scholarly journals RANDOMISED CONTROLLED CLINICAL STUDY OF KUSHTADI YONI VARTI ON CERVICAL EROSION

2021 ◽  
Vol p6 (1) ◽  
pp. 3157-3162
Author(s):  
Sindhu Umesh ◽  
Jayasudha G. C ◽  
Ramesh M
Keyword(s):  
Vaginal Discharge ◽  
Pap Smear ◽  
Local Treatment ◽  
Group A ◽  
Group B ◽  
Randomised Controlled ◽  
Controlled Clinical Study ◽  
Efficacy Of Treatment ◽  
Better Than

Cervical Erosion may present with symptoms like vaginal discharge or serious problems of female infertility and thus gains importance in the gynaecological practice1. This entity is correlated with GarbhashayaMukhaGata Vrana (GGV), of Vatakaphaja variety. In the present study, Kushtadi YoniVarti (KYV) 2 is proposed as a local treatment for Cervical Erosion. The present study has two groups: Group A:30 patients, were treated with Kush- tadi Yoni Varti, followed by Sukhoshna Jala Prakshalana for 7 consecutive days. Group B:30 patients were ad- vised with Pathya and apathy for 7 days. The Follow up for both groups were on 14th Day and 21st Day. The re- sults were analysed statistically with paired and unpaired t-test. On comparing the two groups, it was found that the efficacy of treatment in Group A was better than the efficacy of treatment in Group B with reference to amount and odour of discharge, appearance and degree of erosion. Keywords: Cervical Erosion, Kushtadi Yoni Varti, GarbhashayaMukhaVrana, PAP Smear.

A Randomised, Controlled Clinical Study on Total Hip Arthroplasty Using 4 Different Bearings: Results after 10 Years

2016 ◽  
Vol 27 (1) ◽  
pp. 96-103
Author(s):  
Arne Borgwardt ◽  
Bo Zerahn ◽  
Sandra D. Fabricius ◽  
Tine H. Bertelsen ◽  
Henrik Daugaard ◽  
...  
Keyword(s):  
Clinical Study ◽  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Total Hip ◽  
Metal On Metal ◽  
Group A ◽  
Group B ◽  
Randomised Controlled ◽  
Group D ◽  
Controlled Clinical Study

Purpose To compare 4 different bearings in total hip arthroplasty (THA) in a randomised controlled clinical study on clinical performance. Methods 393 patients with osteoarthritis of the hip or avascular necrosis were included and allocated to 1 of the head-and-cup couples zirconia-on-polyethylene (group A), metal-on-metal (group B), zirconia-on-polyethylene with the liner moulded into the shell (group C), or alumina-on-alumina (group D). In the individual case the surgeon could choose other implants if indicated. Results 299 patients were operated with the allocated prosthesis. The estimated cumulated prosthesis survival percentages and 95% confidence interval after 10 years were: group A 84.6 (75.8-93.4); group B 95.0 (89.5-100); group C 93.2 (86.7-99.7); group D 66.1 (54.5-77.7). The patients' physical function was significantly improved and remained equally good in all 4 groups, however slightly declining with ageing. The luxation rate was initially high, and equal between the groups, but was reduced by improving the surgical procedure introducing capsule repair by reinsertion of the short external hip rotators. Conclusions The metal-on-metal or zirconia-on-polyethylene prostheses had high 10-year survival percentages. The longevity of these bearing couples by themselves was not related to the combination of materials. The zirconia-on-polyethylene prosthesis with the liner mounted peroperatively possibly exhibited cases of backside wear which the corresponding bearing couple with moulded polyethylene (Asian) did not. The alumina-on-alumina bearing performed poorly - it was redesigned after our study initiation and later withdrawn from the market.

Cancer-Related Venous Thrombosis: Residual Vein Thrombosis Improves Screening for Occult Cancer.

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 699-699
Author(s):  
Sergio Siragusa ◽  
Alessandra Malato ◽  
Fabio Fulfaro ◽  
Domenica Caramazza ◽  
Lucio Lo Coco ◽  
...  
Keyword(s):  
Early Detection ◽  
Pap Smear ◽  
First Episode ◽  
Vein Thrombosis ◽  
Occult Cancer ◽  
Group A ◽  
Group B ◽  
Mean Time ◽  
Related Mortality

Abstract Background. Clinical advantages of extensive screening for occult cancer in patients with idiopathic Deep Vein Thrombosis (DVT) is still debated since this approach improves early detection of cancer but not cancer-related mortality. Recently, we have demonstrated that patients with Residual Vein Thrombosis (RVT), 3 months after DVT, have a high risk for cancer in the subsequent 2 years (Siragusa S et al. Blood2005;106(11):OC262). At the present it is unknown whether RVT assessment may be used to select patients, with idiopathic DVT, who require screening for occult cancer. Objective of the study. We conducted a prospective study evaluating whether a RVT-based screening for cancer is sensitive and influences cancer-related mortality. Study design. Prospective with two cohorts of DVT patients: the first cohort was monitored for clinical overt cancer only (Group A), while the second (Group B) received complete screening for occult neoplasm and subsequent surveillance. Materials and methods. Consecutive patients with a first episode of DVT who presented RVT after 3 month of anticoagulation and without signs and/or symptoms for overt cancer. Screening for occult cancer was based on: ultrasound and/or CT scan of the abdomen and pelvis, gastroscopy, colonoscopy or sigmoidoscopy, hemoccult, sputum cytology and tumor markers. These tests were extended with mammography and Pap smear for women and ultrasound of the prostate and total specific prostatic antigen (PSA) for men. All investigations had to be completed within four-weeks from the assessment of RVT. All patients were followed-up for at least 2 years. Incidence and cancer-related mortality was compared between the two groups by survival curves (Kaplan-Mayer) and related Breslow test for statistics. Results. Over a period of 6 years, 345 patients were included in the analysis: first cohort included 213 patients (Group A), second cohort 132 (Group B). Clinical characteristics between groups were homogenous. During the follow-up, 8.4% of patients developed overt cancer in group A; in group B, 8.3% of patients had diagnosed cancer at the moment of extensive screening while one new case (0.7%) occurred during the follow-up (Table). The sensitivity of this approach was 91.6% (95% confidence intervals 74.7–108.5). Cancer-related mortality was 6.5% in group A and 3.0% in group B (p< 0.001) (Figure). Conclusions. Our study demonstrates that RVT-based screening for occult cancer improves early detection as well as cancer-related mortality. Cancer events during surveillance Characteristic Group A (n= 213) Group B (N= 132) *4+0.5 months. **At least 24 months Cancer, No (%) at screening time* - - **10 (8.3) Cancer, No (%) during clinical surveillance** 18 (8.4) 1 (0.7) Density incidence (cases x 1000 p/y) 41.9 40.3 Mean time cancer diagnosis (months ±SD) 6.9 (1.3) 3.6 (0.7) Cancer-related mortality, No (%) 14 (6.5) 4 (3.0) Cancer-related mortality, mean time (months ±SD) 19 (3.4) 18 (2.8) Figure: Cancer - related mortality Figure: Cancer - related mortality

A Comparison of Acupuncture with Advice and Exercises on the Symptomatic Treatment of Osteoarthritis of the Hip – a Randomised Controlled Trial

2001 ◽  
Vol 19 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Roisin Haslam
Keyword(s):  
Controlled Trial ◽  
Randomised Trial ◽  
Symptomatic Treatment ◽  
Post Treatment ◽  
Control Group ◽  
Group A ◽  
Pre Treatment ◽  
Group B ◽  
Randomised Controlled

Acupuncture is becoming a common technique within the physiotherapy profession as a treatment modality for pain relief; however, few randomised controlled trials have been undertaken to assess the effectiveness of acupuncture, particularly in the treatment of osteoarthritis (OA) of the hip. Therefore, a randomised trial to compare the effectiveness of acupuncture with advice and exercises on the symptomatic treatment of OA of the hip was carried out. Thirty-two patients awaiting a total hip arthroplasty were randomly allocated to either the experimental group, (A), to have six sessions of acupuncture each lasting up to 25 minutes, or the control group, (B), to be given advice and exercises for their hip over a six week period. Group A consisted of three men and 13 women, and group B consisted of four men and eight women. The average age in group A was 66 years and in group B it was 68 years. Patients were assessed for pain and functional ability, using a modified version of the WOMAC questionnaire, pre-treatment, immediately post-treatment and at eight weeks post-treatment. The pre-treatment WOMAC scores in the two groups were similar (p=0.85). There was a significant improvement in group A (decrease in WOMAC score) immediately post-treatment (p=0.002) and this was maintained at the eight-week follow-up (p=0.03). There were no significant changes in group B. When the changes in WOMAC scores were compared between groups, a significantly greater improvement was found between pre-treatment and immediately post-treatment in group A, compared with group B (p=0.02). The changes between pre-treatment and the eight-week follow-up also showed a significant improvement in group A compared with group B (p=0.03). In conclusion, this trial supports the hypothesis that acupuncture is more effective than advice and exercises in the symptomatic treatment of OA of the hip.

scholarly journals Comparative study of oral ivermectin, topical permethrin and benzyl benzoate in the treatment of scabies

2019 ◽  
Vol 7 (12) ◽  
pp. 4743
Author(s):  
G. Chitti Babu ◽  
Kavita Dhar Bagati ◽  
Praveen Agarwal ◽  
Jyostna Sharma
Keyword(s):  
Good Alternative ◽  
Benzyl Benzoate ◽  
Effective Treatment Option ◽  
Treatment Groups ◽  
Number Of Patients ◽  
Group A ◽  
Group B ◽  
Clinical Grading ◽  
Better Than

Background: Efficacy of these modalities as shown by various investigations are inconsistent and ambiguous. Thus, evidence based effective treatment option is warranted. Aim of the study was to compare the efficacy of oral ivermectin, topical permethrin and benzyl benzoate in the treatment of uncomplicated scabies.Methods: Patients with confirmed diagnosis of scabies were included in this study. One hundred and ninety-five subjects were included in this investigation as per inclusion and exclusion criteria laid down. Equal numbers of patients were randomly allocated to one of the three treatment groups. Efficacy of three groups [oral ivermectin (Group A), topical permethrin (Group B) and benzyl benzoate (Group C)] of drugs was compared in terms of improvement in clinical grading of disease (%) and improvement in clinical grading of pruritus (%) during follow up visits.Results: Those subjects receiving topical permethrin, at 1st follow up 56.9% showed cure rate which increased to 89.2% at 2nd follow up with respect to clinical improvement in pruritus. Maximum relief in severity of pruritus at the end of 6th week was reported by 58(89.2%) patients receiving group B treatment modality followed by 52 patients (80%) in arm A. Regarding efficacy of three treatment groups in terms of improvement in severity of lesion at the end of 6 weeks, maximum number of patients 57(87.7%), receiving group B treatment reported improvement which is better than other two treatment groups.Conclusions: maximum number of patients receiving topical Permethrin treatment reported improvement better than other Oral Ivermectin therapy and topical benzyl benzoate. Oral ivermectin may serve a good alternative for managing scabies under certain conditions like poor compliance to topical scabicides.

scholarly journals A CLINICAL STUDY TO EVALUATE THE EFFECT OF GUDUCHYADI SYRUP IN ENHANCEMENT OF MEDHA IN SCHOOL GOING CHILDREN

2020 ◽  
Vol 8 (9) ◽  
pp. 4368-4374
Author(s):  
Navya. N. P ◽  
Sharada. M. K ◽  
Jithesh Chowta
Keyword(s):  
Clinical Study ◽  
Modern Medicine ◽  
School Factors ◽  
Sugar Syrup ◽  
Scholastic Backwardness ◽  
Group A ◽  
Group B ◽  
Controlled Clinical Study ◽  
Intellectual Power

Academic underachievement of children is a big concern among parents and teachers in present day competitive society. It is reported that around 20% of school children have scholastic backwardness include physical illness, below average Intelligence, Learning Disabilities, Attention Deficit Hyperactive Disorder, Psychiatric Disorder, family and school factors. Intelligence is usually said to involve mental capabilities such as the ability to reason, plan, solve problems, think abstractly, comprehend ideas and language, and learn. In spite of advancement in modern medicine, its success is very limited in context with the enhancement of Intellectual power and memory. Objectives: 1) To select subject with IQ ranging from 70 – 89 and study in detail about the factors influencing the Intelligence. 2) To evaluate the effect of Guduchyadi Syrup in the enhancement of Medha in school going children. Materials and Methods: An interventional Randomized Placebo Controlled Clinical study was conducted, in which 30 subjects were assigned in both Group A and Group B and given with Guduchyadi syrup and Sugar syrup respectively, with a dose of 5ml thrice a day after food for duration of 3 months. Follow up was done on 30th day after completion of the treatment. Interpretation and Result: Both the groups showed significant result in Subjective and Objective parameters. Conclusion: Both Guduchyadi syrup and Sugar syrup are having significant effect on Medha. The effect is considered to be consistent or improved even after follow up. But the change was less for the group given with Sugar syrup compared to the effect of Guduchyadi syrup.

scholarly journals Role of bicipital tenotomy in adhesive capsulitis

2020 ◽  
Author(s):  
Mohamed Aly
Keyword(s):  
Frozen Shoulder ◽  
Capsular Release ◽  
Biceps Tenotomy ◽  
Arthroscopic Capsular Release ◽  
Group A ◽  
The Mean ◽  
Long Head ◽  
Group B ◽  
Better Than

Purpose: To compare the results of arthroscopic capsular release of frozen shoulder with the tenotomy of the long head of biceps tendon versus capsular release without long head of biceps tenotomy. Methods: This is a prospective study that will include forty patients with resistant frozen shoulder presenting to El- Hadra University Hospital, Alexandria, Egypt. Arthroscopic release will be performed on twenty patients with biceps tenotomy (group A), while the other twenty patients will undergo arthroscopic release without biceps tenotomy (group B). Patients were evaluated preoperatively, at 2 week and 6 weeks postoperatively as regard Constant and Murley score. Results: In group (A), at the end of the follow up period, the mean score was (84.55 ± 19.32) ranging from 68.0 – 164.0 according to the Constant and Murly shoulder score. (table 5) . In group (B), at the end of the follow up period, the mean score was (79.55 ± 6.85) ranging from 68.0 – 94.0 according to the Constant and Murly shoulder score. . The difference between the means of postoperative total score in both groups was statistically insignificant (p = 0.718). Conclusion: Arthroscopic capsular release is an effective and safe method for treatment of refractory cases of frozen shoulder in which other treatment methods failed. Arthroscopic capsular release, achieves dramatic pain and motion improvement immediately postoperative, allowing very early postoperative rehabilitation. Circumferential capsular release is mandatory to achieve considerable range of shoulder motion in all directions. There are no significant differences between arthroscopic capsular release with biceps tenotomy and without biceps tenotomy regarding to final Constant and Murley score. Internal rotation is the slowest and most difficult motion to recover while gains in forward elevation are achieved the fastest.The improvement in range of external rotation is better than the improvement in the internal rotation. Diabetes mellitus is a bad prognostic risk factor, and the improvement in the range of motion in non-diabetic patients is better than the improvement in diabetic

Tripod allograft in reconstruction of incudal lesions

1994 ◽  
Vol 108 (3) ◽  
pp. 206-211 ◽  
Author(s):  
Michal Luntz ◽  
Talia Mark Bentacur ◽  
Jacob Sadé
Keyword(s):  
Pathological Condition ◽  
Long Term Results ◽  
Indication For Surgery ◽  
Retraction Pocket ◽  
Graft Extrusion ◽  
Group A ◽  
Group B ◽  
Better Than

AbstractLong-term results of allograft ossiculoplasty with erosion of the long process of the incus in 44 patients are described. The pyramidal-shaped allograft leans on the stapes, the remaining part of the incus and the side of the malleus - forming a ‘tripod’ shape or construction.The study includes two groups of patients: group A (34 patients) in whom the pre-operative three-frequency average air-bone gap was 20 dB or more and group B (10 patients), in whom the pre-operative air-bone gap was less than 20 dB. In the latter group the indication for surgery was not their hearing loss, but a different pathological condition (infected retraction pocket, a cholesteatoma, etc.) which necessitated surgical disconnection of the chain during the operation.The average period of follow-up 46 months for group A and 24.9 months for group B. In group A, the preoperative average air-bone gap was 33 dB. Following surgery, the air-bone gap was 20 dB or less in 27 ears (79 per cent), and 10 dB or less in 18 of them (53 per cent). In group B, pre-operatively, the average air-bone gap was 11 dB. Following surgery, the air-bone gap was either better than before the operation or did not increase by more than 5 dB in eight patients (80 per cent).Comparison of the audiometric results of 20 patients after mean follow-up times of 23.8 months and 64.9 months shows that no deterioration of hearing occurred in the intervening period. Graft extrusion was not observed in any of the operated ears.

scholarly journals Single versus Double Burr Holes for Treating Chronic Subdural Hematoma

2020 ◽  
Vol 9 (2) ◽  
pp. 99-104
Author(s):  
Uzzal Kumer Sadhu Khan ◽  
Asit Chandra Sarker ◽  
Md Mahamudul Haq Morshed ◽  
Md Motasimul Hasan ◽  
Saiful Hoque ◽  
...  
Keyword(s):  
Subdural Hematoma ◽  
Chronic Subdural Hematoma ◽  
Cerebral Atrophy ◽  
The Elderly ◽  
Burr Hole ◽  
Group A ◽  
Group B ◽  
Burr Holes ◽  
Better Than

A subdural hematoma is a collection of blood below the inner layer of the dura but external to the bran and arachnoid membrane.Chronic subdural hematoma is commonly associated with cerebral atrophy, occur in the elderly after apparently insignificant head trauma. The incidence of Chronic subdural hematoma increases with age and after 70 years of age. Surgical evacuation of hematoma is indicated in patients who are clinically deteriorate or do not improve. Surgery can bring a rapid clinical improvement with a favorable outcome in over 80% of patient. Methods: This study was a prospective intervention study. Results: It was observed that 29 (96.6%) patients were alive in group A and 27 (90.0%) patients alive in group B in GOS scoring on the 7th POD. The alive patients were again divided into 4 sub groups, as shown in the table. Among total 60 patients, in Group A 1(3.4%) died and 3 (10.0%) died in Group B. After 3 months follow up, it was observed that 29 (96.6%) patients were alive in group A and 27 (90.0%) patients alive in group B. The alive patients were again divided into 4 sub groups, as shown in the table. Persistent vegetative and severe disability was not improved in Group B. Conclusion: In my study it was observed that the surgical outcome in single burr hole craniotomy is better than double burr hole craniotomy for treating of chronic subdural hematoma. Bang. J Neurosurgery 2020; 9(2): 99-104

A Comparative Study on the effect of Padabhyanga with Tila Taila and Nimba Taila in management of Vipadika w.s.r. to Padasputana

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Dr. Asha Karki ◽  
Dr.Mallikarjun S. Yalagond ◽  
Dr.Venkatesh Illal
Keyword(s):  
Food Habits ◽  
Complete Relief ◽  
Chi Square ◽  
Medical College ◽  
Comparative Clinical Study ◽  
Chi Square Test ◽  
Group A ◽  
Group B ◽  
Better Than

Background: Vipadika affects irrespective of age, sex and socioeconomic status. The causes may be excessive/barefoot walking, contact with dust, detergents and improper food habits. Here control over Vatadosha is important which can be achieved through Padabhyanga. Materials and Methods: It was a comparative clinical study of 30 patients, who were selected by random sampling from the OPD of S.M.V.V.S, R.K.M Ayurveda Medical College, Vijayapura, and categorized into 2 groups as 'A' and 'B', each consisting of 15 patients and were advised Tila Taila and Nimba Taila Padabhyanga for 30 days respectively. Follow up was advised on 45th day of treatment. Severities of the symptoms were assessed before, after treatment and after follow up. Results: In group-A 20% of patients showed complete relief and in group-B 0% have showed complete relief. Conclusion: Tila Taila is having Sara, Sukshma Guna and pacifies Vatakapha Dosha. Nimba Taila is Kushtagna, Krimigna. Both Tailas help in reducing Rukshata and Sputana. Vipadika can be correlated with cracked heels. The results were assessed statistically by Pooled chi square test. It was concluded that group-A patients were significantly better than group-B after follow up. Hence Tila Taila Padabhyanga is beneficial in Vipadika.

scholarly journals Comparative Study of Evaluation of Efficacy and Safety of Combination of Erythromycin and Benzyl Peroxide with Benzyl Peroxide alone in the Treatment of Acne Vulgaris

2017 ◽  
Vol 35 (4) ◽  
pp. 174-178
Author(s):  
Monira Yeasmin ◽  
AZM Maidul Islam
Keyword(s):  
Acne Vulgaris ◽  
Topical Therapy ◽  
Treatment Modalities ◽  
Base Line ◽  
Efficacy And Safety ◽  
Lesion Count ◽  
Group A ◽  
Group B ◽  
Better Than

Objective: Acne vulgaris is the disease of the teenagers as 90% of them being affected. So many treatment modalities are there - systemic , topical and physical . Among them topical therapy is the main stay of treatment. Our study was to determine the efficacy and safety of combination of erythromycin/benzyl peroxide compared with benzyl peroxide alone in the treatment of mild to moderate acne.Method: Patients attended in a Charity Foundation were enrolled for the study after fulfilling the criteria. Among total 50 patients 25 were selected for group A and another 25 for group B.. Group A were treated with 3% erythromycin and 5% Benzyl peroxide combination and GroupB with 5% Benzyl peroxide only. Total acne lesions were counted at base line and after 4 , 8 and 12 weeks of follow up. Reduction of total no of lesions were seen and analyzed.Result: At baseline mean of total acne score was 33.60 ± 5.98 and 33.53 ± 5.68 in group A and B (p=0.965). After 12 week it was 2.27 ± 1.08 and 6.27 ± 1.57 respectively in group A and B (p=0.001). Percent reduction of acne severity from base line to final follow up was 93.24 ± 3.11 in group A and 81.17 ± 4.22 in group B (p=0.001). So we can see better reduction of lesion count in Group A than Group B.Conclusion: We conclude that Group A is safer and more effective than that of Group B. So the combination of Benzyl peroxide and erythromycin is better than Benzyl peroxide alone.J Bangladesh Coll Phys Surg 2017; 35(4): 174-178

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