Anti-Ulcer Activities of Medicinal Plants and Natural Products

2020 ◽  
pp. 114-127
Author(s):  
Madhu Rani ◽  
Rubina Chongtham ◽  
Ajeet Singh
Keyword(s):  
Natural Products ◽  
Peptic Ulcer ◽  
Medicinal Plants ◽  
Plant Species ◽  
Health Problem ◽  
Peptic Ulcers ◽  
Mucosal Defense ◽  
The World ◽  
Prevention And Treatment

The peptic ulcer is a widespread and common health problem around the world. The major causes include generation of free radicles, decrease in mucosal defense factor, or increase in mucosal injurious factors. Various plants and their products have been known to prevent or reduce peptic ulcers. Natural products from plants are a rich resource used for centuries to cure different ailments. The use of phyto-constituents as drugs has proved to be clinically effective and less toxic than existing drugs. An attempt has been made to review some plant species and their products as phytomedicines showing promising results in prevention and treatment of peptic ulcers.

scholarly journals Antinociceptive, Anti-Inflammatory, and Antipyretic Activity of Mangrove Plants: A Mini Review

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
J. A. Shilpi ◽  
M. E. Islam ◽  
M. Billah ◽  
K. M. D. Islam ◽  
F. Sabrin ◽  
...  
Keyword(s):  
Natural Products ◽  
Biological Activity ◽  
Plant Species ◽  
Active Compound ◽  
Medicinal Uses ◽  
Antipyretic Activity ◽  
Mangrove Plants ◽  
The World ◽  
Anti Inflammatory ◽  
The Web

Mangrove plants are specialised plants that grow in the tidal coasts of tropic and subtropic regions of the world. Their unique ecology and traditional medicinal uses of mangrove plants have attracted the attention of researchers over the years, and as a result, reports on biological activity of mangrove plants have increased significantly in recent years. This review has been set out to compile and appraise the results on antinociceptive, anti-inflammatory, and antipyretic activity of mangrove plants. While the Web of Knowledge, Google Scholar, and PubMed were the starting points to gather information, other pieces of relevant published literature were also adequately explored for this purpose. A total of 29 reports on 17 plant species have been found to report such activities. While 19 reports were on the biological activity of the crude extracts, 10 reports identified the active compound(s) of various chemical classes of natural products including terpenes, steroids, and flavonoids. This review finds that antinociceptive, anti-inflammatory, and antipyretic activity appears to be widespread in mangrove plants.

scholarly journals Natural products targeting the p53 tumor suppressor-A novel approach for future cancer therapy- A review

2021 ◽  
Vol 1 (2) ◽  
pp. 167-176
Author(s):  
Ali Esmail Al-Snafi
Keyword(s):  
Natural Products ◽  
Cancer Therapy ◽  
Tumor Suppressor ◽  
Medicinal Plants ◽  
Cancer Prevention ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Novel Approach ◽  
Prevention And Treatment ◽  
Expression And Activity

Mutations of p53, a tumor suppressor gene, are known to be involved in multiplication and metastasis of tumors. A number of natural products targeted the p53-MDM2 pathway. This review is an attempt to highlight the medicinal plants that can modulate the expression and activity ofp53tumor suppression, for cancer prevention and treatment.

scholarly journals Peptic Ulcer Disease: A Brief Review of Conventional Therapy and Herbal Treatment Options

2019 ◽  
Vol 8 (2) ◽  
pp. 179 ◽  
Author(s):  
Lucija Kuna ◽  
Jelena Jakab ◽  
Robert Smolic ◽  
Nikola Raguz-Lucic ◽  
Aleksandar Vcev ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Medicinal Plants ◽  
Treatment Options ◽  
Chemical Compounds ◽  
Peptic Ulcers ◽  
H2 Receptor Antagonists ◽  
Ulcer Disease ◽  
Inflammatory Drugs ◽  
H Pylori ◽  
Major Factors

Peptic ulcer is a chronic disease affecting up to 10% of the world’s population. The formation of peptic ulcers depends on the presence of gastric juice pH and the decrease in mucosal defenses. Non-steroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori (H. pylori) infection are the two major factors disrupting the mucosal resistance to injury. Conventional treatments of peptic ulcers, such as proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists, have demonstrated adverse effects, relapses, and various drug interactions. On the other hand, medicinal plants and their chemical compounds are useful in the prevention and treatment of numerous diseases. Hence, this review presents common medicinal plants that may be used for the treatment or prevention of peptic ulcers.

scholarly journals Studies on Activities and Chemical Characterization of Medicinal Plants in Search for New Antimalarials: A Ten Year Review on Ethnopharmacology

2021 ◽  
Vol 12 ◽  
Author(s):  
Isabela P. Ceravolo ◽  
Anna C. Aguiar ◽  
Joseph O. Adebayo ◽  
Antoniana U. Krettli
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
South America ◽  
Plant Species ◽  
Artemisia Annua ◽  
Specific Treatment ◽  
Antimalarial Drugs ◽  
Blood Parasites ◽  
Malaria Parasites ◽  
Pubmed Database

Malaria is an endemic disease that affected 229 million people and caused 409 thousand deaths, in 2019. Disease control is based on early diagnosis and specific treatment with antimalarial drugs since no effective vaccines are commercially available to prevent the disease. Drug chemotherapy has a strong historical link to the use of traditional plant infusions and other natural products in various cultures. The research based on such knowledge has yielded two drugs in medicine: the alkaloid quinine from Cinchona species, native in the Amazon highland rain forest in South America, and artemisinin from Artemisia annua, a species from the millenary Chinese medicine. The artemisinin-based combination therapies (ACTs), proven to be highly effective against malaria parasites, and considered as “the last bullet to fight drug-resistant malaria parasites,” have limited use now due to the emergence of multidrug resistance. In addition, the limited number of therapeutic options makes urgent the development of new antimalarial drugs. This review focuses on the antimalarial activities of 90 plant species obtained from a search using Pubmed database with keywords “antimalarials,” “plants” and “natural products.” We selected only papers published in the last 10 years (2011–2020), with a further analysis of those which were tested experimentally in malaria infected mice. Most plant species studied were from the African continent, followed by Asia and South America; their antimalarial activities were evaluated against asexual blood parasites, and only one species was evaluated for transmission blocking activity. Only a few compounds isolated from these plants were active and had their mechanisms of action delineated, thereby limiting the contribution of these medicinal plants as sources of novel antimalarial pharmacophores, which are highly necessary for the development of effective drugs. Nevertheless, the search for bioactive compounds remains as a promising strategy for the development of new antimalarials and the validation of traditional treatments against malaria. One species native in South America, Ampelozyzyphus amazonicus, and is largely used against human malaria in Brazil has a prophylactic effect, interfering with the viability of sporozoites in in vitro and in vivo experiments.

scholarly journals Language extinction triggers the loss of unique medicinal knowledge

2021 ◽  
Vol 118 (24) ◽  
pp. e2103683118
Author(s):  
Rodrigo Cámara-Leret ◽  
Jordi Bascompte
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Indigenous Knowledge ◽  
Strong Coupling ◽  
Plant Species ◽  
Biodiversity Loss ◽  
Biocultural Diversity ◽  
Language Loss ◽  
The World

Over 30% of the 7,400 languages in the world will no longer be spoken by the end of the century. So far, however, our understanding of whether language extinction may result in the loss of linguistically unique knowledge remains limited. Here, we ask to what degree indigenous knowledge of medicinal plants is associated with individual languages and quantify how much indigenous knowledge may vanish as languages and plants go extinct. Focusing on three regions that have a high biocultural diversity, we show that over 75% of all 12,495 medicinal plant services are linguistically unique—i.e., only known to one language. Whereas most plant species associated with linguistically unique knowledge are not threatened, most languages that report linguistically unique knowledge are. Our finding of high uniqueness in indigenous knowledge and strong coupling with threatened languages suggests that language loss will be even more critical to the extinction of medicinal knowledge than biodiversity loss.

scholarly journals REVIEW ON POTENT ANTI-DIABETIC PLANTS OR HERBS FROM TRADITIONAL MEDICINE

2018 ◽  
Vol 8 (5) ◽  
pp. 92-98 ◽  
Author(s):  
Shilpa S. Kolhe ◽  
Punit R. Rachh
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Bioactive Compounds ◽  
Chemical Diversity ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum ◽  
Screening Programs ◽  
The World ◽  
Pure Compounds ◽  
Increasing Demand

This review focuses on Indian Herbal drugs and plants used in the treatment of diabetes, especially in India. Diabetes is an important human ailment afflicting many from various walks of life in different countries. diabetes is one of the major causes of death and disability in the world. Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Due to an increasing demand for chemical diversity in screening programs, seeking therapeutic drugs from natural products, interest particularly in edible plants has grown throughout the world. Botanicals and herbal preparations for medicinal usage contain various types of bioactive compounds. Phytochemicals identified from medicinal plants present an exciting opportunity for the development of new types of therapeutics for diabetes mellitus. Most prevalent among phytochemical groups are the alkaloids, glycosides, polysaccharides, and phenolics such as flavonoids, terpenoids and steroids. These include, Allium sativum, Eugenia jambolana, Momordica charantia Ocimum sanctum, Phyllanthus amarus, Pterocarpus marsupium, Tinospora cordifolia, Trigonella foenum graecum and Withania somnifera. Keywords: Phytochemicals, diabetes, standardized extracts, bioactive compounds.

scholarly journals General overview of medicinal plants: A review

2017 ◽  
Vol 6 (6) ◽  
pp. 349-351
Author(s):  
Refaz Ahmad Dar ◽  
◽  
Mohd Shahnawaz ◽  
Parvaiz Hassan Qazi ◽  
◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Plant Species ◽  
Essential Role ◽  
Microbial Growth ◽  
Traditional Medicines ◽  
Human Culture ◽  
General Overview ◽  
The World ◽  
Health Disorders

Medicinal plants have been playing an essential role in the development of human culture. As a source of medicine, Medicinal plants have always been at forefront virtually all cultures of civilizations. Medicinal plants are regarded as rich resources of traditional medicines and from these plants many of the modern medicines are produced. For thousands of years medicinal plants have been used to treat health disorders, to add flavor and conserve food and to prevent diseases epidemics. The secondary metabolites produced by the plants are usually responsible for the biological characteristics of plant species used throughout the world. The microbial growth in diverse situations is controlled by plant derived products. In this review we gave general overview of the medicinal plants.

scholarly journals COVID-19: General Strategies for Herbal Therapies

2022 ◽  
Vol 27 ◽  
pp. 2515690X2110536
Author(s):  
Samaneh Soleymani ◽  
Ayeh Naghizadeh ◽  
Mehrdad Karimi ◽  
Azadeh Zarei ◽  
Raefeh Mardi ◽  
...  
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Medicinal Plants ◽  
Nigella Sativa ◽  
Management Strategies ◽  
Future Research ◽  
Virus Binding ◽  
New Drug ◽  
Prevention And Treatment ◽  
Ammoides Verticillata

The coronavirus disease-2019 (COVID-19) pandemic started in early 2020 with the outbreak of a highly pathogenic human coronavirus. The world is facing a challenge and there is a pressing need for efficient drugs. Plants and natural compounds are a proven rich resource for new drug discovery. Considering the potential of natural products to manage the pandemic, this article was designed to provide an inclusive map of the stages and pathogenetic mechanisms for effective natural products on COVID-19. New drug discovery for the COVID-19 pandemic can encompass both prevention and disease management strategies. Preventive mechanisms that may be considered include boosting the immune response and hand hygiene in the preexposure phase; and blocking of virus binding and entry in the postexposure phase. Potential therapeutic target mechanisms include virus-directed therapies and host-directed therapies. Several medicinal plants and natural products, such as Withania somnifera (L.) Dunal and propolis for prevention; Tanacetum parthenium (L.) for treatment; and Ammoides verticillata (Desf.) Briq and Nigella sativa L. for both prevention and treatment have been found effective and are good targets for future research. The examples of phytochemical compounds that may be effective include aloin and terpenes as anti-septics; isothymol, dithymoquinone, and glycyrrhizin as inhibitors of virus binding and entry; glycyrrhizin, and berberine as replication suppressants; ginsenoside Rg1 and parthenolide as immunomodulators; and eriocitrin, rhoifolin, hesperidin, naringin, rutin, and veronicastroside as anti-complements. Recognizing different mechanisms of fighting against this virus can lead to a more systematic approach in finding natural products and medicinal plants for COVID-19 prevention and treatment.

Medicinal plants used for treatment of fever and headache in Uttarakhand state of India

2019 ◽  
Vol 26 (1) ◽  
pp. 39-44
Author(s):  
Chandra Prakash Kala ◽  
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Human Beings ◽  
Plant Use ◽  
Common Diseases ◽  
The World

The fever and headache are the most common diseases in human beings, and still, they are the cause of a large number of human deaths around the world. Historically, these diseases have been treated by using plant species. The present study, therefore, attempts to document plant use for treatment of fever and headache in the Uttarakhand state of India.

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