scholarly journals MICROALBUMIN STATUS IN RELATION TO GLYCATED HAEMOGLOBIN AMONG TYPE 2 DIABETES MELLITUS IN SOUTH KERALA POPULATION-A COMPARATIVE STUDY

2020 ◽  
pp. 1-3
Author(s):  
B Shanthi

Diabetes mellitus (DM) is a group of metabolic diseases which if not controlled can cause life threatening complication. The objective of the study is to assess the correlation of urine microalbumin (MAU) with (HbA1C) in type 2 DM patients. Total 180 patients diagnosed for type 2 DM, age 30-60 years were selected and fasting plasma glucose, creatinine,HbA1C and MAU were estimated.HbA1C levels and MAU levels shows significant positive correlation (r = 0.429, p<0.01) and the relationship is significant for all the three age groups. The study concluded that there was an increased prevalence of MAU and high HbA1C level among the patients with type 2 DM, and also highlights that there is a significant correlation betweenMAUlevels andHbA1Cfor allthe three agegroupswhichnecessitatesfor earlydetectionofnephropathyanduncontrolled diabetes.

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Rixi Gahung ◽  
Karel Pandelaki ◽  
Emma Sy. Moeis

Abstract: Diabetes mellitus is still increasing in number in the future. Type 2 diabetes mellitus type 2 (T2DM) often appears in adults and the cause is due to a shortage of the hormone insulin on a relative basis, generally appears slowly and gradually worsens. One of the parameters to control blood sugar level is HbA1c. The high HbA1c increases the risks and complications in T2DM patients. This study aimed to obtain the relationship between HbA1c level and GFR among T2DM patients. This was an analytical study using the patient's medical record data. This study was conducted at the Endocrine Clinic and Heart and Hypertension Clinic with a total samples of 65 patients. The results showed that of the 65 subjects, there were 40 male patients and 25 female patients. The Pearson correlation test showed that the relationship of the HbA1c level and GFR had a p value = 0.05 > 0.462 and the correlation r = 0.093. Conclusion: There was no significant relationship between HbA1c level and GFR in type 2 DM patients. Keywords: HbA1c, GFR, type 2 DM Abtsrak: Diabetes merupakan suatu penyakit tidak menular yang akan terus meningkat jumlahnya di masa datang. Diabetes Melitus tipe 2 (DMT2) sering muncul pada orang dewasa dan penyebabnya oleh karena kekurangan hormon insulin secara relatif , umumnya muncul perlahan dan secara bertahap akan bertambah berat. Salah satu parameter kontrol kadar gula darah ialah HbA1c. Jika HbA1c meningkat terjadi pula peningkatan resiko komplikasi. Penelitian ini bertujuan untuk mengetahui hubungan kadar HbA1c dengan eLFG pada pasien DMT2. Jenis penelitian ini analitik dengan mengevaluasi data rekam medik pasien. Penelitian dilakukan di Poliklinik Endokrin dan Poliklinik Jantung dan Hipertensi dengan jumlah subyek penelitian 65 pasien DMT2. Hasil penelitian ini menunjukkan bahwa dari 65 orang subjek terdapat 40 laki-laki dan 25 perempuan. Untuk mengetahui adanya hubungan kadar HbA1c dengan LFG digunakan analisis bivariat Pearson correlation yang mendapatkan nilai p hitung = 0,462> 0,05 dengan kekuatan korelasi r = 0,093. Simpulan: Tidak terdapat hubungan bermakna antara kadar HbA1c dengan eLFG pada pasien DM tipe 2.Kata kunci: HbA1c, eLFG, DM tipe 2


2021 ◽  
Vol 2 (1) ◽  
pp. 23-28
Author(s):  
Alexander Petra Sihite ◽  
I Gusti Ngurah Pramesemara ◽  
I Wayan Surudarma

Background: Type 2 diabetes mellitus is a metabolic disease that characterized by high blood sugar levels. This condition is often not noticed immediately and usually patient starting to realize it when complications have been occurred. A long-term complication of type 2 DM that occurred in men is erectile dysfunction (ED). ED is a condition when a person is unable to achieve or maintain an erection for sexual intercourse. One factor that influence the occurrence of ED and its severity in type 2 DM patients is the duration of the disease. Objective: The aim of this study was to determine the relationship of type 2 DM duration and the occurrence of ED. Methods: This study is an observational analytic cross-sectional study conducted at the Puskesmas (Public Health Center) Denpasar Barat I. The research data was obtained through medical record data and fill the International Index of Erectile Function (IIEF-5) questionnaire on 36 type 2 DM patients aged around 40-60 years. The statistical analysis used was Fisher's exact test. Results: The results showed that of the 36 samples, 19 (52.8%) samples had type 2 DM <24 months and 17 (47.2%) samples had type 2 DM >24 months. It was found that 5 (13.9%) samples did not experience ED while the rest experienced ED with different severity. There was a significant relationship between the type 2 DM duration and the occurrence of erectile dysfunction at Puskesmas Denpasar Barat I (p = 0.022). Conclusion: Study has found that type 2 DM patients with the longer duration (>24 months)  have a higher occurrence of ED and tended to be more severe compared to those with shorter duration (<24 months). Further studies should be performed with higher number of patients and more controlled risk factor so it will be more accurate in determining the relationship between the duration of type 2 DM and ED.


2020 ◽  
Vol 35 (2) ◽  
pp. 130-138
Author(s):  
Fatma KH. Ali Ehmaida ◽  
Sokaina Saad Hemdan ◽  
Asmaa M. Aljebaly

This study was carried out to provide new data on patients with type 2 diabetes mellitus and any suggestions for the prevention of what is a life-threatening disorder. Four hundred and seventy-three type 2 diabetic mellitus patients from Almarj general hospital were used: (222) females and (251) males for the period from October -2017 to April – 2018.The study focused on the relationship between genders and complications of diabetes mellitus. The study showed no significant differences (P > 0.05) between hypertension, heart disease, respiratory dysfunction, nephropathy, urinary tract infection, anemia, hypothyroidism, diabetic ketoacidosis, gastric infection, and gender. On the other hand, a significant (P ≤ 0.05) relationship was found between hepatopathy and foot complications and gender. Findings showed that males with the risk of the dangers of type 2 diabetes mellitus complications were more than females in Almarj city.  


2018 ◽  
Vol 6 (1) ◽  
pp. 85
Author(s):  
Gema Akbar Wakhidana ◽  
Ancah Caesarina Novi Marchianti ◽  
Ali Santosa

Diabetes mellitus is metabolic diseases characterized by hyperglycemia caused by disturbances in insulin secretion or insulin activity. Herbal Forte Rice is rice synthetic material composed of main purple sweet potato and corn flour. It contains antioksidan, fiber, resistant starch and having moderate glycemic index. This study aimed to determine the effectivity of Herbal Forte Rice on decreasing blood glucose levels of patients type 2 DM. It used a cross-over design, the role of research subjects was both as control and treatment groups. Total sample of this research consisted of 60 samples. The treatment group was given Herbal Forte Rice for 7 days in 2 consecutive meals, while the control group did not receive any intervention. The results showed the average level of Fasting Blood Glucose (FBG) beginning and end of the treatment group 179.76 mg/dL and 138.7 mg/dL; FBG beginning and end of the control 180.87 mg/dL and 187.63 mg/dL; 2 hours post prandial Blood Glucose (2hppBG) levels of beginning and end of the treatment group 284.37 mg/dL and 183.8 mg/dL; 2hppBG levels beginning and end of the control 280.57 mg/dL and 284.13 mg/dL. This study concludes that Herbal Forte Rice effective on decreasing blood glucose levels of patients type 2 DM.   Keywords: diabetes mellitus, Rice Herbal Forte, GDP and GD2PP  


2021 ◽  
Vol 3 (2) ◽  
pp. 138-145
Author(s):  
Tri Prasetyorini ◽  
Cindy ◽  
Salbiah

Diabetes mellitus (DM) is a group of metabolic diseases with characteristics of increased blood glucose levels that occur due to abnormal insulin secretion, insulin action or both. It is necessary to monitor long-term glycemic status by measuring HbA1c levels to determine the quality of long-term blood glucose control. People with Type 2 DM are more at risk of suffering from cardiovascular disease characterized by dyslipidemia, with a characteristic description of high plasma triglyceride levels, elevated LDL levels and decreased HDL levels. The purpose of this study was to determine the relationship between HbA1c levels and levels of triglycerides, LDL and HDL. This study was an analytic observational study using a cross-sectional design. Data on each variable is secondary data obtained from patients with Type 2 DM at Jakarta Friendship Hospital for the period January-December 2018. The research sample used was 97 data of Type 2 DM patients. Chi-Square test showed an association between HbA1c levels and triglyceride levels with a value of p = 0.046 (< 0.05), there was a relationship between HbA1c levels and LDL levels with p = 0.742 (p > 0.05), and there was a relationship between HbA1c levels and HDL levels with p = 0.241 (p > 0.05). The conclusion obtained in this study is that there is a significant relationship between HbA1c levels and triglyceride levels and there was no significant relationship between HbA1c levels and LDL and HDL levels.


2020 ◽  
Vol 2 (2) ◽  
pp. 89-93
Author(s):  
Gunardi Gunardi

Diabetes mellitus type 2 (DM Type-2) is a metabolic disease which characterized by hyperglycemia due to failure of insulin secretion, insulin action or both. If DM is not handled properly, then it will arise complications in various organs of the body. The criterias of DM control including HbA1c levels and lipid fractions. Lipid pattern in patients with DM type 2 is very dependent on HbA1c control. High HbA1c is associated with high triglycerides and cholesterol. Research objective to find out the description of Hba1c, cholesterol and triglyceride levels in patients of DM type 2 at the Outpatient Poly of RSUD Tidar Magelang. Research method the research type was descriptive with observational design. Primary data were obtained from levels measurements of HbA1c, cholesterol and triglycerides.. The normal HbA1c levels 4-5,80%, good control 6,1-6,5%, moderate 6,6-7,8%, bad 8,8-14,1% respectively as much as 65,96%, 12,77%, 10,64%, and 10,90%. The normal cholesterol levels 100-160 mg/dL, moderate 200-220 mg/dL, and high 250-300 mg/dL, respectively 74,47%, 10,64%, and 14,89%. The normal triglyceride levels 70-140 mg/dL, high limit 150-165 mg/dL, and high 200-252 mg/dL respectively as much as 63,83%, 19,15% and 17,02%. Based on the age of normal HbA1c levels as much as 65,96%, normal cholesterol 74,47%, and triglycerides 63,83%. The levels of HbA1c, cholesterol, and triglycerides were mostly normal in age groups of elderly, and male. The high levels of HbA1c, cholesterol, and triglycerides were more common in elderly than in other age groups.


2021 ◽  
Vol 10 (2) ◽  
pp. 343-349
Author(s):  
Ninik Ambar Sari ◽  
Ceria Nurhayati

Background: Diabetes Mellitus (DM) is a metabolic disease characterized by high blood glucose levels as a result of insufficient insulin secretion, impaired insulin activity or both. Patients with diabetes mellitus are at risk for complications that can affect their quality of life. These complications can be minimized through self-management.  Objectives: The aim of this study was to determine the relationship between self-management and quality of life in type 2 DM patients. Design: This study was a quantitative research. The design in this study was a cross-sectional analytic with a sample of 75 people who were carried out at the endocrine polyclinic RS Pusat TNI Angkatan Laut (RSPAL) DR. Ramelan Surabaya. Research instrument used the Diabetes Self-Management Questionnaire (DSMQ) developed by Schmitt et al (2013) to determine the self-management of type 2 DM patients and to measure the quality of life using the Diabetes Quality of Life Brief (DQoL Brief) instrument developed by Burrough et al (2008). The sample siza with simple random sampling method, and data analysis using spearman rank test. Results: The results showed that there was a significant relationship between self-management and quality of life in type 2 DM patients (p-value = .000, r = .394). Conclusion: There is a significant positive relationship between the level of self-management and quality of life in type 2 DM patients. From the results of the Spearman test correlation coefficient, there is a positive sign. This means that the higher the patient's self-management, it will also improve the quality of their life. The implication of this study are nurses can increase patient knowledge by providing education that focuses on improving self-management and facilitating the provision of family support as well as supervision and monitoring related to self-management by type 2 DM patients.


Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 3211
Author(s):  
Hang-Yu Li ◽  
Dan-Dan Zhou ◽  
Ren-You Gan ◽  
Si-Yu Huang ◽  
Cai-Ning Zhao ◽  
...  

Metabolic diseases are serious threats to public health and related to gut microbiota. Probiotics, prebiotics, synbiotics, and postbiotics (PPSP) are powerful regulators of gut microbiota, thus possessing prospects for preventing metabolic diseases. Therefore, the effects and mechanisms of PPSP on metabolic diseases targeting gut microbiota are worth discussing and clarifying. Generally, PPSP benefit metabolic diseases management, especially obesity and type 2 diabetes mellitus. The underlying gut microbial-related mechanisms are mainly the modulation of gut microbiota composition, regulation of gut microbial metabolites, and improvement of intestinal barrier function. Moreover, clinical trials showed the benefits of PPSP on patients with metabolic diseases, while the clinical strategies for gestational diabetes mellitus, optimal formula of synbiotics and health benefits of postbiotics need further study. This review fully summarizes the relationship between probiotics, prebiotics, synbiotics, postbiotics, and metabolic diseases, presents promising results and the one in dispute, and especially attention is paid to illustrates potential mechanisms and clinical effects, which could contribute to the next research and development of PPSP.


2014 ◽  
Vol 14 (1) ◽  
pp. 44-50
Author(s):  
Lina María Martínez Sánchez ◽  
Gloria Inés Martínez Domínguez ◽  
María de los angeles Rodríguez Gázquez ◽  
Camilo andrés Agudelo Vélez ◽  
Juan Guillermo Jiménez Jiménez ◽  
...  

Objetivo:Explorar la relación entre la adherencia terapéutica y el control metabólicoen pacientes con Diabetes Mellitus tipo 2 (DM-2), que consultaron a una instituciónhospitalaria en Medellín-Colombia.Materiales y métodos:Estudio transversal. Lamuestra estuvo constituida por personas con 18 y más años, con diagnóstico de DM-2•PHVHVTXHILUPDURQHOFRQVHQWLPLHQWRLQIRUPDGR(OPXHVWUHRIXHQRSUREDELOtVWLFRmuestra por conveniencia. Se aplicaron las escalas Summary of Diabetes Self-CareActivities para valorar adherencia terapéutica y Duke-Unc para evaluar apoyo social.La hemoglobina glicosilada (HbA1c) fue procesada por el método inmunoturbidimé-trico de inhibición en el Equipo Cobas C-501. Se asumió como “control metabólicoadecuado” un valor de HbA1c < al 7%. Se utilizó el programa SPSS versión 19.0 parael análisis.Resultados:De los 70 pacientes estudiados: el 66% son mujeres, el 76%tiene Hipertensión arterial, el 70% tiene dislipidemias y el 16% fuma. Además, el 59%HVLQVXOLQRGHSHQGLHQWHHOWLHQH+E$F•HOQRWLHQHDSRRVRFLDO/RVfactores con mayor proporción de adherencia fueron: medicación (79%), cuidado depies (71%). Mientras que los más bajos fueron: autocontrol glicémico (32%) y ejercicio(28%). La HbA1c se correlacionó significativamente (p<0.05) con adherencia a dieta,autocontrol de glicemia, cuidado de pies, apoyo social y género.Conclusiones:Laadherencia terapéutica estuvo asociada al control metabólico en pacientes con DM-2. Objective: Explore the relationship between the therapeutic adherence and metaboliccontrol in patients with Diabetes Mellitus type 2 (DM-2), which consulted to a hospitalinstitution in Medellin-Colombia. Materials and Methods: Cross-sectional study. The


Author(s):  
Wei Zien Gan ◽  
Valsala Ramachandran ◽  
Crystale Siew Ying Lim ◽  
Rhun Yian Koh

AbstractDiabetes mellitus (DM) is a group of metabolic diseases related to the dysfunction of insulin, causing hyperglycaemia and life-threatening complications. Current early screening and diagnostic tests for DM are based on changes in glucose levels and autoantibody detection. This review evaluates recent studies on biomarker candidates in diagnosing type 1, type 2 and gestational DM based on omics classification, whilst highlighting the relationship of these biomarkers with the development of diabetes, diagnostic accuracy, challenges and future prospects. In addition, it also focuses on possible non-invasive biomarker candidates besides common blood biomarkers.


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