Machine Learning Approach to Differentiation of Peripheral Schwannomas and Neurofibromas: A Multi-Center Study

2021 ◽  
Author(s):  
Michael Zhang ◽  
Elizabeth Tong ◽  
Sam Wong ◽  
Forrest Hamrick ◽  
Maryam Mohammadzadeh ◽  
...  

Abstract Background Non-invasive differentiation between schwannomas and neurofibromas is important for appropriate management, preoperative counseling, and surgical planning, but has proven difficult using conventional imaging. The objective of this study was to develop and evaluate machine learning approaches for differentiating peripheral schwannomas from neurofibromas. Methods We assembled a cohort of schwannomas and neurofibromas from 3 independent institutions and extracted high-dimensional radiomic features from gadolinium-enhanced, T1-weighted MRI using the PyRadiomics package on Quantitative Imaging Feature Pipeline. Age, sex, neurogenetic syndrome, spontaneous pain, and motor deficit were recorded. We evaluated the performance of 6 radiomics-based classifier models with and without clinical features and compared model performance against human expert evaluators. Results 107 schwannomas and 59 neurofibroma were included. The primary models included both clinical and imaging data. The accuracy of the human evaluators (0.765) did not significantly exceed the no-information rate (NIR), whereas the Support Vector Machine (0.929), Logistic Regression (0.929), and Random Forest (0.905) classifiers exceeded the NIR. Using the method of DeLong, the AUC for the Logistic Regression (AUC=0.923) and K Nearest Neighbor (AUC=0.923) classifiers was significantly greater than the human evaluators (AUC=0.766; p = 0.041). Conclusions The radiomics-based classifiers developed here proved to be more accurate and had a higher AUC on the ROC curve than expert human evaluators. This demonstrates that radiomics using routine MRI sequences and clinical features can aid in differentiation of peripheral schwannomas and neurofibromas.

2019 ◽  
Vol 20 (5) ◽  
pp. 488-500 ◽  
Author(s):  
Yan Hu ◽  
Yi Lu ◽  
Shuo Wang ◽  
Mengying Zhang ◽  
Xiaosheng Qu ◽  
...  

Background: Globally the number of cancer patients and deaths are continuing to increase yearly, and cancer has, therefore, become one of the world&#039;s highest causes of morbidity and mortality. In recent years, the study of anticancer drugs has become one of the most popular medical topics. </P><P> Objective: In this review, in order to study the application of machine learning in predicting anticancer drugs activity, some machine learning approaches such as Linear Discriminant Analysis (LDA), Principal components analysis (PCA), Support Vector Machine (SVM), Random forest (RF), k-Nearest Neighbor (kNN), and Naïve Bayes (NB) were selected, and the examples of their applications in anticancer drugs design are listed. </P><P> Results: Machine learning contributes a lot to anticancer drugs design and helps researchers by saving time and is cost effective. However, it can only be an assisting tool for drug design. </P><P> Conclusion: This paper introduces the application of machine learning approaches in anticancer drug design. Many examples of success in identification and prediction in the area of anticancer drugs activity prediction are discussed, and the anticancer drugs research is still in active progress. Moreover, the merits of some web servers related to anticancer drugs are mentioned.


MATICS ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 21-27
Author(s):  
Via Ardianto Nugroho ◽  
Derry Pramono Adi ◽  
Achmad Teguh Wibowo ◽  
MY Teguh Sulistyono ◽  
Agustinus Bimo Gumelar

Pada industri jasa pelayanan peti kemas, Terminal Nilam merupakan pelanggan dari PT. BIMA, yang secara khusus bergerak dibidang jasa perbaikan dan perawatan alat berat. Terminal ini menjadi sentral tempat untuk melakukan aktifitas bongkar muat peti kemas domestik yang memiliki empat buah container crane untuk melayani dua kapal. Proses perawatan alat berat seperti container crane yang selama ini beroperasi, agaknya kurang memperhatikan data pengelompokkan atau klasifikasi jenis perawatan yang dibutuhkan oleh alat berat tersebut. Di kemudian hari, alat berat dapat menunjukkan kinerja yang tidak maksimal bahkan dapat berujung pada kecelakaan kerja. Selain itu, kelalaian perawatan container crane juga dapat menyebabkan pembengkakan biaya perawatan lanjut. Target produksi bongkar muat dapat berkurang dan juga keterlambatan jadwal kapal sandar sangat mungkin terjadi. Metode pembelajaran menggunakan mesin atau biasa disebut dengan Machine Learning (ML), dengan mudah dapat melenyapkan kemungkinan-kemungkinan tersebut. ML dalam penelitian ini, kami rancang agar bekerja dengan mengidentifikasi lalu mengelompokkan jenis perawatan container crane yang sesuai, yaitu ringan atau berat. Metode ML yang pilih untuk digunakan dalam penelitian ini yaitu Random Forest, Support Vector Machine, k-Nearest Neighbor, Naïve Bayes, Logistic Regression, J48, dan Decision Tree. Penelitian ini menunjukkan keberhasilan ML model tree dalam melakukan pembelajaran jenis data perawatan container crane (numerik dan kategoris), dengan J48 menunjukkan performa terbaik dengan nilai akurasi dan nilai ROC-AUC mencapai 99,1%. Pertimbangan klasifikasi kami lakukan dengan mengacu kepada tanggal terakhir perawatan, hour meter, breakdown, shutdown, dan sparepart.


Diabetes is one of the prevalent diseases all over the world. As per the International Diabetes Federation (IDF) report of the year 2017, diabetes is prevalent in about 8.8% of the Indian adult population and is one of the top ten causes of death in India. In untreated and unidentified diabetes could cause fluctuations in the sugar levels and extreme cases, damage organs such as kidneys, eyes, and arteries in the heart. By using Machine learning algorithms to predict the disease from the relevant datasets at an early stage could likely save human lives. The purpose of this investigation is to assess the classifiers that can predict the probability of disease in patients with the greatest precision and accuracy. Experimental work has been carried out using classification algorithms such as K Nearest Neighbor (KNN), Decision Tree(DT), Naive Bayes (NB), Support Vector Machine (SVM), Logistic Regression (LR) and Random Forest(RF) on Pima Indians Diabetes dataset using nine attributes which is available online on UCI Repository. The performance of classifier is evaluated based on precision, recall, accuracy and is estimated over correct and incorrect instances. The results proved that Logistic Regression (LR) performs better with the accuracy of 77.6 % in comparison to other algorithms


Artificial intelligence is the technology that lets a machine mimic the thinking ability of a human being. Machine learning is the subset of AI, that makes this machine exhibit human behavior by making it learn from the known data, without the need of explicitly programming it. The health care sector has adopted this technology, for the development of medical procedures, maintaining huge patient’s records, assist physicians in the prediction, detection, and treatment of diseases and many more. In this paper, a comparative study of six supervised machine learning algorithms namely Logistic Regression(LR),support vector machine(SVM),Decision Tree(DT).Random Forest(RF),k-nearest neighbor(k-NN),Naive Bayes (NB) are made for the classification and prediction of diseases. Result shows out of compared supervised learning algorithms here, logistic regression is performing best with an accuracy of 81.4 % and the least performing is k-NN with just an accuracy of 69.01% in the classification and prediction of diseases.


2020 ◽  
pp. 471-476
Author(s):  
Gitanjali Wadhwa ◽  
Mansi Mathur

The important part of female reproductive system is ovaries. The importance of these tiny glands is derived from the production of female sex hormones and female gametes. The place of these ductless almond shaped tiny glandular organs is on just opposite sides of uterus attached with ovarian ligament. There are several reasons due to which ovarian cancer can arise but it can be classified by using different number of techniques. Early prediction of ovarian cancer will decrease its progress rate and may possibly save countless lives. CAD systems (Computer-aided diagnosis) is a noninvasive routine for finding ovarian cancer in its initial stages of cancer which can keep away patients’ anxiety and unnecessary biopsy. This review paper states us about how we can use different techniques to classify the ovarian cancer tumor. In this survey effort we have also deliberate about the comparison of different machine learning algorithms like K-Nearest Neighbor, Support Vector Machine and deep learning techniques used in classification process of ovarian cancer. Later comparing the different techniques for this type of cancer detection, it gives the impression that Deep Learning Technique has provided good results and come out with good accuracy and other performance metrics.


2022 ◽  
Vol 2161 (1) ◽  
pp. 012027
Author(s):  
Shalini Pandey ◽  
Sankeerthi Prabhakaran ◽  
N V Subba Reddy ◽  
Dinesh Acharya

Abstract With the advancement in technology, the consumption of news has shifted from Print media to social media. The convenience and accessibility are major factors that have contributed to this shift in consumption of the news. However, this change has bought upon a new challenge in the form of “Fake news” being spread with not much supervision available on the net. In this paper, this challenge has been addressed through a Machine learning concept. The algorithms such as K-Nearest Neighbor, Support Vector Machine, Decision Tree, Naïve Bayes and Logistic regression Classifiers to identify the fake news from real ones in a given dataset and also have increased the efficiency of these algorithms by pre-processing the data to handle the imbalanced data more appropriately. Additionally, comparison of the working of these classifiers is presented along with the results. The model proposed has achieved an accuracy of 89.98% for KNN, 90.46% for Logistic Regression, 86.89% for Naïve Bayes, 73.33% for Decision Tree and 89.33% for SVM in our experiment.


2021 ◽  
pp. 1-17
Author(s):  
Ahmed Al-Tarawneh ◽  
Ja’afer Al-Saraireh

Twitter is one of the most popular platforms used to share and post ideas. Hackers and anonymous attackers use these platforms maliciously, and their behavior can be used to predict the risk of future attacks, by gathering and classifying hackers’ tweets using machine-learning techniques. Previous approaches for detecting infected tweets are based on human efforts or text analysis, thus they are limited to capturing the hidden text between tweet lines. The main aim of this research paper is to enhance the efficiency of hacker detection for the Twitter platform using the complex networks technique with adapted machine learning algorithms. This work presents a methodology that collects a list of users with their followers who are sharing their posts that have similar interests from a hackers’ community on Twitter. The list is built based on a set of suggested keywords that are the commonly used terms by hackers in their tweets. After that, a complex network is generated for all users to find relations among them in terms of network centrality, closeness, and betweenness. After extracting these values, a dataset of the most influential users in the hacker community is assembled. Subsequently, tweets belonging to users in the extracted dataset are gathered and classified into positive and negative classes. The output of this process is utilized with a machine learning process by applying different algorithms. This research build and investigate an accurate dataset containing real users who belong to a hackers’ community. Correctly, classified instances were measured for accuracy using the average values of K-nearest neighbor, Naive Bayes, Random Tree, and the support vector machine techniques, demonstrating about 90% and 88% accuracy for cross-validation and percentage split respectively. Consequently, the proposed network cyber Twitter model is able to detect hackers, and determine if tweets pose a risk to future institutions and individuals to provide early warning of possible attacks.


2021 ◽  
Vol 13 (6) ◽  
pp. 3497
Author(s):  
Hassan Adamu ◽  
Syaheerah Lebai Lutfi ◽  
Nurul Hashimah Ahamed Hassain Malim ◽  
Rohail Hassan ◽  
Assunta Di Vaio ◽  
...  

Sustainable development plays a vital role in information and communication technology. In times of pandemics such as COVID-19, vulnerable people need help to survive. This help includes the distribution of relief packages and materials by the government with the primary objective of lessening the economic and psychological effects on the citizens affected by disasters such as the COVID-19 pandemic. However, there has not been an efficient way to monitor public funds’ accountability and transparency, especially in developing countries such as Nigeria. The understanding of public emotions by the government on distributed palliatives is important as it would indicate the reach and impact of the distribution exercise. Although several studies on English emotion classification have been conducted, these studies are not portable to a wider inclusive Nigerian case. This is because Informal Nigerian English (Pidgin), which Nigerians widely speak, has quite a different vocabulary from Standard English, thus limiting the applicability of the emotion classification of Standard English machine learning models. An Informal Nigerian English (Pidgin English) emotions dataset is constructed, pre-processed, and annotated. The dataset is then used to classify five emotion classes (anger, sadness, joy, fear, and disgust) on the COVID-19 palliatives and relief aid distribution in Nigeria using standard machine learning (ML) algorithms. Six ML algorithms are used in this study, and a comparative analysis of their performance is conducted. The algorithms are Multinomial Naïve Bayes (MNB), Support Vector Machine (SVM), Random Forest (RF), Logistics Regression (LR), K-Nearest Neighbor (KNN), and Decision Tree (DT). The conducted experiments reveal that Support Vector Machine outperforms the remaining classifiers with the highest accuracy of 88%. The “disgust” emotion class surpassed other emotion classes, i.e., sadness, joy, fear, and anger, with the highest number of counts from the classification conducted on the constructed dataset. Additionally, the conducted correlation analysis shows a significant relationship between the emotion classes of “Joy” and “Fear”, which implies that the public is excited about the palliatives’ distribution but afraid of inequality and transparency in the distribution process due to reasons such as corruption. Conclusively, the results from this experiment clearly show that the public emotions on COVID-19 support and relief aid packages’ distribution in Nigeria were not satisfactory, considering that the negative emotions from the public outnumbered the public happiness.


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