed to obtain the serum uric acid level profile among high school students with overweight and obesity. This was a descriptive study with a cross sectional design. Subjects were grade X-XI students of SMA Negeri 2 Bitung with body mass index (BMI) >85. There were 23 students involved in this study. The results showed that 60.87% subjects had hyperuricemia. Conclusion: Most adolescence with obesity tend to have uric acid level above normal value.Keywords: adolescence, obesity, hyperuricemia, serum uric acidAbstrak: Obesitas saat ini sudah menjadi sebuah permasalahan serius bagi dunia. Obesitas dapat menyebabkan timbulnya berbagai penyakit seperti hiperurisemia. Masalah hiperurisemia tidak hanya terjadi pada orang dewasa yang obes tetapi juga dapat menyerang remaja yang obes. Penelitian ini bertujuan mengetahui gambaran kadar asam urat serum pada siswa yang mengalami overweight maupun obesitas. Jenis penelitian ini ialah deskriptif dengan desain potong lintang. Subjek penelitian ialah siswa kelas X-XI SMA Negeri 2 Bitung yang memiliki IMT diatas persentil 85 sebanyak 23 siswa. Hasil penelitian menunjukkan bahwa sebanyak 60,87% siswa mengalami hiperurisemia. Simpulan: Remaja dengan obesitas cenderung memiliki kadar asam urat di atas normal.Kata kunci: remaja, obesitas, hiperurisemia, asam urat serum

scholarly journals Increased Uric Acid and Life Style Factors Associated with Metabolic Syndrome in Thais

2020 ◽  
Vol 30 (2) ◽  
Author(s):  
Suwit Klongthalay ◽  
Kanjana Suriyaprom
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Significant Risk ◽  
Cross Sectional

BACKGROUND: The prevalence of metabolic syndrome (MS) has been continually increasing in developing countries especially in Thailand. Although insulin resistance and central obesity are initially considered as significant risk factors, the other causal factors leading to the development of MS continue to challenge the investigators. The aims of this study were to evaluate the prevalence of MS in Pathum Thani province, Thailand and to investigate the relationship between MS and risk factors.METHODS: This cross-sectional study was performed with 202 Thai volunteers. Anthropometric-biochemical variables and blood pressures in each subject were measured.RESULTS: Almost one-third (32.7%) of the participants were diagnosed with MS based on the harmonized criteria, and one of the most significant risk factors is the elevated blood pressure. Weight, BMI, waist and hip circumferences, waist-hip ratio, blood pressure, glucose, triglycerides and uric acid were significantly higher in subjects with MS subjects. However, HDL-C levels were significantly lower in subjects with MS, compared to subjects without MS (p<0.001). The results of regression model after adjustment for age and gender showed that the increased serum uric acid level (OR=1.31, 95%CI: =1.04-1.66), cigarette smoking (OR=3.72, 95%CI: =1.51-9.15) and physical activity (OR=0.36, 95%CI: =0.19-0.67) were significantly related to MS.CONCLUSIONS: These findings suggest that the decrease of uric acid level, the promotion of physical activity and smoking cessation may decrease the risk of developing MS among Thais.

scholarly journals AB0932 FACTORS IN ACHIEVING TARGET SERUM URIC ACID LEVELS IN OUTPATIENT GOUT MANAGEMENT IN A MALAYSIAN TERTIARY RHEUMATOLOGY CENTRE

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1766.2-1766
Author(s):  
M. H. Mustapha ◽  
H. Baharuddin ◽  
N. Zainudin ◽  
S. S. Ch’ng ◽  
H. Mohd Yusoof ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Cross Sectional Study ◽  
British Society ◽  
Treat To Target ◽  
Tophaceous Gout ◽  
Cross Sectional ◽  
The Mean

Background:Gout is one of the most common inflammatory arthropathies. A target serum uric acid of less than 300µmol/l is recommended when tophi are present, and less than 360µmol/l for non-tophaceous gout. Urate-lowering therapy (ULT) should be titrated until the target is achieved and long-term maintenance of the target concentration is recommended. Although ULT has been proven to reduce the uric acid level, less than half of treated patients achieved the target serum uric acid (sUA) in real-world clinical practice.Objectives:To assess the mean treat-to-target achievement in outpatient management of gout by the tertiary rheumatology centre and to identify factors influencing the success rate.Methods:Retrospective cross-sectional study of all patients with gout attending out-patient clinics in a rheumatology referral centre from 1stJanuary 2018 until 31stDecember 2018. Electronic medical records were reviewed. The successful target achievement is defined as mean of all available sUA in 2018 which is ≤360 and ≤300µmol/l for non-tophaceous and tophaceous gout respectively. Chronic kidney disease (CKD) is defined as glomerular filtration rate of less than 60ml/min.Results:There were 251 patients analysed with mean age of 56.3±13.8 years and disease duration of 10.5±9.2 years. Majority were males (215, 85.7%) and 133 (53%) patients had tophaceous gout. The rate of success achieving the target SUA level of ≤360 and ≤300µmol/l were 33.9% (40) and 15.8% (21) in non-tophaceous and tophaceous gout respectively. However, in patients who are compliant, the target sUA achieved is 52.4% (33) and 31.7% (19) in non-tophaceous and tophaceous gout respectively. Characteristics of patients who achieved the targeted sUA were patients of more than 50 years old (48, 78.7%), without family history of gout (29, 65.9%), were prescribed colchicine prophylaxis upon initiating ULT (46, 76.7%), with absence of joint erosions (34, 73.9%) and those with normal creatinine clearance (40, 65.5%). There were 120 (48.4%) patients who were compliant to ULT. In 42 compliant patients who achieved target sUA, the mean allopurinol dose is 289.66mg±101.2 and 369.23mg±175 in non-tophaceous and tophaceous gout respectively. Sub-analysis in 31 compliant CKD patients, revealed no difference in allopurinol dose between those who achieved versus non-achieved target sUA (mean 243mg versus 263mg respectively). However, we noted that 11 (61%) CKD patients with tophi did not achieved target sUA at dose less than 300mg allopurinol. Lower achievement of target sUA was significantly associated with presence of tophi (p=0.001), poor compliance (p= 0.000) and presence of more than one comorbidity (p=0.041).Conclusion:There are several challenges in achieving target uric acid level contributed by both patient and clinician factors such as compliance, presence of comorbidity and ULT dose. Our study suggests that higher dosage of allopurinol is required in patients with tophaceous gout, with or without renal impairment. However, the limitation of this study is, the small number of subjects which therefore needsfurtherinvestigation.References:[1]Roddy, E., Packham, J., Obrenovic, K., Rivett, A., & Ledingham, J. M. (2018). Management of gout by UK rheumatologists: a British Society for Rheumatology national audit. Rheumatology, 57(5), 826–830.[2]Katayama A, Yokokawa H, Fukuda H, et al. Achievement of Target Serum Uric Acid Levels and Factors Associated with Therapeutic Failure among Japanese Men Treated for Hyperuricemia/Gout. Intern Med. 2019;58(9):1225–1231.Disclosure of Interests:Mariam Hamid Mustapha: None declared, Hazlyna Baharuddin Speakers bureau: Sanofi, J&J, Norliza Zainudin: None declared, Shereen Suyin Ch’ng Speakers bureau: Novartis, Pfizer, GSK, Habibah Mohd Yusoof: None declared, Ing Soo Lau: None declared, Mollyza Mohd Zain: None declared, Azmillah Rosman: None declared

Blood Uric Acid Level and IQ: A Study in Twin Families

1984 ◽  
Vol 33 (2) ◽  
pp. 237-242 ◽  
Author(s):  
E. Inouye ◽  
K.S. Park ◽  
A. Asaka
Keyword(s):  
Uric Acid ◽  
Uric Acid Level ◽  
Quantitative Traits ◽  
Acid Level ◽  
Genetic Basis ◽  
Plasma Uric Acid ◽  
Blood Uric Acid ◽  
Twin Children ◽  
Twin Families ◽  
Familial Environment

AbstractApplying newly devised model, heritability (VA/VP) of plasma uric acid level, corrected for age and sex and standardized, was estimated at 0.8 in families consisting of twin parents, spouses and children. Correlation between spouses due to common genotype (ρ) was approximately 0.1, and variance due to common familial environment (VEC/Vp) was -0.3. Analysis of families of selected twin children and their parents resulted in two estimates of heritability: approximately 0.7 and 0.3, ρ being 0.34 and 0.04, and VEC/Vp being 0.04 and 0.34, respectively. Regression of IQ (y) on corrected and standardized plasma uric acid level (x) in the twin children was y = 5.56x + 123, correlation being 0.334 (p < 0.025). The result indicates a genetic basis of blood uric acid level, which may have resulted from polymorphisms in purine metabolism pathway, end product of which is uric acid in man. The significant correlation between plasma uric acid level and IQ suggests a contribution of partly common gene loci to the two quantitative traits.

GW24-e1836 Correlation between blood uric acid level and severity of coronary lesions

Heart ◽  
2013 ◽  
Vol 99 (Suppl 3) ◽  
pp. A177.1-A177
Author(s):  
Zhang Quan-Yu ◽  
Han yaling
Keyword(s):  
Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Blood Uric Acid ◽  
Coronary Lesions

scholarly journals Prevalence of asymptomatic hyperuricemia and its association with prediabetes, dyslipidemia and subclinical inflammation markers among young healthy adults in Qatar

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Yasemin Al Shanableh ◽  
Yehia Y. Hussein ◽  
Abdul Haseeb Saidwali ◽  
Maryam Al-Mohannadi ◽  
Budoor Aljalham ◽  
...  
Keyword(s):  
Young Adults ◽  
Uric Acid ◽  
Linear Regression ◽  
Multiple Linear Regression ◽  
Correlation Coefficient ◽  
Uric Acid Level ◽  
Acid Level ◽  
Linear Regression Analysis ◽  
Subclinical Inflammation ◽  
Cross Sectional

Abstract Aim The aim of this study is to investigate the prevalence of asymptomatic hyperuricemia in Qatar and to examine its association with changes in markers of dyslipidemia, prediabetes and subclinical inflammation. Methods A cross-sectional study of young adult participants aged 18 - 40 years old devoid of comorbidities collected between 2012 and 2017. Exposure was defined as uric acid level, and outcomes were defined as levels of different blood markers. De-identified data were collected from Qatar Biobank. T-tests, correlation tests and multiple linear regression were all used to investigate the effects of hyperuricemia on blood markers. Statistical analyses were conducted using STATA 16. Results The prevalence of asymptomatic hyperuricemia is 21.2% among young adults in Qatar. Differences between hyperuricemic and normouricemic groups were observed using multiple linear regression analysis and found to be statistically and clinically significant after adjusting for age, gender, BMI, smoking and exercise. Significant associations were found between uric acid level and HDL-c p = 0.019 (correlation coefficient -0.07 (95% CI [-0.14, -0.01]); c-peptide p = 0.018 (correlation coefficient 0.38 (95% CI [0.06, 0.69]) and monocyte to HDL ratio (MHR) p = 0.026 (correlation coefficient 0.47 (95% CI [0.06, 0.89]). Conclusions Asymptomatic hyperuricemia is prevalent among young adults and associated with markers of prediabetes, dyslipidemia, and subclinical inflammation.

scholarly journals Hubungan jenis kelamin, status gizi, konsumsi susu dan olahannya dengan kadar asam urat pada lansia

2019 ◽  
Vol 7 (2) ◽  
pp. 133-137
Author(s):  
Anugrah Novianti ◽  
Eriliyabuduni Ulfi ◽  
Lilik Sri Hartati
Keyword(s):  
Uric Acid ◽  
Risk Factor ◽  
Uric Acid Level ◽  
Dairy Products ◽  
Acid Level ◽  
Health Workers ◽  
The Elderly ◽  
Overweight And Obesity ◽  
Primary Data ◽  
Cross Sectional

Background: The prevalence of gout increased based on age, highest at age 70-79 years 9.3%, age 60-69 years 8%, age 50-59 years 3.7%, and age 40-49 years 3.3%. Meanwhile, based on gender, the prevalence of gout diagnosed with health workers was higher in women at 13.4% compared to men 10.3%. Overweight and obesity can trigger an increase in uric acid levels, so it is one of a risk factor for hyperuricemia. Various high protein and purine foods have long been considered a risk factor for gout. Similarly, the possibility that consumption of dairy products especially cow's milk has a role in protecting the risk of gout based on the results of metabolic studies.Objective: To determined the relationship of sex, body mass index (BMI), dairy products consumption and uric acid levels of the elderly in Cipondoh Sub-District Tangerang.Methods: This study used a cross-sectional design. Research participants were collected by using purposive sampling. Primary data consisted of respondent characteristics, dairy products consumption, BMI, and uric acid levels.Results: The results of this research have shown there was a correlation between BMI and uric acid level p = 0.007, dairy products consumption and uric acid level p = 0.0001, but there was no correlation between sex and uric acid level p = 0.204 in the elderly at Cipondoh Sub-District Tangerang.Conclusion: There was a correlation between BMI, dairy products consumption with uric acid levels of the elderly in Cipondoh Sub-District Tangerang.

Is lower uric acid level better? A combined cross-sectional and longitudinal study in the elderly

Endocrine ◽  
2014 ◽  
Vol 47 (3) ◽  
pp. 806-815 ◽  
Author(s):  
Chang-Hsun Hsieh ◽  
Jiunn-Diann Lin ◽  
Chung-Ze Wu ◽  
Chun-Hsien Hsu ◽  
Dee Pei ◽  
...  
Keyword(s):  
Uric Acid ◽  
Longitudinal Study ◽  
Uric Acid Level ◽  
Acid Level ◽  
The Elderly ◽  
Cross Sectional

scholarly journals Serum uric acid level in Bangladeshi adults with essential hypertension

2020 ◽  
Vol 7 (7) ◽  
pp. 1136
Author(s):  
SK. Kabir Ahammed ◽  
A. B. M. Kamrul Hasan ◽  
Mohammed Ruhul Kabir ◽  
Gunosindhu Paul ◽  
Shishir Kumar Basak ◽  
...  
Keyword(s):  
Uric Acid ◽  
Essential Hypertension ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Control Group ◽  
Cross Sectional ◽  
Hypertensive Group ◽  
Positive Correlations

Background: The association of hyperuricemia with various cardiovascular risk factors has often led to the debate of whether hyperuricemia is an independent risk factor for essential hypertension (HTN).  The current study was conducted to see the relationship between serum uric acid and essential HTN in Bangladeshi adults.Methods: In this cross-sectional study, conducted in a tertiary hospital of Bangladesh, 155 patients with essential hypertension (newly detected or on treatment) aged ≥18 years and 100 age-sex matched normotensive subjects were investigated. Serum uric acid, plasma glucose, serum creatinine, and lipid profile were measured in all in fasting samples.Results: The frequency of hyperuricemia was higher in the hypertensive group in comparison to the normotensive control group (29.7% vs. 6.0%, p<0.001). Serum uric acid level was higher in the hypertensive subjects than the controls (6.10±0.88 vs. 5.38±0.54 mg/dL, mean±SD, p<0.001). In the hypertensive group, subjects with stage II HTN had higher serum uric acid than those with stage I HTN (6.46±0.83 vs. 5.72±0.78 mg/dL, mean±SD, p<0.001). In the hypertensive group, uric acid level showed significant positive correlations with both systolic and diastolic blood pressure though in the control group uric acid showed such correlation with systolic BP only.Conclusion: Patients with essential hypertension had higher serum uric acid compared to normotensive controls; uric acid level showed positive correlations with systolic and diastolic BP in the hypertensive subjects.

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