scholarly journals Application of Machine Learning and Deep Learning Methods for Brain Tumor Identification and Classification

2020 ◽  
Vol 8 (6) ◽  
pp. 2886-2891

In the area of medical imaging technology, advances in Artificial intelligence (AI) delivers promising solutions with higher accuracy. For healthcare solutions, medical images provides a systematic way for diagnosis the diseases earlier and make treatments more effective. Machine learning and deep learning are rapidly grown fields of AI that may apply to many domains including image processing, speech recognition and text understanding. As MRI image segmentation is a key task for identification of brain anomalies, a fast and reliable technique is essential for increasing the survival ratio of affected patients. Manual segmentation of the brain MRI image involves more time and it may subject to inaccuracies. Hence, AI approaches and algorithms have been developed for tumor segmentation. This paper contains the detailed study of the available methods of machine learning and deep learning for brain tumor identification and classification through MRI image segmentation. It discusses and summarizes the methodologies and its results available for classification of brain tumor.

2021 ◽  
Author(s):  
Shidong Li ◽  
Jianwei Liu ◽  
Zhanjie Song

Abstract Since magnetic resonance imaging (MRI) has superior soft tissue contrast, contouring (brain) tumor accurately by MRI images is essential in medical image processing. Segmenting tumor accurately is immensely challenging, since tumor and normal tissues are often inextricably intertwined in the brain. It is also extremely time consuming manually. Late deep learning techniques start to show reasonable success in brain tumor segmentation automatically. The purpose of this study is to develop a new region-ofinterest-aided (ROI-aided) deep learning technique for automatic brain tumor MRI segmentation. The method consists of two major steps. Step one is to use a 2D network with U-Net architecture to localize the tumor ROI, which is to reduce the impact of normal tissue’s disturbance. Then a 3D U-Net is performed in step 2 for tumor segmentation within identified ROI. The proposed method is validated on MICCAI BraTS 2015 Challenge with 220 high Gliomas grade (HGG) and 54 low Gliomas grade (LGG) patients’ data. The Dice similarity coefficient and the Hausdorff distance between the manual tumor contour and that segmented by the proposed method are 0.876 ±0.068 and 3.594±1.347 mm, respectively. These numbers are indications that our proposed method is an effective ROI-aided deep learning strategy for brain MRI tumor segmentation, and a valid and useful tool in medical image processing.


Author(s):  
Padmapriya Thiyagarajan ◽  
Sriramakrishnan Padmanaban ◽  
Kalaiselvi Thiruvenkadam ◽  
Somasundaram Karuppanagounder

Background: Among the brain-related diseases, brain tumor segmentation on magnetic resonance imaging (MRI) scans is one of the highly focused research domains in the medical community. Brain tumor segmentation is a very challenging task due to its asymmetric form and uncertain boundaries. This process segregates the tumor region into the active tumor, necrosis and edema from normal brain tissues such as white matter (WM), grey matter (GM), and cerebrospinal fluid (CSF). Introduction: The proposed paper analyzed the advancement of brain tumor segmentation from conventional image processing techniques, to deep learning through machine learning on MRI of human head scans. Method: State-of-the-art methods of these three techniques are investigated, and the merits and demerits are discussed. Results: The prime motivation of the paper is to instigate the young researchers towards the development of efficient brain tumor segmentation techniques using conventional and recent technologies. Conclusion: The proposed analysis concluded that the conventional and machine learning methods were mostly applied for brain tumor detection, whereas deep learning methods were good at tumor substructures segmentation.


2021 ◽  
Vol 23 (09) ◽  
pp. 981-993
Author(s):  
T. Balamurugan ◽  
◽  
E. Gnanamanoharan ◽  

Brain tumor segmentation is a challenging task in the medical diagnosis. The primary aim of brain tumor segmentation is to produce precise characterizations of brain tumor areas using adequately placed masks. Deep learning techniques have shown great promise in recent years for solving various computer vision problems such as object detection, image classification, and semantic segmentation. Numerous deep learning-based approaches have been implemented to achieve excellent system performance in brain tumor segmentation. This article aims to comprehensively study the recently developed brain tumor segmentation technology based on deep learning in light of the most advanced technology and its performance. A genetic algorithm based on fuzzy C-means (FCM-GA) was used in this study to segment tumor regions from brain images. The input image is scaled to 256×256 during the preprocessing stage. FCM-GA segmented a preprocessed MRI image. This is a versatile advanced machine learning (ML) technique for locating objects in large datasets. The segmented image is then subjected to hybrid feature extraction (HFE) to improve the feature subset. To obtain the best feature value, Kernel Nearest Neighbor with a genetic algorithm (KNN-GA) is used in the feature selection process. The best feature value is fed into the RESNET classifier, which divides the MRI image into meningioma, glioma, and pituitary gland regions. Real-time data sets are used to validate the performance of the proposed hybrid method. The proposed method improves average classification accuracy by 7.99 % to existing Convolutional Neural Networks (CNN) and Support Vector Machines (SVM) classification algorithms


2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii153-ii154
Author(s):  
Satoshi Takahashi ◽  
Masamichi Takahashi ◽  
Manabu Kinoshita ◽  
Mototaka Miyake ◽  
Risa Kawaguchi ◽  
...  

Abstract BACKGROUND Manual segmentation of brain tumor images from a large volume of MR images generated in clinical routines is difficult and time-consuming. Hence, it is imperative to develop a machine learning model for automated segmentation of brain tumor images. PURPOSE Machine learning models for automated MR image segmentation of gliomas may be useful. However, the image differences among facilities cause performance degradation and impede successful automatic segmentation. In this study, we proposed a method to solve this issue. METHODS We used the data from the Multimodal Brain Tumor Image Segmentation Benchmark (BraTS) and the Japanese cohort (JC) datasets collected from 10 facilities. Three models for tumor segmentation were developed. The BraTS model was trained on the BraTS dataset, and the JC model was trained on the JC dataset; whereas, the Fine-tuning model was a fine-tuned BraTS model using the JC dataset. RESULTS MR images of 544 patients were obtained for the JC dataset. Half of the JC dataset was used for independent testing. The Dice coefficient score of the JC model for the JC dataset was 0.779± 0.137, whereas that of the BraTS model was remarkably lower (0.717 ± 0.207). The mean of the Fine-tuning models for the JC dataset was 0.769 ± 0.138. There was a significant difference between the BraTS and JC models (P < 0.0001) and the BraTS and Fine-tuning models (P = 0.002); however, no significant difference was observed between the JC and Fine-tuning models (P = 0.673). CONCLUSIONS Application of the BraTS model to heterogeneous datasets can significantly reduce its performance; however, fine-tuning can solve this issue. Since our fine-tuning method only requires less than 20 cases, this methodology is particularly useful for a facility where there are a few glioma cases.


Author(s):  
Otman Basir ◽  
Kalifa Shantta

Image segmentation plays a crucial role in recognizing image signification for checking and mining medical image records. Brain tumor segmentation is a complicated assignment in medical image analysis. It is challenging to identify precisely and extract that a portion of the image has abnormal tissues for further diagnosis and analysis. The method of segmenting a tumor from a brain MRI image is a highly concentrated medical science community field, as MRI is non-invasive. In this survey, brain MRI images' latest brain tumor segmentation techniques are addressed a thoroughgoing literature review. Besides, surveys the several approved techniques regularly applied for brain tumor MRI segmentation. Also, highlighting variances among them and reviews their abilities, pros, and weaknesses. Various approaches to image segmentation are described and explicated with the modern participation of several investigators.


2020 ◽  
Author(s):  
Aswani K ◽  
Menaka D

Abstract IntroductionThe brain tumor is the growth of abnormal cells inside the brain. These cells can be grown into malignant or benign tumors. Segmentation of tumor from MRI images using image processing techniques started decades back. Image processing based brain tumor segmentation can be divided in to three categories conventional image processing methods, Machine Learning methods and Deep Learning methods. Conventional methods lacks the accuracy in segmentation due to complex spatial variation of tumor. Machine Learning methods stand as a good alternative to conventional methods. Methods like SVM, KNN, Fuzzy and a combination of either of these provide good accuracy with reasonable processing speed. The difficulty in processing the various feature extraction methods and maintain accuracy as per the medical standards still exist as a limitation for machine learning methods. In Deep Learning features are extracted automatically in various stages of the network and maintain accuracy as per the medical standards. Huge database requirement and high computational time is still poses a problem for deep learning. MethodTo overcome the limitations specified above we propose an unsupervised dual autoencoder with latent space optimization here. The model require only normal MRI images for its training thus reducing the huge tumor database requirement. With a set of normal class data, an autoencoder can reproduce the feature vector into an output layer. This trained autoencoder works well with normal data while it fails to reproduce an anomaly to the output layer. But a classical autoencoder suffer due to poor latent space optimization. The Latent space loss of classical autoencoder is reduced using an auxiliary encoder along with the feature optimization based on Singular value Decomposition (SVD). The patches used for training are not traditional square patches but we took both horizontal and vertical patches to keep both local and global appearance features on the training set. An Autoencoder is applied separately for learning both horizontal and vertical patches. While training a logistic sigmoid transfer function is used for both encoder and decoder parts. SGD optimizer is used for optimization with an initial learning rate of .001 and the maximum epochs used are 4000. The network is trained in MATLAB 2018a with a processor capacity of 3.7 GHz with NVIDIA GPU and 16 GB of RAM.ResultsThe results are obtained using a patch size of 16x64, 64x16 for horizontal and vertical patches respectively. In Glioma images tumor is not grown from a point rather it spreads randomly. Region filling and connectivity operations are performed to get the final tumor segmentation. Overall the method segments Meningioma better than Gliomas. Three evaluation metrics are considered to measure the performance of the proposed system such as Dice Similarity Coefficient (DSC), Positive Predictive Value (PPV), and Sensitivity.ConclusionAn unsupervised method for the segmentation of brain tumor from MRI images is proposed here. The proposed dual autoencoder with SVD based feature optimization reduce the latent space loss in the classical autoencoder. The proposed method have advantages in computational efficiency, no need of huge database requirement and better accuracy than machine learning methods. The method is compared Machine Learning methods Like SVM, KNN and supervised deep learning methods like CNN and commentable results are obtained.


2021 ◽  
Vol 7 (9) ◽  
pp. 179
Author(s):  
Erena Siyoum Biratu ◽  
Friedhelm Schwenker ◽  
Yehualashet Megersa Ayano ◽  
Taye Girma Debelee

A brain Magnetic resonance imaging (MRI) scan of a single individual consists of several slices across the 3D anatomical view. Therefore, manual segmentation of brain tumors from magnetic resonance (MR) images is a challenging and time-consuming task. In addition, an automated brain tumor classification from an MRI scan is non-invasive so that it avoids biopsy and make the diagnosis process safer. Since the beginning of this millennia and late nineties, the effort of the research community to come-up with automatic brain tumor segmentation and classification method has been tremendous. As a result, there are ample literature on the area focusing on segmentation using region growing, traditional machine learning and deep learning methods. Similarly, a number of tasks have been performed in the area of brain tumor classification into their respective histological type, and an impressive performance results have been obtained. Considering state of-the-art methods and their performance, the purpose of this paper is to provide a comprehensive survey of three, recently proposed, major brain tumor segmentation and classification model techniques, namely, region growing, shallow machine learning and deep learning. The established works included in this survey also covers technical aspects such as the strengths and weaknesses of different approaches, pre- and post-processing techniques, feature extraction, datasets, and models’ performance evaluation metrics.


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