THE CHARACTERIZATION OF HEADACHE IN PATIENTS WITH DYSCIRCULATORY ENCEPHALOPATHY OF DIFFERENT GENESIS

Abstract The objective of this study was to determine the effect of two commercial mineral supplements on ewes/lamb pairs DMI and ADG. All ewes prior to lambing were maintained a sheep pellet formulated for no mineral, vitamin, or probiotic content at a rate of 2% body weight, ad libitum Bermuda hay, and ad libitum access to the control mineral supplement. Ewe/lamb pairs were randomly assigned based on twining and parity to study groups four days post-lambing. The treatment (TRT) group had 12 ewes/18 lambs, and a control (CNTRL) group had 11 ewes/17 lambs, and was conducted over 6wks. Lambs in both groups were offered ad libitum alfalfa via a creep feeding gate. The TRT group received a commercial chelated mineral mix that included Ascophyllum nodosum seaweed extract in the blend and the CNTRL received a commercial non-chelated mineral without seaweed extract. Chelated minerals were Cu, Mn, and Zn. Daily feed and ort samples were collected 2x week and dried at 55℃ for analysis. Feed was adjusted daily to maintain a 3–5% refusal rate. Samples were compiled by week and analyzed for DM, Ash, aNDF, aADF, EE, and CP. Blood samples were collected from a subset of 7 ewes per group, 3x during the study (wk1, wk3, wk6) for later trace mineral analysis (Co, Cu, Fe, Mn, Mo, Se). Results indicate a significant difference in mineral DMI between groups (P = 0.03), but no significant impact on DMI of Bermuda or alfalfa. ADG for lambs was numerically increased 0.25±0.01 TRT versus 0.23±0.01 kg CNTRL but was not statistically significant (P = 0.18). No significant differences in trace mineral levels between groups or over time was seen. All mineral levels were in the normal range for both groups. It appears the addition of the chelated mineral with Ascophyllum nodosum seaweed extract did not improve ADG or DMI, but the results of this study were potentially affected by severe weather conditions. Further study is needed under more favorable conditions to confirm product impacts in ewe/lamb pairs.

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Characterization of Fluorotic Enamel After Microabrasion and Desensitizing Agent

Odovtos - International Journal of Dental Sciences ◽

10.15517/ijds.v19i1.27998 ◽

2017 ◽

Vol 19 (1) ◽

pp. 59

Author(s):

V. Zavala-Alonso DDS, MSc,PhD ◽

G. Roque-Márquez DDS, MSc ◽

N. Patiño-Marín DDS, MSc, PhD ◽

D. Silva-Herzog DDS, MSc, PhD

Keyword(s):

Hydrochloric Acid ◽

Surface Morphology ◽

Dental Fluorosis ◽

Study Groups ◽

Superficial Layer ◽

Enamel Surface ◽

Anterior Teeth ◽

Significant Difference ◽

Desensitizing Treatment

Introduction. Enamel microabrasion is a procedure used for removing a superficial layer of enamel that has some alteration of color and/or texture caused by dental fluorosis. The purpose of this study was to compare the microhardness and micromorphology of the fluorotic enamel surface after microabrasion with 6.6% hydrochloric acid and silica or 18% hydrochloric acid and evaluate the effect of desensitizing agent exposure on the treated enamel. Materials and Methods. Twenty anterior teeth with moderate fluorosis were divided into two groups: 1) Perla-Dent® group and 2) Opalustre® group. Each buccal surface of incisors was sectioned to obtain samples 3x3 mm. The samples were then mounted in acrylic blocks. The enamel surface of the blocks was polished, after the microabrasion materials and desensitizing agent were applied according to the manufacturer's instructions. All samples were analyzed by Vickers microhardness tester and scanning electron microscopy (SEM). Results. Both experimental groups presented a decrease in the microhardness values, with statistically significant differences (p<0.0001) when comparing the baseline and after treatments values. To compare the microhardness values after both microabrasion and desensitizing treatment in the study groups, it was observed that the Perla-Dent® group obtained lower values than the Opalescence® group with a statistically significant difference (p<0.0001). The representative images of study groups in SEM showed the enamel surface morphology after Perla-Dent® treatment more irregular and a very marked relief than that observed in enamel surface morphology after Opalustre® treatment. Conclusion. The surface of the enamel was more affected with Perla-Dent® treatment than with Opalustre® treatment and the placement of UltraEz® agent does not recover its baseline microhardness.

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171 The effects of supplementing a chelated mineral containing Ascophyllum nodosum on intake and performance of creep-fed hair lambs

Journal of Animal Science ◽

10.1093/jas/skz397.184 ◽

2020 ◽

Vol 98 (Supplement_2) ◽

pp. 78-79

Author(s):

Victoria Romo ◽

Jamie A Boyd

Keyword(s):

Weather Conditions ◽

Study Groups ◽

Ascophyllum Nodosum ◽

Seaweed Extract ◽

Trace Mineral ◽

Mineral Supplement ◽

Significant Difference ◽

Ewe Lamb ◽

Ad Libitum ◽

Mineral Levels

Abstract The objective of this study was to determine the effect of two commercial mineral supplements on ewes/lamb pairs DMI and ADG. All ewes prior to lambing were maintained a sheep pellet formulated for no mineral, vitamin, or probiotic content at a rate of 2% body weight, ad libitum Bermuda hay, and ad libitum access to the control mineral supplement. Ewe/lamb pairs were randomly assigned based on twining and parity to study groups four days post-lambing. The treatment (TRT) group had 12 ewes/18 lambs, and a control (CNTRL) group had 11 ewes/17 lambs, and was conducted over 6wks. Lambs in both groups were offered ad libitum alfalfa via a creep feeding gate. The TRT group received a commercial chelated mineral mix that included Ascophyllum nodosum seaweed extract in the blend and the CNTRL received a commercial non-chelated mineral without seaweed extract. Chelated minerals were Cu, Mn, and Zn. Daily feed and ort samples were collected 2x week and dried at 55℃ for analysis. Feed was adjusted daily to maintain a 3–5% refusal rate. Samples were compiled by week and analyzed for DM, Ash, aNDF, aADF, EE, and CP. Blood samples were collected from a subset of 7 ewes per group, 3x during the study (wk1, wk3, wk6) for later trace mineral analysis (Co, Cu, Fe, Mn, Mo, Se). Results indicate a significant difference in mineral DMI between groups (P = 0.03), but no significant impact on DMI of Bermuda or alfalfa. ADG for lambs was numerically increased 0.25±0.01 TRT versus 0.23±0.01 kg CNTRL but was not statistically significant (P = 0.18). No significant differences in trace mineral levels between groups or over time were seen. All mineral levels were in the normal range for both groups. It appears the addition of the chelated mineral with Ascophyllum nodosum seaweed extract did not improve ADG or DMI, but the results of this study were potentially affected by severe weather conditions. Further study is needed under more favorable conditions to confirm product impacts in ewe/lamb pairs.

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Characterization of Fluorotic Enamel After Microabrasion and Desensitizing Agent

Odovtos - International Journal of Dental Sciences ◽

10.15517/ijds.v0i0.27998 ◽

2017 ◽

Vol 19 (1) ◽

pp. 59

Author(s):

V. Zavala-Alonso DDS, MSc,PhD ◽

G. Roque-Márquez DDS, MSc ◽

N. Patiño-Marín DDS, MSc, PhD ◽

D. Silva-Herzog DDS, MSc, PhD

Keyword(s):

Hydrochloric Acid ◽

Surface Morphology ◽

Dental Fluorosis ◽

Study Groups ◽

Superficial Layer ◽

Enamel Surface ◽

Anterior Teeth ◽

Significant Difference ◽

Desensitizing Treatment

Introduction. Enamel microabrasion is a procedure used for removing a superficial layer of enamel that has some alteration of color and/or texture caused by dental fluorosis. The purpose of this study was to compare the microhardness and micromorphology of the fluorotic enamel surface after microabrasion with 6.6% hydrochloric acid and silica or 18% hydrochloric acid and evaluate the effect of desensitizing agent exposure on the treated enamel. Materials and Methods. Twenty anterior teeth with moderate fluorosis were divided into two groups: 1) Perla-Dent® group and 2) Opalustre® group. Each buccal surface of incisors was sectioned to obtain samples 3x3 mm. The samples were then mounted in acrylic blocks. The enamel surface of the blocks was polished, after the microabrasion materials and desensitizing agent were applied according to the manufacturer's instructions. All samples were analyzed by Vickers microhardness tester and scanning electron microscopy (SEM). Results. Both experimental groups presented a decrease in the microhardness values, with statistically significant differences (p<0.0001) when comparing the baseline and after treatments values. To compare the microhardness values after both microabrasion and desensitizing treatment in the study groups, it was observed that the Perla-Dent® group obtained lower values than the Opalescence® group with a statistically significant difference (p<0.0001). The representative images of study groups in SEM showed the enamel surface morphology after Perla-Dent® treatment more irregular and a very marked relief than that observed in enamel surface morphology after Opalustre® treatment. Conclusion. The surface of the enamel was more affected with Perla-Dent® treatment than with Opalustre® treatment and the placement of UltraEz® agent does not recover its baseline microhardness.

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Model Characterization of Pulmonary Arterial Hypertension: Analysis of Lung Pathology with Respect to Human Disease

10.33015/dominican.edu/2020.bio.07 ◽

2020 ◽

Author(s):

◽

Eptisam lambu

Keyword(s):

Pulmonary Arterial Hypertension ◽

Arterial Hypertension ◽

Human Disease ◽

Vascular Remodeling ◽

Vascular Wall ◽

Lung Pathology ◽

Pulmonary Arterial ◽

Lung Pathogenesis ◽

Arterial Endothelial Cells

Pulmonary arterial hypertension (PAH) is a rare multifactorial disease characterized by abnormal high blood pressure in the pulmonary artery, or increased pulmonary vascular resistance (PVR), caused by obstruction in the small arteries of the lung. Increased PVR is also thought to be caused by abnormal vascular remodeling, due to thickening of the pulmonary vascular wall resulting from significant hypertrophy of pulmonary arterial smooth-muscle cells (PASMCs) and increased proliferation/impaired apoptosis of pulmonary arterial endothelial cells (PAECs). Herein, we investigated the mechanisms and explored molecular pathways mediating the lung pathogenesis in two PAH rat models: Monocrotaline (MCT) and Sugen5416/Hypoxia (SuHx). We analyzed these disease models to determine where the vasculature shows the most severe PAH pathology and which model best recapitulates the human disease. We investigated the role vascular remodeling, hypoxia, cell proliferation, apoptosis, DNA damage and inflammation play in the pathogenesis of PAH. Neither model recapitulated all features of the human disease, however each model presented with some of the pathology seen in PAH patients.

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Pengaruh Penggunaan Model Pembelajaran dan Konsep Diri terhadap Kemampuan Berpikir Kretif Mahasiswa

Formatif Jurnal Ilmiah Pendidikan MIPA ◽

10.30998/formatif.v3i3.129 ◽

2015 ◽

Vol 3 (3) ◽

Cited By ~ 1

Author(s):

Nurul Hikmah

Keyword(s):

Significant Interaction ◽

Creative Thinking ◽

Study Groups ◽

Learning Model ◽

Descriptive Statistics ◽

Self Concept ◽

Significant Interaction Effect ◽

Significant Difference ◽

Written Test ◽

Self Learning

<p>The purpose of this study were to determine: 1) the influence of the learning <br />model of creative thinking; 2) the influence of self-concept to think creatively, and 3) the influence of the interaction and the concept of self-learning model for creative thinking. The research method used was experimental method. A sample of 80 people selected at random from the 13 study groups. The data was collected by administering a written test questions to measure variables studied. Data analysis using descriptive statistics and 2-way ANOVA. The results showed: 1) a significant difference to the learning model with the ability to think creatively sig = 0.000; 2) there is a significant effect of self-concept of <br />the ability to think creatively with sig = 0.000, and 3) there is a significant interaction effect of learning model and self-concept of the ability to think creatively with sig = 0.018. </p>

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Caracterização da Peneira Média em Clones de Coffea canephora

REVISTA FIMCA ◽

10.37157/fimca.v5i2.58 ◽

2018 ◽

Vol 5 (2) ◽

pp. 28-31

Author(s):

Darlan Darlan Sanches Barbosa Alves ◽

Victor Mouzinho Spinelli ◽

Marcos Santana Moraes ◽

Carolina Augusto De Souza ◽

Rodrigo da Silva Ribeiro ◽

...

Keyword(s):

Genetic Improvement ◽

Block Design ◽

Coffea Canephora ◽

Coffee Production ◽

Randomized Block Design ◽

Significant Difference ◽

The Mean ◽

Four Blocks ◽

Selection Of

Introdução: O estado de Rondônia se destaca como tradicional produtor de café, sendo o segundo maior produtor brasileiro de C. canephora. No melhoramento genético de C. canephora, a seleção de plantas de elevada peneira média está associada à bebida de qualidade superior. Objetivos: O objetivo desse estudo foi avaliar a variabilidade genética de clones de C. canephora para o tamanho dos grãos, mensurado a partir da avaliação da peneira média (PM). Materiais e Métodos: Para isso, foi conduzido ao longo de dois anos agrícolas experimento no campo experimental da Embrapa no município de Ouro Preto do Oeste-RO, para a avaliação da peneira média de 130 genótipos (clones) com características das variedades botânicas Conilon, Robusta e híbridos intervarietais. O delineamento experimental utilizado foi de blocos ao acaso, com quatro repetições de quatro plantas por parcela. Resultados: Não houve resultados significativos para a interação clones X anos, indicando uma maior consistência no comportamento das plantas ao longo do tempo. Porém foram observadas diferenças significativas para o tamanho dos grãos entre os genótipos avaliados, possibilitando selecionar genótipos superiores. Conclusão: Os genótipos agruparam-se em cinco classes de acordo com o teste de média, subsidiando a caracterização de um gradiente de variabilidade da característica avaliada ABSTRACTIntroduction: Coffea canephora accounts for approximately 35% of the world's coffee production. The state of Rondônia stands out as a traditional coffee producer, being the second largest Brazilian producer of C. canephora. In the classical genetic improvement of C. anephora, the selection of plants of high average sieve is associated with a drink of superior quality. Objectives: The objective of this udy was to evaluate the genetic variability of Coffea canephora clones for the agronomic medium sieve (PM). Materials and Methods: The experiment was conducted in the experimental field of Embrapa, municipality of OuroPreto do Oeste-RO, located at coordinates 10º44'53 "S and 62º12'57". One hundred thirty genotypes (clones) of botanical characteristics Conilon, Robusta and intervarietal hybrids were evaluated in the agricultural years 2013-2014 and 2014-2015. The experimental design was a randomized block design with four blocks and four plants per plot, spacing 3.5 x 1.5 meters between plants. Results: Significant difference was found for the grain size. According to the F test, at 5% probability, the genotypes were grouped into five classes according to the mean test. Conclusion: The results obtained subsidized the characterization of a variability gradient of the evaluated trait.

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The Significance of Renal Function in Response to Cardiac Resynchronisation Therapy – The Piece of a Much Larger Puzzle

Current Vascular Pharmacology ◽

10.2174/1570161118666200414103432 ◽

2020 ◽

Vol 18 ◽

Author(s):

Agnieszka Dębska-Kozłowska ◽

Izabela Warchoł ◽

Marcin Książczyk ◽

Andrzej Lubiński

Keyword(s):

Renal Function ◽

Nyha Class ◽

Heart Association ◽

Cardiac Resynchronisation Therapy ◽

Study Groups ◽

Creatinine Concentration ◽

Significant Difference ◽

Cardiac Resynchronisation ◽

Resynchronisation Therapy

Background: Although cardiac resynchronisation therapy (CRT) is an important player in the treatment of heart failure (HF) patients, the proportion of CRT patients with no improvement in either echocardiographic or clinical parameters remains consistently high and accounts for about 30% despite meeting CRT implantation criteria. Furthermore, in patients suffering from HF, renal dysfunction accounts for as many as 30-60%. Accordingly, CRT may improve renal function inducing a systemic haemodynamic benefit leading to increased renal blood flow. Objectives: The aim of the present study was to evaluate the importance of renal function in response to resynchronisation therapy during a 12-month follow-up period. Materials and methods: The study consisted of 46 HF patients qualified for implantation of cardiac resynchronisation therapy defibrillator (CRT-D). A CRT responder is defined as a person without chronic HF exacerbations during observation whose physical efficiency has improved owing to New York Heart Association (NYHA) class improvement ≥1. Results: A statistically significant difference was noted between responders and non-responders regarding creatinine level at the 3rd month (p=0.04) and, particularly, at the 12th month (p=0.02) of follow-up (100±23 vs 139±78 μmol/l). Moreover, there was a remarkable difference between both study groups with regard to GFR CKD-EPI (glomerular filtration rate (GFR) assessed using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula) at the 6th (p=0.03) and 12th month (p=0.01) of follow-up. The reference values for initial creatinine concentrations (101 μmol/l) as well as GFR CKD-EPI (63 ml/min/1.73m2 ) were empirically evaluated to predict favourable therapeutic CRT response. Conclusions: Predictive value of GFR CKD-EPI and creatinine concentration for a positive response to CRT were found relevant.

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Success Rate of Obturation of Root Canals by Different Techniques in Primary Molars: A Comparative Clinical Study

Current Dentistry ◽

10.2174/2542579x02999200503032916 ◽

2020 ◽

Vol 2 (1) ◽

pp. 36-44

Author(s):

Satyawan G. Damle ◽

Ritika Bansal ◽

Dhanashree D. Sakhare

Keyword(s):

Success Rate ◽

Study Groups ◽

Primary Molars ◽

Control Group ◽

Second Primary ◽

Chi Square ◽

Exact Test ◽

Root Canals ◽

Significant Difference ◽

Comparative Clinical Study

Objective: To compare the success rate of different obturation procedures in primary mandibular second molars clinically and also by digital radiovisiography. Methods: A total of 40 children aged between 4-8 years with deeply carious mandibular second primary molars indicated for single session pulpectomy were selected. Canals were obturated with Metapex. The 3 study groups (Endodontic plugger, Handheld lentulospiral, Navi Tip syringe) were compared with the control group (reamer) both clinically and radiovisiographically. The data collected were statistically analyzed using Pearson’s Chi-square and Fisher’s exact test. Results: The use of Navi tip syringe led to the least number of voids followed by Endodontic plugger and Reamer and the highest number of voids was reported with Lentulospiral. Navitip presented maximum number of optimally filled cases followed by Endodontic plugger and Lentulospiral and least number of optimally filled cases with reamer. However, there was no statistically significant difference (p>0.05) in any of the groups with clinical (pain and tenderness to percussion) and radiographic parameters (presence or absence of voids and length of obturation). Conclusion: Within the limitations of the present study, though the clinical outcome was statistically insignificant, Navitip syringe exhibited encouraging results and is a promising option for obturation in primary teeth.

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Comparison of leucocyte profiles between healthy children and those with asymptomatic and symptomatic Plasmodium falciparum infections

Malaria Journal ◽

10.1186/s12936-020-03435-x ◽

2020 ◽

Vol 19 (1) ◽

Author(s):

Diana Ahu Prah ◽

Linda Eva Amoah ◽

Matthew P. Gibbins ◽

Yaw Bediako ◽

Aubrey J. Cunnington ◽

...

Keyword(s):

T Cells ◽

Plasmodium Falciparum ◽

Peripheral Blood ◽

Parasite Load ◽

Study Groups ◽

Healthy Children ◽

Peripheral Cell ◽

Peripheral Blood Leucocyte ◽

Cell Counts ◽

Significant Difference

Abstract Background The immune mechanisms that determine whether a Plasmodium falciparum infection would be symptomatic or asymptomatic are not fully understood. Several studies have been carried out to characterize the associations between disease outcomes and leucocyte numbers. However, the majority of these studies have been conducted in adults with acute uncomplicated malaria, despite children being the most vulnerable group. Methods Peripheral blood leucocyte subpopulations were characterized in children with acute uncomplicated (symptomatic; n = 25) or asymptomatic (n = 67) P. falciparum malaria, as well as malaria-free (uninfected) children (n = 16) from Obom, a sub-district of Accra, Ghana. Leucocyte subpopulations were enumerated by flow cytometry and correlated with two measures of parasite load: (a) plasma levels of P. falciparum histidine-rich protein 2 (PfHRP2) as a proxy for parasite biomass and (b) peripheral blood parasite densities determined by microscopy. Results In children with symptomatic P. falciparum infections, the proportions and absolute cell counts of total (CD3 +) T cells, CD4 + T cells, CD8 + T cells, CD19 + B cells and CD11c + dendritic cells (DCs) were significantly lower as compared to asymptomatic P. falciparum-infected and uninfected children. Notably, CD15 + neutrophil proportions and cell counts were significantly increased in symptomatic children. There was no significant difference in the proportions and absolute counts of CD14 + monocytes amongst the three study groups. As expected, measures of parasite load were significantly higher in symptomatic cases. Remarkably, PfHRP2 levels and parasite densities negatively correlated with both the proportions and absolute numbers of peripheral leucocyte subsets: CD3 + T, CD4 + T, CD8 + T, CD19 + B, CD56 + NK, γδ + T and CD11c + cells. In contrast, both PfHRP2 levels and parasite densities positively correlated with the proportions and absolute numbers of CD15 + cells. Conclusions Symptomatic P. falciparum infection is correlated with an increase in the levels of peripheral blood neutrophils, indicating a role for this cell type in disease pathogenesis. Parasite load is a key determinant of peripheral cell numbers during malaria infections.

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