scholarly journals Profile of HbA1c, Cholesterol and Triglyceride in Type 2 Diabetes Mellitus

2020 ◽  
Vol 2 (2) ◽  
pp. 89-93
Author(s):  
Gunardi Gunardi
Keyword(s):  
Diabetes Mellitus ◽  
Age Groups ◽  
Good Control ◽  
The Body ◽  
Primary Data ◽  
High Hba1c ◽  
Hba1c Control ◽  
Dm Type 2 ◽  
Hba1c Levels

Diabetes mellitus type 2 (DM Type-2) is a metabolic disease which characterized by hyperglycemia due to failure of insulin secretion, insulin action or both. If DM is not handled properly, then it will arise complications in various organs of the body. The criterias of DM control including HbA1c levels and lipid fractions. Lipid pattern in patients with DM type 2 is very dependent on HbA1c control. High HbA1c is associated with high triglycerides and cholesterol. Research objective to find out the description of Hba1c, cholesterol and triglyceride levels in patients of DM type 2 at the Outpatient Poly of RSUD Tidar Magelang. Research method the research type was descriptive with observational design. Primary data were obtained from levels measurements of HbA1c, cholesterol and triglycerides.. The normal HbA1c levels 4-5,80%, good control 6,1-6,5%, moderate 6,6-7,8%, bad 8,8-14,1% respectively as much as 65,96%, 12,77%, 10,64%, and 10,90%. The normal cholesterol levels 100-160 mg/dL, moderate 200-220 mg/dL, and high 250-300 mg/dL, respectively 74,47%, 10,64%, and 14,89%. The normal triglyceride levels 70-140 mg/dL, high limit 150-165 mg/dL, and high 200-252 mg/dL respectively as much as 63,83%, 19,15% and 17,02%. Based on the age of normal HbA1c levels as much as 65,96%, normal cholesterol 74,47%, and triglycerides 63,83%. The levels of HbA1c, cholesterol, and triglycerides were mostly normal in age groups of elderly, and male. The high levels of HbA1c, cholesterol, and triglycerides were more common in elderly than in other age groups.

High HBA1C Level Is Associated With Low Heamoglobin Level

2018 ◽  
Vol 3 (02) ◽  
Author(s):  
Mafooza Rashid ◽  
B. K. Gupta, Vinay Bharat ◽  
Abhishek Gupta ◽  
Zubair Rashid
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycosylated Hemoglobin ◽  
Good Control ◽  
Diabetic Control ◽  
Medical College ◽  
High Hba1c ◽  
Normal Controls

Background: The aim of the study was to compare the hemoglobin levels among normal controls (patients) and patients of TypeII diabetes with HbA1c levels below 7 % & above 7 %.and secondly to identify the undetected cases of anemia in TypeII diabetes. Materials & Methods - 50 patients of type 2 diabetes mellitus with their glycosylated hemoglobin levels less than 7 %, 50 patients of type 2 diabetes mellitus with their glycosylated hemoglobin levels more than 7 % attending the Medicine outpatient department of Subharti Medical College and Hospital will be the subjects for the study.50 age and sex matched controls will be selected randomly from Subharti Medical College and Hospital. Informed written consent will be taken from all the subjects. The study will be conducted from January 2016 to January. Result - We studied 50 cases with HbA1C>7(poor control),50 cases with HbA1C 5.6 to7 (good control) and 50 controls with HbA1C ≤5.6, we observed in cases with HbA1C>7 (poorly control) ,the mean HbA1C is 9.9±2 and mean Hb is 9.8±1.3 as compared to cases with HbA1C 5.6 to 7(good control) where mean HbA1C is 6±0.4 and Hb is 13±0.5,this clearly indicates that in cases HbA1C is more Hb levels are low and when HbA1C is less Hb levels are higher. Conclusion - In the present study we found negative correlation between HbA1c & Hb levels. As the value of HbA1c increases, as in cases of HbA1c >7(poor diabetic control), we found low Hb levels as compared to the cases with HbA1c <7(5.6-7) (good control).

scholarly journals The effect of metformin on fasting and postprandial insulin secretion in obese patients with diabetes mellitus type 2

2007 ◽  
Vol 135 (7-8) ◽  
pp. 447-452 ◽  
Author(s):  
Mira Vukovic ◽  
Mirjana Lapcevic ◽  
Nevena Kalezic ◽  
Branislav Gvozdenovic
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Statistical Significance ◽  
The Body ◽  
Obese Patients ◽  
Peripheral Tissues ◽  
Glucose Output ◽  
Dm Type 2 ◽  
Postprandial Insulin

Introduction The main causes of reduced glucose levels during metformin therapy appear to be an increase in insulin action in peripheral tissues and reduced hepatic glucose output due to inhibition gluconeogenesis. Objective The purpose of the study was to establish the effect of metformin on fasting and postprandial insulin secretion. Method The study carried out was double blind, controlled, comparative, randomized, multicentric, including two groups of out-patient department (OPD) patients. 43 patients were administered metformin (Tefor ICN Canada), and 46 patients were given placebo. Patients enrolled in the study were newly diagnosed with diabetes mellitus (DM) type 2, glycaemia < 12 mmol/l, and had the Body Mass Index (BMI) > 30 kg/m2. Before treatment, blood biochemistry was done: fasting and postprandial glycaemia, glycosylated haemoglobin (HbA1c) value, fasting and postprandial insulinaemia, blood lipids (total cholesterol, total triglycerides, HDL cholesterol, and LDL cholesterol), and gamma glutaryl transferase (GGT) level. BMI was also established. After 42 days of treatment, fasting and postprandial insulinaemia were tested again. Analysis of the effects of therapy, and identification of co-variants for fasting and postprandial insulinaemia, were done by ANOVA two way and ANCOVA method. Results It was shown that metformin accompanied by diet, as compared to placebo accompanied by diet, lowered the fasting insulinaemia value during six weeks of therapy in obese patients with DM type 2 (24.392 mU/l vs. 25.667 mU/l), interacting both with BMI pre-therapy, and interacting with fasting insulinaemia pre-therapy (p<0.001). A significant effect of the interaction of covariants BMI and GGT was defined. As for the effect of therapy on postprandial insulinaemia, it was found that there was a high statistical significance of the effect of BMI interacting with initial values for postprandial insulinaemia before therapy, and interacting with therapy (p<0.01). Adjusted mean values for postprandial insulinaemia after therapy in the placebo group were lower as compared to the metformin group (44.807 mU/l vs. 47.114 mU/l). Conclusion It can be concluded that, as compared to placebo, metformin is more efficient in reducing insulin resistance in obese patients with DM type 2. In addition, as compared to placebo, metformin maintains more efficient productive insulin secretion, indicating that metformin protects the pancreas from beta cell depletion.

Correlation of HbA1c levels and diabetic neuropathy complications in diabetes mellitus patients

2021 ◽  
Vol 129 (s2) ◽  
pp. S293-S298
Author(s):  
Anisatul Hamida ◽  
Laily Irfana ◽  
Detty Nur Irawati
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Disease ◽  
Insulin Resistance ◽  
Diabetic Neuropathy ◽  
Pancreatic Beta Cells ◽  
The Body ◽  
Insulin Regulation ◽  
Impaired Insulin ◽  
Hba1c Levels

Introduction: Type 2 Diabetes Mellitus (DM) is a metabolic disease caused by impairments in insulin secretion by pancreatic beta cells and/or impaired insulin regulation by the body (insulin resistance). Inadequate management of DM can be a trigger of several complications, such as diabetic neuropathy.

scholarly journals The effects of education with printed material on glycemic control in patients with diabetes type 2 treated with different therapeutic regimens

2011 ◽  
Vol 68 (8) ◽  
pp. 676-683 ◽  
Author(s):  
Anujka Selea ◽  
Mirjana Sumarac-Dumanovic ◽  
Milica Pesic ◽  
Dusica Suluburic ◽  
Danica Stamenkovic-Pejkovic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Fasting Blood Glucose ◽  
Diabetes Type 2 ◽  
General Level ◽  
Treatment Team ◽  
Significant Difference ◽  
Dm Type 2 ◽  
Hba1c Levels

Background/Aim. Diabetes mellitus (DM) is considered to be an epidemic, chronic and progressive disease. The treatment of DM reqiures substantial effort from both the diabetes treatment team and a patient. Patient education is one of the treatment elements. The most efficacious form and content of education has not yet been established. However, every DM education must include introduction to a substantial number of facts about diabetes. The aim of our study was to estimate the levels of DM knowledge and glycemic control in Serbian patients with DM type 2 as well as to estimate the effects of education using printed material on the levels of glycemic control and knowledge about DM. Also, the effects of education on glycemic control and the level of knowledge in differently treated patients were estimated. Methods. The patients with DM type 2 (n = 364), aged 40 to 65 years, from three regional health centers, were randomized for the study. After informed consent, patients filled out the questionnaire, and were checked for HbA1c and fasting blood glucose. Finally, booklet ?Healthy lifestyle with diabetes mellitus type 2? was given to them. The same procedure was repeated after 3, 6 and 18 months. Results. There was a significant improvement in HbA1c levels after 3 months (8.00 ? 1.66% vs 9.06 ? 2.23%, p < 0.01) and after 6 months (7.67 ? 1.75% vs 9.06 ? 2.23%, p < 0.01). There was no further improvement in HbA1c levels after 18 months (7.88 ? 1.46% vs 7.67 ? 1.75%, p > 0.05). There was a significant improvement in the average test score (percent of correct answers per test sheet) after three monts (64.6% vs 55.6%, p < 0.01). There were no further statistically significant changes in the general level of DM knowledge after 6 months (65.0 ? 32.5% vs 64.5 ? 33.7%, p > 0.05 ) and after 18 months ( 64.8 ? 32.7 vs 64.5 ? 33.7%, p > 0.05). There was a significant difference in educational intervention response in DM type 2 patients on different therapeutic regimens. Conclusion. Education with printed material led to improvement in glycemic control and level of DM knowledge in our patients. Education with printed material may be a useful adjunct to DM treatment and should be structured according to the treatment modality.

scholarly journals Significance of HbA1c targets based on an individual approach to the treatment of patients with type 2 diabetes mellitus

2014 ◽  
Vol 17 (2) ◽  
pp. 4-9 ◽  
Author(s):  
Inna Vladimirovna Misnikova ◽  
Alexander Vasil'evich Dreval ◽  
Yulia Alexandrovna Kovaleva ◽  
Valeria Alekseevna Gubkina ◽  
Aleksey Leonidovich Odnosum
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Microvascular Complications ◽  
Age Groups ◽  
Individual Approach ◽  
The Past ◽  
Hba1c Target ◽  
Hba1c Levels

Background. Over the past few years, special attention has been paid to achieving glycaemic control for type 2 diabetes mellitus (T2DM) patients, since it is a factor for determining the risk of developing macro- and microvascular complications of diabetes. Certain modern guidelines suggest an individual approach to the choice of HbA1c target. Objective. Objective.  . of this study was to estimate the percentage of T2DM patients who have reached the HbA1c levels. This was determined based on their age and the presence of severe complications. Materials and Methods. A total of 2195 patients with T2DM were studied. The patients were divided into the following age groups:

scholarly journals MICROALBUMIN STATUS IN RELATION TO GLYCATED HAEMOGLOBIN AMONG TYPE 2 DIABETES MELLITUS IN SOUTH KERALA POPULATION-A COMPARATIVE STUDY

2020 ◽  
pp. 1-3
Author(s):  
B Shanthi
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Diseases ◽  
Age Groups ◽  
Glycated Haemoglobin ◽  
Type 2 Dm ◽  
High Hba1c ◽  
Life Threatening ◽  
Life Threatening Complication ◽  
The Relationship

Diabetes mellitus (DM) is a group of metabolic diseases which if not controlled can cause life threatening complication. The objective of the study is to assess the correlation of urine microalbumin (MAU) with (HbA1C) in type 2 DM patients. Total 180 patients diagnosed for type 2 DM, age 30-60 years were selected and fasting plasma glucose, creatinine,HbA1C and MAU were estimated.HbA1C levels and MAU levels shows significant positive correlation (r = 0.429, p<0.01) and the relationship is significant for all the three age groups. The study concluded that there was an increased prevalence of MAU and high HbA1C level among the patients with type 2 DM, and also highlights that there is a significant correlation betweenMAUlevels andHbA1Cfor allthe three agegroupswhichnecessitatesfor earlydetectionofnephropathyanduncontrolled diabetes.

scholarly journals Actual ambulatory care in patients with type 2 diabetes mellitus in Russian Federation according to open label prospectiveobservational study DIA-CONTROL

2011 ◽  
Vol 14 (4) ◽  
pp. 75-80 ◽  
Author(s):  
Marina Vladimirovna Shestakova
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Ambulatory Care ◽  
Prospective Observational Study ◽  
Open Label ◽  
Hypoglycemic Therapy ◽  
Dm Type 2 ◽  
Hba1c Levels

This review presents a comprehensive analysis of actual ambulatory care in patients with type 2 diabetes mellitus provided in 10 federal subjects withinthe period of 1 year. The analysis is based on results from non-interventional open label prospective observational study DIA-CONTROL, whichincluded 9844 patients with DM type 2. The study was aimed to assess the initial level of glycated hemoglobin and its further dynamics according tomeasurements repeated every 3 months. Composition and efficiency of hypoglycemic therapy were also estimated in these patients.Inclusion visit showed 38.5% of patients to have adequate HbA1c levels (8%, which is quite disturbing and suggests a more careful approach to instruction of healthcarespecialists.

Serum Ferritin Status of Patients with Type 2 DM Attending OPD of BIRDEM General Hospital

2020 ◽  
Vol 11 (1) ◽  
pp. 7-10
Author(s):  
Khadiza Begum ◽  
Fahmida Islam ◽  
Farjana Aktar ◽  
Murshida Aziz ◽  
Tohfa E Ayub Tahiya
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Serum Ferritin ◽  
Study Groups ◽  
Acute Phase Reactant ◽  
The Body ◽  
Iron Stores ◽  
Normal Healthy Individual ◽  
Diabetes Patients

Background: In recent times much is talked about of serum ferritin, an acute phase reactant a marker of iron stores in the body and its association with diabetes mellitus. Studies implicate that increased body iron stores and subclinical hemochromatosis has been associated with the development of glucose intolerance, type 2 diabetes and its micro as well as macrovascular complications. Material & Methods: This study was carried out to examine and to observe for any relationship between serum ferritin with Type 2 diabetes mellitus. Our study populations were included 163. Among them 81 type 2 diabetes patients as a case (M=49,F=32, mean 44.68 age in years)and 82 normal healthy individual as a control ( M=35, F=47 , mean 34.71 in years). Results: Majority were healthy outpatients who had come for regular checkup and were matched with controls. Serum ferritin and FBS were estimated and other investigations. Results showed that although Serum ferritin was in the normal range value it was increased in type 2 diabetes patients than in controls and was statistically significant, we did get a positive correlation with duration of diabetes. It can be concluded that there were positive associations between serum ferritin and FBG, age, sex among study groups. Conclusion: In conclusion our study shows that there is significant correlation between increased serum ferritin in diabetes compared to individuals with normal blood sugars in this part and hyper ferritinemia may be one of the causes for development of insulin resistance before overt diabetes. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 7-10

scholarly journals Influence of physical activity on periodontal health in patients with type 2 diabetes mellitus. A blinded, randomized, controlled trial

2021 ◽  
Author(s):  
K. Wernicke ◽  
J. Grischke ◽  
M. Stiesch ◽  
S. Zeissler ◽  
K. Krüger ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Periodontal Health ◽  
Randomized Controlled ◽  
Hba1c Levels

Abstract Objectives The aim was to investigate the effect of physical activity on periodontal health and HbA1c levels in patients with type 2 diabetes mellitus (T2DM) over a period of 6 months. Materials and methods Thirty-seven patients with non-insulin-dependent T2DM were included in the study. The intervention group (n=20) performed physical activity over a period of 6 months. The control group (n=17) did not receive any intervention. Baseline and final examinations included dental parameters and concentrations of glycosylated hemoglobin (HbA1c) and high-sensitivity C-reactive protein (hsCRP). Results Physical activity showed a positive effect on periodontal health. Both the BOP (p= 0.005) and the severity of periodontitis (p= 0.001) were significantly reduced in the intervention group compared to the control group. Furthermore, HbA1c levels were reduced (p= 0.010) significantly in the intervention group while hsCRP levels significantly increased in the control group (p= 0.04). Conclusions Within the limitations of this randomized, controlled trial, physical activity over a period of 6 months is a health-promoting measure for patients with T2DM and improves both periodontal health and HbA1c concentrations.

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