Preparation and Properties Analysis of Slow-Release Microcapsules Containing Patchouli Oil

2013 ◽  
Vol 641-642 ◽  
pp. 935-938 ◽  
Author(s):  
Guang Tao Han ◽  
Zi Ming Yang ◽  
Zheng Peng ◽  
Guang Wang ◽  
Min Zhou ◽  
...  
Keyword(s):  
Ph Value ◽  
Drug Loading ◽  
Uv Spectra ◽  
Core Material ◽  
Wall Material ◽  
Complex Coacervation ◽  
Arabic Gum ◽  
Low Viscosity ◽  
Particle Size Analyzer ◽  
Infrared Spectral

Abstract: The microcapsules containing patchouli oil were prepared using a complex coacervation with chitosan and arabic gum as wall material, patchouli oil as the core material. The different factors influence on the microcapsule properties were investigated by scanning electron microscope, laser particle size analyzer, infrared spectrum and UV spectra. The best conditions for preparing patchouli oil microcapsules were confirmed as follows: the concentration of chitosan with low viscosity 0.5%, arabic gum 4%, and the ratio of wall material to core material was 2: 1. The pH value of the complex coacervation reaction was 4.5, and stirring speed was 800 r/min. The microcapsules were analyzed by Infrared spectral to confirm the patchouli oil had been successfully embedded in the microcapsules. The drug loading and encapsulation efficiency for patchouli was 20.7% and 67.2%, respectively.

Process Optimization of the Preparation of TiO2 Microcapsule Used for Photo-Catalytic Degradation with Ultrasound Irradiation

2012 ◽  
Vol 627 ◽  
pp. 770-774
Author(s):  
Xiao Mei Wang ◽  
Bao Bao Zhao ◽  
Cheng Rong Zhang
Keyword(s):  
Process Optimization ◽  
Ultrasound Irradiation ◽  
Core Material ◽  
Wall Material ◽  
Ultrasonic Power ◽  
Complex Coacervation ◽  
Photo Degradation ◽  
Reaction Solution ◽  
Ultrasonic Time ◽  
Ultrasonic Conditions

Microcapsules were prepared using the complex coacervation method with nano anatase TiO2 as the core material, gelatin/Arabia gum as the wall material, while dispersing TiO2 into the reaction solution using the ultrasonic. The prepared microcapsules can be finished into textiles such as the polypropylene nonwovens, and the microcapsules in the textiles gradually fracture and the anatase TiO2 was released, which would facilitate photo-degradation of the polypropylene nonwovens when exposed in sunlight. The microcapsules size was used as the process optimization evaluation index, and the quadratic general revolving combination design was used to conduct the experiments for obtaining the optimum ultrasonic conditions, and the other progress parameters were the same that used in our early microcapsule preparation. The obtained optimal process for ultrasound is: ultrasonic time is 17min; ultrasonic power is 74W and ultrasound temperature 60 °C.

Microencapsulation of GuaLou Seed Oil by Spray Drying

2012 ◽  
Vol 554-556 ◽  
pp. 934-937
Author(s):  
Jian Yu ◽  
Xiang Hong Li ◽  
Yong Le Liu ◽  
Chi Ling Li
Keyword(s):  
Spray Drying ◽  
Air Temperature ◽  
Seed Oil ◽  
Core Material ◽  
Wall Material ◽  
Process Conditions ◽  
Arabic Gum ◽  
Solids Content ◽  
Drying Conditions ◽  
Best Parameters

The objective of this work was to study the influence of some process conditions on the microencapsulation of Gualou seed oil by spray drying. The results showed that the best parameters of microencapsulation were as follows: the ratio of arabic gum to maltodextrin was 1:1, and that of core material to wall material was 2:3; and the total solids content was 25%. The optimum spray drying conditions were that the air temperature of inlet was 180 °C, and that of outlet was 80 °C; the homogenizing pressure was 35MPa. The maximum microencapsulation efficiency was 86±0.95%.

scholarly journals Microencapsulation of pequi pulp oil by complex coacervation

2018 ◽  
Vol 40 (2) ◽  
Author(s):  
Priscilla Narciso Justi ◽  
Eliana Janet Sanjinez-Argandoña ◽  
Maria Lígia Rodrigues Macedo
Keyword(s):  
Encapsulation Efficiency ◽  
Core Material ◽  
Asymmetric Distribution ◽  
Complex Coacervation ◽  
Arabic Gum ◽  
Influence Of Temperature ◽  
Encapsulation Process ◽  
Yield Values ◽  
Caryocar Brasiliense ◽  
Central Composite

Abstract Pequi pulp oil, Caryocar brasiliense, is rich in carotenoids, antioxidant compound easily oxidized by the presence of heat, light and oxygen. In order to improve its stability, pequi oil was microencapsulated by complex coacervation using gelatin and Arabic gum as encapsulating agents. Twenty formulations were prepared using a 23 central composite rotational design. The influence of temperature, stirring velocity and core material in the oil coacervation were evaluated, aiming to preserve carotenoids present in the oil. The best yield values and carotenoids content were obtained at the midpoint of the design (7.5g core, 15.000rpm and 50°C). Particles showed asymmetric distribution, with diameter ranging from 15 to 145 µm and the efficiency of the encapsulation process, obtained by the retention of oil in the microcapsule, ranged from 66.58 to 96.50%, thus demonstrating the encapsulation efficiency of this method.

scholarly journals Microencapsulation of Tomato (Solanum lycopersicum L.) Pomace Ethanolic Extract by Spray Drying: Optimization of Process Conditions

2019 ◽  
Vol 9 (3) ◽  
pp. 612 ◽  
Author(s):  
Luiz Corrêa-Filho ◽  
Sofia Lourenço ◽  
Daniel Duarte ◽  
Margarida Moldão-Martins ◽  
Vítor Alves
Keyword(s):  
Spray Drying ◽  
Ethanolic Extract ◽  
Core Material ◽  
Wall Material ◽  
Process Conditions ◽  
Inlet Temperature ◽  
Sem Images ◽  
Arabic Gum ◽  
Tomato Pomace ◽  
Solanum Lycopersicum L

Microencapsulation by spray-drying is a process used in the stabilization of active compounds from various natural sources, such as tomato by-products, with the purpose to be used as additives in the food industry. The aim of this work was to study the effects of wall material and spray drying conditions on physicochemical properties of microcapsules loaded with lycopene rich extract from tomato pomace. The assays were carried out with ethanolic tomato pomace extract as core material and arabic gum or inulin as wall materials. A central composite rotatable design was used to evaluate the effect of drying air inlet temperature (110–200 °C) and concentration of arabic gum (5–35 wt %) or inulin (5–25 wt %) on the antioxidant activity, encapsulation efficiency, loading capacity, and drying yield. SEM images showed that the produced particles were in the category of skin-forming structures. The most suitable conditions, within the ranges studied, to obtain lycopene loaded microparticles were a biopolymer concentration of 10 wt % for both materials and an inlet temperature of 200 and 160 °C for arabic gum and inulin, respectively. Arabic gum and inulin possessed a good performance in the encapsulation of tomato pomace extract by spray drying. It is envisaged that the capsules produced have good potential to be incorporated in foods systems with diverse chemical and physical properties.

scholarly journals Microencapsulación de extractos de higo (Ficus carica) por coacervación compleja y evaluación de su capacidad antioxidante//Microencapsulation of fig (Ficus carica) extracts by complex coacervation and evaluation of its antioxidant capacity

Biotecnia ◽  
2020 ◽  
Vol 22 (2) ◽  
pp. 70-77
Author(s):  
Laura Elena Manzanarez-Tenorio ◽  
Saúl Ruiz Cruz ◽  
Enrique Márquez-Ríos ◽  
José de Jesús Ornelas-Paz ◽  
Carmen Lizette Del-Toro-Sánchez ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Antioxidant Capacity ◽  
Ficus Carica ◽  
Wall Material ◽  
Complex Coacervation ◽  
Arabic Gum ◽  
Isolated Soy Protein ◽  
Three Stages ◽  
Pearl Formation ◽  
The Stability

Se realizó la microencapsulación por coacervación compleja de extractos de higo en tres etapas de madurez, utilizando dos complejos: Proteína de Soya Aislada con Goma Arábiga (SPI/GA) y Gelatina con Goma Arábiga (G/GA) como material de pared. La estabilidad de las cápsulas se evalúo en términos de la presencia de compuestos fenólicos, la actividad antioxidante mediante las técnicas de ABTS y bioensayo de hemólisis. El rendimiento fue mayor en el complejo de G/GA, con valores superiores al 60 %. Este complejo también logró una mejor formación de perlas de acuerdo a su morfología. Ambos complejos (SPI/GA y G/GA) mostraron estabilidad en términos de capacidad antioxidante, por lo tanto, el proceso de coacervación compleja es una técnica capaz de retener los compuestos fenólicos presentes en el higo.ABSTRACTMicroencapsulation was performed by complex coacervation of fig’s extracts in three stages of maturity, using two complexes: isolated soy protein with arabic gum (ISP/AG) and gelatin with arabic gum (G/ AG) as wall material. The stability of the capsules was evaluated in terms of the presence of phenolic compounds, the antioxidant activity using the techniques by ABTS and hemolysis bioassay. In addition, we obtained the yield percentage and morphology of the microcapsules. The yield was higher in the G/AG complex, with values greater than 60 %. This complex also has a better pearl formation according to its morphology. Both complexes (G/AG. ISP/AG and G/AG) have stability in terms of antioxidant capacity; therefore, the complex coacervation process is a technique capable to retain phenolic compounds present in fig.

Process Optimization for the Finish of PP Spunbonded Nonwovens with Photo-Catalytic Microcapsule

2014 ◽  
Vol 1048 ◽  
pp. 46-51
Author(s):  
Xiao Mei Wang ◽  
Cai Shen Chen
Keyword(s):  
Breaking Strength ◽  
Evaluation Index ◽  
Core Material ◽  
Wall Material ◽  
Orthogonal Rotation ◽  
Complex Coacervation ◽  
Experimental Scheme ◽  
The Core ◽  
Uv Lamp ◽  
Artificial Uv

Microcapsules were prepared using the complex coacervation method with nanoanatase TiO2 as the core material, gelatin/Arabia gum as the wall material. Then the obtained microcapsules were finished to the PP nonwovens to investigate the photocatalytic properties to the nonwovens. The breaking strength decrease of the finished polypropylene nonwoven after irradiated with the artificial UV lamp was the optimization evaluation index, and the four factors including finishing temperature, adhesive concentration, microcapsule concentration and finishing time were used to design the experimental scheme using the second order orthogonal rotation combination design. The data were processed with SAS software, the obtained optimal finish process is: finishing temperature is 22°C, adhesive concentration is 75g/L, microcapsule concentration is 36g/L, and finishing time 25min.

scholarly journals Preparation and performance of insect virus microcapsules

2021 ◽  
Vol 31 (1) ◽  
Author(s):  
Meng Luo ◽  
Dandan Zhu ◽  
Juntao Lin ◽  
Xinhua Zhou ◽  
Changge Zheng ◽  
...  
Keyword(s):  
Particle Size ◽  
Drug Loading ◽  
Average Particle Size ◽  
Morphological Characteristics ◽  
Core Material ◽  
Wall Material ◽  
Average Particle ◽  
Field Exposure ◽  
In The Wild ◽  
Embedding Rate

Abstract Background Biological pesticides, especially baculovirus, often lose their activity under the influence of external light, temperature, and other changes. This limited the application of them. The present study was aimed to prolong the biological activity and ensure the efficacy of a biological pesticide using microencapsulation technology. Results In this study, gelatin/carboxymethylcellulose (CMC)-Spodoptera litura nucleopolyhedrovirus microcapsules were prepared. The morphological characteristics, apparent morphology, embedding rate, virus loading, particle size, laboratory virulence, and UV resistance of the microencapsulated virus, were tested. The best conditions for preparing gelatin /CMC-S. litura nucleopolyhedrovirus microcapsules include the gelatin/CMC ratio of 9:1, wall material concentration of 1%, core material/wall ration ratio of 1:2, re-condensation pH of 4.67, and curing time of 1 h. The prepared microcapsules of S. litura nucleopolyhedrovirus exhibited a good external appearance and spherical shapes with an average particle size of 13 μm, an embedding rate of 62.53%, and a drug loading of 43.87%. The virulence test showed that the microencapsulated virus lost by 2.21 times of its initial activity than the untreated virus. After being treated with field exposure, the gelatin/CMC shell of the microcapsule can better protect the virus in the wild environment. Conclusion Microencapsulation improves the tolerance of S. litura nuclear polyhedrosis virus to ultraviolet radiation. These results will provide ideas for the research of stable and efficient baculovirus preparations and further promote the application and promotion of environmental friendly biological pesticides.

scholarly journals Microencapsulation ofβ-Carotene by Spray Drying: Effect of Wall Material Concentration and Drying Inlet Temperature

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Luiz C. Corrêa-Filho ◽  
Maria M. Lourenço ◽  
Margarida Moldão-Martins ◽  
Vítor D. Alves
Keyword(s):  
Antioxidant Activity ◽  
Spray Drying ◽  
Encapsulation Efficiency ◽  
Fruits And Vegetables ◽  
Wall Material ◽  
Inlet Temperature ◽  
Carotene Content ◽  
Arabic Gum ◽  
Air Inlet ◽  
Adverse Environmental Conditions

Carotenoids are a class of natural pigments found mainly in fruits and vegetables. Among them,β-carotene is regarded the most potent precursor of vitamin A. However, it is susceptible to oxidation upon exposure to oxygen, light, and heat, which can result in loss of colour, antioxidant activity, and vitamin activity. Thus, the objective of this work was to study the microencapsulation process ofβ-carotene by spray drying, using arabic gum as wall material, to protect it against adverse environmental conditions. This was carried out using the response surface methodology coupled to a central composite rotatable design, evaluating simultaneously the effect of drying air inlet temperature (110-200°C) and the wall material concentration (5-35%) on the drying yield, encapsulation efficiency, loading capacity, and antioxidant activity. In addition, morphology and particles size distribution were evaluated. Scanning electron microscopy images have shown that the particles were microcapsules with a smooth surface when produced at the higher drying temperatures tested, most of them having a diameter lower than 10μm. The conditions that enabled obtaining simultaneously arabic gum microparticles with higherβ-carotene content, higher encapsulation efficiency, and higher drying yield were a wall material concentration of 11.9% and a drying inlet temperature of 173°C. The systematic approach used for the study ofβ-carotene microencapsulation process by spray drying using arabic gum may be easily applied for other core and wall materials.

scholarly journals Effects of particle formation behavior on the properties of fish oil microcapsules fabricated using a micro-fluidic jet spray dryer

2020 ◽  
Vol 17 (1) ◽  
pp. 27-36
Author(s):  
Xingxing Xiong ◽  
Shengyu Zhang ◽  
Nan Fu ◽  
Hong Lei ◽  
Winston Duo Wu ◽  
...  
Keyword(s):  
Fish Oil ◽  
Oxidative Stability ◽  
Particle Formation ◽  
Core Material ◽  
Wall Material ◽  
Spray Dryer ◽  
Drying Temperature ◽  
Total Solids ◽  
Formation Behavior ◽  
Solids Content

Abstract Fish oil was encapsulated with whey protein isolate (WPI) as wall material using a Micro-Fluidic Jet Spray Dryer. The effects of core/wall material ratio, drying temperature and total solids content on the properties of microcapsules were studied. Low core/wall material ratios at 1:5 and 1:3 resulted in high encapsulation efficiency (EE) and excellent oxidative stability of microparticles during storage. Reducing the inlet temperature from 160 to 110 °C remarkably decreased EE from around 99 to 64.8%, associated with substantial increases in peroxide value during storage. The total solids content mainly altered the morphology of microcapsules, showing little influence on EE and oxidative stability. We proposed that the different drying conditions impacted on particle formation behavior during spray drying, which could be a crucial factor responsible for the differences in the quality attributes of microparticles. A low core/wall material ratio and high drying temperature facilitated the formation of a rigid protein skin at droplet surface during drying, whereas a high solids fraction in the droplets could limit possible droplet shrinkage. These factors contributed positively to the encapsulation of the lipophilic core material.

Preparation, evaluation, and in vitro release of chitosan-alginate tanshinone self-microemulsifying sustained-release microcapsules

2020 ◽  
pp. 1-9
Author(s):  
Yunhong Wang ◽  
Rong Hu ◽  
Yanlei Guo ◽  
Weihan Qin ◽  
Xiaomei Zhang ◽  
...  
Keyword(s):  
Drug Release ◽  
Sustained Release ◽  
Release Rate ◽  
Orthogonal Design ◽  
Drug Loading ◽  
In Vitro Release ◽  
Core Material ◽  
Evaluation Indexes ◽  
Vitro Release

OBJECTIVE: In this study we explore the method to prepare tanshinone self-microemulsifying sustained-release microcapsules using tanshinone self-microemulsion as the core material, and chitosan and alginate as capsule materials. METHODS: The optimal preparation technology of chitosan-alginate tanshinone self-microemulsifying sustained-release microcapsules was determined by using the orthogonal design experiment and single-factor analysis. The drug loading and entrapment rate were used as evaluation indexes to assess the quality of the drug, and the in vitro release rate was used to evaluate the drug release performance. RESULTS: The best technology of chitosan-alginate tanshinone self-microemulsifying sustained-release microcapsules is as follows: the concentration of alginate is 1.5%, the ratio of tanshinone self-microemulsion volume to alginate volume to chitosan mass is 1:1:0.5 (ml: ml: g), and the best concentration of calcium chloride is 2.0%. To prepare the microcapsules using this technology, the drug loading will be 0.046%, the entrapment rate will be 80.23%, and the 24-hour in vitro cumulative release rate will be 97.4%. CONCLUSION: The release of the microcapsules conforms to the Higuchi equation and the first-order drug release model and has a good sustained-release performance.

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