CLINICO-DEMOGRAPHIC STUDY OF PATIENTS OF ACANTHOSIS NIGRICANS AT SKMCH, MUZAFFARPUR, BIHAR

2021 ◽  
pp. 45-47
Author(s):  
Barunesh Kishore ◽  
Birendra Prasad ◽  
Debarshi Jana

Aims of the study to evaluate the clinical features and demographic data of acanthosis nigricans and nd out the common disorders associated with acanthosis nigricans. Present study was conducted at Department of Dermatology, Venereology and Leprosy, SKMCH, Muzaffarpur, Bihar. Total 50 patients selected for this study, 47 were female and 3 were male. Most common age group affected with AN in this study is 21- 30 years with 34% patients and another24 % patients were between 11- 20 years and 2% patients were more than 60 years of age. Acanthosis nigricans is a common skin condition which may affect all age group and the list of underlying cause is extensive ranging from a simple benign familial type through syndromic to malignant cause. Clinician should be aware of this and have to nd out the underlying condition and patient should be managed appropriately at the earliest.


2019 ◽  
Vol 8 (9) ◽  
pp. 430-433 ◽  
Author(s):  
Kev Hubbard

This article will provide a general overview of the pathophysiology of acne presentations that may be seen in aesthetic practice, as well as common problems associated with acne. Some of the common treatment modalities that can be used in aesthetic practice will then be discussed. By doing this, the author hopes that aesthetic practitioners will be more confident and more able to manage clients with this potentially debilitating condition.



2019 ◽  
Vol 49 (1) ◽  
pp. 41-42 ◽  
Author(s):  
Hardeep Galsinh ◽  
Kanwaljit Singh ◽  
Lisa Smith


2021 ◽  
Vol 14 (1) ◽  
pp. 50-53
Author(s):  
Madan Prasad Baral ◽  
Nuwadatta Subedi

Background: Autopsy examination is mandatory in all unnatural deaths as per law of Nepal and thus all deaths due to drowning are undergone medico legal autopsy. This study aims to analyze the demographic and autopsy characteristics of drowning deaths in cases brought for medico legal autopsy at a major autopsy center of Gandaki province of Nepal. Methods: This study was conducted based on review of database in a period of two years among 53 corpses of drowning related deaths. The demographic data and relevant information from the inquest and autopsy report of such cases were collected and presented. Result: The commonest age group involved in drowning deaths was <20 years, attributing to 22 (41.5%) cases, and with males (41, 77.4%) more common than females. Suicidal drowning (34, 64.2%) was the commonest manner. Maximum (19, 35.8%) deaths occurred in the rainy season and on lakes (34, 64.1%). Conclusion: Drowning deaths were more common among males of young age groups. Most of the drownings occurred during the rainy season, lakes were the common sites of drowning, and the commonest manner was suicidal.



2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Ni Luh Putu Ratih Vibriyanti Karna ◽  
Dewi Gotama ◽  
Sissy Sissy

Introduction: Pyodermas are infections in the epidermis, just below the stratum corneum or in hair follicles. It is most common in children, although it can also affect adults. Pyoderma often found in tropic areas. Pyoderma is caused by Staphylococcus, Streptococcus, or both. This study aimed to identify the profile of pyoderma in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Method: Study design using descriptive retrospective model, done by taking data from daily visit record in Dermatology Outpatient Department at Sanglah General Hospital Denpasar Periods January 2016 – December 2017.Result: Pyodermas is one of the common skin problems observed in patients attending dermatology OPD. The number of new cases in pyoderma is 202 cases (7,32%), often found in males and 0-5 years age group (35,64%). The diagnosis of furuncle is the most finding type of pyoderma and the most commonly given therapy is a combination therapy of systemic antibiotics with topical. Co-amoxiclav is the most common drug that uses orally and fusidic acid as topical ointment.Conclusion: pyoderma remains as the most common skin infection in dermatology outpatient department at Sanglah General Hospital, Bali-Indonesia.



2020 ◽  
pp. 1-3
Author(s):  
Satpal Yadav ◽  
Aman Goyal ◽  
Poonam Verma

BACKGROUND: Diabetes is most common endocrine disorder with increasing prevalence worldwide. Every organs system is affected by it albeit at different pace. This study was carried out with the aim of studying cutaneous manifestation of diabetes mellitus. METHODS- 200 cases of diabetes mellitus with cutaneous manifestations attending out patient department of dermatology were included in the study. RESULTS - The common skin disorders were cutaneous infections (53.5%), acanthosis nigricans (10.5%), generalized pruritus (10.5%),skintags (9.5%). CONCLUSION - most common dermatological manifestations were cutaneous infections.



2013 ◽  
Vol 7 (08) ◽  
pp. 614-617 ◽  
Author(s):  
Pouran Layegh ◽  
Toktam Moghiman ◽  
Seyed Amir Ahmadian Hoseini

Introduction: Mashhad, located in north-east Iran, is one of the most important regions for cutaneous leishmaniasis (CL) due to Leishmania tropica. Children account for 7-10% of the infected population in the endemic areas. Despite the high sensitivity and susceptibility of this age group, no comprehensive study has yet investigated the clinical characteristics and demographic data in children in our region. Therefore, we aimed to study the clinical features and demographic information in children visiting the Leishmania clinic of two main teaching hospitals. Methodology: In a cross-sectional study all the required data were gathered from the children’s records available at the cutaneous leishmaniasis clinics of Ghaem and Imam Reza hospitals during October 2008 to September 2011. Data included the patient’s age, sex, lesion chronicity and distribution, the clinical features, and the involved body parts. Descriptive statistical tests and SPSS version 11.5 were used for data analyses. Results: Among the 8,801 studied files, 689 (7%) were related to children under the age of 13. Female to male ratio was 0.9 with the highest prevalence in the 6-9 year age group. Regarding disease chronicity, the most common types were acute cases with a 71% prevalence rate. The face was the most involved body part (77.2%) and papules with 37% prevalence were the most common type of lesions seen. Conclusion: Childhood cutaneous leishmaniasis accounts for a major portion of CL in north-east Iran, has no apparent sex preference, and its clinical spectrum does not remarkably differ from that of adult CL.



2018 ◽  
Vol 16 (1) ◽  
pp. 45-48
Author(s):  
Niraj Parajuli ◽  
Bhasker Mohan Meher Kayastha

Introduction: Acne vulgaris is a self-limited disorder of the pilosebaceous unit. It is primarily seen in adolescent age group. Acne can present with pleomorphic lesions consisting of comedones, papules, pustules and nodules. Both inflammatory and non-inflammatory acne can produce scarring. It has been found that acne significantly affects self-image and quality of life. Effective treatment results in improvement of quality of life.Objective: The objective of this study was to find the impairment of quality of life in patients with acne.Materials and Methods: A total of 140 randomly selected patients coming to Dermatology OPD of Bir Hospital with complaints of acne were enrolled. A standard Dermatology Life Quality Index (DLQI) and Cardiff Acne Disability Index (CADI) questionnaires were used.Results: The average score of DLQI in my study was 9.5±5.6 with a minimum score of 0 and maximum score of 25. Similarly, the mean CADI score was 5.9±2.88 with minimum score of 0 and maximum score of 12. This study found acne to be more common in females as compared to males. Most common age group for acne was 16-20 years. Almost half of the patients (46%) complained of flare-ups during summer season. Similarly, majority (60%) of patients could relate to some aggravating factors. Most common aggravating factors were topical medications, fatty foods and stress.Conclusion: Acne is a common skin condition among the adolescents. This study conducted in Dermatology and Venereology Department of Bir Hospital showed that there is invariably some impairment in quality of life in acne patient.



mSphere ◽  
2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Emma Barnard ◽  
Tremylla Johnson ◽  
Tracy Ngo ◽  
Uma Arora ◽  
Gunilla Leuterio ◽  
...  

ABSTRACT Porphyrins are intermediate metabolites in the biosynthesis of vital molecules, including heme, cobalamin, and chlorophyll. Bacterial porphyrins are known to be proinflammatory, with high levels linked to inflammatory skin diseases. Propionibacterium species are dominant skin commensals and play essential roles in defending against pathogens and in triggering an inflammatory response. To better understand how the inflammatory potential of the skin microbiome may vary depending on its propionibacterial composition, we compared the production levels of porphyrins among Propionibacterium acnes, Propionibacterium granulosum, Propionibacterium avidum, and Propionibacterium humerusii strains. We found that porphyrin production varied among these species, with P. acnes type I strains producing significantly larger amounts of porphyrins than P. acnes type II and III strains and other Propionibacterium species. P. acnes strains that are highly associated with the common skin condition acne vulgaris responded to vitamin B12 supplementation with significantly higher porphyrin production. In contrast, vitamin B12 supplementation had no effect on the porphyrin production of health-associated P. acnes strains and other propionibacteria. We observed low-level porphyrin production in most Propionibacterium strains harboring the deoR repressor gene, with the exception of P. acnes strains belonging to type I clades IB-3 and IC. Our findings shed light on the proinflammatory potential of distinct phylogenetic lineages of P. acnes as well as other resident skin propionibacteria. We demonstrate that the overall species and strain composition is important in determining the metabolic output of the skin microbiome in health and disease. IMPORTANCE Porphyrins are a group of metabolites essential to the biosynthesis of heme, cobalamin, and chlorophyll in living organisms. Bacterial porphyrins can be proinflammatory, with high levels linked to human inflammatory diseases, including the common skin condition acne vulgaris. Propionibacteria are among the most abundant skin bacteria. Variations in propionibacteria composition on the skin may lead to different porphyrin levels and inflammatory potentials. This study characterized porphyrin production in all lineages of Propionibacterium acnes, the most dominant skin Propionibacterium, and other resident skin propionibacteria, including P. granulosum, P. avidum, and P. humerusii. We revealed that P. acnes type I strains produced significantly more porphyrins than did type II and III strains and other Propionibacterium species. The findings from this study shed light on the proinflammatory potential of the skin microbiome and can be used to guide the development of effective acne treatments by modulating the skin microbiome and its metabolic activities.



2019 ◽  
Author(s):  
Waheed Atilade Adegbiji ◽  
Shuaib Kayode Aremu ◽  
AbdulAkeem Adebayo Aluko

BACKGROUND Issues of geriatric otolaryngologic emergency have not been widely applied despite increase in geriatric population. OBJECTIVE This study aimed at determining prevalence, sociodemographic features, aetiology, clinical features, Complications and sources ofreferral of geriatric otorhinolaryngological, head and neck emergency in our center. METHODS This was a prospective hospital based study of geriatric otorhinolaryngology emergency in the Ear, Nose and Throat Department of Ekiti State University Teaching Hospital. The study was carried out between October 2016 and September 2018. Data were obtained by using pretested interviewers questionnaire.All data were collated and analyzed using SPSS version 18.0. The data were expressed by frequency table, percentage, bar charts and pie charts. RESULTS Geriatric otorhinolaryngology, head and neck emergency accounted for 5.3%. Major prevalence age group was 43.9% in the age group (60-64). There were 38.6% males with male to female ratio of 1:1.5. The main aetiology of geriatric otorhinolaryngology emergency was 29.5% trauma/road traffic accident/foreign body impaction and 25.8% tumour. Main anatomical distribution of geriatric otorhinolaryngology emergency were 38.6% throat diseases and 31.1% ear diseases. The most frequent clinical features were pain in 27.3%, hearing loss in 21.2%, tinnitus in 15.9%, bleeding in 14.4%, difficulty breathing in 12.9% and discharge in 11.4%. Common diagnosis in this study were 15.9% sinonasal tumour, 14.4% upper aerodigestive foreign body impaction, 10.6% earwax impaction and 19.8% otitis externa. Acute presentation (<13 weeks) occurred in 1 week in 74.2% and 2-13 weeks In 19.7%. Commonest time of presentation was daytime in 65.9%. Major sources of referral were 43.2% general practitioner and 31.1% casualty officers. Presentation of geriatric otorhinolaryngology emergency were mainly ear, nose and throat clinic in 59.8% with accident and emergency in 28.8%. Commonest associated comorbid illnesses among the geriatric patients were 18.2% hypertension, 14.4% arthritis and 9.8% diabetes mellitus. CONCLUSIONS Geriatric otorhinolaryngological emergency are common pathology with associated with comorbid illnesses. Detailed clinical assessment are mandatory for effective management outcome.



2014 ◽  
Vol 34 (2) ◽  
pp. 100-103 ◽  
Author(s):  
Ajaya Kumar Dhakal ◽  
D Shrestha ◽  
A Shakya ◽  
SC Shah ◽  
H Shakya

Introduction: Acute poisonings are one of the common cause of emergency visits and hospital admissions and is potentially preventable cause of childhood mortality and morbidity. The objectives of this study were to identify the common type of poisoning in children, to determine types of poisoning according to age and to find out the common age group in which the incidence of poisoning was high.Materials and Methods: It was a descriptive observational study done in a teaching hospital in Lalitpur, Nepal in patients aged 1 month to 18 years who visited the emergency department and were admitted to hospital with history of alleged poisoning from 2009 July to 2014 January.Results: Fifty patients were included. Drugs, kerosene and organophosphorus were most common cause of poisoning. Drugs and kerosene below 10 years of age and organophosphorus and drugs above 10 years of age were common types of poisoning. Maximum numbers (50%) of children with poisoning cases were below five year of age. Mean duration of hospital stay was 2.1days and mean age of poisoning was 7.8 years with a male(54%) predominance. Majority of poisoning occurred at home (84%) and 68% of patients were symptomatic at presentation to hospital with 84% of patients presenting to hospital within six hours.Conclusion: This study showed that drugs, kerosene and organophosphorus were most common forms of poisoning. Young children were most vulnerable for acute poisoning.DOI: http://dx.doi.org/10.3126/jnps.v34i2.10139J Nepal Paediatr Soc 2014;34(2):100-103 



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