Comparative Clinical Signs of Herpetic Infection Coupled with HIV Infection

2020 ◽  
Keyword(s):  
Hiv Infection ◽  
Clinical Signs ◽  
Herpetic Infection

Health and social problems associated with HIV infection and AIDS in the professional activity of specialists with secondary medical education

2020 ◽  
pp. 5-13
Author(s):  
L. Guseva
Keyword(s):  
Medical Education ◽  
Hiv Infection ◽  
Clinical Signs ◽  
Modern Society ◽  
Progressive Increase ◽  
Professional Activity ◽  
Infected People ◽  
Immunodeficiency Virus ◽  
Epidemiological Characteristics

The article considers urgent problem of modern society – progressive increase in the number of people infected with the human immunodeficiency virus (HIV). Epidemiological characteristics of the pathogen are given, clinical signs of the disease and a modern strategy aimed at reducing the number of infected people are presented. The role of specialists with secondary medical education in the implementation of the Strategy aimed at combating the spread of HIV infection epidemic in the Russian Federation is emphasized.

scholarly journals Retrospective diagnosis of acute phase of HIV-infection

2001 ◽  
Vol 82 (6) ◽  
pp. 417-420
Author(s):  
D. K. Bashirova ◽  
I. M. Khaertynova ◽  
O. M. Romanenko ◽  
F. K. Sirazieva ◽  
E. A. Zamyatina
Keyword(s):  
Hiv Infection ◽  
Retrospective Analysis ◽  
Clinical Manifestations ◽  
Medical Advice ◽  
Case Histories ◽  
Acute Hiv Infection ◽  
Retrospective Diagnosis ◽  
Herpetic Infection ◽  
Acute Hiv ◽  
Expected Increase

The retrospective analysis of case histories of HIV- infected persons is carried out. It is established that in 62 patients there were clinical manifestations of acute HIV-infection: lymphadenopathy (60%), fever (71,2%), eruption (6,5%), diarrhea (3%), herpetic infection (3%), body mass decrease (30%), neurologic symptomatology. The growth of the number of persons with fresh" infections HIV is noted in Kazan and in most regions of Tatarstan Republic. Expected increase of persons with acute stages of HIV infection taking medical advice demands being on guard of medical workers of various specialities.

scholarly journals Clinical profile and factors associated with COVID-19 in Yaounde, Cameroon: A prospective cohort study

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251504
Author(s):  
Nicole Fouda Mbarga ◽  
Emilienne Epee ◽  
Marcel Mbarga ◽  
Patrick Ouamba ◽  
Herwin Nanda ◽  
...  
Keyword(s):  
Cohort Study ◽  
Hiv Infection ◽  
Respiratory Distress ◽  
Lung Disease ◽  
Disease Severity ◽  
Prospective Cohort ◽  
Age Groups ◽  
Clinical Signs ◽  
Male Gender ◽  
Factors Associated

Background A year after the COVID-19 pandemic started, there are still few scientific reports on COVID-19 in Africa. This study explores the clinical profiles and factors associated with COVID-19 in Cameroon. Materials and methods In this prospective cohort study, we followed patients admitted for suspicion of COVID-19 at Djoungolo Hospital between 01st April and 31st July 2020. Patients were categorised by age groups and disease severity: mild (symptomatic without clinical signs of pneumonia), moderate (with clinical signs of pneumonia without respiratory distress) and severe cases (clinical signs of pneumonia and respiratory distress not requiring invasive ventilation). Demographic information and clinical features were summarised. Multivariable analysis was performed to predict risk. Findings A total of 313 patients were admitted during the study period; 259 were confirmed cases of COVID-19 by Polymerase Chain Reaction (PCR). Among the confirmed cases, the male group aged 40 to 49 years (13.9%) was predominant. Disease severity ranged from mild (26.2%; n = 68) to moderate (59%; n = 153) to severe (14.7%; n = 38); the case fatality rate was 1% (n = 4). Dysgusia (46%; n = 119) and hyposmia/anosmia (37.8%; n = 98) were common features of COVID-19. Nearly one-third of patients had comorbidities (29%; n = 53), of which hypertension was the most common (18.9%; n = 49). Participation in mass gatherings (Odds Ratio (OR) = 2.37; P = 0.03) and dysgusia (OR = 2.09, P = 0.02) were predictive of diagnosis of COVID-19. Age groups 60 to 69 (OR = 7.41; P = 0.0001), 50 to 59 (OR = 4.09; P = 0.03), 40 to 49 (OR = 4.54; P = 0.01), male gender (OR = 2.53; P = 0.04), diabetes (OR = 4.05; P = 0.01), HIV infection (OR = 5.57; P = 0.03), lung disease (OR = 6.29; P = 0.01), dyspnoea (OR = 3.70; P = 0.008) and fatigue (OR = 3.35; P = 0.02) significantly predicted COVID-19 severity. Conclusions Most COVID-19 cases in this study were benign with low fatality. Age (40–70), male gender, HIV infection, lung disease, dyspnoea and fatigue are associated with severe COVID-19. Such findings may guide public health decision-making.

scholarly journals Incidence of HIV-infected infants born to HIV- infected mothers with prophylactic therapy: Preliminary report of hospital birth cohort study

2016 ◽  
Vol 46 (5) ◽  
pp. 209
Author(s):  
Nia Kurniati ◽  
T Nilamsari ◽  
Arwin AP Akib
Keyword(s):  
Cohort Study ◽  
Hiv Infection ◽  
Hiv Transmission ◽  
Transmission Rate ◽  
Clinical Signs ◽  
Birth Cohort Study ◽  
First Child ◽  
The Status ◽  
Prophylaxis Therapy ◽  
Almost All

Background Human immunodeficiency virus (HIV) is expandingrapidly and was reported double in several places in Indonesia Toour knowledge, reports regarding HIV-infected infants are stillscarce.Objectives To investigate the incidence of HIV-infected infantsborn to HIV- mothers who had received prophylaxis therapy at birth.Methods A prospective hospital-based cohort study was held fromJanuary 2003 until December 2004 in Cipto Mangunkusumo Hos-pital, Jakarta. The inclusion criteria were mothers with positive HIVand their infants had been given anti retroviral (ARV) therapy. Thebabies were followed up monthly and the status of infection wasdetermined by PCR at the age of 4 weeks and 6 months. Outcomewas measured based on PCR assays or clinical signs of HIV in-fection.Results The mothers’ age ranged from 19 to 27 years. All of themwere carrying their first child and only 41% mothers took ARV pro-phylaxis. Almost all mothers underwent caesarean section and theinfants had formula feeding. HIV infection was diagnosed in 7 in-fants and 2 of them had RNA assays more than 5,000 copies/ml.Six infants were negatives whereas 3 infants were diagnosed asindeterminate HIV infection and needed further examination. Oneneeded no further investigation as the mother was seronegative.Conclusions Preventing HIV transmission from mother to infantcan be done by giving ARV during prenatal, intrapartum, and post-natal period to the newborn. In our hospital, transmission was con-firmed in 6 of 17 infants. Unison protocol must be used and popu-lation of HIV-pregnant mother must be registered in order to knowhow high the transmission rate among Indonesian HIV people

scholarly journals Method of forecasting the probability of progression of the clinical 37 stage of HIV infection

2013 ◽  
Vol 18 (2) ◽  
pp. 37-39
Author(s):  
P. A Zatoloka ◽  
M. L Dotsenko
Keyword(s):  
Hiv Infection ◽  
High Probability ◽  
Clinical Stage ◽  
Clinical Signs ◽  
Posterior Wall ◽  
Bacteriological Examination ◽  
Mucosal Membrane ◽  
Colony Forming Units

The method of forecasting the probability of progressing of clinical stage of HIV-infection has been developed. The method includes bacteriological examination of mucosal membrane scrapings from the posterior wall of oropharynx in HIV-infected patients without clinical signs of disease of the pharynx, and the counting of fungi of the Genus Candida. In identifying the fungi of the genus Candida in the number of colony-forming units equal to or more than 103, the high probability which is 0.95 (forecasting of the positive the result) of transition of the clinical stage of HIV infection within the next 6 months into following clinical stage of the disease is stated,

scholarly journals Screening clinical signs of TB in HIV-infected convicts in correctional facilities federal penitentiary servicе

2021 ◽  
Vol 12 (4) ◽  
pp. 87-97
Author(s):  
V. S. Borovitsky
Keyword(s):  
Hiv Infection ◽  
Clinical Manifestation ◽  
Roc Curve ◽  
Clinical Symptoms ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Correctional Facility ◽  
Correctional Facilities ◽  
Infection Age ◽  
High Degree

Aim. To identify the main clinical signs that make it possible to further detect the development of tuberculosis in patients with HIV infection in a correctional facility of the Federal Penitentiary Service with a high degree of probability.Materials and methods: 569 patients with tuberculosis, 363 with HIV infection, and 206 prisoners without HIV infection. Age: from 18 to 62 years old.Results. In this study, we have identified highly probable clinical symptoms in HIV-infected prisoners in the presence of tuberculosis and weakness, cough, clinical manifestations of mycosis, hepatomegaly and lymphadenopathy. The sensitivity of detecting tuberculosis in patients with HIV infection for complaints of weakness — 61,2%, specificity — 57,3%, cough with sputum — 67,8 and 51,0%, clinical manifestation of mycosis — 95,6 and 80,6%, hepatomegaly — 48,8 and 100%, lymphadenopathy — 50,4 and 100,0%, respectively. The combined combination of these clinical manifestations gives a sensitivity of 94,6% with 81,9% specificity. The percentage of correctly classified cases according to this model is 88,93%, with the area under the ROC curve (AUC) — 0,963.

Clinical signs and symptoms in the assessment of immunodeficiency in men with subtype C HIV infection in Harare, Zimbabwe

2002 ◽  
Vol 3 (2) ◽  
pp. 148-154 ◽  
Author(s):  
Rhoderick Machekano ◽  
Mary Bassett ◽  
Willi McFarland ◽  
David Katzenstein
Keyword(s):  
Hiv Infection ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Subtype C ◽  
Clinical Signs And Symptoms

scholarly journals CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF PATIENTS WITH HIV INFECTION

2019 ◽  
Vol 19 (3) ◽  
pp. 3-6
Author(s):  
M.O. Andrushchak ◽  
V.D. Moskaliuk ◽  
I.V. Balaniuk ◽  
I.V. Rudan
Keyword(s):  
Weight Loss ◽  
Hiv Infection ◽  
Clinical Stage ◽  
Clinical Signs ◽  
Hiv Positive ◽  
Chronic Diarrhoea ◽  
Hiv Status ◽  
Hiv Viral Load ◽  
Study Results ◽  
Epidemiological Characteristics

According to the latest data, in early 2018, 75% of HIV-positive people in the world knew about their HIV status (70% in early 2017); 79% of those who knew about their HIV status received treatment, 81% of those who received antiretroviral therapy have achieved an undetectable level of HIV viral load in the blood, i.e. less than 1000 RNA copies / ml. The purpose of the work is to find out the current clinical and epidemiological features of HIV infection, including in the Bukovina region. Materials and Methods: this prospective study for 2016 – 2018 included 292 HIV patients undergoing outpatient monitoring at the Chernivtsi Regional Center for AIDS Prevention and Control. All the subjects gave voluntary informed consent to participate in the study. Results and Discussion: Young people (25 – 44 years old) were predominantly included in the study; their total share among men was 88.3% and among women – 76.0%. There were slightly more female patients under 24 years of age (10.6% of female individuals versus 4.3% of male individuals) and within the 45-55 year old group (13.4% female participants versus 7.4% of male individuals). Clinical signs of stage III HIV infection found in 108 people included the manifestations of general intoxication syndrome forcing the participants to stay down in the bed up to a half a day. All the participants demonstrated the weight loss over 10% of that initially established; 34 (31.5%) patients had "unexplained" chronic diarrhoea over 3 times a day, which lasted more than a month. For 118 HIV-positive patients of the IV clinical stage, the fatigue syndrome (unexplained weight loss (more than 10% for 6 months) was the most indicative; this condition forced them to stay in bed for more than a half a day. Conclusions: Markers of hemocontact viral hepatitis were detected in 59.1% of patients with clinical stage I and II HIV infection, in 55.6% of the patients with III stage HIV and in 61.0% with stage IV of the disease.

scholarly journals Modern death risk factors in patients with community-acquired pneumonia

2012 ◽  
Vol 93 (5) ◽  
pp. 816-820
Author(s):  
L V Povalyaeva ◽  
B E Borodulin ◽  
E A Borodulina ◽  
G Y Chernogaeva ◽  
E S Chumanova
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Hiv Infection ◽  
Clinical Signs ◽  
Community Acquired Pneumonia ◽  
Arterial Hypotension ◽  
Control Group ◽  
Study Group ◽  
Death Risk ◽  
Lung Lobe

Aim. To study death risk factors in patients with community-acquired pneumonia in municipal hospitals in Samara. Methods. 75 cases of deaths of patients hospitalized because of community-acquired pneumonia were studied (study group), 300 convalescent patients with community-acquired pneumonia discharged from the hospital were included in the control group. The retrospective comparative «case control» study was performed. Results. Mean age of the patients who died was 47.4±2.2 years; men were more prevalent (70.6%), time since admission date till death was 6.5±2.5 days, more than a third (36.0%) died before 24 hours after admission. The study group contained significantly higher number of unemployed (72.0%) and intravenous drugs users (16.0%). HIV infection was found in 37.3% of the patients who died, compared to 19.6% prevalence in control group. Multifactorial logistic regression of clinical signs revealed the following death risk factors in patients with community-acquired pneumonia: infiltrates on X-ray involving more than one lung lobe, arterial hypotension (systolic blood pressure ≤100 mm Hg, diastolic blood pressure ≤60 mm Hg), tachypnea (breath rate over 25 per minute). Conclusion. Factors having the highest positive prognostic value for a lethal outcome at patients with community-acquired pneumonia are: late admission, multilobar pneumonia; arterial hypotension; tachypnea; HIV infection, social unemployment and male gender.

scholarly journals Clinical signs of tuberculosis relapses in HIV patients

2020 ◽  
Vol 98 (6) ◽  
pp. 32-35
Author(s):  
E. Yu. Zorkаltsevа ◽  
Yu. O. Egorovа
Keyword(s):  
Central Nervous System ◽  
Hiv Infection ◽  
Treatment Efficacy ◽  
Medical Records ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Hiv Positive ◽  
Hiv Patients ◽  
The Central Nervous System ◽  
Hiv Negative

The objective: to study clinical manifestations of tuberculosis relapses and their treatment outcomes in patients with HIV infection.Subjects and Methods. 132 medical records of patients with tuberculosis relapses were analyzed; 69 of them were HIV-positive and 63 were HIV-negative. All of them were admitted to Irkutsk Regional Clinical Tuberculosis Hospital from 2016 to 2019, and then continued treatment of tuberculosis on the out-patient basis. Treatment efficacy was assessed in February 2020.Results. More severe clinical forms of tuberculosis relapses were typical of HIV patients including generalized forms affecting the central nervous system. Therefore, among these patients, the mortality rate is significantly higher (24.6%) than in tuberculosis relapses with no concurrent HIV infection (6.3%), p ≤ 0.05.

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