Age Influence in the Prognosis of Bacterial Secondary Peritonitis

2017 ◽  
Vol 68 (5) ◽  
pp. 1023-1027
Author(s):  
Dorel Firescu ◽  
Cristina Serban ◽  
Aurel Nechita ◽  
Mihaela Dumitru ◽  
Laura Rebegea
Keyword(s):  
Retrospective Study ◽  
Aging Process ◽  
The Body ◽  
Secondary Peritonitis ◽  
Metabolic Alterations ◽  
Clinical Hospital ◽  
Bacterial Peritonitis ◽  
Severe Peritonitis ◽  
The Impact

Today the age of 60-65 years old is considered the seniority threshold. The structural, functional and metabolic alterations which occur following to the aging process determine an exacerbation of the impact which any aggression will have on the body. This retrospective study analyses a group of 245 patients with severe peritonitis, which had been hospitalized and treated in Surgery 2nd Clinic of the Sf. Apostol Andrei Emergency Clinical Hospital in the period 2007-2016. The median age 54 years old [range 30-95]; 68 patients (27.76% of cases) were ] 65 years old (65+) and 177 patients (72.24% of cases) with age between [ 65 years old (65-). Out of the results obtained, it is obvious the impact of age in the evolution and prognosis of bacterial peritonitis.

Trace Elements Burden in Geriatric Hemodialysis Patients: A Prospective Multicenter Collaborative Study

1997 ◽  
Vol 20 (10) ◽  
pp. 553-556 ◽  
Author(s):  
K.Y. Hung ◽  
C.Y. Ho ◽  
Y.M. Kuo ◽  
S.H. Lee ◽  
S.J. Hseih ◽  
...  
Keyword(s):  
Aging Process ◽  
Collaborative Study ◽  
Atomic Absorption Spectrophotometry ◽  
The Body ◽  
Blood Levels ◽  
Blood Concentrations ◽  
Normal Limits ◽  
Starting Point ◽  
Cellulose Membranes ◽  
The Impact

Introduction Hemodialysis therapy and the aging process bave been reported to interfere with the trace element (TE) status in the body. This multicenter collaborative study on blood levels of TE in geriatric hemodialysis (HD) patients was carried out with an aim to clarify the impact of the aging process and HD therapy on the TE status in such patients. Methods One hundred and fifty-one HD patients (65 male, 86 female), all aged over 60 (68.2±3.86 y), and 112 elderly controls (58 male, 54 female) with a mean age of 67.5±3.03 were enrolled. All patients underwent standard HD for at least 6 months. The artificial kidneys used were hollow-fiber dialyzers of cellulose membranes. Water used for HD was prepared by reverse osmosis. Blood was collected in the morning prior to dialysis and after fasting. Atomic absorption spectrophotometry was applied to measure blood levels of Pb, Cd and Hg as well as plasma levels of Cu, Zn and Al. Data are presented as mean ± SEM. Student's t-test and linear regression were applied for statistics. Results Our geriatric chronic HD patients showed a marked elevation of blood Al and decreased plasma Zn concentrations. The blood levels of Cu, Cd, Pb and Hg were within normal limits. The blood concentrations of Al, Cu and Pb were significantly higher in HD patients than in the normal elderly controls, whereas Cd and Hg were similar in both groups, and Zn were lower in HD patients. Plasma Zn value decreased as dialysis duration increased, however there was a reversely linear correlation between plasma Zn and age. Conclusions This data reported can be regarded as a starting point and may serve as an insight to further studies on TE imbalances in geriatric and chronic HD populations.

scholarly journals RISK FACTORS OF PRE-CANCER CERVICAL DISEASES IN WOMEN OF REPRODUCTIVE AGE

2020 ◽  
Vol 16 (1) ◽  
pp. 17-21
Author(s):  
O.A. Dyndar ◽  
T.R. Nykoniuk ◽  
O.S. Neimark ◽  
V.A. Polovynka ◽  
S.L. Neimark
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Statistical Analysis ◽  
Trichomonas Vaginalis ◽  
Negative Impact ◽  
The Body ◽  
Reproductive Age ◽  
Sexual Life ◽  
Women Of Reproductive Age ◽  
The Impact

Relevance. Today, the nature of the impact of the inflammatory process caused by Trichomonas infection on the persistence of HPV and immune response, as a consequence of the progression of intraepithelial lesions of the cervix, is not fully understood. Objectives: based on a retrospective clinical and statistical analysis to determine the risk factors for cervical dysplasia in women of reproductive age. Materials and methods. A clinical and statistical analysis for 392 medical records of patients of reproductive age with verified HPV and Trichomonas Vaginalis, who received pathogenetic therapy at the clinical bases of the Bogomolets National Medical University Obstetrics and Gynecology № 3 Department and LLC "Clinic Profimed" for 2015-2019. As a result of a retrospective study of patients systematized by age, complaints, the presence of genital and extragenital pathology, reproductive history and the state of reproductive function, social status. Results. According to the analysis of anamnesis indicators, the main risk factors for precancerous cervical conditions were: early onset of sexual life, menstrual disorders (29.1%), high incidence of childhood infectious diseases (63.5%), somatic pathology (71.2 %), irregular use of barrier contraception (19.9%), genital diseased caused by sexually transmitted infections (STD), including HPV and Trichomonas Vaginalis, frequent abortions (41.6%) and childbirth with cervical trauma, low level of medical and sexual cultures and smoking (65.3%). The systemic negative impact of numerous risk factors on the body contributed to cervical intraepithelial neoplasia (CIN) development in women of reproductive age. Conclusion. The retrospective study proves the need for stratification of patients with for CIN risk, requires management of cervical pathology in women with HPV and detected Trichomonas Vaginalis, which will increase the effectiveness of diagnosis, treatment and recurrence  prevention.

scholarly journals Impact of Estrogen Withdrawal and Replacement in Female Mice along the Intestinal Tract. Comparison of E2 Replacement with the Effect of a Mixture of Low Dose Pollutants

2021 ◽  
Vol 18 (16) ◽  
pp. 8685
Author(s):  
Claudie Pinteur ◽  
Benoit Julien ◽  
Nathalie Véga ◽  
Hubert Vidal ◽  
Danielle Naville ◽  
...  
Keyword(s):  
Low Dose ◽  
The Body ◽  
Estrogen Regulation ◽  
Metabolic Alterations ◽  
Gut Homeostasis ◽  
Genes Encoding ◽  
Estrogen Withdrawal ◽  
High Sucrose Diet ◽  
The Impact ◽  
High Sucrose

Postmenopausal women represent a vulnerable population towards endocrine disruptors due to hormonal deficit. We previously demonstrated that chronic exposure of ovariectomized C57Bl6/J mice fed a high-fat, high-sucrose diet to a low-dose mixture of chemicals with one dioxin, one polychlorobiphenyl, one phthalate, and bisphenol A triggered metabolic alterations in the liver but the intestine was not explored. Yet, the gastrointestinal tract is the main route by which pollutants enter the body. In the present study, we investigated the metabolic consequences of ovarian withdrawal and E2 replacement on the various gut segments along with investigating the impact of the mixture of pollutants. We showed that genes encoding estrogen receptors (Esr1, Gper1 not Esr2), xenobiotic processing genes (e.g., Cyp3a11, Cyp2b10), and genes related to gut homeostasis in the jejunum (e.g., Cd36, Got2, Mmp7) and to bile acid biosynthesis in the gut (e.g., Fgf15, Slc10a2) and liver (e.g., Abcb11, Slc10a1) were under estrogen regulation. Exposure to pollutants mimicked some of the effects of E2 replacement, particularly in the ileum (e.g., Esr1, Nr1c1) suggesting that the mixture had estrogen-mimetic activities. The present findings have important implications for the understanding of estrogen-dependent metabolic alterations with regards to situations of loss of estrogens as observed after menopause.

Physical activity and the aging process

2021 ◽  
Vol 10 (2) ◽  
pp. 59-64
Author(s):  
Joanna Leśniewicz ◽  
◽  
Marcin Ferdynus ◽  
Danuta Wojterzak ◽  
Łukasz Banasiak ◽  
...  
Keyword(s):  
Physical Activity ◽  
Old Age ◽  
Social Life ◽  
Aging Process ◽  
Well Being ◽  
The Elderly ◽  
The Body ◽  
The Impact ◽  
Positive Effect

After reaching old age, the elderly most often withdraw from social life. This is a serious problem because by isolating themselves from society they become less active. This has an impact on the emergence of many diseases related to both old age and the impact of physical inactivity on the body. The aim of the study was to present the consequences of the aging process in various aspects of the body’s functioning and the role of physical activity in eliminating these consequences. Unfortunately, there are still too few activities focused on physical activity for people over 65. This should change, because physical activity has a very positive effect on the human body and its well-being. Additionally, it can be observed that the earlier physical activity is started, the less changes in the body associated with the progressive aging process will occur. Such a person will be more agile and will not have major problems in dealing with overcoming the difficulties of everyday life.

The Impact of Shariah Governance and Corporate Governance on the Risk Management Practices: Evidence from Local and Foreign Islamic Banks in Malaysia

2018 ◽  
Vol 15 (2) ◽  
pp. 1-20
Author(s):  
Sabri Embi ◽  
Zurina Shafii
Keyword(s):  
Risk Management ◽  
Corporate Governance ◽  
Management Practices ◽  
Principal Component ◽  
T Test ◽  
The Body ◽  
Primary Data ◽  
Islamic Banks ◽  
Shariah Governance ◽  
The Impact

The purpose of this study is to examine the impact of Shariah governance and corporate governance (CG) on the risk management practices (RMPs) of local Islamic banks and foreign Islamic banks operating in Malaysia. The Shariah governance comprises the Shariah review (SR) and Shariah audit (SA) variables. The study also evaluates the level of RMPs, CG, SR, and SA between these two type of banks. With the aid of SPSS version 20, the items for RMPs, CG, SR, and SA were subjected to principal component analysis (PCA). From the PCA, one component or factor was extracted each for the CG, SR, and RMPs while another two factors were extracted for the SA. Primary data was collected using a self-administered survey questionnaire. The questionnaire covers four aspects ; CG, SR, SA, and RMPs. The data received from the 300 usable questionnaires were subjected to correlation and regression analyses as well as an independent t-test. The result of correlation analysis shows that all the four variables have large positive correlations with each other indicating a strong and significant relationship between them. From the regression analysis undertaken, CG, SR, and SA together explained 52.3 percent of the RMPs and CG emerged as the most influential variable that impacts the RMPs. The independent t-test carried out shows that there were significant differences in the CG and SA between the local and foreign Islamic banks. However, there were no significant differences between the two types of the bank in relation to SR and RMPs. The study has contributed to the body of knowledge and is beneficial to academicians, industry players, regulators, and other stakeholders.

Influence of DAFS-25+polizon composition on blood and functional state of liver of steers at fattening

2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  
Keyword(s):  
Functional State ◽  
White Blood Cells ◽  
Live Weight ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Standard Diet ◽  
The Impact ◽  
Experimental Group ◽  
Stimulation Of

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.

Breech Presentation: Vaginal Delivery or Caesarean Section?

2016 ◽  
Vol 2 (1) ◽  
pp. 153
Author(s):  
Tomescu Cezar Laurentiu ◽  
Rodica Sîrbu ◽  
Emin Cadar ◽  
Brezeanu Dragos ◽  
Aneta Tomescu
Keyword(s):  
Retrospective Study ◽  
Caesarean Section ◽  
Vaginal Delivery ◽  
Total Population ◽  
Population Sample ◽  
Breech Presentation ◽  
Current Paper ◽  
Clinical Hospital ◽  
Obstetrics And Gynaecology ◽  
Number Of Patients

The incidence of breech presentation is approximately 3,97%. Breech presentation is considered as being “borderline eutocic” and it requires carefully monitoring both the foetus and the mother. The aim of the current paper is to evaluate the preffered method of delivery in case of breech presentation. The paper presents a retrospective study performed in the Obstetrics and Gynaecology Departments of the County Emergency Clinical Hospital “Sf. Apostol Andrei” in Constanta, during a period of 5 years (2010-2014). The methods of birth were analyzed for a lot of 1104 patients with breech presentation with ages ranging between 16 and 44 years old. The total number of patients who gave birth through vaginal delivery was of 139 patients, amounting to 12.59% of the total population sample. The number of patients that gave birth through C-section was 965, which amounts to 87.4% of the total population sample. Birth through C-section is preferred by both obstetricians and patients alike, due to the fact that vaginal delivery is associated with a higher foetal risk in breech presentation.

Comparative assessment of morphological mechanisms of maintaining structural liver homeostasis in the dynamics of exposure to coal-rock dust and sodium fluoride on the body

2020 ◽  
pp. 189-194
Author(s):  
M. S. Bugaeva ◽  
O. I. Bondarev ◽  
N. N. Mikhailova ◽  
L. G. Gorokhova
Keyword(s):  
Sodium Fluoride ◽  
Morphological Changes ◽  
The Body ◽  
System Level ◽  
Production Factor ◽  
Coal Rock ◽  
The Impact ◽  
Structural Homeostasis ◽  
Rock Dust

Introduction. The impact on the body of such factors of the production environment as coal-rock dust and fluorine compounds leads to certain shift s in strict indicators of homeostasis at the system level. Maintaining the relative constancy of the internal environment of the body is provided by the functional consistency of all organs and systems, the leading of which is the liver. Organ repair plays a crucial role in restoring the structure of genetic material and maintaining normal cell viability. When this mechanism is damaged, the compensatory capabilities of the organ are disrupted, homeostasis is disrupted at the cellular and organizational levels, and the development of the main pathological processes is noted.The aim of the study is to compare the morphological mechanisms of maintaining structural homeostasis of the liver in the dynamics of the impact on the body of coal-rock dust and sodium fluoride.Materials and methods. Experimental studies were conducted on adult white male laboratory rats. Features of morphological mechanisms for maintaining structural homeostasis of the liver in the dynamics of exposure to coal-rock dust and sodium fluoride were studied on experimental models of pneumoconiosis and fluoride intoxication. For histological examination in experimental animals, liver sampling was performed after 1, 3, 6, 9, 12 weeks of the experiment.Results. The specificity of morphological changes in the liver depending on the harmful production factor was revealed. It is shown that chronic exposure to coal-rock dust and sodium fluoride is characterized by the development of similar morphological changes in the liver and its vessels from the predominance of the initial compensatory-adaptive to pronounced violations of the stromal and parenchymal components. Long-term inhalation of coal-rock dust at 1–3 weeks of seeding triggers adaptive mechanisms in the liver in the form of increased functional activity of cells, formation of double-core hepatocytes, activation of immunocompetent cells and endotheliocytes, ensuring the preservation of the parenchyma and the general morphostructure of the organ until the 12th week of the experiment. Exposure to sodium fluoride leads to early disruption of liver compensatory mechanisms and the development of dystrophic changes in the parenchyma with the formation of necrosis foci as early as the 6th week of the experiment.Conclusions. The study of mechanisms for compensating the liver structure in conditions of long-term exposure to coal-rock dust and sodium fluoride, as well as processes that indicate their failure, and the timing of their occurrence, is of theoretical and practical importance for developing recommendations for the timely prevention and correction of pathological conditions developing in employees of the aluminum and coal industry.The authors declare no conflict of interests.

Experience in the use of double broncholytic therapy in occupational practice

2019 ◽  
pp. 303-307
Author(s):  
Elena A. Beigel ◽  
Natalya G. Kuptsova ◽  
Elena V. Katamanova ◽  
Oksana V. Ushakova ◽  
Oleg L. Lakhman
Keyword(s):  
Quality Of Life ◽  
Personal Data ◽  
The Body ◽  
Step Test ◽  
Aluminum Production ◽  
Chronic Obstructive ◽  
Body Plethysmography ◽  
Occupational Copd ◽  
The Impact

Introduction. Occupational chronic obstructive pulmonary disease (COPD) is one of the leading nosological forms of occupational respiratory disease. Numerous studies have shown high effectiveness of the combination of indacaterol/glycopyrronium (Ultibro®breezhaler®) on the impact on clinical and functional indicators in the treatment of COPD in General practice.The aim of the investigation the case of occupational COPD with the analysis of the dynamics of functional indicators, tolerance to physical load and evaluation of the quality of life of workers engaged in aluminum production by using combination of indacaterol/glycopyrronium.Materials and methods. The random sampling method included 20 men, workers of aluminum production, with the established diagnosis of professional COPD at the age of 40 to 60 years. The survey was conducted (Borg scale, medical Research Council scale (mMRC) and COPD Assessment Test (CAT). Functional methods of studies were conducted: spirometry, body plethysmography, electrocardiography (ECG) and the six-minute stepper test (6-MST).Results. Against the background of 8 weeks of therapy, the volume of forced exhalation for 1 minute (FEV1) increased by 14.7% and amounted to 67.90% of the due values, the forced vital capacity of the lungs (FVC) increased by 11.3% and amounted to 76.95% of the due. According to the body plethysmography (BPG) is set to decrease in residual lung volume on average by 13.4% and static hyperinflation, confirmed by the decrease in functional residual volume (FRV) of 18.8%. During the study period increased physical activity of patients. The average difference between the distance traveled in the six-minute step test before and after treatment was 58.8 m. The analysis of personal data showed that the quality of life of patients improved, the total score in the questionnaire CAT at the beginning of the study was 16.9 points, and after 8 weeks decreased by 63% and amounted to 10.7 points.Conclusions: The Results indicate a positive effect of combination therapy with indacaterol/glycopyrronium on the course and progression of occupational COPD.

Studying Abroad in Nepal: Assessing Impact

2003 ◽  
Vol 9 (1) ◽  
pp. 175-188 ◽  
Author(s):  
Patricia Farrell ◽  
Murari Suvedi
Keyword(s):  
Personal Development ◽  
Intellectual Development ◽  
Longitudinal Research ◽  
Adult Learning Theory ◽  
Academic Program ◽  
The Body ◽  
Study Abroad Programs ◽  
Studying Abroad ◽  
Perceived Impact ◽  
The Impact

The purpose of this study is to analyze the reported or perceived impact of studying in Nepal on student’s academic program, personal development and intellectual development. The study draws upon adult learning theory to analyze survey instrument data, interviews, and case studies to discern the impact of the program on college students and to contribute to the body of longitudinal research on U.S. study abroad programs.

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