scholarly journals Clinical and Epidemiological Features of Death with COVID-19 in Karnali Province of Nepal

2021 ◽  
Vol 2 ◽  
pp. 26-32
Author(s):  
LAXMAN DATT BHATT ◽  
Rabin Khadka ◽  
Kanchan Thapa ◽  
Udaya Bahadur BC ◽  
Chetan Nidhi Wagle

Background: Coronavirus disease 2019 (COVID-19) has rapidly spread to many countries and increased mortality worldwide. Most deaths were either elderly or have underlying medical problems and even relatively young individuals have died from COVID-19. This study aimed to analyze the epidemiological and clinical characteristics of COVID-19 related deaths in Karnali Province, Nepal. Materials and Methods: We studied COVID-19 deaths from 19 May 2020 to 25 December 2020. Information from all districts of Karnali Province were included in this study. Demographic characteristics and geographic distribution map of the death toll in each district over time was analyzed. Quantum GIS(QGIS) 3.16.2 version was used to plot the deaths on maps and IBM SPSS Statistics 25 to perform statistical analysis Results: As of December 25, 2020, a total of 25 deaths were reported. Mean age of death was 52 (SD 20.99) years. Most of the deaths were distributed in age group of 50 years and above. Additionally, the male to female ratio was 5:2. A total of 56% of the deaths in Karnali were with underlying diseases and was more pronounced among males. Most of the cases were centralized in Surkhet district with highest death rate in Birendranagar municipality. Conclusion: COVID-19 poses a greater threat to the elderly people with more devastating effects, particularly in the presence of underlying diseases. The geographical distributions show that the epidemic in the Surkhet district is more serious than that in the surrounding districts. Case investigation, Contract tracing and dedicated ICU ventilator service for critical cases are essential for response of Pandemic.

2020 ◽  
Vol 8 (1) ◽  
pp. 93-99
Author(s):  
Balaji Varaprasad Mallula ◽  
Jithender Reddy Chintala ◽  
Srinadh Boppanna ◽  
S. Annapurna

Background: Stroke is the second single most common cause of death in the world causing approximately 6.7 million deaths each year. It has a greater disability impact on an individual than any other chronic disease. The aim of the study is to review the value of CTA in detection and evaluation of non-traumatic cervicocerebral vascular disease (stroke). Subjects & Methods: A prospective observational study conducted in the Department of Radiodiagnosis, Kamineni Hospitals, L.B. Nagar, Hyderabad over 60 patients during April 2016 to May 2017. Results: Out of 60 patients, 35(58.3%) patients had ischemic stroke, 25(41.6%) had hemorrhagic stroke. Overall stroke was seen mostly in the age group of 61-70 (28.3%) years, with a Male to female ratio of 3:2. Conclusion: Hypertension was the most common risk factor associated with this disease, followed by diabetes. CTA helps in accurate diagnosis, risk stratification and planning management protocols.


Author(s):  
CC Nwafor ◽  
K Obioha ◽  
TO Akhiwu

Ascites is a symptom that can originate due to diverse pathologies. A lot of investigations including ascitic fluid cytology (AFC) can be done on it to help determine its origin. The aim of this study, is to document the findings and highlight the importance of AFC in patient care in Uyo. All AFC reports and slides in the Department of Histopathology, University of Uyo were retrieved, reviewed and used for this study. The age ranged from 1.5 – 80 years with mean age, 41.79 (±17.23) years. About 71.8% of the ascitic fluid (AF) specimens were from patients between the 3rd and 6th decade. Females predominated in all age groups expect 10-19 year's group, with a male to female sex ratio of 1:2.4. Malignant cells were seen in 28.7% of all the samples, while 51.2% were negative for malignant cells. Malignant cells were seen in 4 (6.7%), 11 (18.3%) and 6 (10%) of the AFC performed due to various liver pathologies, ovarian malignancies and intra-abdominal malignancies respectively. Malignant cells were found more in females with a male to female ratio of 1: 3.6. Age group 40-49 years accounted for most of the malignant cases (26.6%). The pattern of AFC in Uyo is similar to the pattern in other parts of Nigeria


2018 ◽  
Vol 17 (06) ◽  
pp. 206-209
Author(s):  
Roshan Koul ◽  
Amna Al-Fuitaisi ◽  
Nabil Macki ◽  
Prakash Kurubarahalli Patel ◽  
Haleema Al-Balushi ◽  
...  

Objective Guillain–Barre's syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy seen in all ages but mostly in the adult population. We aim to report the incidence of GBS in children under 15 years of age in Oman, a Gulf country. Materials and Methods All children with GBS under 15 years of age were included in the study from January 2002 to December 2016. The data were compiled in Microsoft Excel format and analysis was performed using SPSS, version 17.0. Population-based age- and sex-specific rates of GBS were calculated using the estimated population for each 5-year period based on 2004, 2009, and 2014 mid-year population, respectively. Relative risk and 95% confidence intervals of GBS at different age categories were calculated using the overall incidence of GBS in those under 15 years as reference. Results The average annual incidence in those under 15 years was 3.1/100,000. Age-specific incidence was 4.0/100,000 in the age group 0 to 9 years and 4.7/100,000 in age group 0 to 4 years. Sixty percent had evidence of preceding infections, and the male to female ratio was 1.8:1. Fifty percent had cranial nerve involvement and 18% needed mechanical ventilation. Five percent had residual weakness. Intravenous immunoglobulins (IVIGs) were used in all, and 3.3% required plasmapheresis when they did not improve with IVIG. Clinical profile of the GBS was not different from the rest reported in the literature. Conclusion The incidence of GBS in Oman was 3.1/100,000 (range: 2.7–3.5 cases/100,000) in children under 15 years of age. The GBS is a smaller proportion among the total acute flaccid paralysis cases.


2020 ◽  
Vol 7 (43) ◽  
pp. 2453-2457
Author(s):  
Praveen Kumar Bairwa ◽  
Neelu Vashist ◽  
Deepti Sukheeja

BACKGROUND Malignancy is a major cause of childhood death in developed countries. In developing countries like India, paediatric tumours are rising day by day. Proper management of paediatric tumours needs epidemiological data in various geographical areas. The present study was carried out to classify and find out the histopathological profile of solid tumours of childhood and infancy in 0 - 14 years age group from 1st January 2015 to 31st December 2017. METHODS We studied histopathology reports of 173 paediatric tumours over a period of 3 years. All the biopsy cases of solid neoplasms in the age group 0 - 14 years were included. RESULTS In our study of 173 paediatric tumours, 133 (76.87 %) were benign and 40 (23.12 %) were malignant. Maximum incidence of malignant paediatric tumours was seen in the age group of 0 - 14 years [12.13 % (21 out of 173)], with male to female ratio of (1:1.3). Amongst the benign tumours, vascular tumours were most common [27.74 % (48 of 173 cases)], with highest incidence of haemangioma [68.75 % (33 of 48 cases)]. Amongst the malignant tumours, most common were bone tumours [6.35 % (11 of 173 cases)] and amongst bone tumours, Ewing’s sarcoma accounted for 63.63 % cases (7 of 11 cases). CONCLUSIONS The incidence of paediatric neoplasms in Hadoti region of Rajasthan is 0.75 % and the majority (54.33 %) of neoplasms occurred in 10 - 14 yrs. age group. KEYWORDS Histopathology, Paediatric, Non-Haematological Neoplasms


2019 ◽  
Vol 28 (1-2) ◽  
pp. 1-13
Author(s):  
Taheng Sebayang ◽  
Atan Baas Sinuhaji ◽  
Tyahaya Bangun ◽  
Manihar D. Marbun ◽  
A. H. Sutanto

The number of children attending the Pediatric Outpatient Clinic of Pirngadi Hospital, Medan, during 1982 was 15.375. Out of these, 1246 (8.1%) had gastroenteritis. Most of the patients (1046 or 83.94%) were under two years old. The male to female ratio was 1.6: I. The peak incidence for allendance was in January, April, and May. Of 1057 patients under  five years old, 383 (36.2%) also had malnutrition. The highest percentage (70. 75%) of those who had malnutrition was found in the I to 2 years age group. Of 370 patients whose Hb level was examined, 185 (50%) had anemia. The highest percentage (67.02%) was in the below 1 year group. Only 360 (28.8%) of gastroenteritis cases received oral rehydration solution. There were 23 (1.85%) cases in which diarrhea lasted longer than 7 days. The number of patients admitted to the ward was 213 (17.07%), and the highest percentage was in the above 3 years age group. The largest number of hospitalized patients was in January (43), February (21), and April (28); while the highest percentage was in April (20.40%), June (21.42%) and August (31.42%). Peak rainfall in Medan during 1982 was in October, November, and December, i.e. much 322.2 mmm,  366.4 and 382 mm, respectively.


2021 ◽  
Author(s):  
Wenli He ◽  
Danhong Xu ◽  
Jiafeng Wang ◽  
Yuze Shen ◽  
Zheng Lin ◽  
...  

Abstract BackgroundLittle is known about the gender characteristics and the Corona Virus Disease 2019(COVID-19) impact on psychiatric department outpatients in general hospitals in China. MethodsWe retrospectively collected 225,947 outpatient clinic records before and during COVID-19 pandemic from January 1, 2019 to December 31, 2020 in the psychiatric clinic of 3 general hospitals, gender composition of patients was analyzed in different five age groups and nine diagnostic categories at three levels: total patient visits, number of patients and number of first-visit patients. ResultsThe total male-to-female ratio of psychiatric outpatient records in 3 general hospitals from 2019 to 2020 was 1:1.69. Women were more common in all age groups and the male-to-female ratio of 2020 was expanded compared to that of 2019, especially in age group below 34 years old and anxiety disorders category. Most mental disorders showed higher demands for females than that for males except Mental and behavioral disorders due to psychoactive substance use with the male-to-female ratio was 1:0.05. Compared to 2019, the proportions of women were expanded especially in age group below 34 years old, and anxiety disorder and undetermined diagnosis categories were significantly increased in 2020. ConclusionsThe demand for female psychiatric outpatient services is obviously higher than that for males. It is necessary to pay more attention to explore targeted mechanism or psychosocial service strategy for female patients with mental disorders. Trial registration: ChiCTR2100044894, March 31,2021 retrospectively registered.


Author(s):  
Samia O. Massaad ◽  
Mohammed Ahmed A. Ahmed ◽  
Afra M. Mustafa ◽  
Sami Eldirdiri Elgaili Salah ◽  
Saeed M. Omar ◽  
...  

<p><strong>Background: </strong>Acquired heart diseases (AHD) are heterogeneous diseases including rheumatic heart disease (RHD) and other affecting the heart and blood vessels after birth but usually appear clinically after 5 years of age. AHD considered as major cause of   morbidity and mortality. The present study was designed to document the spectrum, the affected age and clinical characteristics of AHDs in children of Gadarif state, eastern Sudan.</p><p><strong>Methods</strong>: This was a descriptive cross section study conducted in Gadarif pediatrics teaching hospital in period from June to Dec 2019.</p><p><strong>Results: </strong>A total of 46 children from Gadarif pediatrics teaching hospital with confirmed AHD were enrolled in this study. The females were 27 (58.7%), with a male-to-female ratio of 1.4:1. The mean age was 10.6±3.9 years (age’s ≤16 years old); the most common affected age group was 10-14 years accounted 18 (39.1) cases. RHD was the commonest AHD found in 38 (82.6%) patients, the commonest valvular lesion was mitral regurgitation 31 (73.9%).</p><p><strong>Conclusions: </strong>RHD was the most common AHD in the children in the present study, there is need to improve the scope of intervention facilities in the Sudan particularly in rural areas to prevent the growing and spread of these diseases.</p>


2014 ◽  
Vol 21 (06) ◽  
pp. 1204-1208
Author(s):  
Faisal Shahab ◽  
Irfan Murtaza Shahwani ◽  
Shuaib Ansari ◽  
Syed Zulfiquar Ali Shah

Objectives: To identify the frequency of risk factors in hemorrhagic stroke at Liaquat university of medical and health sciences. Patient and methods: This Descriptive case series study of six months was carried out in the department of medicine, Liaquat University of Medical and Health Sciences. Patients aged 20-70 years of age with hemorrhagic stroke on CT were enrolled in the study after taking consent from caretaker of patients. Detailed history focusing on hypertension, diabetes and smoking and their duration was taken. Blood pressure was recorded and fundoscopy was done to find out diabetic or hypertensive retinopathy. Thorough neurological examination and fasting / random blood glucose level was evaluated while the data was done was analyzed using SPSS version 16. Results: A total of 100 patients were included in the study during study period. 61% of patients were in > 50 years of age group with mean age of 53.4±11 years. A total of 66 (66%) were male; with male to female ratio was 2:1. Hypertension was present in 63% of cases, Diabetes was found in 24% cases and 44 patients were cigarette smokers. Conclusions: It was concluded that high blood pressure, diabetes mellitus and smoking are associated with hemorrhagic stroke.


Author(s):  
Bibhu P. Behera ◽  
D. N. Maharana ◽  
Partha S. Mohanty

Background: Stroke is one of the leading causes of morbidity and mortality in India. The objective was to study the clinical profile, risk factors, neurological characters, pattern of brain stroke, areas of brain affected as per CT scan findings in patients with stroke.Methods: This observational study was carried out from June 2018 to Jan 2019 of all new patients admitted with stroke in Pandit Raghunath Murmu Medical College and Hospital, Baripada, Mayurbhanj, Odisha, India.Results: The incidence of stroke is maximum in 46-60 years of age group. The average age+SD was 59.3+13.5 in our study. 274 (46.52%) patients had ischemic stroke and 315 (53.48%) patients had hemorrhagic stroke. The male to female ratio was 1.46:1. Anterior circulation (86.42%) was the most common territory involved in the brain. The most common risk factor was hypertension with 77.76% followed by dyslipidemia (53.99%). The most common clinical presentation was hemiplegia (85.23%).Conclusions: The incidence of stroke is maximum in 46-60 years of age group. The average age+SD was 59.3+13.5 in our study. 274 (46.52%) patients had ischemic stroke and 315 (53.48%) patients had hemorrhagic stroke. The male to female ratio was 1.46:1. Anterior circulation (86.42%) was the most common territory involved in the brain. The most common risk factor was hypertension with 77.76% followed by dyslipidemia (53.99%). The most common clinical presentation was hemiplegia (85.23%). 


Author(s):  
Benazeer Mansuri ◽  
Komal P. Thekdi

Background: Megaloblastic anemias are hematologic disorders in which abnormal DNA synthesis causes blood and bone marrow disorders. The cause of thrombocytopenia in megaloblastic anemia has been postulated as hypoproduction in some studies, whereas ineffective thrombopoeisis has been proposed in other. Objective was to study spectrum of clinic-hematological features in megaloblastic anemia and comparative bone marrow aspiration study of thrombocytopenia secondary to megaloblastic anemia, hypoproduction and hyper-destruction. This study was done to understand the various megakaryocytic alterations in hematological disorders presenting with thrombocytopenia due to different mechanisms.Methods: Total 85 cases of thrombocytopenia included in the study. Bone marrow finding in 33 cases of thrombocytopenia of megaloblastic etiology were compared with 34 cases of marrow proven hypo productive thrombocytopenia (aplastic anemia, acute leukemia) and 19 cases of hyper destructive thrombocytopenia (immune thrombocytopenia).Results: Most common age group presenting megaloblastic anemia is 11-20 year, with male to female ratio is1.2:1, most common complaint were generalized weakness and fever. In megaloblastic anemia 24.33%, 60% and 15.67% of the cases shows increase, decrease and normal megakaryocytes respectively. Dysplastic megakaryocytes were observed in 24.3%, 27% and 20.5% of the cases of megaloblastic anemia, acute leukaemia and immune thrombocytopenic purpura respectively.Conclusions: Both hypoproduction and ineffective thrombopoiesis are the underlying path mechanisms in megaloblastic thrombocytopenia as evidenced by the marrow findings. We hereby infer that megaloblastic thrombocytopenia is to be included as a separate category apart from hypo proliferative and hyper destructive groups. The presence of dysplastic megakaryocyte should not prompt an interpretation


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