scholarly journals STANDARDIZATION OF NASYA DOSE BY BINDU PRAMANA WITH KARPASASTYADI TAILA

2021 ◽  
Vol 9 (6) ◽  
pp. 1200-1204
Author(s):  
Sreeja. V. S ◽  
Vikram Kumar
Keyword(s):  
Side Effects ◽  
Study Group ◽  
Classical Concept ◽  
Subject Analysis ◽  
Optimum Result ◽  
Medical College

Panchakarma therapy has a very important role in maintaining health of a person and eradication of diseases. The success with Panchakarma therapies can be achieved not only through correct assessment of the patient and the medicines used but also the dose of the medicine. Dose for this therapy is very specific and is explained in the classics on the basis of Bindu Pramana. Dose is a very important factor in any of the Panchakarma procedures to get optimum result of the therapy. Change in dose can change the result and further, it can lead to side effects or no effects. However, standardization of this dose had not been made yet. This paper deals with classical concept of Bindu Pramana, preparation, and standardization of Karpasastyadi Taila in Bindu Pramana Matra. The objective is to standardize the process of measurement of Bindu Pramana Matra of Karpasastyadi Taila. Healthy 60 individuals consisting of staffs and students of Alvas Ayurveda Medical College of either gender aged between 20 years to 60 years were selected and purposively assigned into study group. Results were observed and tabulation of data with a statistical commentary based on percentages of different observations was made. Study shows variation in quantity of Madhyama Bindu Pramana Matra and differs from patient to patient. Bindu Pramana varies from subject to subject. Analysis of the results showed that Bindu is not equivalent to drop. Keywords: Panchakarma; Nasya Karma; Karpasastyadi Taila; Bindu Pramana

scholarly journals Chronic vaginal discharge; presentation and management among women of underdeveloped areas.

2020 ◽  
Vol 27 (05) ◽  
pp. 910-914
Author(s):  
Sheeba Rehman ◽  
Shahnilah Zafar ◽  
Sara Gulbaz
Keyword(s):  
Side Effects ◽  
Vaginal Discharge ◽  
Lower Abdominal Pain ◽  
Cross Sectional Study ◽  
High Rate ◽  
Study Group ◽  
Cross Sectional ◽  
Medical College ◽  
Underdeveloped Areas ◽  
Microsoft Office

Objectives: To determine various presentations of patients with chronic vaginal discharge belonging to underdeveloped areas and its response to management. Study Design: Cross sectional study. Setting: Rai Medical College, Doctors Trust Teaching Hospital Sargoodha. Period: 07 months from July to December 2018. Material & Methods: This study was conducted in Obstetric and Gynaecology unit of study institution. Total 150 cases were included in this study belonging to underdeveloped areas around Sargodha city presenting with vaginal discharge for more than 6 months duration. These cases were reported in outpatient door of gynae unit. Ages of these cases were 18-45 years. Patients with pregnancy, abnormal vagina or cervix and having growth of cervix were not included in this study. Permission was obtained from all cases for including them in this study. All data collected was analyzed in Microsoft office and version 2018 and expressed via tables and graphs. Results: Total 160 cases were included in this study presenting with the history of vaginal discharge with more than 6 months history. Their age range was 18-45 years with mean age of 35 years. Presenting complaints in study group were vaginal discharge in all (100%) cases, lower back pain in 53(33%), lower abdominal pain in 41(25.6%), itching in 38(23.8%), dysuria reported in 25(15.6%), dysparunia in 21(13%) cases and post coital bleeding reported in 18(11.3%) cases. Mean parity of cases in study group was 3±1. Vaginal infection was resolved in 70% cases after treatment with first line antibiotics and recovery rate increased up to 90% after treatment with 2nd line antibiotics. Various side effects of drugs were reported in study group. Most common side effects were anorexia in 9.4% cases, nausea in 7% and abdominal discomfort was reported in 5.6% cases. Conclusion: There is very high rate of sexual transmitted diseases among women living in peripheral under developed areas due to lack of proper awareness and high illiteracy rate among women. WHO recommended Symptomatic management is very effective in these cases.

scholarly journals Postpartum intrauterine contraceptive device: evaluation of acceptance and complications

2019 ◽  
Vol 8 (8) ◽  
pp. 3219
Author(s):  
Sindhu S. Gaur ◽  
Suman Mendiratta
Keyword(s):  
Retrospective Study ◽  
Side Effects ◽  
Tertiary Care ◽  
Acceptance Rate ◽  
Intrauterine Contraceptive Device ◽  
Study Group ◽  
Contraceptive Device ◽  
Medical College ◽  
Intrauterine Contraceptive

Background: Postpartum intrauterine contraceptive device is inserted within 10 minutes to 48 hours of expulsion of placenta. The objective of the study was to determine acceptability, safety and complications of PPIUCD in tertiary care center.Methods: This is a retrospective study conducted at Zenana Hospital, SMS Medical College, Jaipur over a period of 1 year from April 2018 to March 2019. Women were followed after 6 weeks and their complaints and various parameters were analyzed.Results: 5653 women were inserted PPIUCD during 1 year period. Acceptance rate was 29.26% and higher in multipara (54.30%) and between 18 to 25 years of age (50.29%). The main complaints at follow-up were pain and bleeding which were dealt mainly by reassurance. Main cause of removal was bleeding, pain and family pressure.Conclusions: The acceptance was high in this study group. PPIUCD is safe, effective and acceptable with negligible side effects. PPIUCD has abundant scope in India where accessibility for contraception is lower during interval period and women do not come for follow-up after delivery.

Side Effects of Chemotherapy and Cancer Treatment in Tertiary Care Teaching Hospital

2016 ◽  
Vol 2 (1) ◽  
pp. 62-78
Author(s):  
. Hemraj ◽  
Raj Kumar ◽  
Sourabh Kosey ◽  
Amit Sharma ◽  
Nalini Negi
Keyword(s):  
Side Effects ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Informational Needs ◽  
Cross Sectional ◽  
Clinical Pharmacists ◽  
Medical College ◽  
Related Information ◽  
The Common ◽  
Chemotherapy Patients

To determine the most common physical side effects experienced by local chemotherapy patients. Their perceptions of these side effects and informational needs from clinical pharmacists were also evaluated. This was a single center, observational cross-sectional study conducted at department of General Surgery, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab. A face to face interview was conducted. Information collected included chemotherapy related side effects after last chemotherapy experience, the most worrisome side effects, overlooked by healthcare professionals and the preferred method, amount and source of receiving related information. In this study, hundred patients were enrolled out of them 48 were male and 52 were female. When differential calculations was done, common side effects or adverse effects of chemotherapy in the patients of breast, lung cancer, Ovarian Cancer, Colon cancer, Prostate cancer, Lymphoma Cancer, Cervix cancer where there is much irregular medicine intake 57.4% may be due to common problem of joint pain reported by all the patients under study, with the consecutive problem of nausea and vomiting. The high prevalence of chemotherapy related side effects among local patients is a major concern and findings of their perceptions and informational needs may serve as a valuable guide for clinical pharmacists and physicians to help in side effect management. This study shows the common problems reported by the patients when they are suffering from cancer condition, according to their incidence perceptions as experienced by the patient, this will allow the physician and clinical pharmacist to effectively counsel and manage the common symptoms as reported prior to its occurrence in the patient, so that withdrawal can be checked.

A Study on Clinical Evaluation and Management Modalities in Benign Breast Diseases

2021 ◽  
Vol 8 (03) ◽  
pp. 168-171
Author(s):  
Ajay Chanakya V ◽  
Sreekanth Kotagiri ◽  
Gogineni Tarun Chowdary ◽  
Sriram K.V.V.S.D. ◽  
Ch. Vasu Reddy ◽  
...  
Keyword(s):  
Surgical Oncology ◽  
Needle Aspiration ◽  
Breast Diseases ◽  
Study Group ◽  
Psychological Burden ◽  
Diagnosis And Management ◽  
Medical College ◽  
Benign Breast Diseases ◽  
Needle Aspiration Cytology ◽  
A Prospective Study

BACKGROUND Benign breast diseases (BBDs) are a common cause of breast problems in up to 30 % of women. The pathogenesis of BBD involves disturbances in the breast physiology. There is a necessity for thorough comprehensive, prompt diagnosis and management of the benign conditions to reduce the physical and psychological illness of the patients who are anxious about the possibility of the disease being a malignant one. METHODS This was a prospective study conducted in the Department of Surgical Oncology, GSL medical college from October 2016 to July 2018. Females presenting with breast lump, confirmed with fine needle aspiration cytology (FNAC), aged between 12 – 55 years and fit for surgery were included in the study. Those who did not submit the informed consent were excluded. Statistical analysis was performed by SPSS version-21 and MS Excel 2013. RESULTS Most (74 %) of the patients were between 20 and 40 years of age, 56 % were diagnosed to be fibroadenoma. In the study group, 82 % (41) participants with BBD were married. The most common presenting complaint in the study group was lump (50 %) in the breast followed by lump associated with pain (28 %). Patients with fibroadenoma mass had well defined features. CONCLUSIONS Lump was the most common clinical presentation followed by lump with pain. Based on the FNAC report, decision is made for management. Comprehensive and prompt preoperative diagnosis and management of the benign conditions is necessary to reduce the physical and psychological burden on the patients who are anxious about the possibility of malignancy. KEYWORDS Breast, Participants, Study, Age

scholarly journals Effectiveness of Antipyretic with Tepid Sponging Versus Antipyretic Alone in Febrile Children: A Randomized Controlled Trial

2018 ◽  
Vol 37 (2) ◽  
pp. 129-133
Author(s):  
Chetak Kadbasal Basavaraj ◽  
Shyamala Gowri Pocha ◽  
Ravi Mandyam Dhati
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Control Group ◽  
Study Group ◽  
Axillary Temperature ◽  
Medical College ◽  
Randomized Controlled ◽  
Significant Difference

Introduction: Fever is the most common presenting complain for which children are brought to the paediatrician.Physical methods are widely used in treating febrile children, tepid sponging being commonly practiced in hospitals along with antipyretics. The objectives of this study were to compare the effectiveness of tepid sponging and antipyretic drug versus antipyretic drug alone in febrile children.Material and Methods: This was a Randomized controlled trial done in JSS Medical College and Hospital. All children under the age of 6 months to 12 years, admitted with axillary temperature of >99oF were included in the study. A total of 500 children were included over two years study period. Children with recorded axillary temperature of >990F were randomized into control and study group by computer generated randomisation. Children in the control group received only paracetamol (15mg/kg) at 5 minutes and combined group received paracetamol and tepid sponging at five minutes. Axillary temperature was monitored every 15 minutes for a period of 2 hours in both the groups.Results: There is no significant difference in reduction of temperature between the two groups by the end of two hours. Children in combined group had a higher level of discomfort than those in only antipyretic group.Conclusion: Tepid sponging does not add to the efficacy of paracetamol in antipyresis and that addition of tepid sponging to antipyretic, results in additional discomfort for the child. This study, therefore, endorses the view that antipyretic alone without tepid sponging should be the modality of therapy in children with fever.  

scholarly journals Comparison of two ophthalmic solutions of olopatadine hydrochloride (0.1%) and epinastine hydrochloride (0.05%) on clinical signs of vernal keratoconjunctivitis and side effects of the two drugs

2020 ◽  
Vol 8 (10) ◽  
pp. 3565
Author(s):  
Tahir Husain Ansari ◽  
Yusuf Rizvi
Keyword(s):  
Side Effects ◽  
Clinical Signs ◽  
Treated Group ◽  
Vernal Keratoconjunctivitis ◽  
P Value ◽  
Medical College ◽  
Ocular Itching ◽  
Dry Climates ◽  
Ophthalmic Solutions ◽  
Olopatadine Hydrochloride

Background: Vernal keratoconjunctivitis (VKC) is a recurrent, bilateral, external, ocular inflammation primarily affecting young adults living in warm dry climates. The objectives of the research was to compare the two ophthalmic solutions of olopatadine hydrochloride (0.1%) and epinastine hydrochloride (0.05%) on clinical signs of vernal keratoconjuntivitis and to determine side effects of both the drugs.Methods: The study was carried out in 40 patients who attended the out-patient department (OPD) Ophthalmology, Darbhanga Medical College and Hospital, Laheriasarai from July 2007 to December 2008.  Forty patients with symptoms of VKC (ocular itching, ropy discharge, papillary hypertrophy, gelatinous thickening and horner-trantas spots were selected and included in our study.Results: Mean score of palpebral hyperemia at 0, 14, 28 and 42 days in olopatadine treated eye were 2.1, 1.4, 0.8 and 0.4 respectively having p value <0.01, and <0.01 and <0.05 respectively, while mean score at same stages in placebo eye were 2.1, 2, 1.9, and 1.5 having value >0.05. Epinastine treated group mean score of palpebral hyperemia were <0.01 and <0.01 respectively in epinastine treated eye whereas in placebo treated eye, mean score were 2.1, 2.0, 1.8 and 1.6 respectively having p value >0.05 in all stages. Statistically insignificant reduction at day 14 while very significant reduction at day 28 and 42 was observed in epinastine treated eye as compared to placebo.Conclusions: The present study had shown that both olopatadine and epinastine were effective in treating clinical signs of VKC as compared to placebo.

scholarly journals Topical Isotretinoin in Acne Vulgaris

2018 ◽  
Vol 29 (2) ◽  
pp. 1-5
Author(s):  
M Moksedur Rahman ◽  
M Abdullah ◽  
M Moazzem Hossain ◽  
MA Siddique ◽  
M Nessa ◽  
...  
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Prospective Study ◽  
Acne Vulgaris ◽  
Topical Therapy ◽  
Outpatient Department ◽  
College Hospital ◽  
Once Daily ◽  
Medical College ◽  
Cutaneous Reactions

This study was carried out to evaluate the efficacy, safety and adverse effects of topical isotretinoin 0.05% gel in the treatment of acne vulgaris. This prospective study was undertaken in Skin & VD outpatient department of Rajshahi Medical College Hospital, Rajshahi. One hundred patients with mild tomoderate acne vulgaris were enrolled and were instructed to apply isotretinoin 0.05% gel once daily at night for 12 weeks. Patients were followed up at 2,4,8 and 12 weeks for efficacy and tolerability. Efficacy was measured by counting facial inflammatory and noninflammatory lesions and by grading acne severity. Cutaneous tolerance was assessed by determining erythema, scaling and burning with pruritus.Response was excellent in 80%of cases.None of the cutaneous reactions was severe, all were mild and well tolerated.Nobody had to discontinue the therapy for side effects. This study confirms that isotretinoin 0.05% gel is safe and effective topical therapy for mild to moderate acnevulgaris.TAJ 2016; 29(2): 1-5

INCIDENCE OF CATARACT IN DERMATOLOGICAL PATIENTS USING STEROID CREAMS

2021 ◽  
pp. 65-66
Author(s):  
(Lt Col) Rajnish Kumar ◽  
(Lt Col) Vaka Raja Sekhar Reddy ◽  
(Lt Col) Sumit Kumar Singh ◽  
Debarshi jana
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Tertiary Care ◽  
Population Based ◽  
Topical Steroids ◽  
Study Group ◽  
Care Hospital ◽  
Ocular Side ◽  
Wide Range ◽  
The Face

Background/ Context: Corticosteroids, despite being a very effective line of treatment for various disorders is known to have a wide range of adverse effects. The use of systemic and topical steroids has been associated with cataract formation, however the ophthalmic side effects of application of steroid on skin away from the face has not been studied in depth. With increasing use of corticosteroids as rst line of therapy in treatment of various dermatological conditions, the ocular side effects, if any, of these preparations, cannot be overlooked. Aim: To study the incidence of cataract in patients using skin preparations of corticosteroids away from the face and also to correlate the dose and duration of steroid therapy to incidence of cataract. Materials & Methods: 50 patients with dermatological disorders who were being treated with dermatological steroids, on sites other than the face and periorbital region, for a period of more than six months consisted of the study group. The study group consisted of patients in the age group of 20 – 60 years. The study was conducted over a period of two years at a tertiary care hospital. Visual acuity, Slit lamp biomicroscopy, applanation tonometryand detailed fundus examination using 90D lens were carried out. Results: The incidence of cataract was signicantly higher in patients using dermatological steroids away from the face. Prolonged duration of use of these steroids also indicated a signicantly higher incidence of cataract. However, a larger population based study needs to be carried out to study the relationship between potency of steroid and incidence of cataract, although preliminary studies indicate a denite correlation between the two. Conclusions: Despite, steroids being used away from the face, there was a denite increase in the incidence of cataract. Before coming to any rm conclusions it would be advisable to reproduce the study in a larger population. However from the present pilot study it is prudent to advocate judicious use of innocuous looking steroid creams as they can cause signicant adverse effects

scholarly journals Response of systemic PUVA in vitiligo - experience with 25 cases in Combined Military Hospital, Dhaka

2015 ◽  
Vol 10 (1) ◽  
pp. 29-33
Author(s):  
ATM Rezaul Karim ◽  
Md Abdul Latif Khan ◽  
Md Sayeed Hasan ◽  
Moyassaque Ahmed ◽  
Shirajul Islam Khan ◽  
...  
Keyword(s):  
Therapeutic Response ◽  
Previous Treatment ◽  
Armed Forces ◽  
The Body ◽  
Military Hospital ◽  
Study Group ◽  
Inclusion Criteria ◽  
Medical College ◽  
Number Of Patients ◽  
Prospective Longitudinal

Introduction: It is a pigmentation disorder in which melanocytes (the cells that make pigment) in the skin are destroyed. As a result, white patches appear in the skin in different parts of the body. Objective: The objective of this study is to see the efficacy of systemic PUVA in the treatment of vitiligo patient. Methods: This is an prospective longitudinal interventional study, carried out in the depigmented area was assessed according to the department of Dermatology and Venereology, Combined Military Hospital, Dhaka in between the duration of April 2010 to March 2011. Total 25 vitiligo patients based on inclusion criteria like patient with vitiligo affecting more than 5% body surface area, patient having ivory- white fluorescence on Wood’s lamp, patient who was above 15 years of age, patient who had given written consent, patient was not taken any previous treatment etc. Results: This study showed the therapeutic response of study group after 04 weeks of therapy, 05 (20%) patients responsed Fair, 15 (60%) patients responsed Poor and no responsed by 05 (20%) patients. Therapeutic response of study group after 08 weeks of therapy showed that 15 (60%) patients responsed Fair and 10 (40%) patients responsed Poor. It was observed after 12 weeks of therapy that 13 (52%) patients responsed Poor followed by 10 (40%) patients responsed Fair and 02 (08%) patients responsed well. 29 JAFMC Bangladesh. Vol 10, No 1 (June) 2014 Therapeutic response of study group after 16 weeks of therapy was 15 (60%) patients responsed Fair, followed by 06 (24%) patients responsed Poor and 04 (16%) patients responsed Good. It was showed that after 20 weeks of therapy 13 (52%) patients responsed Fair, followed by 08 (32%) patients responsed Good, 03 (12%) patients responsed Poor and 01 (04%) patients responsed Excellent. It was observed that after 24 weeks of therapy 12 (48%) patients responsed Good, followed by 08 (32%) patients responsed Fair, 03 (12%) patients responsed Poor and 02 (08%) patients responsed Excellent. Conclusion: Systemic PUVA for the repigmentation of vitiligo seems to be effective. Study needs large number of patients for longer period of duration for confirmation of results. DOI: http://dx.doi.org/10.3329/jafmc.v10i1.22900 Journal of Armed Forces Medical College Bangladesh Vol.10(1) 2014

scholarly journals NRTIs (ZDV and d4T) side effects in PLHAs attending the antiretroviral treatment centre of B. J. Medical College Aad Civil Hospital At Ahmedabad, Gujarat, India

Retrovirology ◽  
2010 ◽  
Vol 7 (Suppl 1) ◽  
pp. P65
Author(s):  
Umesh Nihalani ◽  
Asha Shah ◽  
Burzin Kavina ◽  
Bipin Amin ◽  
Urvi Derasari ◽  
...  
Keyword(s):  
Side Effects ◽  
Antiretroviral Treatment ◽  
Civil Hospital ◽  
Medical College ◽  
Treatment Centre
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