scholarly journals HUBUNGAN BEBERAPA FAKTOR RISIKO PENYAKIT JANTUNG KORONER DENGAN LAJU FILTRASI GLOMERULUS PADA PASIEN INFARK MIOKARD LAMA

e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Yanti Manoy
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Glomerular Filtration Rate ◽  
Significant Relationship ◽  
Filtration Rate ◽  
Cross Sectional ◽  
Old Myocardial Infarction ◽  
History Of

Abstract: Old myocardial infarction (OMI) is a major disease of pre hospitalization. The patients who suffer OMI disease have a pain and mortality rate higher than those who do not. This is due to have as many OMI disease risk factors for coronary heart disease (CHD) is owned and usually decrease the glomerular filtration rate (GFR). Methods: This is a descriptive study with cross sectional analytic use the data of medical records at the heart of poly Hospital prof. Dr. R. D. Kandou Manado. Results: There were 205 patients from a total of 330 patients OMI period January 2013 - December 2013 is included as a sample in this study. The results showed that patients aged 60-69 OMI most with 77 people (38 %) with decreased GFR (p=0.000). Patients with a history of hypertension, there are 148 people (72 %) with decreased GFR (p=0,048). Patients with increased LDL there are 166 people (80.9 %) with decreased GFR (p=0.088). Patients who have a history of diabetes, there are 50 men (24.4 %) with decreased GFR (p=0.333). Patients with a history of smoking are 41 people (20 %) with decreased GFR (p=0.103). Conclusion: There is a significant relationship between age and history of hypertension in patients OMI with GFR. There was no significant relationship between hyperlipidemia, diabetes mellitus and a history of smoking history in patients OMI with  GFR.Keywords: Risk factors of Coronary Heart Disease, Glomerular Filtration Rate, Old Myocardial Infarction. Abstrak: Infark miokard lama/Old myocardial infarction (OMI) merupakan penyakit utama prehospitalisasi. Pasien yang mempunyai penyakit OMI memiliki angka kesakitan dan kematian lebih tinggi dibanding yang tidak karena banyaknya faktor risiko penyakit jantung koroner (PJK) yang dimiliki dan biasanya menurunkan laju filtrasi glomerulus (LFG). Metode: Ini adalah penelitian yang bersifat deskriptif analitik cross sectional dengan menggunakan data rekam medik di poli jantung RSUP Prof. Dr. R. D. Kandou Manado. Hasil: Terdapat 205 pasien dari total 330 pasien OMI periode Januari 2013 – Desember 2013 yang dimasukan sebagai sampel dalam penelitian ini. Hasil penelitian menunjukan bahwa pasien OMI paling banyak  berusia 60-69 dengan 77 orang (38%) memiliki LFG menurun (p=0,000). Pasien dengan riwayat hipertensi terdapat 148 orang (72%) dengan LFG menurun (p=0,048). Pasien dengan LDL meningkat terdapat 166 orang (80,9%) dengan LFG menurun (p=0,088). Pasien yang mempunyai riwayat DM terdapat 50 orang (24,4%) dengan LFG menurun (p=0,333). Pasien dengan riwayat merokok terdapat 41 orang (20%) dengan LFG menurun (p=0,103). Kesimpulan: Terdapat hubungan yang signifikan antara usia dan riwayat hipertensi  dengan LFG pada pasien OMI. Tidak terdapat hubungan yang signifikan antara hiperlipidemia, riwayat DM dan riwayat merokok dengan LFG pada pasien OMI.Kata Kunci: Faktor Risiko Penyakit Jantung Koroner, Laju Filtrasi Glomerulus, Infark Miokard Lama.

scholarly journals Is e-cigarette use associated with coronary heart disease and myocardial infarction? Insights from the 2016 and 2017 National Health Interview Surveys

2019 ◽  
Vol 10 ◽  
pp. 204062231987774 ◽  
Author(s):  
Konstantinos E Farsalinos ◽  
Riccardo Polosa ◽  
Fabio Cibella ◽  
Raymond Niaura
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
National Health ◽  
Pooled Analysis ◽  
Cigarette Use ◽  
Cross Sectional ◽  
Health Interview ◽  
Cross Sectional Design

Background: This study analyzed the National Health Interview Surveys (NHIS) of 2016 ( n = 33,028) and 2017 ( n = 26,742) to examine whether e-cigarette use is consistently associated with myocardial infarction (MI) and coronary heart disease (CHD). Methods: Surveys were examined separately and pooled. Logistic regression analysis was used, with demographics, e-cigarette use, smoking and risk factors for CHD (hypertension, hypercholesterolemia, and diabetes) being independent variables. Former smokers were subclassified according to quit duration (⩽ 6 and > 6 years). Results: For MI, an association was observed with some days e-cigarette (but not daily) use in the 2017 survey (OR: 2.11, 95% CI: 1.14–3.88, p = 0.017). No statistically significant association was observed in the pooled analysis (daily e-cigarette use: OR: 1.35, 95% CI: 0.80–2.27, p = 0.267). For CHD, an association was observed with daily e-cigarette use in the 2016 survey (OR: 1.89, 95% CI: 1.01–3.53, p = 0.047). From the pooled analysis, no association was found between any pattern of e-cigarette use and CHD. In single-year and pooled analysis, both MI and CHD were strongly associated with all patterns of smoking, hypertension, hypercholesterolemia, diabetes, and age. Conclusions: The pooled analysis of the 2016 and 2017 NHIS showed no association between e-cigarette use and MI or CHD. The associations between established risk factors, including smoking, and both conditions were remarkably consistent. The inconsistent associations observed in single-year surveys and the cross-sectional design of the NHIS cannot substantiate any link between e-cigarette use and an elevated risk for MI or CHD. Longitudinal studies are needed to explore the effects of e-cigarette use on cardiovascular disease.

scholarly journals Risk factors of coronary heart disease in children and young adults with parental history of premature coronary heart disease

2016 ◽  
Vol 43 (2) ◽  
pp. 51
Author(s):  
Murti Andriastuti ◽  
Sudigdo Sastroasmoro ◽  
Agus Firmansyah
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Young Adults ◽  
Heart Disease ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Parental History ◽  
Passive Smoker ◽  
History Of ◽  
Children And Young Adults

Background Morbidity and mortality of coronary heart disease(CHD) are recently increasing. This is related to changes in lifestyle,such as lack of activity and high consumption of fatty diet. Themain cause of CHD is atherosclerosis. The development of ath-erosclerosis takes a long time, is asymptomatic, and might beginin childhood. The important risk factors that have roles in increas-ing the likelihood of atherosclerosis are family history of prematureCHD, hypertension, hyperlipidemia, obesity, smoking and irregu-lar activity.Objective The aim of this study was to find out the prevalence ofCHD risk factors in children and young adults who had parentalhistory of premature CHD.Methods This was a descriptive cross sectional study conductedon offspring of premature CHD patients who were admitted in theintensive cardiology care unit (ICCU) of Cipto MangunkusumoHospital between January 1999 to December 2001 and of prema-ture CHD patients who visited the Cardiology Clinic of the Depart-ment of Internal Medicine, Cipto Mangunkusumo Hospital duringMarch and April 2002. Subjects were aged 12 to 25 year-old.Results Among the subjects, 40% had hyperlipidemia, 8% hadhypertension, 11% were obese, 21% were active smokers, 41%were passive smokers, and 73% had irregular activity. Ninety-sevenpercents subjects had more than 1 risk factors.Conclusions The prevalence of hyperlipidemia, hypertension,obesity, passive smoker, active smoker and irregular activity inchildren and young adults with parental history of premature CHDin this study were higher than those in the normal population.Most had more than 1 risk factor, increasing the likelihood of CHD.A screening test should be performed on children with parentalhistory of premature CHD so that early preventive measures mightbe done to minimize the risk factors

scholarly journals Coronary heart disease, hypertension and use of biomass fuel among women: comparative cross-sectional study

BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e030881 ◽  
Author(s):  
Zafar Fatmi ◽  
Georgia Ntani ◽  
David Coggon
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Heart Attack ◽  
Comparison Group ◽  
Cross Sectional Study ◽  
Biomass Fuel ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of

ObjectivesTo explore the associations of hypertension and coronary heart disease (CHD) with use of biomass fuel for cooking.DesignComparative cross-sectional study.SettingRural villages in Sindh, Pakistan.ParticipantsWomen aged ≥40 years who had used biomass fuel for cooking for at least the last year (n=436), and a comparison group (n=414) who had cooked only with non-biomass fuel during the last year were recruited through door-to-door visits. None of those who were invited to take part declined.Primary and secondary outcome measuresHypertension was determined from blood pressure measurements and use of medication. CHD was assessed by three measures: history of angina (Rose angina questionnaire), previous history of ‘heart attack’, and definite or probable changes of CHD on ECG. Potentially confounding risk factors were ascertained by questionnaire and anthropometry. Associations of hypertension and CHD with use of biomass and other risk factors were assessed by logistic regression, and summarised by ORs with 95% CIs.ResultsAfter adjustment for potential confounders, there was no association of hypertension (OR: 1.0, 95% CI 0.8 to 1.4) angina (OR: 1.0, 95% CI 0.8 to 1.4), heart attack (OR: 1.2, 95% 0.7 to 2.2) or ECG changes of CHD (OR: 0.8, 95% CI 0.6 to 1.2) with current use of biomass for cooking. Nor were any associations apparent when analyses were restricted to long-term (≥10 years) users and non-users of biomass fuel.ConclusionsA linked air monitoring study indicated substantially higher airborne concentrations of fine particulate matter in kitchens where biomass was used for cooking. It is possible that associations with CHD and hypertension were missed because most of the comparison group had used biomass for cooking at some time in the past, and risk remains elevated for many years after last exposure.

The Joint Impact of Family History of Myocardial Infarction and Other Risk Factors on 12-year Coronary Heart Disease Mortality

Epidemiology ◽  
1999 ◽  
Vol 10 (6) ◽  
pp. 767-770 ◽  
Author(s):  
Jolanda M. A. Boer ◽  
Edith J. M. Feskens ◽  
W. M. Monique Verschuren ◽  
Jacob C. Seidell ◽  
Daan Kromhout
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Family History ◽  
Coronary Heart Disease Mortality ◽  
Disease Mortality ◽  
History Of

scholarly journals Levels of Prebeta‐1 High‐Density Lipoprotein Are a Strong Independent Positive Risk Factor for Coronary Heart Disease and Myocardial Infarction: A Meta‐Analysis

2021 ◽  
Author(s):  
Clive R. Pullinger ◽  
Patricia M. O’Connor ◽  
Josefina M. Naya‐Vigne ◽  
Steven T. Kunitake ◽  
Irina Movsesyan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
High Density Lipoprotein ◽  
Meta Analysis ◽  
Density Lipoprotein ◽  
High Density ◽  
Odds Ratios ◽  
History Of

Background We previously showed that levels of prebeta‐1 high‐density lipoprotein (HDL), the principal acceptor of cholesterol effluxed from cells, including artery wall macrophages, are positively associated with coronary heart disease (CHD) and myocardial infarction (MI) risk. Methods and Results In a multiethnic follow‐up cohort of 1249 individuals from University of California–San Francisco clinics, we determined the degree to which prebeta‐1 HDL levels, both absolute and percentage of apolipoprotein AI, are associated with CHD and history of MI. Independent, strong, positive associations were found. Meta‐analysis revealed for the absolute prebeta‐1 HDL for the top tertile versus the lowest, unadjusted odds ratios of 1.90 (95% CI, 1.40–2.58) for CHD and 1.79 (95% CI, 1.35–2.36) for MI. For CHD, adjusting for established risk factors, the top versus bottom tertiles, quintiles, and deciles yielded sizable odds ratios of 2.37 (95% CI, 1.74–3.25, P <0.001), 3.20 (95% CI, 2.07–4.94, P <0.001), and 4.00 (95% CI, 2.11–7.58, P <0.001), respectively. Men and women were analyzed separately in a combined data set of 2507 individuals. The odds ratios for CHD and MI risk were similar. Higher levels of prebeta‐1 HDL were associated with all 5 metabolic syndrome features. Addition of prebeta‐1 HDL to these 5 features resulted in significant improvements in risk‐prediction models. Conclusions Analysis of 2507 subjects showed conclusively that levels of prebeta‐1 HDL are strongly associated with a history of CHD or MI, independently of traditional risk factors. Addition of prebeta‐1 HDL can significantly improve clinical assessment of risk of CHD and MI.

scholarly journals Dynamic monitoring of cardiovascular diseases in patients with diabetes mellitus according to mobile medical center (Diamodule) in the regions of Russia

2020 ◽  
Vol 22 (10) ◽  
pp. 39-44
Author(s):  
Anna V. Zheleznyakova ◽  
◽  
Olga K. Vikulova ◽  
Alexey A. Serkov ◽  
Polina A. Alferova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Myocardial Infarction ◽  
Body Mass Index ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Glomerular Filtration Rate ◽  
Cardiovascular Diseases ◽  
Filtration Rate ◽  
Medical Center ◽  
Dynamic Monitoring

Background. Diabetes mellitus (DM) is a powerful factor in the development and progression of cardiovascular diseases (CVD), it produces poor prognosis, in-cluding disability and premature mortality in this category of patients. Aim. To carry out dynamic monitoring of the prevalence of CVD in adult DM patients with type 1 and type 2 (coronary heart disease, myocardial infarction, ce-rebrovascular diseases and arterial hypertension) based on a comprehensive examination in a mobile medical center (Diamodule) with repeated visits to the re-gions in 2019 compared to data of the Federal Program "Diabetes mellitus" (2005–2006). Materials and methods. The object of the study: adult patients with DM1 and DM2 (≥18 years old) who underwent examination in Diamodule (n=1480): 882 patients were in 2005/2006 (337 with DM1 and 545 with DM2) and 598 were in 2019 (275 with DM1 and 323 with DM2). Examination at the medical center in-cludes: assessment of anthropometric data (height, weight, body mass index), biochemical data of blood lipids and creatinine levels with calculation of glomerular filtration rate, measurement of glycated hemoglobin (HbA1c), blood pressure, ECG, cardiologist’s consultation with an assessment of the anamnesis data, la-boratory data, ECG. Results. Over the past 13–14 year period in both types of DM, the prevalence of coronary heart disease significantly decreased: in DM1 by 4,42% by 2 times (p=0,037), in DM2 by 18,34% by 2,7 times (p<0,001); myocardial infarction in DM1 by 1,97% by 1,9 times (p=0,172), in DM2 by 3,28% by 1,5 times (p=0,1); cerebrovascular diseases in DM1 by 2,17% by 3 times (p=0,074), in DM2 by 1,45% by 1,2 times (p=0,44). There was an improvement in the diagnosis of arterial hypertension compared to 2005/2006: in DM1 by 6,4% from 44,5 to 51% (p=0,115), in DM2 by 3,6% from 86,8 to 90,4% (p=0,096). It was revealed that the incidence of CVD with active screening in Diamodule is higher than the recorded data on referral compared with the data of the DM register. DM1 patients in the 2019 were significantly older (39 vs 38 years), with a shorter DM duration (18 vs 25 years), with a better HbA1c level (8,7 vs 9,1%). DM2 patients in the 2019 were significantly older (66 vs 58 years), differed in age of diabetes onset (52 vs 51 years), longer duration of DM2 (14 vs 7 years), lower glomerular filtration rate (54 vs 90,6 ml/min/1,73 m2), they had better level of total cholesterol (4,6 vs 5,1 mmol/L), triglycerides (1,3 vs 2,1 mmol/L), while they did not differ in the level of HbA1c and body mass index. Conclusions. The analysis showed a significant decrease in the prevalence of CVD in DM patients compared with the data obtained in the period 2005–2006, this is the result of CVD prevention programs and improving the quality of medical care for this category of patients.

CARDIOVASCULAR RISK FACTORS PECULIARITIES IN MEN UNDER 60 YEARS OLD WITH MYOCARDIAL INFARCTION AND CHRONIC INFLAMMATORY LUNG DISEASES

2020 ◽  
pp. 21-25
Author(s):  
Tupitsyn V.V. ◽  
Bataev Kh.M. ◽  
Men’shikova A.N. ◽  
Godina Z.N.
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Digestive System ◽  
Control Group ◽  
Study Group ◽  
Type I ◽  
Internal Organs ◽  
History Of

Relevance. Information about the cardiovascular diseases risk factors (CVD RF) for in men with chronic lung inflam-matory pathology (CLID) is contradictory and requires clarification. Aim. To evaluate the peculiarities of CVD RF in men under 60 years of age with CLID in myocardial infarction (MI) to improve prevention. Material and methods. The study included men aged 19-60 years old with type I myocardial infarction. Patients are divided into two age-comparable groups: I - the study group, with CLID - 142 patients; II - control, without it - 424 patients. A comparative analysis of the frequency of observation of the main and additional cardiovascular risk fac-tors in groups was performed. Results. In patients of the study group, more often than in the control group we observed: hereditary burden of is-chemic heart disease (40.8 and 31.6%, respectively; p = 0.0461) and arterial hypertension (54.2 and 44.6%; p = 0.0461), frequent colds (24.6 and 12.0%; p = 0.0003), a history of extrasystoles (19.7 and 12.7%; p = 0.04); chronic foci of infections of internal organs (75.4 and 29.5%; p˂0.0001), non-ulcer lesions of the digestive system (26.1 and 14.6%; p = 0.007), smoking (95.1 and 66.3%; p˂0.0001), MI in winter (40.8 and 25.9%; p = 0.006). Less commonly were observed: oral cavity infections (9.2 and 23.6%; p˂0.0001); hypodynamia (74.5 and 82.5%; p = 0.0358), over-weight (44.4 and 55.2%; p = 0.0136), a subjective relationship between the worsening of the course of coronary heart disease and the season of the year (43.7 and 55.2%; p = 0.0173) and MI - in the autumn (14.1 and 21.9%; p = 0.006) period. Conclusions. The structure of CVD RF in men under 60 years of age with CLID with MI is characterized by the pre-dominance of smoking, non-ulcer pathology of the digestive system, frequent pro-student diseases, meteorological dependence, a history of cardiac arrhythmias and foci of internal organ infections. It is advisable to use the listed factors when planning preventive measures in such patients.

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