“THE STUDY TO ASSESS AN INCIDENCE OF FEVER IN POST-OPERATIVE PATIENTS ADMITTED IN SURGICAL ICU AT NATIONAL CANCER INSTITUTE, DHARAMPETH, NAGPUR.”

2021 ◽  
pp. 97-98
Author(s):  
Payal R. Burbure
Keyword(s):  
National Cancer Institute ◽  
Fisher Exact Test ◽  
Test Statistic ◽  
Postoperative Fever ◽  
Exact Test ◽  
Descriptive Research ◽  
Common Causes ◽  
Surgical Icu ◽  
The Common ◽  
Wbc Count

INTRODUCTION: Postoperative fever is one of the most common problems seen in the postoperative ward. Most cases of fever immediately following surgery are self-limiting. The appearance of postoperative fever is not limited to specic types of surgery. Fever can occur immediately after surgery and seen to be related directly to the operation or may occur sometime after the surgery as a result of an infection at the surgical site or infections that involve organs distant from the surgery. Objectives: To study the common causes of post operative fever in general surgery patients. To study the correlation between the cause and the day of onset of fever. To study the risk factors associated with post operative fever. Material and Method: In this study Descriptive Research Design was used. The samples were 30 Post operative patients which fulls inclusion criteria. Setting of the study was surgical ICU, National cancer Institute, Dharampeth, Nagpur. RESULTS:-The result of this study shows that There 6 patients in the age group of 41yrs to 60 yrs having increase WBC count. Fisher exact test statistic value is 0.0449. The result is signicant at p < .05. so the post operative fever is signicantly associated with gender of the patient, Types of surgery and increase WBC count in Patient.

scholarly journals MUTU PELAYANAN GIZI DENGAN TINGKAT KEPUASAN PASIEN

2018 ◽  
Vol 7 (2) ◽  
Author(s):  
Iin Rachmawati ◽  
Wiwik Afridah
Keyword(s):  
Significant Relationship ◽  
Fisher Exact Test ◽  
Hospital Service ◽  
Test Statistic ◽  
Cross Sectional ◽  
Exact Test ◽  
Patient’S Satisfaction ◽  
Independent Variable ◽  
The Relationship

The quality of nutritional service is one of the indicators of the quality hospital service. Therefore, the purpose of this research was to find out the relationship between the quality of hospital nutritional service and the level of patient’s satisfaction hospitalized in Teratai Room of Islamic Hospital located on Jemursari, Surabaya.The design of research was analytic cross sectional. The population of patient’s hospitalized ≥ 3 days in Teratai Room of Islamic Hospital located on Jemursari, Surabaya by 40 respondents, a sample of 36 respondents, taken using a consecutive sampling.The independent variable was the quality of hospital nutritional service, where as the dependent one was the level of patient’s satisfaction. Instrument using a questionnaire sheet. Analysis of the data by the Fisher Exact Test. The result of research showed that most of the respondent (52,2%) said the quality of nutritional hospital service is good and nearly half (47,2%) said they were satisfied. Fisher’s Exact Test statistic test value obtained ρ = 0.007 describing that there was a significant relationship between the quality of hospital nutritional service and the level of patient’s satisfaction hospitalized in the hospital. The research has concluded that most of the quality nutritional of hospital service is have good and patient’s have satisfaction. The nutritional official must be through, when process and prepare a dish up a food a patient

scholarly journals Age as the Risk Factor that Affected the Increased Degree of Uterine Prolapse

2018 ◽  
Vol 1 (1) ◽  
pp. 20
Author(s):  
Shervil Kagayaita Sayko ◽  
Eighty Mardiyan Kurniawati ◽  
Pudji Lestari
Keyword(s):  
Elderly Women ◽  
Uterine Prolapse ◽  
Fisher Exact Test ◽  
Test Statistic ◽  
Cross Sectional ◽  
Significance Level ◽  
Exact Test ◽  
Significant Difference ◽  
The Relationship

Introduction: Uterine prolapse is a gynecological problem that women often experience with a prevalence of 50% and is predicted that the next 30 years will increase by 45% as life expectancy increases. Increased degrees of uterine prolapse have an impact on the deterioration of women's quality of life. The uterine prolapse is influenced by several mutually supportive factors. The purpose of this study was to analyze the relationship between these factors to the degree of uterine prolapse.Methods: This research is an observational analytic research with cross sectional approach. The number of samples were 65 patients with uterine prolapse at Policlinic Gynecology RSUD Dr. Soetomo Surabaya from 2015-2017. Sampling was done by consecutive sampling. To find out the significant level, the collected data will be tested with Fisher Exact Test statistic at significance level α = 0,05.Results: The result showed that there was significant difference between degree of uterine prolapse with age factor (p = 0,016) and obesity (p = 0,041). As for the parity factor (p = 0.508) there was no significant difference between the parity factor and the degree of uterine prolapse.Discussion: Age is a major factor affecting the degree of uterine prolapse, weakening of pelvic floor tissue and muscle in elderly women is the main cause. While on the obesity factor, there is no data to support that obesity is related to the degree of uterine prolapse because the trend indicates that the majority of patients are not obese. In contrast the parity factor, although according to the statistical test there is no difference to the degree of uterine prolapse, the trend shows that parity leads to increased incidence of uterine prolapse itself.Conclusion: Age is a factor that affects the degree of uterine prolapse.

scholarly journals P919 The correlation between cardiac biomarkers and findings on transthoracic echocardiography in the intensive care unit

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
F O"riordan ◽  
M Carton ◽  
J J Coughlan ◽  
A Fahy ◽  
M Donnelly ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Left Ventricular ◽  
Normal Group ◽  
Cardiac Biomarkers ◽  
Fisher Exact Test ◽  
Continuous Variables ◽  
Test Statistic ◽  
Exact Test ◽  
Abnormal Group

Abstract BACKGROUND Trans-thoracic echo (TTE) is a commonly performed non-invasive investigation for the cardiovascular assessment of critically ill patients in the Intensive Care Unit (ICU). Raised cardiac biomarkers are commonly cited as an indication for TTE, however the significance of these biomarker elevations in the critical care setting is unclear. PURPOSE The aim of this study was to describe findings on TTE in an Irish ICU cohort and to determine if there was any correlation between these findings and serum N-terminal pro b-type natiuretic (NT-proBNP) and high sensitivity troponin T (HsTnT) levels. METHODS Patients admitted to the ICU and who received a TTE between January 2018 and February 2019 were identified. Based on TTE findings, patients were divided into two groups: ‘Normal group’ and ‘Abnormal group’. For the purpose of this study, minor abnormalities including concentric left ventricular hypertrophy, diastolic dysfunction and hyper-dynamic left ventricular function were included in the Normal group. The Abnormal group included reductions in LV function, regional wall motion abnormalities and significant valvular heart disease. Continuous variables were expressed as medians and interquartile range. The groups were compared using the z-test for continuous variables and fishers exact test for categorical variables, with a p value of &lt; 0.05 considered significant. RESULTS There were 358 patients admitted to the ICU during the study period. The mean age was 59.8 ± 17 years and over half of the patients (55%) were male. One hundred and fifteen patients (32%) had a reported TTE, of which 55% were normal and 22% had minor abnormalities (Normal group). The remaining 23% showed significant abnormalities (Abnormal group). The prevalence of a NT-proBNP result over 4 times the upper limit of normal (&gt;4xULN) was not significantly different between groups (67% in Normal group vs 71% in Abnormal group, Fisher exact test statistic value is 0.7887, p &lt; .05). However a HsTnT value &gt;4xULN was more common in the Abnormal group than the Normal group (73% vs 46%, Fisher exact test statistic value is 0.0231, p &lt; .05). Similarly, Median NT-proBNP did not differ significantly between the groups; (2254pg/mL; IQR: 11,758 in the Normal group vs 6428pg/mL; IQR: 5,789 in the Abnormal group, p = 0.52218) but Median HsTnT level was significantly higher in the Abnormal group than Normal group; (123ng/L ; IQR: 656 vs 51ng/L; IQR: 163.5 ,p = 0.0278). CONCLUSION TTE is performed commonly in the ICU, with one-third of ICU admissions receiving a TTE. Over 75% were reported as normal or showing only minor abnormalities. NT-Pro BNP was commonly significantly elevated but did not correlate with the subsequent diagnostic yield of significant abnormalities on echocardiography. HsTnT levels were more commonly significantly raised in patients with abnormal TTE results and the role of troponin in this setting requires further evaluation.

scholarly journals Idh-1 Status and Venous Thromboembolism in Glioma Patients

2019 ◽  
pp. 1-5
Author(s):  
Ahmed Aly ◽  
Fiona Smith ◽  
Laurence J Glancz ◽  
Alistair Mccabe ◽  
Julie Coventry ◽  
...  
Keyword(s):  
P Value ◽  
Fisher Exact Test ◽  
Wild Type ◽  
Isocitrate Dehydrogenase 1 ◽  
Secondary Glioblastoma ◽  
Exact Test ◽  
Ct Angiogram ◽  
Venous Thromboembolic Events ◽  
Common Causes ◽  
Venous Thromboembolic

Background: Venous thromboembolic events (VTE) are common causes of morbidity and mortality in glioblastoma patients. Mutation in the isocitrate dehydrogenase 1 enzyme (IDH1) is frequent in secondary glioblastoma and results in altered metabolomics. Objectives: This study evaluates whether IDH-1 status correlates with incidence of VTE in glioblastoma patients. Methods: Observational study of 398 cases of patients with glioblastoma, who all underwent surgery in a regional Neurosurgical centre between April 2012 and December 2014. IDH -1 status and Tissue factor (F3) protein expression were assessed by immunohistochemistry. Deep venous thrombosis (DVT) and pulmonary embolism (PE) were diagnosed by Doppler ultrasound and pulmonary CT angiogram respectively. Results: 336 cases were wild type (WT) IDH-1 (94.1%) and 21 cases were IDH-1 mutated (R132H) (5.9%). 51 patients had a thromboembolic event (15.3%), with all cases of VTE in WT IDH-1 tumours, a rate of 21.8% within this group. IDH-1 status had a significant correlation with VTE (p=0.033 Fisher exact test). As expected, mutant IDH was associated with prolonged patient survival (p=0.024 Log rank). The mean expression in IDH-1 wild type GBM was 7.14 and in R132h mutant GBM was 4.87 (log2 scale). This was highly statistically significant with a corrected P value of less than 0.0001. Conclusion: A significant association exists between IDH1 status in glioblastoma patients and the risk of VTE. Patients with wild type IDH-1 appear at high risk of VTE and appropriate precautions should be considered

Role of external ventriculostomy in the management of fever after hemispherectomy

2008 ◽  
Vol 2 (6) ◽  
pp. 427-429 ◽  
Author(s):  
Sandeep Sood ◽  
Eishi Asano ◽  
Harry T. Chugani
Keyword(s):  
Body Temperature ◽  
Hospital Stay ◽  
Lower Risk ◽  
Intractable Epilepsy ◽  
Fisher Exact Test ◽  
Common Occurrence ◽  
Postoperative Fever ◽  
Exact Test ◽  
Intractable Seizures

Object Fever is a common occurrence after cerebral hemispherectomy in children and prolongs the hospital stay. The authors determined whether an external ventriculostomy might reduce the incidence of fever following a hemispherectomy. Methods The postoperative courses of 27 patients who had undergone cerebral hemispherectomy for intractable seizures were retrospectively analyzed. Results Thirteen children underwent an external ventriculostomy, and only 1 had an elevated axillary body temperature of ≥ 39°C during the postoperative period. Among 14 patients who did not undergo an external ventriculostomy, 7 had a posthemispherectomy fever of ≥ 39°C. Patients who underwent an external ventriculostomy had a lower risk of postoperative fever compared with those who did not undergo the procedure (8 vs 50%, respectively; p = 0.03, Fisher exact test). None of the patients had an infection accounting for the cause of the fever. The hospital stay for patients who had undergone postoperative external ventriculostomy was significantly shorter than for those who had not (7.2 ± 2 vs 11.3 ± 5 days, respectively; p = 0.01, Student t-test). Conclusions The use of external ventriculostomy following hemispherectomy for intractable epilepsy in children reduces the incidence of postoperative fever due to infection.

Association Of FLT3 Mutations With Unfavorable Factors In AML and APL Patients

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 4967-4967
Author(s):  
Irina Shmunk ◽  
Olga Korobitsyna ◽  
Marina Zakharova ◽  
Mikhail Lyubchenko ◽  
Alexander Korobkin ◽  
...  
Keyword(s):  
Platelet Count ◽  
Tyrosine Kinase ◽  
Conflicts Of Interest ◽  
Point Mutations ◽  
Tyrosine Kinase Domain ◽  
Fisher Exact Test ◽  
Exact Test ◽  
Flt3 Mutations ◽  
Wbc Count ◽  
The Impact

Abstract Background Mutations in the fms-like tyrosine kinase 3 (FLT3) gene have been considered to predict a poor prognosis in acute myeloid leukemia (AML). Internal tandem duplication (ITD) of the FLT3 is one of the most frequent mutations activating aberrant signal-transduction in AML. The impact of D835 point mutations in tyrosine kinase domain (TKD) on prognosis is less clear. Aims Characterization of AML and APL (acute promyelocytic leukemia) patients with FLT3 mutations. Methods FLT3 status in bone marrow samples of adult patients (pts) with AML (63 pts) (m\28; f\35; median 53 yrs, 19-73 yrs) and APL (14 pts) (m\3; f\11; median 43 yrs, 25-62 yrs) at diagnosis was examined. Genomic PCR amplification of ITD and TKD containing regions of the FLT3 gene was performed. The TKD amplicon product was restricted with the EcoRV enzyme. Results were detected by gel electrophoresis. Results FLT3\ITD was found in 8 AML pts (12.7%) and in 5 APL pts (35.7%), p=0.053 (Fisher Exact test). FLT3\TKD was found in 4 AML pts (6.4%) and in 1 APL pt (7.1%). In AML group there were 1 pt with t(6;9) in FLT3\ITD+ subgroup and 1 pt with inv16 in FLT3\TKD+. There were 1 pt with t(6;11), 1 with dupMLL, 3 with t(8;21), 7 with inv16 in AML pts without FLT3 mutations (FLT3-). There were no significant differences in sex, age, WT1 expression at diagnosis between AML pts with FLT3\ITD, FLT3\TKD and without FLT3 mutations. But the presence of FLT3 mutations was related to high peripheral white blood cell (WBC) count in AML pts at diagnosis. The median value (m) of WBC was 49.2 x109\L (range 2.75-191) in FLT3\ITD+; m= 81 x109\L (range 7.2-153) in FLT3\TKD+; m= 5.4 x109\L (range 0.2-230) in FLT3-. The differences are statistically significant between subgroups with FLT3\ITD+ and FLT3- (p<0.05, Mann–Whitney U test); FLT3\ITD+TKD and FLT3- (p<0.01, Mann–Whitney U test). In FLT3\ITD+TKD subgroup 66.7% of pts had WBC over 30 x109\L, whereas in subgroup without FLT3 mutations only 23.4% of pts had the same unfavorable factor, p=0.012 (Fisher Exact test). In APL group the t(15;17) translocation was detected in 11 pts. 3 pts were without PML\RARa, NPM1\RARa, PLZF\RARa fusions. One FLT3\TKD+ pt had bcr1 PML breakpoint. In FLT3\ITD+ subgroup 4 pts (80%) had bcr3 PML breakpoint, whereas in FLT3- subgroup only 1 pt (12.5%) had bcr3, p=0.032 (Fisher Exact test). In FLT3\ITD+ subgroup all pts had WBC >10 x109\L; moreover, 3 pts (60%) had two unfavorable factors in combination (WBC >10 x109\L plus platelet count < 40 x109\L) at diagnosis, and in FLT3- subgroup nobody had the same combination, p=0.035, (Fisher Exact test). Out of 5 pts with FLT3\ITD 2 ones had death in induction, 1 pt had late molecular remission, 1 had molecular persistence and 1 pt without RARa fusion had failure in WT1 reduction after induction (under 2 log). One FLT3\TKD+ pt had the early relapse. Summary The results confirm previous reports. FLT3\ITD mutations are seen more frequently in APL than in other subtypes of AML. FLT3 mutations in AML have association with such unfavorable prognostic factor as high WBC count at diagnosis. FLT3\ITD in APL associates with bcr3 and with combination of high WBC count plus low platelet count. The presence of FLT3 mutations is related to unfavorable events in APL pts. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Prevalence and serotypes of Shiga toxin-producing Escherichia coli (STEC) in dairy cattle from Northern Portugal

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0244713
Author(s):  
Andressa Ballem ◽  
Soraia Gonçalves ◽  
Isidro Garcia-Meniño ◽  
Saskia C. Flament-Simon ◽  
Jesús E. Blanco ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Shiga Toxin ◽  
Control Strategies ◽  
Virulence Gene ◽  
Fisher Exact Test ◽  
Test Statistic ◽  
Exact Test ◽  
Lactating Cows ◽  
Faecal Samples ◽  
Shiga Toxin 2

The prevalence of Shiga toxin (Stx)-producing Escherichia coli (STEC) was determined by evaluating its presence in faecal samples from 155 heifers, and 254 dairy cows in 21 farms at North of Portugal sampled between December 2017 and June 2019. The prevalence of STEC in heifers (45%) was significantly higher than in lactating cows (16%) (p<0.05, Fisher exact test statistic value is <0.00001). A total of 133 STEC were isolated, 24 (13.8%) carried Shiga-toxin 1 (stx1) genes, 69 (39.7%) carried Shiga-toxin 2 (stx2) genes, and 40 (23%) carried both stx1 and stx2. Intimin (eae) virulence gene was detected in 29 (21.8%) of the isolates. STEC isolates belonged to 72 different O:H serotypes, comprising 40 O serogroups and 23 H types. The most frequent serotypes were O29:H12 (15%) and O113:H21 (5.2%), found in a large number of farms. Two isolates belonged to the highly virulent serotypes associated with human disease O157:H7 and O26:H11. Many other bovine STEC serotypes founded in this work belonged to serotypes previously described as pathogenic to humans. Thus, this study highlights the need for control strategies that can reduce STEC prevalence at the farm level and, thus, prevent food and environmental contamination.

scholarly journals Analysis of the Influence of an Interpersonal Communication Doctors Specialist on Patient Satisfaction in Investigation

2021 ◽  
Vol 8 (1) ◽  
pp. 1-10
Author(s):  
Anggraini Sariputri ◽  
Sri Lestari Ramadhani Nasution ◽  
Ermi Girsang
Keyword(s):  
Patient Satisfaction ◽  
Interpersonal Communication ◽  
Research Data ◽  
Fisher Exact Test ◽  
Hospital Doctor ◽  
Exact Test ◽  
Descriptive Research ◽  
A Value ◽  
Quality Of Health Services

The effective communication that occurs between doctors and patients will create a sense of comfort for the patient with medical therapy given by the doctor when examining the inpatient room of the Royal Prima Hospital, Medan. This paper analyzes the influence of interpersonal communication of specialist doctors on patient satisfaction at Royal Prima Medan Hospital. This type of research is quantitative with a study-descriptive research design. The population in this study were all inpatients at the Royal Prima Medan Hospital. The research sample was 80 hospitalized patients. The analysis of research data was univariate, bivariate, and multivariate analysis. The results of the study with the Fisher Exact test explained that there was a relationship between interpersonal communication of specialist doctors and patient satisfaction with a value of p = 0.002. In this study, it can be concluded that there is an influence between the doctor's interpersonal communication on patient satisfaction in the inpatient room of Royal Prima Medan Hospital. It is recommended for the hospital to improve the quality of health services, especially in terms of interpersonal communication between doctors and patients in the inpatient room. Keywords: interpersonal communication, patient satisfaction, hospital, doctor.

scholarly journals Fetal magnetic resonance imaging in the evaluation of congenital diaphragmatic anomalies

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Harshavardhan Mahalingam ◽  
Biji Babu ◽  
Rajeswaran Rangasami ◽  
Sudarshan Suresh ◽  
Indrani Suresh ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Fetal Mri ◽  
Fisher Exact Test ◽  
Resonance Imaging ◽  
Test Statistic ◽  
Fetal Magnetic Resonance Imaging ◽  
Exact Test ◽  
Fetal Imaging ◽  
Operative Findings

Abstract Background Congenital abnormalities of the diaphragm cause impairment of lung development and are an important cause of post-natal morbidity and mortality. Congenital diaphragmatic eventration (CDE), a less sinister diaphragmatic anomaly compared to the more common congenital diaphragmatic hernia (CDH), often tends to mimic CDH on prenatal imaging. This study evaluates the role of fetal magnetic resonance imaging (MRI) in differentiating these two entities. Results This was a retrospective study which included fetal MRI studies done in patients with ultrasound diagnosis of fetal diaphragmatic anomaly. MRI exam was performed with a 1.5 T superconducting system with eight-element torso array coil. The images were studied by two radiologists experienced in fetal imaging in consensus. Diagnosis of CDE was made if the dome of the diaphragm was visualized as a thin hypointense line separating the lung from abdominal structures on coronal and sagittal MRI sequences. If this thin hypointense line was not visualized, a diagnosis of CDH was made. The findings were then correlated with autopsy/intra-operative findings/post-natal imaging follow-up. A total of 12 patients were included in the study. In these 12 patients, 13 diaphragmatic abnormalities were diagnosed on MRI (1 fetus had bilateral diaphragmatic anomaly). Of the 13 diaphragmatic anomalies detected, 7 (54%) were CDH and 6 (46%) were CDE. The type of diaphragmatic anomaly was correctly identified on MRI in all except one fetus in which CDE was misdiagnosed as CDH. The Fisher exact test statistic value was 0.0047. The result was significant at p < 0.01. Conclusion Fetal MRI is a useful tool for assessing congenital diaphragmatic anomalies. Visualization of the diaphragm on coronal and sagittal images helps in diagnosis of complete CDE and differentiating it from the more sinister CDH.

Venous Thromboembolism and High Grade Gliomas

1993 ◽  
Vol 70 (03) ◽  
pp. 393-396 ◽  
Author(s):  
Mandeep S Dhami ◽  
Robert D Bona ◽  
John A Calogero ◽  
Richard M Hellman
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Medical Center ◽  
Significant Risk ◽  
Bleeding Complications ◽  
Fisher Exact Test ◽  
High Grade ◽  
Chi Square ◽  
Exact Test ◽  
High Grade Gliomas

SummaryA retrospective study was done to determine the incidence of and the risk factors predisposing to clinical venous thromboembolism (VTE) in patients treated for high grade gliomas. Medical records of 68 consecutive patients diagnosed and treated at Saint Francis Hospital and Medical Center from January 1986 to June 1991 were reviewed. The follow up was to time of death or at least 6 months (up to December 1991). All clinically suspected episodes of VTE were confirmed by objective tests. Sixteen episodes of VTE were detected in 13 patients for an overall episode rate of 23.5%. Administration of chemotherapy (p = 0.027, two tailed Fisher exact test) and presence of paresis (p = 0.031, two tailed Fisher exact test) were statistically significant risk factors for the development of VTE. Thrombotic events were more likely to occur in the paretic limb and this difference was statistically significant (p = 0.00049, chi square test, with Yates correction). No major bleeding complications were seen in the nine episodes treated with long term anticoagulation.We conclude that venous thromboembolic complications are frequently encountered in patients being treated for high grade gliomas and the presence of paresis and the administration of chemotherapy increases the risk of such complications.

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