Silent hypoxemia in a patient with severe SARS-CoV-2 pneumonia

2020 ◽  
Vol 11 (2) ◽  
pp. 87-91
Author(s):  
A. D. Palman ◽  
D. A. Andreev ◽  
S. A. Suchkova
Keyword(s):  
Oxygen Saturation ◽  
Well Being ◽  
Multiple Organ ◽  
The Novel ◽  
Subjective Well Being ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Objective Criterion ◽  
Long Time ◽  
Severe Lung

Patients with COVID-19 are typically characterized by severe lung injury with the development of acute respiratory failure. However, in some patients, subjective well-being may remain relatively satisfactory for a long time and, despite severe hypoxemia, they do not complain of shortness of breath. Case report. We observed a 65-year-old man hospitalized with severe SARS-CoV-2 pneumonia, low level of blood oxygen saturation, but at the same time without complaints of shortness of breath. Only as the disease progressed with a decrease in oxygen saturation when breathing atmospheric air (SpO2 ) lower than 85% he began to notice a feeling of lack of air. The patient’s condition worsened and as a result, he died in the intensive care unit from multiple organ failure. Discussion. This case clearly illustrates one more feature of the course of pneumonia associated with the novel SARSCoV-2 coronavirus and shows that SpO2 measurement is one of the leading objective criterion that allows a doctor to assess the real severity of a patient’s condition with COVID-19.

scholarly journals The Safety of Hyperbaric Oxygen Therapy in the Treatment of Covid-19

2020 ◽  
Vol 9 (3) ◽  
pp. 314-320
Author(s):  
O. A. Levina ◽  
A. K. Еvseev ◽  
A. K. Shabanov ◽  
V. V. Kulabukhov ◽  
N. Y. Kutrovskaya ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Hyperbaric Oxygenation ◽  
Well Being ◽  
Blood Oxygen ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Soft Modes ◽  
Before And After ◽  
Coronavirus Infection ◽  
Positive Effect

Relevance. Acute respiratory infection COVID-19 caused by the SARS-CoV-2 (2019-nCov) coronavirus is severe and extremely severe in 15—20% of cases, which is accompanied by the need for respiratory support. Hyperbaric oxygenation is recognized as an effective therapy for replenishing any form of oxygen debt.Aim of study. To study the safety of HBO use in patients with COVID-19.Material and metods. We examined 32 patients with the diagnosis “Coronavirus infection caused by the virus SARS-CoV-2” (10 — moderately severe patients (CT 1–2), 22 — patients in serious condition (CT 3–4), who received course of hyperbaric oxygenation (HBO). The procedures were carried out in a Sechrist 2800 chamber (USA) at a mode of 1.4–1.6 AT for no more than 60 minutes. In total, the patients received 141 HBO sessions. Before and after each HBO session, the subjective indicators of the patient’s condition were assessed and the blood oxygen saturation was measured.Results. An algorithm for HBO course management was developed, which consists in using “soft” modes (up to 1.4 AT) during the first session, followed by pressure adjustment (not higher than 1.6 AT) during the course to achieve maximum therapeutic effect and comfort for the patient. Against the background of the HBO course, the patients showed an increase in blood oxygen saturation in patients in both surveyed groups, as well as positive dynamics in the form of a decrease in shortness of breath, an improvement in general well-being.Conclusion. The inclusion of daily sessions (at least 4) of hyperbaric oxygenation in “soft” modes (1.4–1.6 ATA) in the complex therapy for COVID-19 has shown its safety and preliminary positive effect on the subjective state of the examined patients and the dynamics of blood oxygen saturation.

scholarly journals Therapeutic and Vaccine Options for COVID-19: Status after 6 Months of the Disease Outbreak

2020 ◽  
pp. 247255522097957
Author(s):  
Dawid Maciorowski ◽  
Christian Ogaugwu ◽  
Subba Rao Durvasula ◽  
Ravi Durvasula ◽  
Adinarayana Kunamneni
Keyword(s):  
Cardiovascular Diseases ◽  
Nasal Congestion ◽  
Chronic Respiratory Disease ◽  
Disease Outbreak ◽  
New Drugs ◽  
The Novel ◽  
General Malaise ◽  
Shortness Of Breath ◽  
Long Time ◽  
Approved Drugs

An outbreak of the coronavirus disease 2019 (COVID-19) caused by an infection of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, China, in December 2019. This new virus belongs to the group of enveloped RNA beta-coronaviruses. Symptoms may differ in various infected persons, but major presentations include dry cough, nasal congestion, shortness of breath, fever, and general malaise. The disease appears to be more severe in patients above the age of 60 years and those with underlying conditions such as diabetes, cancer, cardiovascular diseases, chronic respiratory disease, and hypertension. There is still no approved vaccine against COVID-19, but more than a hundred are at different stages of development. It is known that the development of new drugs takes a relatively long time, so several known and already-approved drugs are being repurposed for the treatment of this disease. In this review, we explore the therapeutic and vaccine options that are available for COVID-19 6 months after its outbreak. Most noteworthy among the therapeutic options are dexamethasone, remdesivir, Avigan (favipiravir) and convalescent plasma.

scholarly journals Effects of Irritability of the Youth on Subjective Well-Being: Mediating Effect of Coping Styles

2020 ◽  
Author(s):  
Ling ZHANG ◽  
Benxian YAO ◽  
Xiaodan ZHANG ◽  
Hao XU
Keyword(s):  
Urban Youth ◽  
Coping Style ◽  
Positive Response ◽  
Coping Styles ◽  
Family Members ◽  
Well Being ◽  
Mediating Effect ◽  
Subjective Well Being ◽  
Problematic Behaviors ◽  
Long Time

Background: The global COVID-19 pandemic caused great impacts and influences to human psychology. As a result, youths who are kept at home for a long time easily develop irritability and problematic behaviors. However, relatively little attention has been paid to the relations among irritability, coping style, and subjective well-being of the youth. Methods: Overall, 1,033 youth respondents (aged 18–30 yr) from seven provinces in China were investigated in 2020 using the irritability, depression, and anxiety scale, coping style scale, and well-being index scale. Results: Among the dimensions of irritability of the youth, anxiety received the highest score, followed by introversion irritability, extroversion irritability, and depression. Irritability had significant regional differences. The total score of irritability among rural youth was significantly higher than that of urban youth (P<0.05). The irritability level of youths with parents’ emotional status was harmonious and good relations with family members and peers was far lower than those of youths who have poor relations between parents, family members, and peers (P<0.05). The irritability level of youths with a lower monthly household income was higher (P<0.05). Irritability of the youth had significantly negative correlations with positive response and SWB, and it had a significantly positive correlative with negative response. Coping style can mediate the relationship between irritability and SWB of the youth to some extent. Conclusion: Significant correlations exist among irritability, coping style, and SWB of the youth. Irritability can be used to predict SWB indirectly through positive response.

scholarly journals Predictor of Severity of Lung Injury and Oxygen Saturation in COVID- 19 Patients

2021 ◽  
pp. 107-114
Author(s):  
Fahimeh Shahjooie ◽  
Sadrollah Mahmudi ◽  
Somayeh Mohammadi ◽  
Hassan Goodarzi ◽  
Mehrdad Farajy ◽  
...  
Keyword(s):  
Lung Injury ◽  
Oxygen Saturation ◽  
Significant Relationship ◽  
Wide Spectrum ◽  
Severe Disease ◽  
Cross Sectional Study ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Cross Sectional ◽  
Early Management

Introduction: Wide spectrum of clinical features of COVID-19 was seen from mild to severe. This is very important to determine the severity of disease, early management of severe disorder may increase the chance of survival. Methods: This cross sectional study perform on 150 patients with mean age of 53 years that refer to from 21 February to 19 April 2020. Result: The most comorbidity disease HTN, DM and IHD with prevalence of 26.2%, 20%, 11.3% which had higher severity of lung disease. There was a significant relationship between age, lymphopenia, CRP, IHD, DM, shortness of breath and body pain with the severity of lung injury, shortness of breath had higher severity of lung injury but myalgia had a lower severity rather than the others.  level of the LDH was associated with chest CT scan score and so severe disease Further results showed that the mean±SD of LDH in 3 CT group were 576.30±214.82, 641.89± 277.07, 919.92± 382.14 in CT score less than 20, 20-50 and more than 50 respectively (P=0.002). According this study there was significant relationship between age, BMI, CRP, shortness of breath and fever with blood oxygen saturation. Further results showed that the correlation between LDH and oxygen saturation was r=-0.31 (p=0.002)

Oxidative stress and inflammation in COVID-19 pathogenesis

2020 ◽  
Vol 26 (4) ◽  
Author(s):  
Vladimir G. Kukes ◽  
Olga K. Parfenova ◽  
Nikita G. Sidorov ◽  
Yuri V. Olefir ◽  
Albina А. Gazdanova
Keyword(s):  
Oxidative Stress ◽  
Severe Acute Respiratory Syndrome ◽  
Oxygen Saturation ◽  
Viral Infections ◽  
Blood Oxygen ◽  
The Novel ◽  
Blood Oxygen Saturation ◽  
Metabolic Products ◽  
Respiratory Viral Infections

This study discusses the role of oxidative stress and inflammation in the development of severe acute respiratory syndrome (SARS) associated with COVID-19 caused by the novel SARS-CoV-2 coronavirus. An analysis of the literature revealed that the development of respiratory viral infections, including COVID-19, is usually accompanied by the accumulation of acidic metabolic products in the blood and tissues and, accordingly, oxidative stress and increased levels of cytokines. In this regard, it seems appropriate to use the second-generation low-toxic antioxidant Ethoxidol, manufactured in Russia, which reduces the intensity of inflammation, and also improves blood oxygen saturation.

scholarly journals A Novel Severity Scoring Derived from Chest Radiographic Findings in COVID 19 Patients Admitted to a COVID Care University Hospital in India

2021 ◽  
pp. 17-25
Author(s):  
Abhijit Mahavir Patil ◽  
Meenakshi Bhakare ◽  
Sundeep Salvi
Keyword(s):  
Oxygen Saturation ◽  
Clinical Severity ◽  
Host Cells ◽  
University Hospital ◽  
Disease Spread ◽  
Blood Oxygen ◽  
The Novel ◽  
Blood Oxygen Saturation ◽  
Radiographic Findings ◽  
Radiographic Score

Coronavirus (COVID 19) disease predominantly affects the Respiratory system and cause by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV2). It enters into the host cells via angiotensin-converting enzyme-2 (ACE-2), a part of the renin-angiotensin system (RAS) found in the epithelium of the nasal, lungs. Aim: Chest Radiographic findings in COVID-19 patients detected for COVID care. Applying the novel chest radiographic scoring in disease-spread patients is admitted to the COVID care center and its correlation with blood oxygen saturation (SpO2) and clinical severity. Objective: 1) To apply the novel chest radiographic scoring in patients of COVID 19 infection are admitted to our Covid Care Centre and 2) To apply its correlation with blood oxygen saturation (SpO2) and clinical severity. Results: 1) We found a moderate negative correlation between the chest radiographic score and SpO2. 2) Weak positive correlation between Clinical grading and CxR score. Conclusion: Chest radiographic score taking into account the nature of opacities and extent is useful in classifying the patients into mild-moderate, severe, and critical grades. Take-home Message: A chest radiograph can be used as a baseline radiological investigation in COVID 19 patients as it can help to triage them according to the severity and treat them accordingly.

scholarly journals Respiratory Rehabilitation After Blood Transfusion in a COVID-19 Patient: A Case Report

2020 ◽  
Author(s):  
Mohammad Javad Mousavi ◽  
Narges Obeidi ◽  
Saeed keshmiri ◽  
Farzan Azodi ◽  
Jamile Kiyani ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Oxygen Delivery ◽  
Severe Pneumonia ◽  
Upper Respiratory Tract ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Invasive Approach ◽  
Packed Red Blood Cells ◽  
Hospital Facility ◽  
History Of

Abstract Background: The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been identified as the most crucial threat of the century. Due to severe pneumonia and acute respiratory distress syndrome (ARDS), the SARS-CoV-2 can cause shortness of breath, hypoxemia, and the need to mechanical ventilation, intensive care unit (ICU) management, and eventual death. We have tried to use a non-invasive approach to prevent patient from needing respiratory support with invasive ventilation (IV). Here, for the first time, improvement of oxygen delivery and oxygen saturation levels were observed in a COVID-19 patient using packed red blood cells (PRBCs) transfusion.Case presentation: A 63-year-old man with a history of smoking and addiction who came to our hospital facility with fever, shortness of breath and decreased blood oxygen saturation. High-resolution chest CT revealed bilateral and multifocal ground-glass opacities consistent with COVID-19. Subsequently, the COVID-19 infection was confirmed by real-time polymerase chain reaction (qRT-PCR) assay of the upper respiratory tract. Conclusions: Oxygen delivery and oxygen saturation improvement were observed in the COVID-19 patient, after PRBCs transfusions.

Financial well-being for a sustainable society: a road less travelled

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Mandeep Mahendru
Keyword(s):  
Financial Literacy ◽  
Well Being ◽  
Behavioural Economics ◽  
Integrative Approach ◽  
Subjective Well Being ◽  
Financial Capability ◽  
Content Type ◽  
Rational Decision Making ◽  
Long Time

PurposeMeasurement of financial well-being has remained a challenge for the governments for a long time. This paper responds to this challenge by taking an integrative approach, whereby the previous conceptualizations of financial well-being are examined. Further, we propose a new conceptualization of financial well-being using the parameters of objective and subjective well-being.Design/methodology/approachWe conduct a widespread review of the literature with regard to the linkage between financial literacy and financial capability.FindingsNumerous studies report the pertinent role of behavioural economics in rational decision making. This paper understands the role of behavioural economics in regard to financial well-being.Research limitations/implicationsEmpirical investigation in measuring the linkage between financial literacy and financial capability needs to be developed to achieve the goal of financial well-being.Originality/valueThis paper makes a noble contribution to the literature by proposing a new conceptualization of financial well-being spread over financial literacy, financial capability and psychological factors.

scholarly journals Subjective Well-Being in Healthcare Professionals in Colombia: On the Constitution of Subjectivity and the Ethics of Care in Times of the COVID-19 Pandemic

2021 ◽  
Vol 12 ◽  
Author(s):  
Diego Fernando Barragán-Giraldo ◽  
Giovanni Anzola-Pardo ◽  
Maura Andrea Guerrero-Lucero
Keyword(s):  
Healthcare Professionals ◽  
Narrative Research ◽  
Digital Technologies ◽  
Ethics Of Care ◽  
Well Being ◽  
The Other ◽  
The Novel ◽  
Subjective Well Being ◽  
Reconnaissance Survey ◽  
Postgraduate Studies

The purpose of this work is to reveal how subjective well-being has been generated in a group of professionals in the healthcare field in Colombia, who carried out postgraduate studies at the time of the pandemic caused by the novel SARS-CoV-2 coronavirus in a synchronous and remote learning course facilitated by employing digital technologies. Two methods were assumed, one was qualitative, taking into account some elements of narrative research and discourse analysis, and the other was quantitative, through a rapid reconnaissance survey. The research assumes the constitution of subjectivity from memory and everyday life, as well as the ethics of care concerning caring for oneself and others, as categories that were (re)signified with the narratives—and as notions that make up a theoretical corpus—to understand subjective well-being.

Attaccamento ai luoghi, identitŕ giovanile e benessere: una ricerca in Europa e implicazioni per la comunicazione interculturale

IKON ◽  
2009 ◽  
pp. 39-65
Author(s):  
Paolo Inghilleri ◽  
Nicola Rainisio
Keyword(s):  
Place Attachment ◽  
Satisfaction With Life ◽  
Well Being ◽  
Place Identity ◽  
Satisfaction With Life Scale ◽  
Subjective Well Being ◽  
Cultural Groups ◽  
Significant Difference ◽  
Long Time ◽  
The Difference

- This paper investigates the connections between place attachment, Well-being and cultural differences in students of three European countries: Italy, Uk and Romania. A sample of 445 participants was investigated on a number of issues, including reported Well-being (using the Satisfaction with Life Scale), place identity, place attachment and place preferences. The results show an existing direct link between place attachment and life satisfaction; this relationship becomes stronger during the adolescence. A second cluster of data shows an emerging need to integrate and to balance global and local sense of belonging to improve the subjective Well-being. The last evidence concerns the perceived place identity, because there's a significant difference in managing the place meanings between cultural groups. In particular, the difference we found regards subjects who consider themselves citizens of other countries while residing in the three countries examined, and as such they presumably belong to linguistic and ethnic groups of long-time or recent immigration. This findings demonstrated the utility of the integration between Environmental and Positive Psychology, with the aim to investigate the suggested happiness-place links. The implications for new intercultural communication's strategies are discussed.

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