scholarly journals Cerebral Palsy: A Unique Illustrated Experience.

2020 ◽  
pp. 1-13
Keyword(s):  
Cerebral Palsy ◽  
Developmental Delay ◽  
Motor Development ◽  
Muscle Relaxation ◽  
Birth Asphyxia ◽  
Heterogeneous Condition ◽  
Limited Mobility ◽  
History Of ◽  
Treatment Plans ◽  
Near Future

Abstract Background: Cerebral palsy is a heterogeneous condition associated with a non-progressive lesion causing permanent disorder of movement with limited mobility and is generally associated with gross motor developmental delay. In moderate to severe cases of cerebral palsy, motor developmental milestones such as walking may never be achieved. Impaired cognition and delayed speech are also commonly seen. The aim of this paper is describing our illustrated experience with cerebral palsy with emphasis on treatment with multi-factorial therapies. Patients and methods: Seventeen patients with cerebral palsy are described in this paper including two female patients whose early treatment courses were included in previous publications and 15 new cases (11 males and 4 females) observed during seven months period (May-November, 2019). Their ages ranged from 10 months to 9 years. Ten patients had significant spasticity limiting their movements. All patients had developmental delay including delayed speech. Nine patients were unable to sit without support, including a patient with significant dystonia and a patient who could stand and walk with support but was unable to sit without support. Only two patients were able to walk alone, but slowly and with difficulty. Two patients had history of birth asphyxia and one patient had a genetic condition with 2 of his brothers being affected. The patients were treated based on our published experiences with individualized treatment plans providing a combination of various interventions including nutritional support, muscle relaxants, oral pyritinol, intramuscular piracetam, citicoline (oral and injectable), intramuscular cerebrolysin and intramuscular nandrolone decanoate. The aims of these therapies include overcoming spasticity, repairing the brain and improving its function and ultimately improving mobility and advancing development. Results: All patients experienced improvement in motor development without the occurrence of any side effect. However, it was not possible to document the details of treatments and follow-up for all patients, but it was possible to provide an illustrated demonstration of improvement in seven patients. Conclusion: Cerebral palsy is a heterogeneous condition and the emergence of a single therapeutic agent that offers a comprehensive effect to improve its manifestations is very unlikely is the near future. Therefore, the use of evidence-based multi-factorial therapies is advisable. Adequate muscle relaxation is vital to prevent the complications of contractures which appear to cause a progressive disability.

scholarly journals Study of perinatal factors in children with developmental delay

2016 ◽  
Vol 4 (1) ◽  
pp. 182 ◽  
Author(s):  
Goli Sri Charan ◽  
Jayant Vagha
Keyword(s):  
Birth Weight ◽  
Developmental Delay ◽  
Gestational Age ◽  
Birth Asphyxia ◽  
Global Developmental Delay ◽  
Developmental Quotient ◽  
Birth History ◽  
History Of ◽  
Observational Descriptive Study ◽  
Birth Body Weight

Background: Birth history gives important information in children with developmental delay. Developmental challenge in children is an emerging problem across the globe, which is largely associated with improved neonatal survival. The present study highlights the importance of birth history in children with developmental delay in our hospital. The objective of this study was to study the perinatal events in children with developmental delay.Methods: Observational descriptive study was conducted on children between 6 months to 5 years who were admitted in Pediatric wards with suspected history of developmental delay. DDST II scale was performed on these children and children who failed on Denver II scale were recruited into the study. Birth history was noted in detail, if available, documentation of birth events was asked for and noted. Developmental history with developmental quotient (DQ), were noted in detail.Results: 135 children had developmental delay, 113 (83.70%) were born by vaginal delivery and 22 (16.30%) were born by caesarian section, 46 (34.18%) had no cry at birth and remaining 89 (65.92%) had normal cry at birth. 104 (77.04%) were born by term gestation and 31 (22.96%) were born preterm. Birth weight was normal in 78 (57.7%) children, LBW was seen 47 (34.81%) and 5 children each with VLBW and ELBW and 35 (25.93%) were IUGR. On comparing the children born gestational age and birth body weight with all four domains, there was no significant difference.Conclusions: Global developmental delay was more common in children born at preterm, low birth weight, IUGR and children who had birth asphyxia. Birth weight and gestational age did not significantly affect any particular domain of development. 

163 Beneficial Functional Outcomes of Selective Dorsal Rhizotomy (SDR) Are Long Lasting and Alter the Natural History of Motor Development in Spastic Cerebral Palsy

Neurosurgery ◽  
2012 ◽  
Vol 71 (2) ◽  
pp. E564-E565
Author(s):  
Roy W.R. Dudley ◽  
Michele Parolin ◽  
Bruno Gagnon ◽  
Rajeet Singh Saluja ◽  
Rita Yap ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Natural History ◽  
Motor Development ◽  
Functional Outcomes ◽  
Spastic Cerebral Palsy ◽  
Selective Dorsal Rhizotomy ◽  
Dorsal Rhizotomy ◽  
History Of

scholarly journals The natural history of gross motor development in children with cerebral palsy aged 1 to 15 years

2007 ◽  
Vol 49 (10) ◽  
pp. 751-756 ◽  
Author(s):  
E Beckung ◽  
G Carlsson ◽  
S Carlsdotter ◽  
P Uvebrant
Keyword(s):  
Cerebral Palsy ◽  
Natural History ◽  
Motor Development ◽  
Gross Motor ◽  
Gross Motor Development ◽  
Children With Cerebral Palsy ◽  
History Of

scholarly journals Psychophysical rehabilitation of children with cerebral palsy in the conditions of adaptive horseback riding

2020 ◽  
pp. 20-24
Author(s):  
G. Boyko ◽  
L. Voloshko
Keyword(s):  
Quality Of Life ◽  
Cerebral Palsy ◽  
Motor Development ◽  
Muscle Relaxation ◽  
Mental States ◽  
Motor Disorders ◽  
Horseback Riding ◽  
Formative Experiment ◽  
Children With Cerebral Palsy

The article analyzes the results of a pedagogical experiment to assess the effectiveness of the technology of using adaptive horseback riding in the psychophysical rehabilitation of children with cerebral palsy. A declarative pedagogical experiment was conducted, which consisted in determining the specifics of motor disorders of children with CP. Based on the obtained data, the pedagogical technology of using adaptive riding in the process of psychophysical rehabilitation and correction of motor disorders of children with CP is scientifically substantiated, developed and implemented in the formative experiment. The main provisions of pedagogical technology are implemented in the system of correctional classes for children with CP by adaptive riding. Technology is personality-oriented, because the main value guideline is the child's personality, motives, needs, interests, potential and abilities. A specific subject of the presented pedagogical technology is a horse, which is: as a subject of influence on the child's personality, which is provided by establishing psychological contact between the child with the CP and the animal; as a means of therapeutic effect (thermal effect, muscle relaxation, rhythm regulation, means of reducing spastic manifestations of CP, means of expanding the scope of voluntary movements, reducing mental stress, regulation of mental states of children with CP, etc.). According to the style of interaction, the proposed technology is a cooperation based on the principles of optimizing the relationship of all parties involved in the process of psychophysical development and correction of motor disorders of children with CP in terms of adaptive riding. The purpose of the presented technology is to create optimal conditions for psychophysical development and correction of motor disorders of children with CP, expanding the scope of their activities, increasing confidence in their own abilities, improving the quality of life. It is proved that the application of the presented experimental technology has a positive effect on psychophysical and motor development, the ability of children with CP, improves their quality of life.

Avaliação motora para prevenção de deficiências do bebê pré-termo e em risco de atraso no desenvolvimento / Motor evaluation for preventing disabilities on preterm babies and babies at risk of developmental delays

2020 ◽  
Vol 4 (5) ◽  
pp. 774-784
Author(s):  
Laene Jeronimo Mendes ◽  
Alice Sá Carneiro Ribeiro ◽  
Larissa Gundes Toqueti ◽  
Lucieny Almohalha
Keyword(s):  
At Risk ◽  
Child Development ◽  
Occupational Therapy ◽  
Developmental Delay ◽  
Motor Development ◽  
Developmental Delays ◽  
Early Stimulation ◽  
History Of ◽  
Age Appropriate ◽  
Preterm Babies

Introdução: O bebê de risco é considerado como aquela criança que está exposta a fatores biológicos e/ou ambientais que interferem com o desenvolvimento infantil típico e impactam a aquisição das habilidades esperados para a faixa etária dos primeiros anos de vida. Objetivo: Avaliar o desenvolvimento motor de bebês pré-termo e a termo com risco de atraso no desenvolvimento atendidos em um ambulatório de pediatria. Métodos: Trata-se de um estudo descritivo de campo, com abordagem observacional. Foram avaliados 17 lactentes de quatro, seis e oito meses de idade, com risco de atraso no desenvolvimento por meio do consentimento dos pais. Os instrumentos para coleta de dados foram um roteiro elaborado pelas pesquisadoras com perguntas relacionadas à história passada e atual dos bebês e seus pais, e a Alberta Infant Motor Scale (AIMS) para avaliação do desenvolvimento motor. Resultados: Verificou-se que dois bebês apresentaram atraso no desenvolvimento motor, três eram suspeitos de atraso e doze tiveram desenvolvimento motor normal para a idade atual. Constatou-se que os bebês que estavam em intervenção terapêutica ocupacional precoce apresentaram desenvolvimento típico em comparação aos bebês que foram assistidos apenas no serviço de rotina pediátrica. Conclusão: Destaca-se a importância da estimulação precoce nos primeiros meses de vida para prematuros e de crianças com risco de atraso no desenvolvimento, uma vez que todos as crianças que estavam no programa de estimulação precoce e recebendo as intervenções de terapia ocupacional, apresentaram desenvolvimento motor adequado para a idade. AbstractIntroduction: The baby at risk is considered as that child who is exposed to biological and/or environmental factors that interfere with the typical child development and impact the acquisition of the skills expected for the age group of the first years of life. Objective: to evaluate developmental delays in premature infants and terms of risk of developmental delay seen in a pediatric outpatient clinic. Methods: This is a descriptive field study, with an observational approach. 17 infants of four, six and eight months of age were taxed, with risk of developmental delay through parental consent. The instruments for data collection were developed by researchers with questions related to the recent and current history of their parents and parents, and an AIMS (Alberta Infant Motor Scale) to assess the development of these engines. Results: It was found that two patients had delayed motor development, three were suspected of delayed development and had normal motor development for their current age. It was found that babies who were undergoing occupational therapeutic intervention started the typical development compared to babies who were seen only in the pediatric routine service. Conclusion: The importance of early stimulation in the first months of life for premature children and those at risk of developmental delay is highlighted, since all children as children who have had no early stimulation program and receive occupational therapy assessments, age-appropriate motor development.Keywords: Child Development; Early Intervention; Occupational Therapy. ResumenIntroducción: El bebé en riesgo se considera aquel niño que está expuesto a factores biológicos y / o ambientales que interfieren con el desarrollo típico del niño e impactan la adquisición de las habilidades esperadas para el grupo de edad de los primeros años de vida. Objetivo: Evaluar posibles retrasos motores en recién nacidos prematuros y a término con riesgo de retraso en el desarrollo atendidos en una clínica ambulatoria pediátrica. Métodos: Este es un estudio de campo con un enfoque observacional y descriptivo. Diecisiete bebés de cuatro, seis y ocho meses fueron evaluados, con riesgo de retraso en el desarrollo a través del consentimiento de los padres. Los instrumentos para la recolección de datos fuero unnguión desarrollado por los investigadores con preguntas relacionadas con la historia pasada y actual de los bebés y sus padres, y la Escala motora infantil de Alberta (AIMS) para evaluar el desarrollo motor. Resultados: Se descubrió que dos bebés tenían retraso en el desarrollo motor, treseransospechosos de retraso y doce tenía nun desarrollo motor normal para la edad actual. Se descubrió que los bebés que se sometían a una intervención terapéutica ocupacional temprana mostraronun desarrollo típico en comparación con los bebés que solo fueron atendidos en el servicio de rutina pediátrico. Conclusión: Se destaca la importancia de la estimulación tempranaen los primeros meses de vida para bebés prematuros y niños en riesgo de retraso del desarrollo, ya que todos los niños que esta banenel programa de estimulación temprana y que recibieron intervenciones de terapia ocupacional mostraron desarrollo motor apropiado para la edad.Palabras clave: Desarrollo infantil, estimulación temprana, terapia ocupacional.   

scholarly journals Hereditary Spastic Paraplegia Mimicking Cerebral Palsy-Heterozygous Mutation in ALDH18A1

2021 ◽  
Author(s):  
Amit S Vatkar ◽  
Nisha Dolas ◽  
Vedashree Deshpande ◽  
Pallavi Wadhawan ◽  
Mumtaz Sharif
Keyword(s):  
Cerebral Palsy ◽  
Neurodegenerative Disorders ◽  
Birth Asphyxia ◽  
Lower Limbs ◽  
Heterozygous Mutation ◽  
Spastic Diplegia ◽  
Spastic Paraplegia ◽  
Hereditary Spastic Paraplegias ◽  
History Of ◽  
One Year

Spastic paraplegias are characterised by progressive rigidity and weakness of the lower limbs. Spastic paraplegia is a standard differential diagnosis for spastic diplegic cerebral palsy. Hereditary Spastic Paraplegias (HSP) are genetically and clinically heterogeneous group of neurodegenerative disorders causing paraplegias. Eighty forms of HSP have been noted and 64 genes have been identified. The Aldehyde Dehydrogenase 18 family member A1 (ALDH18A1) gene is located at 10q24.1 and it encodes delta-1-Pyrroline-5-Carboxylate Synthetase (P5CS), a mitochondrial bifunctional enzyme which is used for catalysing various amino acids. Mutations in this gene causes P5CS deficiency, which is responsible for neurodegenerative diseases. One should suspect neurometabolic conditions when no definite history of birth asphyxia is present in a case of cerebral palsy. Hereby, the authors report a case of a one-year-old male child with heterozygous mutation in ALDH18A1 gene resulting in spastic diplegia.

scholarly journals Clinical profile of cerebral palsy: a study from multidisciplinary clinic at tertiary care centre

2018 ◽  
Vol 5 (4) ◽  
pp. 1626
Author(s):  
Raj Kumar ◽  
Anand Kumar Gupta ◽  
Ritesh Runu ◽  
Sanjay Kumar Pandey ◽  
Manish Kumar
Keyword(s):  
Cerebral Palsy ◽  
Motor Function ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Cross Sectional Study ◽  
Spastic Diplegia ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
History Of

Background: Cerebral Palsy (CP) is combined disorder of movement, posture, and motor function and may be associated sensory, neurological and musculoskeletal complications.  It is a permanent condition attributed to nonprogressive disturbances that occurred in the developing brain. The aim of this study is to Cerebral Palsy (CP) is combined disorder of movement, posture, and motor function and may be associated sensory, neurological and musculoskeletal complications.  It is a permanent condition attributed to nonprogressive disturbances that occurred in the developing brain.Methods: Retro prospective cross-sectional study done in super speciality tertiary care centre of East India. Total 70 Children enrolled in multidisciplinary CP clinic in Physical medicine and Rehabilitation (PMR) OPD between September 2017- March 2018.Results: 78.57%male and 21.42% female, all had hospital delivery with 78.5% had normal and 21.5% caesarean section. 70% had history of birth asphyxia and 61.5% required NICU admission. 61.4% had birth wt. less than 2 kg and 10% had birth wt. less than 1kg. One fourth cases had microcephaly and one third had history of seizures. Visual abnormalities, Hearing impairment and history of jaundice were found in about one sixth children. Spastic CP was the most common (76% cases) followed by Dyskinetic 10%, Hyponic and Ataxic (1%). In spastic CP Diplegia was most common (55%), followed by Quadriplegia 24%, Hemiplegia 19% and Monoplegia 2%. GMFCS score 5 was seen in 29% (mostly quadriplegic), followed by GMFCS level 1, 21.27% (mostly hemiplegic), others mostly diplegic in level 3(19%), level 2 and 4 (14%).Conclusions: Male CP are more reaching tertiary care centre in Bihar. Perinatal factors (asphyxia) were main etiological risk factor, and Spastic Diplegia is the most common type of CP. Disability need to be detected at the earliest to facilitate a timely and appropriate intervention like early rehabilitation, special education and psycho-social support.

scholarly journals Etiology, outcomes and co-morbidities among cerebral palsy children attending tertiary care hospital, India: a prospective study

2019 ◽  
Vol 6 (3) ◽  
pp. 1023
Author(s):  
N. Dushyanth Subramaniam ◽  
Antony Jenifer ◽  
Uma Devi L. ◽  
Suresh P.
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cerebral Palsy ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Care Hospital ◽  
Maternal Risk ◽  
Prolonged Labour ◽  
History Of

Background: Cerebral palsy is the most common aetiology for motor dysfunction among children worldwide. It is associated with range of co-morbid conditions that affects the quality of life. Cerebral palsy has been studied extensively in western countries and there are only few articles available on epidemiological information in developing countries and low resource settings. This study focuses on the aetiology, risk factors, types and co-morbidities in cerebral palsy.Methods: Cerebral palsy children attending tertiary care hospital were prospectively recruited into the study. The study was conducted during January 2017 to July 2018. The cross-sectional study included complete prenatal, natal and postnatal history of the participants, BERA and Ophthalmological examinations were done.Results: One hundred and fifty children with cerebral palsy were enrolled. The mean age of participants were 36±30 months.  Male to female ratio was 2.19:1. The most common maternal risk factor among study participants was consanguinity in marriage (23.33%). 16% had prolonged labour and 10% had toxaemia during pregnancy. 47% of the children were born by institutional normal vaginal delivery. The most common neonatal risk factor was Birth Asphyxia (23%), low birth weight (20%) and neonatal sepsis (21%). 122 had spastic type of cerebral palsy. The most common morbidity associated with cerebral palsy was Gastro intestinal disturbances in 61% of the participants.Conclusions: History of prolonged labour and birth asphyxia were risk factors for cerebral palsy. Spastic CP is the most common type. Malnutrition, Gross Motor delay, Seizures, Mental retardation were the most common morbidities associated with CP. 

STUDY ON CLINICAL CHARACTERISTICS IN CHILDREN WITH CEREBRAL PALSY HUE CENTRAL HOSPITAL

2015 ◽  
pp. 44-49
Author(s):  
Nu Van Anh Ton
Keyword(s):  
Cerebral Palsy ◽  
Birth Asphyxia ◽  
Spastic Cerebral Palsy ◽  
Cross Sectional ◽  
Children With Cerebral Palsy ◽  
History Of ◽  
The Common ◽  
Saliva Flow ◽  
The Brain ◽  
Key Words Cerebral Palsy

Objective: Cerebral palsy is characterized by non-progressive abnormalities in brain, that is the real burden to family and society. Finding the signs of clinical, subclinical, disorders as well as co-morbidities in children with cerebral palsy are needed. If detected early, aggressive treatment and rehabilitation will significantly improve mobility, reduce the level of disability and the child integrate into the community. Material and methods: Children diagnosed with cerebral palsy, with cross-sectional descriptive methods. Time from 6/ 2012 to 3/2014. Results: study on 45 children with cerebral palsy: older than 36 months accounted for 60.0%; boys more than girls accounted 57.8%; seizure is the common reason the child to the hospital (accounted for the highest percentage of 24.4%). Spastic cerebral palsy can account for the highest proportion of 48.9%, ataxia may account for the lowest percentage of 2.2%; quadriplegic highest percentage of 51.1%; level V cerebral palsy (not self- activity even when have supported devices) accounted for a high proportion of 51.1%, pneumonia, seizures and saliva flow is the most common disorder in children with cerebral palsy, with a history of risk factors for birth asphyxia high proportion least 33.3%; detection epileptic wave in children with cerebral palsy through EEG high proportion of 53%, there is physical injury in the brain in children with cerebral palsy through CTscanner high percentage of 62.5%. Conclusion: To avoid the risk of cerebral palsy, special asphyxia, and do the EEG records, imaging diagnostic to identify clearly brain lesions for better outcome. Key words: Cerebral palsy

scholarly journals A CROSS-SECTIONAL STUDY OF CLINICAL PROFILE OF CEREBRAL PALSY PATIENTS VISITING A GOVERNMENT TERTIARY CARE HOSPITAL FROM MAHARASHTRA, INDIA

2020 ◽  
pp. 1-5
Author(s):  
Smita Mundada ◽  
Tejas Mandlecha ◽  
Prabha Khaire ◽  
Shilpa Pawar
Keyword(s):  
Cerebral Palsy ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Common Finding ◽  
Periventricular White Matter ◽  
Care Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
History Of

Cerebral palsy has emerged as one of the major causes of childhood disability in India. In low and middle income countries there are gaps in knowledge in the spheres of epidemiological research, intervention and service utilization. AIMS AND OBJECTIVES: This study describes the clinical features associated problems of children with CP visiting a government tertiary care Hospital from Maharashtra, India. Materials and Methods: This was cross sectional retrospective observational study conducted on 78 children of cerebral palsy. Result: Among 78 enrolled children, maximum 50%(n=39) of children were between1-3yr age group with male to female ratio was 1.05:1. History of consanguinity was seen in 35.9% (n=28) subjects, 69.2%(n=54)of subjects were from the urban area. 78.2% (n=61) subjects were born term , 65.3%(n=51) cases had a history of NICU stay with the most common etiological factor being birth asphyxia seen in 38.4 %( n=30) subjects followed by sepsis in 29.5% subjects (n=23). Most common type of cerebral palsy was spastic 87.1% followed by dyskinetic 10.2%. Most of the participants were at GMFCS level IV and V (23.1% and 47.4% respectively). 78.2% subjects were having feeding problems, 43.6% had associated epilepsy. Majority of our subjects had Microcephaly (69.2%) and malnutrition (74.3%). MRI was done in only 34.6% of subjects with most common finding being periventricular white matter injury (PVWMI)). Conclusion: It is suggested that rehabilitation clinics should be set up for CP patients at every government medical college so that parents can be made aware of the disease, handicaps, prognosis, and management.

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