scholarly journals SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDY OF VANGA BHASMA PREPARED WITH SPECIAL REFERENCE TO RASATARANGINI

2021 ◽  
pp. 1-16
Author(s):  
Raman Belge ◽  
Rameshwar Pandey ◽  
Prakash Itankar
Keyword(s):  
Antimicrobial Activity ◽  
Special Reference ◽  
Tin Oxide ◽  
Analytical Techniques ◽  
Klebsiella Pneumonia ◽  
Nano Particle ◽  
Xrd Study ◽  
Sem Study ◽  
Fungal Organisms ◽  
Organoleptic Parameters

Vanga Bhasma which has been prepared with Parada and Haratala or even without Parada and Haratala is widely used for a broad spectrum of diseases. It is also said to possess Jantughna Prabhava (Antimicrobial activity). Hence it was decided to synthesize, analyse and study the antimicrobial activity of Vanga Bhasma prepared with special reference to Rasatarangini 18/25-28. The present study deals with the preparation of Vanga Bhasma with reference to Rasatarangini 18/25-28. The synthesized Bhasma samples were characterized by various analytical techniques. The antimicrobial effects of these Bhasma samples were studied. The samples were characterized with the contemporary parameters like XRD, SEM and EDX to find out the nature of the Vanga Bhasma samples. These samples were further tested against certain Gram +ve, Gram-ve and fungal organisms, so as to find out the anti-microbial efficacy of the Vanga Bhasma samples. The adopted method for preparation of Vanga Bhasma (Ref. Rasatarangini 18/25-28) was able to produce a Bhasma compatible to organoleptic parameters mentioned in the ancient texts. Formation of the small sized particles as small as a nano-particle was confirmed by SEM study. Average 14 Putas are required to prepare Vanga Bhasma and XRD study confirms that Tin oxide is the major compound. Vanga Bhasma showed antimicrobial activity in inhibiting the growth of Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia, Escherichia coli and Candida albicans with a concentration of 100mg/ml. This outcome further supports the Krumighna and Jantughna properties (anti-microbial activity) of Vanga Bhasma.

scholarly journals PHARMACEUTICO-ANALYTICAL AND ANTIMICROBIAL STUDY OF JARIT VANGA BHASMA PREPARED WITH SPECIAL REFERENCE TO RASATARANGINI

2021 ◽  
Vol 10 (3) ◽  
pp. 61-71
Author(s):  
Raman Belge ◽  
Rameshwar Pandey ◽  
Prakash Itankar
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Candida Albicans ◽  
Special Reference ◽  
Microbial Activity ◽  
Quality Parameters ◽  
Klebsiella Pneumonia ◽  
Sem Study

Background: Vanga Bhasma is said to possess antimicrobial activity (Jantughna Prabhava). Hence it was decided to evaluate the antimicrobial activity of Jarit Vanga Bhasma (JVB) prepared with special reference to Rasatarangini 18/29-33. Objectives: JVB was synthesized, analysed and its antimicrobial effects were studied in Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia, Escherichia coli and Candida albicans. Materials and Methods: The JVB was prepared and analyzed for the quality parameters mentioned in the Ayurvedic texts as well as the modern parameters like XRD, SEM and EDX to find out the nature of the Vanga Bhasma samples. The anti-microbial study was done to find out the anti-microbial efficacy of the JVB samples. Results and Conclusions: The adopted method for preparation of JVB was able to produce a Bhasma compatible to organoleptic parameters mentioned in the ancient texts. The obtained JVB was grayish white with the formation of the small sized particles as small as a nanoparticle which was confirmed by SEM study. XRD study confirms that Tin oxide is the major compound found in all the JVB samples. JVB showed antimicrobial activity in inhibiting the growth of Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia, Escherichia coli and Candida albicans with a concentration of 100mg/ml. The mean zone of inhibition was 12.33mm, 12.33mm, 14.66mm, 10.33mm and 16mm respectively. This outcome further supports the Krumighna and Jantughna properties (Anti-microbial activity) of Vanga Bhasma. Hence, JVB is said to possess Anti-Microbial activity.

scholarly journals Indium Tin Oxide Nanocomposites – Green Synthesis, Characterization, Morphology and Optical Properties Using Almond Gum

2021 ◽  
Vol 11 (1) ◽  
pp. 3134-3141
Keyword(s):  
Optical Properties ◽  
Ir Spectra ◽  
Green Synthesis ◽  
Tin Oxide ◽  
Indium Tin Oxide ◽  
Crystal Size ◽  
Xrd Study ◽  
Vis Spectroscopy ◽  
Sem Study ◽  
Ft Ir

In this present study, Tin doped In2O3 metal oxide was synthesized by green synthesis using almond gum as a reducing agent. The prepared Nanocomposite (Ncs) was characterized by TG-DTA, XRD, SEM, EDX, FTIR, and UV-Vis spectroscopy. From TG-DTA able to get some information regarding calcination temperature. This was found out to be over 300 °C. The XRD study revealed that the In2O3-SnO2nanocomposite with crystal size 13 nm to 16 nm. The SEM study revealed that the morphology of prepared nanocomposite is Cubic phased sphere structure, and EDAX data show that elements in the composite of In2O3-SnO2 are O 74.71%, In 23.45%, and Sn 1.84%. FT-IR spectra confirm the formation of the In-O-In and Sn-O-Sn type of bonding. The UV-Vis spectra imply the bandgap of generated In2O3- Sno2Ncs is 3.83ev.

scholarly journals Green Synthetic Protocol for (E)-1-Aryl-3-(2-morpholinoquinolin- 3-yl)prop-2-en-1-ones and Their Antimicrobial Activity

2019 ◽  
Vol 31 (9) ◽  
pp. 1895-1898
Author(s):  
Relangi Siva Subrahmanyam ◽  
Venkateswara Rao Anna
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Data ◽  
1H Nmr ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
In Vitro Antimicrobial Activity ◽  
Mass Spectral ◽  
Fungal Organisms

We report here an easy, efficient and green synthetic protocol for the (E)-1-aryl-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones by the Claisen-Schmidt condensation of 2-morpholinoquinoline-3-carbaldehyde and different substituted acetophenones by using 1-butyl-3-methylimidazolium tetrafluoroborate (Bmim)BF4. The compounds were characterized by using 1H NMR, 13C NMR and mass spectral data and screened there in vitro antimicrobial activity against different bacterial and fungal organisms.

Efficiency of different microalgae as monospecific and bispecific diets in larval rearing of Penaeus indicus with special reference to growth, nutrient composition and antimicrobial activity of microalgae

2021 ◽  
Author(s):  
Kizhakkekarammal Puthiyedathu Sandeep ◽  
Satheesha Avunje ◽  
Jagabattula Syama Dayal ◽  
Changaramkumarth Paran Balasubramanian ◽  
Paramita Banerjee Sawant ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Special Reference ◽  
Nutrient Composition ◽  
Larval Rearing ◽  
Penaeus Indicus

scholarly journals EVALUATION OF IN VITRO ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITY OF AQUEOUS AND METHANOLIC SEED EXTRACTS OF CITRULLUS LANATUS

2017 ◽  
Vol 9 (5) ◽  
pp. 29
Author(s):  
Iswariya S. ◽  
Uma T. S.
Keyword(s):  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Aqueous Extract ◽  
Seed Extract ◽  
Inflammatory Activity ◽  
Diffusion Method ◽  
Klebsiella Pneumonia ◽  
Anti Inflammatory ◽  
Seed Extracts

Objective: The present study was designed to identify the bioactive phytochemicals and its antibacterial and in vitro anti-inflammatory potential of aqueous and methanolic seed extract of Citrullus lanatus.Methods: The phytochemical screening of both the aqueous and methanolic seed extract was carried out qualitatively to identify the major Phyto-constituents present in the extracts. The antimicrobial activity of the extracts was evaluated against six pathogenic bacterial strains by agar well diffusion method and the Minimum inhibitory concentration (MIC) was determined by broth dilution method. In vitro anti-inflammatory activity of C. lanatus seed extracts was evaluated by using human red blood cell (HRBC) membrane stabilization and inhibition of albumin denaturation method.Results: The results of the study indicated that both the extracts of the seed having antimicrobial activity, while the methanolic extract showed more significant activity against the tested organism than aqueous extract. Methanol extract had the lowest MIC of 1.562 mg/ml against Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa and Bacillus subtilis, whereas in aqueous extract was highly sensitive to Bacillus subtilis, E. coli and Klebsiella pneumonia with MIC of 3.125 and 6.25 mg/ml, respectively. Methanolic extracts exerted comparative higher anti-inflammatory activity than aqueous extract.Conclusion: Present study provides a firm evidence to support that the synergistic effect of C. lanatus seed extracts having potent anti-inflammatory and antimicrobial property, which might serve as an effective drug for various microbial infections and inflammatory disorders.

scholarly journals Extraction and Characterization of Silver Nitrate Modified Biopolymer and its Antimicrobial Mode of Action

2021 ◽  
pp. 50-62
Author(s):  
Jeje O. Ayorinde ◽  
Osula J. Eghosa
Keyword(s):  
Antimicrobial Activity ◽  
Silver Nitrate ◽  
Mode Of Action ◽  
Proximate Analysis ◽  
Klebsiella Pneumonia ◽  
Crab Shell ◽  
Agno3 Solution ◽  
Antimicrobial Evaluation ◽  
Ft Ir ◽  
Crab Shell Waste

Biopolymer (chitosan) was isolated from crab shell waste through the processes of demineralization, deproteinization, decolourization and deacetylation. The resulting chitosan (CHS) was further treated with silver nitrate (AgNO3) solution at various concentrations (0.5, 1.0 and 1.5 M) in order to enhance the antimicrobial activity of chitosan. The crab shell powder (CSP) and (CHS) were characterized using X-ray Diffractometer (XRD), Fourier Transform Infrared (FT-IR), and Scanning Electron Microscopy coupled with Energy Dispersive Spectroscopy (SEM-EDS). The antimicrobial mode of action of AgNO3 treated chitosan was performed using serial dilution (1:2) technique for minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) and tested against four microorganisms (Escherichia coli, Klebsiella pneumonia, Staphlococcusaureus and Pseudopodium). The result of proximate analysis of CHS and chitin (CHN) showed % crude protein to be 12.24±001 and 20.54±0.03 respectively, % ash was found to be 4.1±0.01 for CHS and 3.80±0.01 for CHN. The FTIR spectra of CHS and CHN showed their characteristic absorption peaks and the diffractograms of CSP and CHS showed CaCO3 to be the major mineral present in the samples. The antimicrobial evaluation revealed that untreated chitosan extract (UCHSE) showed no antimicrobial activity against the four tested microorganisms. The results of MIC and MBC showed that the organisms responded to the antimicrobial agent at different dilution concentration. It was observed that CHS treated with 0.5 M AgNO3 (0.5 SNCHSE) inhibited the growth of E. coli at 1000 µg/mL, S. aureus at 500 µg/mL while it exhibited bactericidal (MBC) activity against all the organisms at 1000 µg/mL.

scholarly journals VARIATIONS IN ANTIMICROBIAL ACTIVITY OF SYZYGIUM CUMINI OF DIFFERENT GEOGRAPHICAL LOCATIONS

2020 ◽  
pp. 1-6
Author(s):  
Pratibha ◽  
Nesari Tanuja ◽  
Ghildiyal Shivani ◽  
Vandhana
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Candida Albicans ◽  
Streptococcus Pyogenes ◽  
Antimicrobial Agents ◽  
Diffusion Method ◽  
Klebsiella Pneumonia ◽  
Syzygium Cumini ◽  
Geographical Variations ◽  
Geographical Locations

The emergence of antibiotic resistance and the evolution of new strains of disease causing agents, are of highly concern to the global health community. Plants are potential source of antimicrobial agents. They have been used traditionally for prevention of infections caused by micro-organisms. Description of Krimighana herbs enumerated in Ayurveda classics is suggestive towards the importance of this group of medicine. Jambu (Syzygium cumini (L.) Skeels) is a member of Myrtaceae family. In Raja Nighantu it is mentioned that plant Jambu is having Kriminashaka property. It has been widely used medicine in the prevention of various ailments like cough, Dysentary, Diabetes, inflammation and ringworm. It is well established fact that geographical variations effects the potential and activity of medicinal herbs. Hence, the present study was undertaken to investigate Syzygium cumini procured from different geographical locations including Delhi, Rajasthan and Maharashtra for their potential activity against human infections caused by pathogens. Method The aqueous extract of Syzygium cumini of all the three areas was prepared. The activity of the plant extract was evaluated against nine bacterial pathogens and one fungal strain, which include Staphyllococcus aureus, Streptococcus pyogenes, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Klebsiella pneumonia and Candida albicans. The activity was carried out using Disk diffusion method. Result and Conclusion: All samples of Syzygium cumini showed potential antimicrobial activity against four pathogens including Staphyllococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa and Candida albicans. MIC was also evaluated against the tested pathogenic strains. The sample from Maharashtra showed MIC i.e. 80µg, 40µg, 80µg against Staphyllococcus aureus, Streptococcus pyogenes and Candida albicans respectively which is less as compare to sample from Rajasthan and Delhi. Region wise sample from Maharashtra showed good ZOI and MIC.

scholarly journals Physicochemical Properties and Antimicrobial Activity of Evaporated Extract of Cow Dung Against Some Pathogens

2012 ◽  
Vol 5 (1) ◽  
pp. 135-141
Author(s):  
M. Waziri ◽  
J. S. Suleiman
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Inhibitory Concentration ◽  
Analytical Techniques ◽  
Food Additive ◽  
Cow Dung ◽  
Northern Nigeria ◽  
Elemental Contents ◽  
Mic Value

The evaporated extract of cow dung is traditionally used in Northern Nigeria and Cameroun as food additive and in treatment of infectious diseases. In this study, the cow dung ash extract was prepared and tested for some elemental contents as well as the antimicrobial activity against Cyanobacteria (C.bacteria), Staphylococcus aureus (S.aureus), Bacillus subtilis (B.subtilis) and Escherichia coli (E.coli) using different analytical techniques. The extract was highly basic with pH of 11.7 and the elements vary in the following decreasing order of concentration; K>Na>Mg>Ca>Fe>Al>Zn.  S. aureus was the most sensitive bacteria with minimum inhibitory concentration (MIC) value of 0.082 mg/mL while B. subtilis was the least sensitive with MIC value of 4.3 mg/mL. The result of this study indicate that the extract can supplement the dietary Na and K requirements for the users and supports the folkloric use of the extract in treatment of infections.© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v5i1.11962        J. Sci. Res. 5 (1), 135-141 (2013)

Comparative studies of the antimicrobial effect of ethanolic and aqueous extracts of Garcinia kola on Klebsiella pneumonia and Candida albicans in vitro

2021 ◽  
Vol 16 (1) ◽  
pp. 52-58
Author(s):  
Elizabeth Winful ◽  
Olanikpekun Idowu ◽  
Opeoluwa O. Fasanya ◽  
Nkechi E. Egbe
Keyword(s):  
Antimicrobial Activity ◽  
Candida Albicans ◽  
Ethanol Extract ◽  
Antimicrobial Effect ◽  
Klebsiella Pneumonia ◽  
Disc Diffusion ◽  
Diffusion Test ◽  
Garcinia Kola ◽  
Zones Of Inhibition

Antimicrobial resistance has become a global health problem. Although a wide range of chemotherapeutic antimicrobials are available for treatment of microbial related infections and diseases, development of resistance to these chemotherapeutic agents is rapidly on the increase. Extracts from some plants have shown some promise in antimicrobial activity. This has led to the screening of several medicinal plants for their potential antimicrobial activity. Therefore, this study was aimed at evaluating the antimicrobial effect of ethanolic and aqueous extracts of Garcinia kola against Klebsiella pneumonia and Candida albicans in vitro. The Garcinia kola seeds extracts were obtained using 70% ethanol and distilled water respectively. Phytochemical screening of Garcinia kola revealed the presence of various potent phytochemicals such as tannins, saponins, flavonoids, alkaloids and glycosides. Both extracts of the seeds were investigated for antimicrobial activity using disc diffusion and agar well diffusion sensitivity tests. The ethanol extract produced zones of inhibition of about 7.3 mm for Candida albicans only at a concentration of 800mg/ml for the disc diffusion test. For the agar well diffusion test, the aqueous extract produced zones of inhibition of about 9.5 mm, while the ethanol extract produced zone of inhibition of 19 mm against Candida albicans at a concentration of 800 mg/ml. However, at the same concentration, the ethanol extract produced zones of inhibition of about 8.5 mm against Klebsiella pneumoniae. The findings of this study revealed that Garcinia kola was not effective in treating Klebsiella pneumonia infections but has potential in treating Candida albicans infections. Keywords: Garcinia kola, Klebsiella pneumonia, Candida albicans

scholarly journals In vitro Antimicrobial Properties and Chemical Composition of Santolina chamaecyparissus Essential Oil from Algeria

2012 ◽  
Vol 7 (7) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Samah Djeddi ◽  
Khadidja Djebile ◽  
Ghania Hadjbourega ◽  
Zoubida Achour ◽  
Catherine Argyropoulou ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Candida Albicans ◽  
Chemical Composition ◽  
Essential Oil ◽  
Antimicrobial Properties ◽  
Klebsiella Pneumonia ◽  
Aerial Parts

The chemical composition of the essential oil obtained from the aerial parts of Santolina chamaecyparissus L., growing in Algeria, was investigated by GC-MS analyses. A total of 36 compounds were identified, accounting for 91.7% of the essential oil obtained. Camphor (31.1%) and cubenol (17.0%) were the predominant compounds. The potential of the antimicrobial activity was also investigated and the tested sample proved to be very active against Klebsiella pneumonia and Candida albicans (34.1 ± 0.02 mm and 35.0 ± 0.01 mm, respectively). Transverse sections of the leaf and stem of the plant suggest that the essential oil is localized in endogenous and exogenous sites.

Sign in / Sign up

Export Citation Format

Share Document