scholarly journals Investigating Machine Learning Approaches for Bitcoin Ransomware Payment Detection Systems

2020 ◽  
Vol 5 (9) ◽  
pp. 1216-1222
Author(s):  
Kirat Jadhav
Keyword(s):  
Machine Learning ◽  
Detection Rate ◽  
Nearest Neighbor ◽  
Gradient Boosting ◽  
Learning Approaches ◽  
K Nearest Neighbor ◽  
Detection Systems ◽  
Digital World ◽  
F Measure ◽  
Machine Learning Models

Cryptocurrencies have revolutionized the process of trading in the digital world. Roughly one decade since the induction of the first bitcoin block, thousands of cryptocurrencies have been introduced. The anonymity offered by the cryptocurrencies also attracted the perpetuators of cybercrime. This paper attempts to examine the different machine learning approaches for efficiently identifying ransomware payments made to the operators using bitcoin transactions. Machine learning models may be developed based on patterns differentiating such cybercrime operations from normal bitcoin transactions in order to identify and report attacks. The machine learning approaches are evaluated on bitcoin ransomware dataset. Experimental results show that Gradient Boosting and XGBoost algorithms achieved better detection rate with respect to precision, recall and F-measure rates when compared with k-Nearest Neighbor, Random Forest, Naïve Bayes and Multilayer Perceptron approaches

scholarly journals Classification of Parkinson’s disease and essential tremor based on balance and gait characteristics from wearable motion sensors via machine learning techniques: a data-driven approach

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Sanghee Moon ◽  
Hyun-Je Song ◽  
Vibhash D. Sharma ◽  
Kelly E. Lyons ◽  
Rajesh Pahwa ◽  
...  
Keyword(s):  
Machine Learning ◽  
Nearest Neighbor ◽  
Machine Learning Techniques ◽  
Gradient Boosting ◽  
Support Vector ◽  
Motion Sensors ◽  
Learning Models ◽  
K Nearest Neighbor ◽  
Gait Characteristics ◽  
Machine Learning Models

Abstract Background Parkinson’s disease (PD) and essential tremor (ET) are movement disorders that can have similar clinical characteristics including tremor and gait difficulty. These disorders can be misdiagnosed leading to delay in appropriate treatment. The aim of the study was to determine whether balance and gait variables obtained with wearable inertial motion sensors can be utilized to differentiate between PD and ET using machine learning. Additionally, we compared classification performances of several machine learning models. Methods This retrospective study included balance and gait variables collected during the instrumented stand and walk test from people with PD (n = 524) and with ET (n = 43). Performance of several machine learning techniques including neural networks, support vector machine, k-nearest neighbor, decision tree, random forest, and gradient boosting, were compared with a dummy model or logistic regression using F1-scores. Results Machine learning models classified PD and ET based on balance and gait characteristics better than the dummy model (F1-score = 0.48) or logistic regression (F1-score = 0.53). The highest F1-score was 0.61 of neural network, followed by 0.59 of gradient boosting, 0.56 of random forest, 0.55 of support vector machine, 0.53 of decision tree, and 0.49 of k-nearest neighbor. Conclusions This study demonstrated the utility of machine learning models to classify different movement disorders based on balance and gait characteristics collected from wearable sensors. Future studies using a well-balanced data set are needed to confirm the potential clinical utility of machine learning models to discern between PD and ET.

Application of Machine Learning Approaches for the Design and Study of Anticancer Drugs

2019 ◽  
Vol 20 (5) ◽  
pp. 488-500 ◽  
Author(s):  
Yan Hu ◽  
Yi Lu ◽  
Shuo Wang ◽  
Mengying Zhang ◽  
Xiaosheng Qu ◽  
...  
Keyword(s):  
Machine Learning ◽  
Drug Design ◽  
Anticancer Drugs ◽  
Nearest Neighbor ◽  
Cost Effective ◽  
Support Vector ◽  
Learning Approaches ◽  
K Nearest Neighbor ◽  
Activity Prediction ◽  
Linear Discriminant

Background: Globally the number of cancer patients and deaths are continuing to increase yearly, and cancer has, therefore, become one of the world&#039;s highest causes of morbidity and mortality. In recent years, the study of anticancer drugs has become one of the most popular medical topics. </P><P> Objective: In this review, in order to study the application of machine learning in predicting anticancer drugs activity, some machine learning approaches such as Linear Discriminant Analysis (LDA), Principal components analysis (PCA), Support Vector Machine (SVM), Random forest (RF), k-Nearest Neighbor (kNN), and Naïve Bayes (NB) were selected, and the examples of their applications in anticancer drugs design are listed. </P><P> Results: Machine learning contributes a lot to anticancer drugs design and helps researchers by saving time and is cost effective. However, it can only be an assisting tool for drug design. </P><P> Conclusion: This paper introduces the application of machine learning approaches in anticancer drug design. Many examples of success in identification and prediction in the area of anticancer drugs activity prediction are discussed, and the anticancer drugs research is still in active progress. Moreover, the merits of some web servers related to anticancer drugs are mentioned.

scholarly journals Evaluation of Three Different Machine Learning Methods for Object-Based Artificial Terrace Mapping—A Case Study of the Loess Plateau, China

2021 ◽  
Vol 13 (5) ◽  
pp. 1021
Author(s):  
Hu Ding ◽  
Jiaming Na ◽  
Shangjing Jiang ◽  
Jie Zhu ◽  
Kai Liu ◽  
...  
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Loess Plateau ◽  
Water Conservation ◽  
Nearest Neighbor ◽  
Gradient Boosting ◽  
K Nearest Neighbor ◽  
The Loess Plateau ◽  
Object Based ◽  
Extreme Gradient Boosting

Artificial terraces are of great importance for agricultural production and soil and water conservation. Automatic high-accuracy mapping of artificial terraces is the basis of monitoring and related studies. Previous research achieved artificial terrace mapping based on high-resolution digital elevation models (DEMs) or imagery. As a result of the importance of the contextual information for terrace mapping, object-based image analysis (OBIA) combined with machine learning (ML) technologies are widely used. However, the selection of an appropriate classifier is of great importance for the terrace mapping task. In this study, the performance of an integrated framework using OBIA and ML for terrace mapping was tested. A catchment, Zhifanggou, in the Loess Plateau, China, was used as the study area. First, optimized image segmentation was conducted. Then, features from the DEMs and imagery were extracted, and the correlations between the features were analyzed and ranked for classification. Finally, three different commonly-used ML classifiers, namely, extreme gradient boosting (XGBoost), random forest (RF), and k-nearest neighbor (KNN), were used for terrace mapping. The comparison with the ground truth, as delineated by field survey, indicated that random forest performed best, with a 95.60% overall accuracy (followed by 94.16% and 92.33% for XGBoost and KNN, respectively). The influence of class imbalance and feature selection is discussed. This work provides a credible framework for mapping artificial terraces.

scholarly journals Assessing the Relation between Mud Components and Rheology for Loss Circulation Prevention Using Polymeric Gels: A Machine Learning Approach

Energies ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1377
Author(s):  
Musaab I. Magzoub ◽  
Raj Kiran ◽  
Saeed Salehi ◽  
Ibnelwaleed A. Hussein ◽  
Mustafa S. Nasser
Keyword(s):  
Machine Learning ◽  
Rheological Properties ◽  
Nearest Neighbor ◽  
Drilling Fluid ◽  
Gradient Boosting ◽  
K Nearest Neighbor ◽  
Wide Range ◽  
Machine Learning Approach ◽  
Drilling Operations

The traditional way to mitigate loss circulation in drilling operations is to use preventative and curative materials. However, it is difficult to quantify the amount of materials from every possible combination to produce customized rheological properties. In this study, machine learning (ML) is used to develop a framework to identify material composition for loss circulation applications based on the desired rheological characteristics. The relation between the rheological properties and the mud components for polyacrylamide/polyethyleneimine (PAM/PEI)-based mud is assessed experimentally. Four different ML algorithms were implemented to model the rheological data for various mud components at different concentrations and testing conditions. These four algorithms include (a) k-Nearest Neighbor, (b) Random Forest, (c) Gradient Boosting, and (d) AdaBoosting. The Gradient Boosting model showed the highest accuracy (91 and 74% for plastic and apparent viscosity, respectively), which can be further used for hydraulic calculations. Overall, the experimental study presented in this paper, together with the proposed ML-based framework, adds valuable information to the design of PAM/PEI-based mud. The ML models allowed a wide range of rheology assessments for various drilling fluid formulations with a mean accuracy of up to 91%. The case study has shown that with the appropriate combination of materials, reasonable rheological properties could be achieved to prevent loss circulation by managing the equivalent circulating density (ECD).

scholarly journals Bacterial Immunogenicity Prediction by Machine Learning Methods

Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 709
Author(s):  
Ivan Dimitrov ◽  
Nevena Zaharieva ◽  
Irini Doytchinova
Keyword(s):  
Machine Learning ◽  
Nearest Neighbor ◽  
Predictive Ability ◽  
Initial Step ◽  
Majority Voting ◽  
Gradient Boosting ◽  
Support Vector ◽  
K Nearest Neighbor ◽  
Test Set ◽  
Extreme Gradient Boosting

The identification of protective immunogens is the most important and vigorous initial step in the long-lasting and expensive process of vaccine design and development. Machine learning (ML) methods are very effective in data mining and in the analysis of big data such as microbial proteomes. They are able to significantly reduce the experimental work for discovering novel vaccine candidates. Here, we applied six supervised ML methods (partial least squares-based discriminant analysis, k nearest neighbor (kNN), random forest (RF), support vector machine (SVM), random subspace method (RSM), and extreme gradient boosting) on a set of 317 known bacterial immunogens and 317 bacterial non-immunogens and derived models for immunogenicity prediction. The models were validated by internal cross-validation in 10 groups from the training set and by the external test set. All of them showed good predictive ability, but the xgboost model displays the most prominent ability to identify immunogens by recognizing 84% of the known immunogens in the test set. The combined RSM-kNN model was the best in the recognition of non-immunogens, identifying 92% of them in the test set. The three best performing ML models (xgboost, RSM-kNN, and RF) were implemented in the new version of the server VaxiJen, and the prediction of bacterial immunogens is now based on majority voting.

PREDICTION OF CORONARY ARTERY DISEASE BASED ON ENSEMBLE LEARNING APPROACHES AND CO-EXPRESSED OBSERVATIONS

2016 ◽  
Vol 16 (01) ◽  
pp. 1640010 ◽  
Author(s):  
YING-TSANG LO ◽  
HAMIDO FUJITA ◽  
TUN-WEN PAI
Keyword(s):  
Machine Learning ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Nearest Neighbor ◽  
Prediction Method ◽  
Medical Decision ◽  
Learning Approaches ◽  
K Nearest Neighbor ◽  
Artery Disease ◽  
Voting Mechanism

Background: Coronary artery disease (CAD) is one of the most representative cardiovascular diseases. Early and accurate prediction of CAD based on physiological measurements can reduce the risk of heart attack through medicine therapy, healthy diet, and regular physical activity. Methods:Four heart disease datasets from the UC Irvine Machine Learning Repository were combined and re-examined to remove incomplete entries, and a total of 822 cases were utilized in this study. Seven machine learning methods, including Naïve Bayes, artificial neural networks (ANNs), sequential minimal optimization (SMO), k-nearest neighbor (KNN), AdaBoost, J48, and random forest, were adopted to analyze the collected datasets for CAD prediction. By combining co-expressed observations and an ensemble voting mechanism, we designed and evaluated a new medical decision classifier for CAD prediction. The TOPSIS (Technique for Order Preference by Similarity to an Ideal Solution) algorithm was applied to determine the best prediction method for CAD diagnosis. Results: Features of systolic blood pressure, cholesterol, heart rate, and ST depression are considered to be the most significant differences between patients with and without CADs. We show that the prediction capability of seven machine learning classifiers can be enhanced by integrating combinations of observed co-expressed features. Finally, compared to the use of any single classifier, the proposed voting mechanism achieved optimal performance according to TOPSIS.

scholarly journals Ability of a Machine Learning Algorithm to Predict the Need for Perioperative Red Blood Cells Transfusion in Pelvic Fracture Patients: A Multicenter Cohort Study in China

2021 ◽  
Vol 8 ◽  
Author(s):  
Xueyuan Huang ◽  
Yongjun Wang ◽  
Bingyu Chen ◽  
Yuanshuai Huang ◽  
Xinhua Wang ◽  
...  
Keyword(s):  
Machine Learning ◽  
Cohort Study ◽  
Random Forest ◽  
Blood Cells ◽  
Nearest Neighbor ◽  
Learning Algorithm ◽  
Kappa Coefficient ◽  
Gradient Boosting ◽  
Machine Learning Algorithm ◽  
K Nearest Neighbor

Background: Predicting the perioperative requirement for red blood cells (RBCs) transfusion in patients with the pelvic fracture may be challenging. In this study, we constructed a perioperative RBCs transfusion predictive model (ternary classifications) based on a machine learning algorithm.Materials and Methods: This study included perioperative adult patients with pelvic trauma hospitalized across six Chinese centers between September 2012 and June 2019. An extreme gradient boosting (XGBoost) algorithm was used to predict the need for perioperative RBCs transfusion, with data being split into training test (80%), which was subjected to 5-fold cross-validation, and test set (20%). The ability of the predictive transfusion model was compared with blood preparation based on surgeons' experience and other predictive models, including random forest, gradient boosting decision tree, K-nearest neighbor, logistic regression, and Gaussian naïve Bayes classifier models. Data of 33 patients from one of the hospitals were prospectively collected for model validation.Results: Among 510 patients, 192 (37.65%) have not received any perioperative RBCs transfusion, 127 (24.90%) received less-transfusion (RBCs &lt; 4U), and 191 (37.45%) received more-transfusion (RBCs ≥ 4U). Machine learning-based transfusion predictive model produced the best performance with the accuracy of 83.34%, and Kappa coefficient of 0.7967 compared with other methods (blood preparation based on surgeons' experience with the accuracy of 65.94%, and Kappa coefficient of 0.5704; the random forest method with an accuracy of 82.35%, and Kappa coefficient of 0.7858; the gradient boosting decision tree with an accuracy of 79.41%, and Kappa coefficient of 0.7742; the K-nearest neighbor with an accuracy of 53.92%, and Kappa coefficient of 0.3341). In the prospective dataset, it also had a food performance with accuracy 81.82%.Conclusion: This multicenter retrospective cohort study described the construction of an accurate model that could predict perioperative RBCs transfusion in patients with pelvic fractures.

scholarly journals Predicting Fine Particulate Matter (PM2.5) in the Greater London Area: An Ensemble Approach using Machine Learning Methods

2020 ◽  
Vol 12 (6) ◽  
pp. 914 ◽  
Author(s):  
Mahdieh Danesh Yazdi ◽  
Zheng Kuang ◽  
Konstantina Dimakopoulou ◽  
Benjamin Barratt ◽  
Esra Suel ◽  
...  
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Nearest Neighbor ◽  
Meteorological Data ◽  
Fine Particulate Matter ◽  
Gradient Boosting ◽  
K Nearest Neighbor ◽  
Learning Methods ◽  
Machine Learning Methods ◽  
Technological Advances

Estimating air pollution exposure has long been a challenge for environmental health researchers. Technological advances and novel machine learning methods have allowed us to increase the geographic range and accuracy of exposure models, making them a valuable tool in conducting health studies and identifying hotspots of pollution. Here, we have created a prediction model for daily PM2.5 levels in the Greater London area from 1st January 2005 to 31st December 2013 using an ensemble machine learning approach incorporating satellite aerosol optical depth (AOD), land use, and meteorological data. The predictions were made on a 1 km × 1 km scale over 3960 grid cells. The ensemble included predictions from three different machine learners: a random forest (RF), a gradient boosting machine (GBM), and a k-nearest neighbor (KNN) approach. Our ensemble model performed very well, with a ten-fold cross-validated R2 of 0.828. Of the three machine learners, the random forest outperformed the GBM and KNN. Our model was particularly adept at predicting day-to-day changes in PM2.5 levels with an out-of-sample temporal R2 of 0.882. However, its ability to predict spatial variability was weaker, with a R2 of 0.396. We believe this to be due to the smaller spatial variation in pollutant levels in this area.

Machine Learning Approach to Differentiation of Peripheral Schwannomas and Neurofibromas: A Multi-Center Study

2021 ◽  
Author(s):  
Michael Zhang ◽  
Elizabeth Tong ◽  
Sam Wong ◽  
Forrest Hamrick ◽  
Maryam Mohammadzadeh ◽  
...  
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Clinical Features ◽  
Nearest Neighbor ◽  
Motor Deficit ◽  
Support Vector ◽  
Spontaneous Pain ◽  
Learning Approaches ◽  
Imaging Data ◽  
K Nearest Neighbor

Abstract Background Non-invasive differentiation between schwannomas and neurofibromas is important for appropriate management, preoperative counseling, and surgical planning, but has proven difficult using conventional imaging. The objective of this study was to develop and evaluate machine learning approaches for differentiating peripheral schwannomas from neurofibromas. Methods We assembled a cohort of schwannomas and neurofibromas from 3 independent institutions and extracted high-dimensional radiomic features from gadolinium-enhanced, T1-weighted MRI using the PyRadiomics package on Quantitative Imaging Feature Pipeline. Age, sex, neurogenetic syndrome, spontaneous pain, and motor deficit were recorded. We evaluated the performance of 6 radiomics-based classifier models with and without clinical features and compared model performance against human expert evaluators. Results 107 schwannomas and 59 neurofibroma were included. The primary models included both clinical and imaging data. The accuracy of the human evaluators (0.765) did not significantly exceed the no-information rate (NIR), whereas the Support Vector Machine (0.929), Logistic Regression (0.929), and Random Forest (0.905) classifiers exceeded the NIR. Using the method of DeLong, the AUC for the Logistic Regression (AUC=0.923) and K Nearest Neighbor (AUC=0.923) classifiers was significantly greater than the human evaluators (AUC=0.766; p = 0.041). Conclusions The radiomics-based classifiers developed here proved to be more accurate and had a higher AUC on the ROC curve than expert human evaluators. This demonstrates that radiomics using routine MRI sequences and clinical features can aid in differentiation of peripheral schwannomas and neurofibromas.

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