EFFICIENCY OF NEW HEMOSORBENT IN ACUTE AMITRIPTYLINE AND CYCLODOL POISONING

2020 ◽  
pp. 14-18
Author(s):  
A. M. Fomin
Keyword(s):  
Clinical Effect ◽  
High Efficiency ◽  
Initial Level ◽  
Synthetic Polymer ◽  
Complex Treatment ◽  
Direct Hemoperfusion ◽  
Selective Sorption ◽  
Positive Clinical Effect ◽  
Before And After

A complex treatment of a patient with acute amitriptyline and cyclodol poisoning using enterosorption, intestinal lavage and hemosorption on a new column with a synthetic sorbent is presented. A two-layer synthetic polymer column developed for the selective sorption of cytokines by direct hemoperfusion was used for hemosorption. Quantitative determinations of amitriptyline and cyclodol levels before and after the column, as well as before and after hemosorption have showed high efficiency of the sorbent to remove the toxicant from the blood. The use of 6-hour hemosorption allowed to reduce the level of amitriptyline from the initial level by more than 4 times and the level of cyclodol - by more than 3 times to therapeutic levels and to obtain a pronounced positive clinical effect in the complex treatment of a patient with severe poisoning.

scholarly journals HEMOPERFUSION IN ACUTE PSYCHOTROPIC POISONING

ASJ. ◽  
2020 ◽  
Vol 3 (41) ◽  
pp. 36-40
Author(s):  
A. Fomin
Keyword(s):  
Clinical Effect ◽  
Synthetic Polymer ◽  
Complex Treatment ◽  
Direct Hemoperfusion ◽  
High Effectiveness ◽  
Selective Sorption ◽  
Quantitative Measurements ◽  
Positive Clinical Effect ◽  
Before And After

Presented is a complex treatment of a patient with acute amitriptyline and cyclodole poisoning using enterosorption, intestinal lavage and hemosorption on a new column with a synthetic sorbent. For hemosorption, a column with a two-layer synthetic polymer was used, developed for selective sorption of cytokines by direct hemoperfusion. Quantitative measurements of levels of amitriptyline and cyclodole before and after the column, as well as before haemosorption and after haemosorption, showed a high effectiveness of the sorbent in removing toxicant from the blood. The use of 6-hour hemosorption allowed to reduce the level of amitriptyline from the initial by more than 4 times and the level of cyclodole by more than 3 times to therapeutic levels and obtain a pronounced positive clinical effect in the complex treatment of a patient with severe poisoning.

Hydrolytic enzymes in therapy of gestosis

2021 ◽  
Vol 50 (2) ◽  
pp. 76-79
Author(s):  
K. A. Gabelova
Keyword(s):  
Blood Pressure ◽  
Immune Complexes ◽  
Clinical Effect ◽  
Hydrolytic Enzymes ◽  
Clinical Effectiveness ◽  
The State ◽  
Complex Treatment ◽  
Traditional Therapy ◽  
Positive Clinical Effect

The clinical effectiveness o f complex enzymotherapy with preparation Vobenzim in treatment o f gestosis was studied in comparison with traditional therapy. The author analyzes the course оf gestation and delivery, and the state оf neonates in women with nephropathy o f I degree, who got common treatment (28 patients) and complex treatment including Vobenzim (17patients). Positive clinical effect o f complex enzymotherapy in case o f nephropathy is displayed in decreasing of edematic syndrome, eliminating or decreasing o f proteinuria, lowering o f blood pressure and impairment o f fetalhypoxia in labors. It goes along with the reduction o f immune complexes fixed in placenta.

Ways to increase the effectiveness of treatment of psoriasis patients with dystrophic lesions of the nail plates

2021 ◽  
pp. 48-53
Author(s):  
T.О. Lytynska ◽  
L.O. Naumova
Keyword(s):  
Clinical Effect ◽  
Main Group ◽  
Degenerative Changes ◽  
Complex Treatment ◽  
Slight Improvement ◽  
Basic Therapy ◽  
Results Of Treatment ◽  
Positive Clinical Effect ◽  
Complex Therapy ◽  
Dystrophic Nail

Objective — to increase the effectiveness of treatment of psoriasis patients with degenerative changes in the nails, by including in the complex therapy of the topical drug Onychocid® Emtrix, aimed at restoring the integrity of the nail plates. Materials and methods. 38 patients with psoriasis and various forms of onychodystrophy (OD) were examined and treated. The effectiveness of therapy was evaluated based on the results of treatment of patients who were divided into two clinical groups — the main and the comparison ones. Patients in both groups received basic therapy. In addition, patients of the main group were prescribed a combined drug Onychocid® Emtrix, which was applied on the nail plates and under the tips of damaged nails once a day for 3 – 6 months. Results and discussion. Patients with psoriasis are diagnosed with dystrophic changes of nail plates of varying severity. OD of the fingers only was detected in 14 (36.8 %) patients; toes — in 5 (13.2 %); fingers and toes at the same time — in 19 (50.0 %) patients. As a result of complex treatment, in patients of the main group there was an early (already on the 2—4th week of use of the drug Onychocid® Emtrix) improvement of the appearance of deformed nails. After the course of treatment, these patients showed a positive clinical effect, i. e. decrease in thickness, normalization of density, color and structure of nail plates. At the same time, «significant improvement» and «improvement» were noted in 34 (89.5 %), «slight improvement» — in 3 (7.9 %), «no improvement» — in 1 (2.6 %) patients. Conclusions. Treatment of psoriasis patients with dystrophic nail lesions should be complex and focused, including the restoration of the integrity of the nail plates. The inclusion in the complex therapy of patients with psoriatic OD of the combined drug Onychocid® Emtrix increases the effectiveness of treatment, in particular, helps to restore the structure, shape, integrity, thickness and color of the nail plates.

scholarly journals The clinical effectiveness of impulse electrotherapy in the complex treatment of patients with chronic endometritis

2012 ◽  
Vol 93 (1) ◽  
pp. 72-76
Author(s):  
V E Radzinskiy ◽  
Yu A Petrov ◽  
M L Polina
Keyword(s):  
Short Wavelength ◽  
High Efficiency ◽  
Low Frequency ◽  
Clinical Effectiveness ◽  
High Amplitude ◽  
Complex Treatment ◽  
Chronic Endometritis ◽  
Electrical Signals ◽  
Before And After ◽  
Adaptive Reactions

Aim. To evaluate the clinical effectiveness of impulse electrotherapy in the complex treatment of patients with different variants of chronic endometritis based on the evaluation of adaptive reactions and immune status. Methods. Conducted was a clinical and laboratory examination of 550 women with early reproductive losses, who were divided into three groups. Studied was the efficacy of electro-impulse therapy with high-amplitude short-wavelength low-frequency electrical signals using the apparatus «SKENAR» (SKENAR-therapy) in the complex treatment of 269 women with chronic endometritis (first group). The second group included 67 women with similar variants of chronic endometritis, who were treated without the physiotherapy component. 54 patients refused the proposed rehabilitation activities (third group). Results. New data has been obtained on the adaptive reactions of the female body before and after treatment during different types of chronic endometritis. The frequency of disadaptation was highest during the hypoplastic form of chronic endometritis. Shown was the high efficiency of electro-impulse therapy, using the apparatus «SKENAR» in the complex treatment of chronic endometritis due to the normalization of parameters of immunoreactivity. It was established that SKENAR-therapy of chronic endometritis promotes early normalization of adaptive reactions in comparison to conventional methods of treatment. Conclusion. Rehabilitation treatment of chronic endometritis in combination with electro-impulse therapy with high-amplitude short-wavelength low-frequency electrical signals contributes to the recovery of immunoreactivity and to the formation of favorable adaptation reactions.

scholarly journals Advanced treatment of effluent extended aeration process using biological aerated filter (BAF) with natural media: modification in media, design and backwashing process

AMB Express ◽  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mohammad Malakootian ◽  
Ali Toolabi ◽  
Saeed Hosseini
Keyword(s):  
High Efficiency ◽  
Treatment Plant ◽  
Hospital Wastewater ◽  
Optimal Method ◽  
Metal Grid ◽  
Before And After ◽  
The Media ◽  
Aeration Process ◽  
Aerated Filter ◽  
Natural Media

AbstractBiological aerated filters (BAFs) have high filtration efficiency due to their tolerance of hydraulic and organic shocks are suitable for the treatment of complex and sanitary wastewater. In this study, for the first time, natural media of date kernel from Bam city was used as the BAF reactor media, with a meshing sand filter separated by a standard metal grid from the natural filter section used at the end of the reactor. This can be considered an innovation in the media and filtration. Aeration in the related reactor with 160 cm height was performed bilaterally as up-flow and continuously by nozzles throughout the reactor media. In this work, the actual effluent of the hospital wastewater treatment plant was employed as the inflow wastewater to the reactor, and its organic and inorganic parameters were measured before and after the treatment by the BAF reactor. The backwashing process was also studied in three ways: bottom backwashing (TB), top backwashing (BB), and top and bottom backwashing (TBBS), to determine the amount of water consumed and to achieve the desired result. According to the results obtained in this study, the removal efficiencies of inorganic and microbial contaminants, amoxicillin and azithromycin were obtained as follows: BOD5: 98.48%, COD: 92.42%, $${\text{NO}}_{3}^{ - }$$ NO 3 - : 99.4%, P: 93.3%, Coliforms: 97%, Color: 42.8%, Turbidity: 95%, Sulphate: 30%, TSS: 98.9%, Amoxicillin: 20% and azithromycin: 13%. In the backwashing process, the amount of water consumed in these three TB, BB, and TBBS methods were obtained 300, 164, and 118 L, respectively, So, TBBS method was selected as the optimal method. Based on the results obtained in this study, it is concluded that the BAF process with natural date kernel has a high efficiency in removing organic and inorganic contaminants from hospital wastewater, also the concentration of most of the effluent parameters was less or in accordance with EPA standard.

The effect of hirudotherapy on cerebral circulatory homeostasis in patients with genital endometriosis

2020 ◽  
pp. 58-66
Author(s):  
Ya. I. Uraeva ◽  
I. I. Ivanova ◽  
N. N. Lazarenko ◽  
E. V. Filatova ◽  
I. A. Pankova ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Drug Therapy ◽  
Cerebral Circulation ◽  
The State ◽  
Control Group ◽  
Complex Treatment ◽  
Statistical Regression ◽  
Treatment Results ◽  
Standard Drug ◽  
Before And After

The results of the treatment of women (n = 94) suffering from genital endometriosis are presented. The first (control, n = 30) group of women received standard drug therapy; the second (main, n = 64) group of women additionally had hirudotherapy procedures using medical leeches. The course of treatment consisted of 10–12 procedures. The state of cerebral circulation was assessed according to the rheoencephalography data before and after the treatment, as well as after 1, 3, 6, and 9 months. As a result, in patients in the 2-nd (main) group receiving complex treatment, the state of cerebral circulation improved signifi cantly. Moreover, according to the statistical regression analysis, it was possible to predict its further decrease by two periods ahead, compared with the treatment results in patients in the 1-st (control) group.

scholarly journals EFFICACY AND SAFETY OF NASAL SPRAY PREVALIN IN THE TREATMENT OF ALLERGIC RHINITIS PATIENTS

2012 ◽  
Vol 9 (5) ◽  
pp. 55-59
Author(s):  
A A Tsyvkina ◽  
L V Luss ◽  
S V Tsarev ◽  
N V Shartanova
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Cavity ◽  
Nasal Spray ◽  
Clinical Effect ◽  
Clinical Symptoms ◽  
Efficacy And Safety ◽  
Nasal Breathing ◽  
Results Of Treatment ◽  
Functional Methods ◽  
Positive Clinical Effect

Background. To study of efficacy, tolerability and safety of nasal spray Prevalin in the treatment of allergic rhinitis patients. Methods. 30 patients with allergic rhinitis in the age of18 till 45 years were observed. Prevalin was given as one insufflation into each nasal cavity 3 times a day for 21 days. Results of treatment were assessed by the dynamics of clinical symptoms and the results of functional methods . Results. The positive clinical effect was observed in 22 patients (73,3%), using Prevalin. Clinical effect was characterized by the restoration of nasal breathing, reduce swelling of the nasal mucosa. We did not establish a good result of treatment in 8 patients. Conclusion. The study demonstrated clinical efficacy and safety of spray Prevalin.

scholarly journals Efficiency Of Intra-Articular Administration In Early Osteoarthrosis

2020 ◽  
Vol 02 (11) ◽  
pp. 22-27
Author(s):  
Islamova K. A . ◽  
◽  
Khasanov F. Sh ◽  
Toirov E. S. ◽  
◽  
...  
Keyword(s):  
Visual Analogue Scale ◽  
Knee Joint ◽  
Treatment Outcomes ◽  
Analogue Scale ◽  
Clinical Effect ◽  
Early Stage ◽  
Knee Joints ◽  
Joint Function ◽  
Early Osteoarthritis ◽  
Positive Clinical Effect

The purpose of this study was to investigate the function of knee joints in patients with early osteoarthritis (OA, according to the criteria of the American rheumatology Association 2010) stage I-III using visual analogue scale (VAS) for pain intensity and treatment outcomes, Lequesne index, expert indicators, samples of 4 meter walk to assess the effectiveness of intra-articular injection Hyaluronic Chondro. 80 patients aged 28 to 55 years were examined. The treatment regimen included recommendations from the European rheumatology League (EULAR, 2016) and Russia (Nasonov E. L., 2017). The results of therapy were evaluated in two groups. The first group included 43 patients who received Hyaluronic Chondro in the form of intra-articular injections, the second-37 patients who received chondroprotectors inside or in the form of intramuscular injections. Conclusion. Intra-articular administration of the drug Chondrogard has a positive clinical effect in early stage II-III OA with moderate impairment of knee joint function. The course of treatment should last at least 2 months

scholarly journals Research of the Clinical Effect of Kyphoplasty in the Treatment of Multiple Senile Osteoporotic Spinal Fractures

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Tianhui Liu ◽  
Jianmin Cui
Keyword(s):  
Clinical Effect ◽  
Spinal Fractures ◽  
The Elderly ◽  
Effective Rate ◽  
Clinical Indicators ◽  
Medical Institutions ◽  
Osteoporotic Vertebral Fractures ◽  
Study Evaluation ◽  
Before And After ◽  
Osteoporotic Spinal Fractures

Objective: To evaluate the clinical effect of kyphoplasty in the treatment of multiple osteoporotic vertebral fractures in the elderly. Methods: The duration of the study was selected from January 2018 to December 2020, and 38 patients with multiple osteoporotic spinal fractures were selected for study evaluation. All patients were treated with kyphoplasty. The clinical indicators of the two groups were compared and analyzed. Results: The total effective rate was 94.7% and the complication rate was 5.3%. The height of midline, anterior and posterior vertebral body, Cobb angle, VAS score, ODI score and ADL score of 38 patients before and after treatment were compared, which were significantly better than those before treatment (P<0.05). Conclusion: The clinical effect of kyphoplasty in the treatment of elderly patients with multiple osteoporosis is significant, which can be promoted in all levels of medical institutions.

scholarly journals Effect of iRoot BP Plus Pulpotomy for Immediate Repair in Children with Young Permanent Teeth Crown Fracture

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Jiaying Song
Keyword(s):  
Success Rate ◽  
Clinical Effect ◽  
Permanent Teeth ◽  
Control Group ◽  
Observation Group ◽  
Control Groups ◽  
Before And After ◽  
Random Number Table ◽  
The Difference ◽  
And Control

Objective: To explore the clinical effect of iRoot BP Plus pulpotomy for immediate repair in children with young permanent teeth crown fracture. Methods: From September 2017 to October 2018, 80 children (80 affected teeth) with young permanent teeth crown fracture who treated in the hospital were selected as the research objects. Random number table method was used to divide them into observation and control groups with each group of forty patients (40 affected teeth). The children in the control group were treated with calcium hydroxide resin, while the observation group were treated with iRoot BP Plus for immediate repair. The surgical success rate was compared between the two groups, and the pulp vitality before and after treatment were compared. Results: At 3 months and 6 months after surgery, the success rate of children in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). The percentage of children with negative pulp activity in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Immediate repair with iRoot BP Plus pulpotomy in children with young permanent teeth crown fracture has significant clinical effect.

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