Influence of DAFS-25+polizon composition on blood and functional state of liver of steers at fattening

2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  
Keyword(s):  
Functional State ◽  
White Blood Cells ◽  
Live Weight ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Standard Diet ◽  
The Impact ◽  
Experimental Group ◽  
Stimulation Of

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.

The drug Argovit for treatment of piglets when intestinal infections

2021 ◽  
pp. 22-30
Author(s):  
V. I. Raitskaya
Keyword(s):  
Live Weight ◽  
Gastrointestinal Diseases ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Basic Drug ◽  
Treatment And Prevention ◽  
Intestinal Infections ◽  
Inflammatory Processes ◽  
Experimental Group

The drug Argovit developed in the LLC Vector-Vita Research and Production Center has antimicrobial and astringent properties, easily fits into the technology of housing farm animals and poultry in cases of uncomplicated colibacteriosis and is effective in isolated use, it is cheaper than other drugs, which makes it attractive in the modern market of biological products. The purpose of the research was to study the effectiveness of the drug Argovit for the treatment and prevention of gastrointestinal diseases of piglets in comparison with the basic drug Baitril used in the farm. Piglets of the experimental group (n=20) with the syndrome of gastrointestinal diseases have been treated with 1,0 % aqueous solution of the drug Argovit at a dose of 2 ml/kg of live weight 2 times a day until clinical recovery. The drug contributed to a lighter course and reduced the duration of the disease by half, while the livability of piglets reached 90,0 %. There was also a weakening of inflammatory processes in the body of piglets of both groups, which was characterized by the decrease in the level of leukocytes in piglets of the experimental group during treatment from 12,9±0,75 to 10,1±0,89×10⁹/l, and in the control group from 11,3±1,20 to 9,0±0,04×10⁹/l. The platelet content in animals at the beginning of the experiment was slightly higher than the lower limit of the norm in the experimental group by 1,8 %, in the control group by 4,7 %. At the same time, the restoration of homeostasis and the decrease in the level of protein in the blood serum have been observed. It has been found that the use of the drug Argovit to piglets during the suckling period and after weaning improves the morphological and biochemical parameters of blood due to the protective forces of protein by 4,7 %, reduces the phenomena of diarrhea, and as a result increases their livability.

scholarly journals Effectiveness of Bacillus subtilis (Vitafort) probiotic used for raising broiler chickens

2022 ◽  
Vol 78 (02) ◽  
pp. 6621-2022
Author(s):  
RIFKAT FAIRUSHIN ◽  
SVETLANA SHAKIROVA ◽  
RIMMA GANIEVA ◽  
GALIYA SHAKIROVA
Keyword(s):  
Bacillus Subtilis ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Broiler Chickens ◽  
White Blood Cells ◽  
Live Weight ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Daily Growth

Unbalanced nutrition as well as diseases of infectious and non-infectious etiology lead to a decrease in production and a significant loss of farm animals and birds. To mitigate these problems, various probiotic drugs (probiotics) are introduced into the diets of birds and animals for preventive purposes. The aim of the research was to study the effect of the Vitafort probiotic, containing antagonistic bacteria of the endophytic strain Bacillus subtilis B11, on the body of broiler chickens. The effect of Vitafort was assessed by measuring the live weight and average daily growth of birds. In addition, a morphological study of blood was carried out and the content of Bacillus subtilis in the small intestine was determined. It was found that the endophytic strain Bacillus subtilis B11 improved the intestinal microflora. Thus, on day 5 of its use, the number of microorganisms varied from 4.1 × 104 to 8.2 × 104 CFU/g, and on day 42 the same number varied from 4 × 108 to 5.8 × 108 CFU/g on day 42, the contents of red blood cells, haemoglobin, and white blood cells in the blood of chickens from the experimental group were higher by 6.44%, 3.44%, and 2.11%, respectively, than they were in the control group. Considering the above facts, it can be assumed that the absorption of nutrients in the intestine improved, and metabolic processes were activated due to an increase in the transport abilities of red blood cells.

STUDY OF RESISTANCE OF THE PIG BODY WHEN USING A COMPLEX MICROFEED PRODUCT IN NUTRITION

2021 ◽  
Vol 1 (1) ◽  
pp. 86-90
Author(s):  
L.A. Nikanova ◽  
Keyword(s):  
Green Algae ◽  
Blood Cells ◽  
White Blood Cells ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Blue Green Algae ◽  
Organic Iodine ◽  
Experimental Group

The object of research is the components of feed additives, namely dihydroquercetin, blue-green algae spirulina and organic iodine, in various combinations used in feeding piglets from the first days of feeding and before transferring them to fattening, at the age of 90 days. Three groups of piglets, one control and two experimental ones, were formed according to the principle of analogues. Piglets of the first experimental group received to the general diet, a feed additive MKBA-1, consisting of Spirulina – 1 mg, dihydroquercetin – 3 mg, organic iodine – 1,5 mg per 1,5 kg of live weight per day; piglets of the second experimental group to the main diet received a feed supplement ICBA-1, consisting of Spirulina – 2 mg and dihydroquercetin – 2 mg per 3 kg of live weight per day. The use of dihydroquercetin, blue-green algae spirulina and organic iodine in various combinations in feeding piglets contributed to an increase in the adaptive ability of the body, pathogenetic reactivity and correction of metabolic processes, which provided a higher realization of the genetic potential of pigs. The introduction of feed additives into the diet of pigs contributed to an increase in the bactericidal activity of blood serum in the first experimental group by 1%, in the second experimental group by 14,1%, compared with the control group. The number of white blood cells in piglets of the experimental groups was lower and red blood cells is higher compared to piglets in the control group, which was reflected in the hemoglobin content of blood, which was higher than piglets from the control group by 2% and 8,9%, respectively.

Local mineral feed additives in the rations of steers of Hereford breed

2020 ◽  
pp. 28-39
Author(s):  
M. Grigoryev ◽  
N. Chernogradskaya
Keyword(s):  
Economic Effect ◽  
Live Weight ◽  
Negative Influence ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Mineral Salts ◽  
Meat Productivity ◽  
Experimental Group ◽  
Mineral Feed Additives

Animals imported to Yakutia from other regions fall into feeding and housing conditions that differ from their usual agro-climatic conditions, which causes the problem of their adaptation. Yakutia is one of the areas where the feed of its own production has a lack of basic minerals, which affects the health and productivity of animals, which has an additional negative influence on the adaptation process of imported cattle. In order to replenish macro- and microelements in the body, it is necessary to introduce various local mineral feed additives, premixes, and use mineral salts into the ration. Under the conditions of Central Yakutia the influence of local mineral feed additives (zeolite of the Khonguruu Deposit in the Suntar district and sapropels of local lakes) containing macro- and microelements that increase the meat productivity of steers has been studied. As a result of the research the influence of local mineral feed additives on meat productivity and physiological condition of Hereford steers has been established. Influence of zeolite and sapropel in a complex with mineral salts on digestibility of nutrients of the ration and use of nitrogen, calcium and phosphorus by experimental animals has been defined. The influence of feed additives on the quality of meat products has been studied. The results have shown that the use of local mineral feed additives in the composition of ration of steers during the fattening period at a dose of 0,7 g zeolite per 1 kg of live weight of the animal and 200 g of sapropel in combination with 10 g of mineral salts contributed to the gain in live weight, carcass weight, carcass yield, yield of edible parts, and economic efficiency of fattening. For the entire period of the experiment the gain in live weight in groups was: in control group 2222,9 kg, in the 1st experimental group 2396,2 kg, in the 2nd experimental group 2471,1 kg. The total economic effect for the 1st experimental group for the period of experiment amounted to 44,3 thousand Rubles, for the 2nd experimental group 78,0 thousand Rubles or per 1 head/day 14,06 and 24,76 Rubles, respectively.

The effectiveness of use of enterosorbent Shelltic Es when rearing of young pigs

2020 ◽  
pp. 3-11
Author(s):  
S. Grikshas ◽  
N. Kulmakova ◽  
K. Spitsyna ◽  
A. Dar’in ◽  
T. Mittelshtein
Keyword(s):  
Average Daily Gain ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Internal Organs ◽  
Feed Digestibility ◽  
Young Pigs ◽  
Carcinogenic Effects ◽  
Experimental Group

Mycotoxins have been formed in feed are secondary metabolites of fungi and are quite stable substances that have teratogenic, mutagenic and carcinogenic effects. An effective way to combat mycotoxins in feed is the use of feed additives that adsorb toxins, prevent their absorption in the gastrointestinal tract of the animal and are excreted from the body. The infl uence of coconut enterosorbent Shelltic Es on fattening and meat qualities of young pigs has been studied. It has been found in the process of fattening that the highest feed digestibility was in pigs of the experimental group, in the diet of which enterosorbent has been added. The results of studies of the chemical composition and technological properties of pork have been provided. The positive eff ect of enterosorbent on precocity, absolute average daily gain of live weight and reduction of feed expenditures per 1 kg of gain has been revealed. In pigs from the experimental group the average thickness of the fat was higher and the area of the “muscle eye” was lower compared with animals of the control group, which indicates that higher rates of carcass yield have been obtained due to faster accumulation of fat tissue. The weight of internal organs of pigs indicates the intensity of metabolic processes in the body. In experimental animals the weight of the lungs was 0,1 kg lower, and the liver and heart were higher by 0,13 and 0,01 kg, respectively. Enterosorbent had no effect on the content of vitamins in the liver of pigs of the compared groups. The content of impurities of organochlorine toxicants and toxic elements in the meat and liver of animals of the experimental group was lower than that of control analogues. Therefore, the use of enterosorbent Shelltic Es promotes more active excretion of them from the body.

scholarly journals Treatment of cattle pyroplasmidosis in the conditions of Dagestan Republic

2021 ◽  
Vol 344 (5) ◽  
pp. 8-10
Author(s):  
S. Sh. Abdulmagomedov ◽  
A. Yu. Aliev ◽  
R. M. Bakrieva ◽  
E. A. Belkin
Keyword(s):  
Live Weight ◽  
The Body ◽  
Control Measures ◽  
Ixodid Ticks ◽  
Farm Animals ◽  
Blood Parasites ◽  
Control Group ◽  
Single Intramuscular Injection ◽  
Short Time ◽  
And Control

Relevance. Dagestan Republic in terms of natural and climatic characteristics is the most favorable for the of ixodid ticks - carriers of pathogens of blood-parasitic diseases of farm animals. In this regard, further improvement of the set of scientifically grounded control measures and the search for new promising chemotherapeutic drugs of the prevention and treatment of pyroplasmidosis of cattle are major problem of great national economic importance.Materials and methods. The studies were carried out in farms, unfavorable on pyroplasmidosis, in the conditions of Dagestan Republic. The object of the study was cattle, spontaneously invaded by various types of blood parasites. Experеmental and control groups in production experiments were selected according to the principle of analogues. In the first control group (n = 10) the drug was not used. The second (n = 10) was injected with the drug DAC 5% at a dose of 1 ml/20 kg (DV 2.5 mg/kg), intramuscularly, at the rate 5 ml per 100 kg of live weight. The animals of the third (n = 10) were injected with the injectable preparation forticarb 10% at a dose of 4 ml/100 kg (DV 4 mg/kg) of live weight, intramuscularly, once.Results. It was found that with a single intramuscular injection of forticarb at the rate 2 ml/50 kg of live weight, the temperature and parasitic reaction in the body of sick animals decreased in a very short time. Therapeutic efficacy in pyroplasmidosis of cattle was 90%.

COMPARATIVE ASSESSMENT OF THE FUNCTIONAL PROPERTIES OF THE FOOD ADDITIVE «TOMATNAYA» OBTAINED BY VARIOUS TECHNOLOGIES

2021 ◽  
Author(s):  
Е.П. ВИКТОРОВА ◽  
Е.В. ЛИСОВАЯ ◽  
М.В. ЛУКЬЯНЕНКО ◽  
Н.Н. КОРНЕН ◽  
Е.В. КУЗЬМИНОВА ◽  
...  
Keyword(s):  
Functional Properties ◽  
Antioxidant Properties ◽  
Food Additive ◽  
The Body ◽  
Innovative Technology ◽  
Control Group ◽  
Standard Diet ◽  
Tomato Pomace ◽  
White Rats ◽  
Experimental Group

Для получения препаратов и добавок, обладающих антиоксидантными свойствами, представляют интерес выжимки томатов, образующиеся при производстве сока прямого отжима с предварительным отделением семян. Проведена сравнительная оценка эффективности функциональных свойств образцов пищевой добавки, полученных из выжимок томатов по различным технологиям: образец добавки 1 получен по технологии, включающей ИК-сушку выжимок, их охлаждение и измельчение; образец добавки 2 – по инновационной технологии, включающей дополнительную предварительную обработку выжимок в ЭМП СВЧ перед ИК-сушкой. Исследования проводили в течение 30 дней на трех группах лабораторных белых крыс: контрольной, животные которой получали стандартный рацион, и двух опытных, в которых животные помимо основного рациона получали при кормлении индивидуально 1 раз в сутки 2 г добавки образца 1 (1-я опытная группа) или образца 2 (2-я опытная группа). Установлено, что степень снижения концентрации ферментов печени АсАт и АлАт в крови животных 2-й опытной группы соответственно на 10,6 и 11,0% выше, чем в крови животных 1-й опытной группы. Степень снижения содержания диеновых коньюгатов, кетодиенов и малонового диальдегида в крови животных 2-й опытной группы была соответственно на 22,1; 10,1 и 12,7% выше по сравнению с аналогичными показателями животных 1-й опытной группы. Таким образом, доказано, что пищевая добавка «Томатная», выработанная по инновационной технологии, проявляет ярко выраженные антиоксидантные и гепатопротекторные свойства, что обеспечивает нормализацию биохимических процессов в организме, повышает его антиоксидантную защиту и препятствует разрушению мембран клеток. For the obtaining of preparations and additives with antioxidant properties, tomato pomace, formed during the production of direct-pressed juice with preliminary separation of seeds, is of interest. A comparative evaluation of the effectiveness of the functional properties of food additive samples obtained from tomato pomace using various technologies was carried out. The sample of additive 1 was obtained using a technology that includes IR drying of pomace, cooling and grinding; the sample of additive 2 was obtained using a technology that includes additional pretreatment of pomace in microwave EMF before IR drying. The studies were carried out for 30 days on three groups of laboratory white rats: a control group, the animals of which were given a standard diet, and two experimental ones, in which the animals, in addition to the main diet, were given individually once a day with 2 g of an additive of sample 1 (1st experimental group) or sample 2 (2nd experimental group). It was found that the degree of decrease in the concentration of liver enzymes AsAt and AlAt in the blood of animals of the 2nd experimental group was respectively 10,6 and 11,0% higher, than in the blood of animals of the 1st experimental group. The degree of decrease in the content of diene conjugates, ketodienes and malondialdehyde in the blood of animals of the 2nd experimental group was higher respectively by 22,1; 10,1 and 12,7% compared with similar indicators of animals of the 1st experimental group. Thus, it is proved that the food additive «Tomatnaya», developed by innovative technology, shows pronounced antioxidant and hepatoprotective properties, which ensures the normalization of biochemical processes in the body, increases its antioxidant protection and prevents the destruction of cell membranes.

scholarly journals The effect of sodium selenite and feed additive “Metisevit plus” on the protein-synthesizing function and functional state of the liver of rats under prolonged cadmium and lead loading

2020 ◽  
Vol 22 (100) ◽  
pp. 54-59
Author(s):  
S. О. Slobodian ◽  
B. V. Gutyj ◽  
D. F. Gufriy ◽  
P. S. Hnativ ◽  
S. D. Murska
Keyword(s):  
Liver Function ◽  
Functional State ◽  
Total Protein ◽  
Sodium Selenite ◽  
The Body ◽  
Feed Additive ◽  
Control Group ◽  
Physiological Values ◽  
Cadmium And Lead ◽  
Experimental Group

In the conditions of modern technogenic pollution of the environment, environmental problems, improving the quality of livestock products and their food safety is an important and urgent issue today. Pollution of the environment with heavy metals due to man-made activities of the population has led to a number of problems of agricultural production. The aim of the study was to investigate the effect of sodium selenite and feed additive “Metisevit plus” on the protein-synthesizing function and functional state of the liver of rats in lead-cadmium intoxication. It was found that the level of total protein in the blood of rats exposed to cadmium and lead was reduced. These changes were due to a decrease in albumin levels and an increase in globulin levels. Thus, hypoproteinemia resulting from cadmium and lead poisoning may indicate impaired hepatic protein synthesis. Transamination enzymes play a major role in the relationship between protein and carbohydrate metabolism, which is important for switching the oxidation of energy substrates from glucose to amino acid energy nutrition, which is extremely important under the influence of various environmental factors. The most active transaminases are aspartate aminotransferase and alanine aminotransferase. In the study of the activity of aminotransferases in the serum of rats treated with lead acetate and cadmium chloride, an increase in the activity of enzymes in all periods of the study. The highest activity of aminotransferases was on days 21 and 28 of the experiment in the control group of rats, which carried out the combined load of cadmium and lead. Thus, the load of the body of animals with cadmium and lead contributes to the violation of the functional state and protein-synthesizing function of the liver of animals of the experimental groups. With the introduction of sodium selenite into the body of rats, the activity of ALT and AST in the serum of the first experimental group was slightly reduced compared with the control group. However, the activity of these enzymes did not reach physiological values. When setting the feed additive “Metisevit plus” throughout the experiment, it was found that the activity of aminotransferases in the serum of rats of the second experimental group ranged within physiological values. This is due to the hepatoprotective effect of the components of the feed additive “Metisevit Plus”. In the study of protein-synthesizing function of rat liver in experimental lead-cadmium toxicosis, it was found that after application to rats of the first experimental group of sodium selenite on days 14, 21 and 28, the level of total protein in serum gradually increased, but did not reach physiological values. Using the feed supplement “Metisevit plus” rats of the second experimental group, found a slightly higher level of total protein in their blood, which on the 28th day of the experiment reached physiological values and, accordingly, amounted to 66.8 ± 1.99 g/l. It should be noted that when administering the feed additive “Metisevit plus” protein-synthesizing liver function and liver function of rats of the second experimental group were restored faster than when administering sodium selenite to the first experimental group.

scholarly journals Influence of the probiotic preparation “Plantarum” in the diets of pregnant animals on the growth and development of young animals

2021 ◽  
Vol 37 ◽  
pp. 00143
Author(s):  
Irina Funk ◽  
Nikolay Vladimirov ◽  
Alexander Yashkin ◽  
Lyudmila Pautova ◽  
Vitaly Gorshkov
Keyword(s):  
Body Weight ◽  
Growth And Development ◽  
The Body ◽  
Control Group ◽  
Standard Diet ◽  
Absolute Increase ◽  
Probiotic Preparation ◽  
Positive Effect ◽  
Experimental Group ◽  
Different Doses

The work aims to study the effect of different doses of the experimental probiotic preparation “Plantarum” when fed to pregnant animals on their reproductive qualities, as well as on the growth and development of young animals. To obtain young animals, four groups of goats were formed in the type of the Saanen breed, 20 heads each. In the first (control) group, the animals received a standard diet, in the diet of the animals of the second, third and fourth groups in the second half of pregnancy, the probiotic preparation “Plantarum” was additionally introduced, containing Lactobacillus Plantarum, Propiobacterium freudenreihii, in dosages from 0.4 to 0.8 ml/kg of body weight per day. From the offspring of the goats of the experimental groups, four groups of 12 goats were formed. The highest percentage of preservation (94%) and the highest business output of kids per 100 queens (150%) were observed in the fourth experimental group (0.8 ml). The goats of the second, third and fourth groups exceeded the body weight of their contemporaries from the control group by 3%, 6.3%, and 8.8%. The highest indices of the absolute increase in body weight by age periods were noted in the fourth group of goats. There were no significant differences in body build indices during the experiment between the goats of the control and experimental groups. Thus, the maximum positive effect was observed with the introduction of a probiotic preparation into the diet of pregnant goats at a dose of 0.8 ml/kg of body weight per day.

scholarly journals Physiological state and productivity of young pigs for probiotic action

2018 ◽  
Vol 20 (92) ◽  
pp. 68-72
Author(s):  
V. V. Voronyak ◽  
K. Y. Leskiv ◽  
V. O. Huberuk
Keyword(s):  
Physiological State ◽  
Average Daily Gain ◽  
The Body ◽  
Economic Losses ◽  
Control Group ◽  
Large White ◽  
Young Pigs ◽  
White Breed ◽  
The Impact ◽  
Experimental Group

Due to the impact of adverse environmental factors, unsatisfactory conditions of pig population, deterioration of food supply, abuse of antibiotics, lack of preventive measures, leads to the development of diseases among pigs, especially young, which leads to a decrease in resistance, body performance, reproduction and reduction of livestock, as well as large economic losses. The use of bacterial preparations from living microorganisms can significantly reduce or even eliminate the use of antibiotics and hormones in the cultivation of healthy animals, to obtain high-quality and safe high-grade products. The aim of the work is to study the effect of probiotic EM – 1 on the physiological state and productivity of young pigs of large white breed. The experiment was conducted on two groups (6 heads each) of animals-analogues, starting from 60 days of age, for 2 months. Animals of the control group received feed produced in the farm. Piglets of the experimental group in addition to the main diet received 5% of feed fermented with em-1. Evaluation of the physiological state and productivity of young pigs was carried out on 60, 90 and 120 days of experience according to the methods adopted in clinical practice. Hygienic, hematological, biochemical, zootechnical and statistical methods of research were used in the performance of the work. The use of probiotic EM-1 in animals of the experimental group led to an increase in hemoglobine concentration by 7.7%, an increase in the number of red blood cells by 13.7%, the total number of leukocytes by 9.52%, and glucose concentration by 11.4%. The advantage of the viability of these pigs for the content of total protein (P < 0.05), γ–globulins by 18.6%, the activity of aminotransferases (AlАT, AsAT; P < 0.05), the average daily gain increased by 12.3% at the end of the experiment. For feeding piglets feed with probiotic EM-1 increased metabolic processes, resistance and productivity of the body, which indicates a higher level of redox reactions in their body.

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