scholarly journals Blood Cholinesterase Level is Associated with Cognitive Function in Indonesian School-age Children Exposed to Pesticides

2020 ◽  
Vol 8 (E) ◽  
pp. 81-86
Author(s):  
Rusdy Ghazali Malueka ◽  
Andrianor Rahman ◽  
Ery Kus Dwianignsih ◽  
Andre Stefanus Panggabean ◽  
Halwan Fuad Bayuangga ◽  
...  

BACKGROUND: Pesticides are known as depressors of acetylcholinesterase (AChE) activity, resulting in the nervous system toxicity. The previous studies have described associations between AChE, a stable marker of pesticide poisoning, and cognitive performance in children. AIM: This study aimed to identify the association between blood AChE level and cognitive function in children exposed to pesticides in the Magelang Regency, Indonesia. METHODS: A cross-sectional study involving school-age children with a history of pesticide exposure in Ngablak, Magelang Regency, Central Java, Indonesia, was conducted. Blood AChE level was evaluated, and the Modified Mini–Mental State Examination for Children (MMMSEC) was used to analyze the cognitive function of the children. RESULTS: In total, 56 subjects aged between 9 and 11 years were included in this study. Median blood AChE level was 9.64 kIU/L, and 24 subjects (42.9%) had low blood AChE levels. Median MMMSEC score was 33. Eleven subjects (19.6%) were found to have abnormal cognitive function. Bivariate analysis showed that blood AChE level was associated with MMMSEC score (r = 0.343, p = 0.010). Multiple linear regression showed that blood AChE level had a positive association with cognitive function in children, assessed using the MMMSEC score (β = 0.360; p = 0.006). Further analysis showed that the attention and orientation (memory function) domains of the MMMSEC were significantly associated with blood AChE level (β: 0.371 and 0.297, respectively, p < 0.05). CONCLUSIONS: Blood AChE level, a stable marker of pesticide poisoning, was positively associated with cognitive function in children, as assessed using the MMMSEC score. In particular, the orientation and attention domains of the MMMSEC were associated with blood AChE level.

2020 ◽  
Vol 8 (3) ◽  
pp. 266-270
Author(s):  
Ekwuluo Celestine Emeka ◽  
S.I Muhammed

Motivation/Background: In 2001, non-communicable diseases (NCDs) accounted for 60 percent of 56 million deaths worldwide and 47% of global burden of disease. In all countries, evidence suggested underlying determinants of NCDs were largely same. These include increased consumption of rapidly processed energy-dense nutrient-poor foods high in fat, sugar, salt and reduced levels of physical activity. The objective of this study was to determine prevalence, pattern and determinants of fast foods consumption among school age children in Jos metropolis. Method: In this study, we used descriptive cross-sectional study and included 347 mothers or care givers with children age 6 to 12 years in our sample size. We applied structured interviewer-administered questionnaire during data collection and analyzed the data with SPSS version 21.0. Results: Prevalence of fast food consumption among school age children in Jos metropolis in the last one week is 91.1%. Knowledge of health risk associated with fast food consumption was 86.5%. Flour based fast food were most commonly consumed. We established an association between meal skipping, fast food advertisement and fast food consumption. Conclusions: We recommend the need to focus public enlightenment on health risk associated with fast food consumption among school age children. Likewise, children should be encouraged to carry home-made food to school and legislation on fast food advertisement directed at children should be enacted.


2017 ◽  
Vol 9 (1) ◽  
pp. 46
Author(s):  
Rendy Manuhutu ◽  
Dyah Umiyarni Purnamasari ◽  
Endo Dardjito

School age is the important period of human life and the quality have to be prepared well. The school age children is susceptible to malnutrition. Malnutrition among school age children will implicatethe children�s development and further potential development in that age. Food consumption levels and worm infection status are the two most affected factors to nutritional status of children school. The purpose of this research is to know the effect of energy, protein, fat and worm inflectional status to the nutritional status of SDN 01 Limpakuwus�s student in Sumbang, Banyumas. This research was cross sectional study approach,used purposive sampling with inclusion and exclusion criteria in 44 respondents. Analysis conducted by univariate, bivariate (Spearman rank) and multivariate (multiple logistic regression).Multivariate analysis showed the variables that influenced nutritional status is the level of fat consumption (p=0.022), and the variable did not affect the nutritional status are the level of energy consumption (p=0.999), protein consumption level (p=0.580), and worm infection status (p = 0.661). The suggestion is to get more food that can fulfil the energy, protein, fat needs and make the canteen in the school becomes a healthy canteen that serves healthy and nutritious meal.


2015 ◽  
Vol 7 (16) ◽  
pp. 47-56
Author(s):  
Desy Kumaladewi ◽  
Sugeng Maryanto ◽  
Galeh Septiar Pontang

Stunting is one of the effects of lack of nutrients that lasts a long time. Stunting can occur due to deficiency of macronutrients and macronutrients that play a role in the growth, such as energy, protein, vitamin A and zinc (Zn). The aim of this study was determine the relationship between the intake of energy, protein, vitamin A and zinc (Zn) and the incidences of stunting in children of school age in Candirejo Village This research was The study correlation with cross sectional approach. The population in this study were all first year students in Candirejo village. It obtained 56 children with total sampling method. Method of data taking used microtoise, digital scale and FFQ. Bivariate analysis used Pearson product moment and alternative test of Spearman rho (α=0,05) The average energy intake in children was 86.5% RDA. The average protein intake in children was 106.3% RDA. The average intake of vitamin A in children was 111.9% RDA. The average intake of zinc in children was 64.4% RDA. From 56 childs 37,5% was stunting and 62,5% no stunting. There was no relationship between the intake of energy, protein and vitamin A with the incidences of stunting (p = 0.129, p = 0.139, p = 0.200), and there was a correlation between zinc intake with the incidences of stunting (p = 0.014) There was no relationship between the intake of energy, protein and vitamin A with the incidences of stunting in children of school-age in Candirejo village. There was a relationship between zinc intake with the incidences of stunting in school-age children in the Candirejo village.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Zerihun Zerdo ◽  
Tsegaye Yohanes ◽  
Befikadu Tariku

Mass drug administration (MDA) to the most risky population including school-age children (SAC) is the central strategy to control soil-transmitted helminth (STH) infection. The present study was aimed at estimating the prevalence of STHs reinfection three months posttreatment and associated risk factors among SAC in Chencha district. A cross-sectional study design was employed from April 20 to May 5, 2015, to enroll 408 SAC. Structured questionnaire and Kato-Katz thick smear technique were used to interview parents or guardians and quantify the number of eggs per gram of stool. Pearson chi-square and logistic regression were used to assess the association between predictor variable and STH reinfection. The prevalence of STHs within three months of mass chemotherapy among SAC was 36.8% which is 93.4% of the prevalence (39.4%) before treatment. The estimated prevalence of reinfection (95%CI) forAscaris lumbricoides,Trichuris trichiura, and hookworms was 23.8% (21.1–28.2), 16.2% (12.7–20.1), and 1.0% (0.3–2.5), respectively. Children of merchant fathers were more likely to be reinfected by STHs in Chencha district. In conclusion, there is rapid reinfection after mass chemotherapy among SAC in Chencha district. Further studies should be carried out to generate cost efficient methods that can supplement mass drug administration to accelerate the control of STHs.


2014 ◽  
Vol 38 (4) ◽  
pp. 350-358 ◽  
Author(s):  
Gisela Jia ◽  
Jennifer Chen ◽  
HyeYoung Kim ◽  
Phoenix-Shan Chan ◽  
Changmo Jeung

This cross-sectional study investigated the bilingual lexical skills of 175 US school-age children (5 to18 years old) with Cantonese, Mandarin, or Korean as their heritage language (HL), and English as their dominant language. Primary study goals were to identify potential patterns of development in bilingual lexical skills over the elementary to high school time span and to examine the relation of environmental factors to lexical skills. HL and English productive lexical skills were assessed with a Picture Naming and a Verbal Fluency task. English receptive lexical skills were assessed with Peabody Picture Vocabulary Test. A survey obtained information about participants’ language use in six environmental contexts. There were age-related significant increases in both HL and English skills. However, English proficiency already had a significant lead over HL proficiency at the youngest age. English receptive lexical skills reached monolingual expectations from age 8, whereas for HL, high school age participants on average only reached the level of early elementary school monolinguals. Although more English use at home at younger ages was associated with stronger English skills, the relation did not exist for older participants. Instead, among older participants, more English use at home was associated with weaker HL skills. Children’s attendance at HL programs and visits to home countries bore little relation to HL proficiency.


2021 ◽  
Vol 9 ◽  
Author(s):  
Hongmei He ◽  
Shujun Yang ◽  
Na Qiu ◽  
Ling Qiao ◽  
Yong Ding ◽  
...  

Objective: The objective of this study is to further explore the difference between elevated blood pressure (EBP), elevated pulse pressure (EPP), and elevated mean arterial pressure (EMAP) and obesity in Chinese school-age children by sex.Methods: We performed a cross-sectional study of 935 children between 7 and 12 years old. Overweight and obesity were defined by body mass index and body composition. The multivariate logistic regression and the adjusted population attributable risk were used to assess the effects of obesity on pre-EBP/EBP, EPP, and EMAP. The interactions were used to identify the modification of obese on the relationship between related indicators of blood pressure and height or age.Results: The average age of the children included in the study was 10. Boys with overweight and obesity had higher pre-EBP/EBP, EPP, and EMAP (p &lt; 0.05). The multivariate logistic regression analysis showed that overweight and obesity had a greater impact on BP and MAP than PP, especially in boys [odds ratio (OR) &gt; 1]. Pre-EBP/EBP in 79% of boys and 76% of girls could be attributable to the visceral fat level. The interaction between BP, PP, MAP, and height or age was modestly increased in children with overweight and obesity, especially in boys.Conclusions: Independent of age and height, obesity not only increases blood pressure, it also increases mean arterial pressure and pulse pressure, and this effect is more pronounced in boys.


2020 ◽  
Author(s):  
Chunchun Gau ◽  
Tsung-Chieh Yao ◽  
Shu-Ting Gan ◽  
Syh-Jae Lin ◽  
Kuo-Wei Yeh ◽  
...  

Abstract Background: Among school-age children, the decrease of cartilage thickness (Cth) with increasing age is well known. However, the influence of body mass index (BMI), height or weight on Cth has not been revealed. Here in, we aim to establish an age- and gender-specific Cth standard reference among Asians and investigate the possible prestige of BMI, height and weight. Methods: A cross-sectional study was performed in healthy Asian children. Bilateral knees, ankles, wrists, second metacarpophalangeals (MCPs) and proximal interphalangeals (PIPs) were measured using ultrasound. The children’s height, weight and BMI were also recorded for later adjustment.Results: A total of 200 school age Asian children (including 86 girls and 114 boys, aged between 5 to 13 years-old) were investigated. Cth differences were observed in the knees, ankles, wrists, MCPs and PIPs between sexes (p<0.05), with girls having thinner cartilage thickness. While Cth decreases with increasing age ( p <0.0001, 0.039, 0.001, 0.023, 0.091 in girls’ knees, ankles, wrists, MCPs and PIPs and p = 0.002, 0.001, <0.0001, 0.001, 0.045 in boys’, respectively). Our data showed that weight, height and BMI are not the main factors contributing to Cth. A formula to calculate gender-specific cartilage thickness for Asian school age children is suggested. There was no difference in Cth after adjusting for height or weight between Asian or Caucasian group.Conclusions: A formula to calculate gender-specific cartilage thickness for Asian school age children is suggested. Height, weight and BMI were not the major contributor for Cth among school age children.


Author(s):  
Tadesse HAILU ◽  
Wondemagegn MULU ◽  
Bayeh ABERA

Background: Intestinal schistosomiasis is a disease caused by infection with one of the blood flukes called Schistosoma mansoni. The distribution of Schistosoma mansoni infection is high in Sub-Saharan Africa due to water source, sanitation and hygiene problems. This study aimed to determine the effect of water source, sanitation and hygiene on the prevalence of schistosomiasis among school-age children in Northwest Ethiopia. Methods: A cross-sectional study was conducted from Apr 2016 to Aug 2016. Children were selected by systematic random sampling and Formol Ether Concentration Technique (FECT) was used to identify Schistosoma mansoni infection. Statistical analysis was done using descriptive statistics and strength of association of schistosomiasis with determinant factors was calculated by bivariate analysis. Results: Among 333 children, 7% were infected with Schistosoma mansoni. Using surface water for drinking, poor hand wash habit and latrine utilization were significantly associated (P<0.05) with Schistosoma mansoni infection. Conclusion: Absence of safe water for bathing, washing and swimming, poor sanitation and hygiene practices were major risk factors for schistosomiasis. Therefore, health education should be given on the transmission of S. mansoni infection, pure water, sanitation and hygiene in S. mansoni endemic areas.


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