scholarly journals Respiratory Rehabilitation After Blood Transfusion in a COVID-19 Patient: A Case Report

2020 ◽  
Author(s):  
Mohammad Javad Mousavi ◽  
Narges Obeidi ◽  
Saeed keshmiri ◽  
Farzan Azodi ◽  
Jamile Kiyani ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Oxygen Delivery ◽  
Severe Pneumonia ◽  
Upper Respiratory Tract ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Invasive Approach ◽  
Packed Red Blood Cells ◽  
Hospital Facility ◽  
History Of

Abstract Background: The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been identified as the most crucial threat of the century. Due to severe pneumonia and acute respiratory distress syndrome (ARDS), the SARS-CoV-2 can cause shortness of breath, hypoxemia, and the need to mechanical ventilation, intensive care unit (ICU) management, and eventual death. We have tried to use a non-invasive approach to prevent patient from needing respiratory support with invasive ventilation (IV). Here, for the first time, improvement of oxygen delivery and oxygen saturation levels were observed in a COVID-19 patient using packed red blood cells (PRBCs) transfusion.Case presentation: A 63-year-old man with a history of smoking and addiction who came to our hospital facility with fever, shortness of breath and decreased blood oxygen saturation. High-resolution chest CT revealed bilateral and multifocal ground-glass opacities consistent with COVID-19. Subsequently, the COVID-19 infection was confirmed by real-time polymerase chain reaction (qRT-PCR) assay of the upper respiratory tract. Conclusions: Oxygen delivery and oxygen saturation improvement were observed in the COVID-19 patient, after PRBCs transfusions.

scholarly journals Automatic Oxygen Delivery System for Premature Babies

2010 ◽  
Vol 4 (2) ◽  
Author(s):  
Thao P. Do ◽  
Lindsey J. Eubank ◽  
Devin S. Coulter ◽  
John M. Freihaut ◽  
Carlos E. Guevara ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Oxygen Concentration ◽  
Delivery System ◽  
Pulse Oximeter ◽  
Oxygen Delivery ◽  
Supplemental Oxygen ◽  
Saturation Level ◽  
Blood Oxygen ◽  
Blood Oxygen Saturation ◽  
Oxygen Saturation Level

When an infant is born prematurely, there are a number of health risks. Among these are underdeveloped lungs, which can lead to abnormal gas exchange of oxygen or hypoxemia. Hypoxemia is treated through oxygen therapy, which involves the delivery of supplemental oxygen to the patient but there are risks associated with this method. Risks include retinopathy, which can cause eye damage when oxygen concentration is too high, and brain damage, when the concentration is too low [1]. Supplemental oxygen concentration must be controlled rigorously. Currently healthcare staff monitors infants’ blood oxygen saturation level using a pulse oximeter. They manually adjust the oxygen concentration using an air-oxygen blender. Inconsistent manual adjustments can produce excessive fluctuations and cause the actual oxygen saturation level to deviate from the target value. Precision and accuracy are compromised. This project develops an automatic oxygen delivery system that regulates the supplemental oxygen concentration to obtain a target blood oxygen saturation level. A microprocessor uses a LABVIEW® program to analyze pulse oximeter and analyzer readings and control electronic valves in a redesigned air-oxygen blender. A user panel receives a target saturation level, displays patient data, and signals alarms when necessary. The prototype construction and testing began February 2010.

Symptom Analysis of Confirmed Covid-19 Patients Managed at Allied Hospitals of Rawalpindi Medical University, Pakistan

1970 ◽  
Vol 9 (4) ◽  
pp. 235-241
Author(s):  
Javeria Malik ◽  
Muhammad Khurram ◽  
Arsalan Manzoor Mughal ◽  
Noman Ahmed Chaudhary ◽  
Qaiser Aziz ◽  
...  
Keyword(s):  
Age Groups ◽  
Severe Pneumonia ◽  
Cross Sectional Study ◽  
Upper Respiratory Tract ◽  
Shortness Of Breath ◽  
Cross Sectional ◽  
Duration Of Symptoms ◽  
Presenting Symptoms ◽  
Persistent Cough ◽  
Medical University

Introduction Coronavirus can cause respiratory disease ranging from mild upper respiratory tract illness to severe pneumonia, severe acute respiratory distress syndrome, and death. The purpose of this research was to study the symptoms of confirmed Coronavirus disease (COVID-19) cases and their relationship with gender and age groups. Materials and Methods This observational cross-sectional study was conducted at Rawalpindi Institute of Urology and Transplantation (RIUT) that is the COVID-19 management center of Rawalpindi Medical University, Rawalpindi during the month of March 2020. Consecutive sampling methodology was used, and all real-time polymerase chain reaction (RT-PCR) confirmed patients of COVID-19 were included. Data regarding age, gender, and symptoms with onset was recorded and analyzed.  Results Thirty-five patients, 22 (62.9%) males, and 13 (37.1%) females were included. Seven (20%) patients were ≥60 years old, and 12 (34.8%) ≥40 years old. 21 (60%) were symptomatic and the rest of them were asymptomatic. The mean duration of symptoms was 2.8±1.1 days. Fever (13, 61.9%), persistent cough (12, 57.1%), sputum (6, 28.6%), shortness of breath (4, 19%), anorexia (3, 14.3%), fatigue (3, 14.3%), myalgia (1, 4.8%), were presenting symptoms. Cough, anorexia, and fatigue were significantly more frequent in the patients ≥40 of age. Anorexia and fatigue were common in the age groups ≥40 and ≥60 years. Myalgia was significantly frequent in patients aged ≥60 years. Conclusion Fever, persistent cough and shortness of breath are commonest symptoms of COVID 19 patients. COVID-19 can be asymptomatic in many cases.

Silent hypoxemia in a patient with severe SARS-CoV-2 pneumonia

2020 ◽  
Vol 11 (2) ◽  
pp. 87-91
Author(s):  
A. D. Palman ◽  
D. A. Andreev ◽  
S. A. Suchkova
Keyword(s):  
Oxygen Saturation ◽  
Well Being ◽  
Multiple Organ ◽  
The Novel ◽  
Subjective Well Being ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Objective Criterion ◽  
Long Time ◽  
Severe Lung

Patients with COVID-19 are typically characterized by severe lung injury with the development of acute respiratory failure. However, in some patients, subjective well-being may remain relatively satisfactory for a long time and, despite severe hypoxemia, they do not complain of shortness of breath. Case report. We observed a 65-year-old man hospitalized with severe SARS-CoV-2 pneumonia, low level of blood oxygen saturation, but at the same time without complaints of shortness of breath. Only as the disease progressed with a decrease in oxygen saturation when breathing atmospheric air (SpO2 ) lower than 85% he began to notice a feeling of lack of air. The patient’s condition worsened and as a result, he died in the intensive care unit from multiple organ failure. Discussion. This case clearly illustrates one more feature of the course of pneumonia associated with the novel SARSCoV-2 coronavirus and shows that SpO2 measurement is one of the leading objective criterion that allows a doctor to assess the real severity of a patient’s condition with COVID-19.

scholarly journals Predictor of Severity of Lung Injury and Oxygen Saturation in COVID- 19 Patients

2021 ◽  
pp. 107-114
Author(s):  
Fahimeh Shahjooie ◽  
Sadrollah Mahmudi ◽  
Somayeh Mohammadi ◽  
Hassan Goodarzi ◽  
Mehrdad Farajy ◽  
...  
Keyword(s):  
Lung Injury ◽  
Oxygen Saturation ◽  
Significant Relationship ◽  
Wide Spectrum ◽  
Severe Disease ◽  
Cross Sectional Study ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Cross Sectional ◽  
Early Management

Introduction: Wide spectrum of clinical features of COVID-19 was seen from mild to severe. This is very important to determine the severity of disease, early management of severe disorder may increase the chance of survival. Methods: This cross sectional study perform on 150 patients with mean age of 53 years that refer to from 21 February to 19 April 2020. Result: The most comorbidity disease HTN, DM and IHD with prevalence of 26.2%, 20%, 11.3% which had higher severity of lung disease. There was a significant relationship between age, lymphopenia, CRP, IHD, DM, shortness of breath and body pain with the severity of lung injury, shortness of breath had higher severity of lung injury but myalgia had a lower severity rather than the others.  level of the LDH was associated with chest CT scan score and so severe disease Further results showed that the mean±SD of LDH in 3 CT group were 576.30±214.82, 641.89± 277.07, 919.92± 382.14 in CT score less than 20, 20-50 and more than 50 respectively (P=0.002). According this study there was significant relationship between age, BMI, CRP, shortness of breath and fever with blood oxygen saturation. Further results showed that the correlation between LDH and oxygen saturation was r=-0.31 (p=0.002)

Risk Factors for Perioperative Adverse Respiratory Events in Children with Upper Respiratory Tract Infections

2001 ◽  
Vol 95 (2) ◽  
pp. 299-306 ◽  
Author(s):  
Alan R. Tait ◽  
Shobha Malviya ◽  
Terri Voepel-Lewis ◽  
Hamish M. Munro ◽  
Monica Siewert ◽  
...  
Keyword(s):  
Risk Factors ◽  
Oxygen Saturation ◽  
Breath Holding ◽  
Upper Respiratory Tract ◽  
Asymptomatic Children ◽  
Respiratory Events ◽  
History Of ◽  
Upper Respiratory ◽  
Tract Infections ◽  
Adverse Respiratory Events

Background Anesthesia for the child who presents for surgery with an upper respiratory infection (URI) presents a challenge for the anesthesiologist. The Current prospective study was designed to determine the incidence of and risk factors for adverse respiratory events in children with URTs undergoing elective surgical procedures. Methods The study population included 1,078 children aged 1 month to 18 yr who presented for an elective surgical procedure. Parents were given a short questionnaire detailing their child's demographics, medical history, and presence of any symptoms of a URT. Data regarding the incidence and severity of perioperative respiratory events were collected prospectively. Adverse respiratory events (any episode of laryngospasm, bronchospasm, breath holding > 15 s, oxygen saturation < 90%, or severe cough) were recorded. In addition, parents were contacted 1 and 7 days after surgery to determine the child's postoperative course. Results There were no differences between children with active URIs, recent URIs (within 4 weeks), and asymptomatic children with respect to the incidences of laryngospasm and bronchospasm. However, children with active and recent URIs had significantly more episodes of breath holding, major desaturation (oxygen saturation < 90%) events, and a greater incidence of overall adverse respiratory events than children with no URIs. Independent risk factors for adverse respiratory events in children with active URIs included use of an endotracheal tube (< 5 yr of age), history of prematurity, history of reactive airway disease, paternal smoking, surgery involving the airway, the presence of copious secretions, and nasal congestion. Although children with URIs had a greater incidence of adverse respiratory events, none were associated with any long-term adverse sequelae. Conclusions The current study identified several risk factors for perioperative adverse respiratory events in children with lulls. Although children with acute and recent URIs are at greater risk for respiratory complications, these results suggest that most of these children can undergo elective procedures without significant increase in adverse anesthetic outcomes.

scholarly journals Silent hypoxia: a frequently overlooked clinical entity in patients with COVID-19

2020 ◽  
Vol 13 (9) ◽  
pp. e237207 ◽  
Author(s):  
Atanu Chandra ◽  
Uddalak Chakraborty ◽  
Jyotirmoy Pal ◽  
Parthasarathi Karmakar
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Distress ◽  
Oxygen Saturation ◽  
Wide Spectrum ◽  
Severe Pneumonia ◽  
Upper Respiratory Tract ◽  
Low Oxygen ◽  
Severe Hypoxaemia ◽  
Upper Respiratory

COVID-19 caused by SARS-CoV-2 may present with a wide spectrum of symptoms ranging from mild upper respiratory tract infection like illness to severe pneumonia and death. Patients may have severe hypoxaemia without proportional features of respiratory distress, also known as ‘silent’ or ‘apathetic’ hypoxia. We present a case of a 56-year-old man with COVID-19 who presented to the fever clinic of our institution with fever and cough without any respiratory distress but low oxygen saturation. The patient deteriorated over the next 2 days but eventually recovered of his illness in due course of time. This case demonstrates ‘silent hypoxia’ as a possible presentation in COVID-19 and emphasises the importance of meticulous clinical examination including oxygen saturation measurements in suspected or confirmed patients.

scholarly journals The Safety of Hyperbaric Oxygen Therapy in the Treatment of Covid-19

2020 ◽  
Vol 9 (3) ◽  
pp. 314-320
Author(s):  
O. A. Levina ◽  
A. K. Еvseev ◽  
A. K. Shabanov ◽  
V. V. Kulabukhov ◽  
N. Y. Kutrovskaya ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Hyperbaric Oxygenation ◽  
Well Being ◽  
Blood Oxygen ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Soft Modes ◽  
Before And After ◽  
Coronavirus Infection ◽  
Positive Effect

Relevance. Acute respiratory infection COVID-19 caused by the SARS-CoV-2 (2019-nCov) coronavirus is severe and extremely severe in 15—20% of cases, which is accompanied by the need for respiratory support. Hyperbaric oxygenation is recognized as an effective therapy for replenishing any form of oxygen debt.Aim of study. To study the safety of HBO use in patients with COVID-19.Material and metods. We examined 32 patients with the diagnosis “Coronavirus infection caused by the virus SARS-CoV-2” (10 — moderately severe patients (CT 1–2), 22 — patients in serious condition (CT 3–4), who received course of hyperbaric oxygenation (HBO). The procedures were carried out in a Sechrist 2800 chamber (USA) at a mode of 1.4–1.6 AT for no more than 60 minutes. In total, the patients received 141 HBO sessions. Before and after each HBO session, the subjective indicators of the patient’s condition were assessed and the blood oxygen saturation was measured.Results. An algorithm for HBO course management was developed, which consists in using “soft” modes (up to 1.4 AT) during the first session, followed by pressure adjustment (not higher than 1.6 AT) during the course to achieve maximum therapeutic effect and comfort for the patient. Against the background of the HBO course, the patients showed an increase in blood oxygen saturation in patients in both surveyed groups, as well as positive dynamics in the form of a decrease in shortness of breath, an improvement in general well-being.Conclusion. The inclusion of daily sessions (at least 4) of hyperbaric oxygenation in “soft” modes (1.4–1.6 ATA) in the complex therapy for COVID-19 has shown its safety and preliminary positive effect on the subjective state of the examined patients and the dynamics of blood oxygen saturation.

Effects of Hot Environment on Human Oxygen Delivery under Different Labor Intensity

2012 ◽  
Vol 610-613 ◽  
pp. 695-698
Author(s):  
Yu Ping Sun ◽  
Neng Zhu
Keyword(s):  
Relative Humidity ◽  
Oxygen Saturation ◽  
Oxygen Delivery ◽  
Thermal Environment ◽  
Climatic Conditions ◽  
Blood Oxygen ◽  
Blood Oxygen Saturation ◽  
Thermal Environments ◽  
Hot Environment ◽  
Light Medium

In this study, the blood oxygen saturation of 10 volunteers performing light, medium and heavy physical labors were examined under different climatic conditions in a chamber. The climatic conditions referred to one group of comfort environment (25°C dry bulb temperature and 50% relative humidity) and three groups of thermal environment (30°C, 35°C, 40°Cdry bulb temperature and 90% relative humidity). The results reveal the blood oxygen saturation of subjects performing same physical labor decreased in different thermal environments, the values within normal variations. The blood oxygen saturation of subjects performing different physical labors decreased in same environmental condition, the values also within normal variations. It shows in conditions of 30~40°C, 90%relative humidity, human bodies under light, medium and heavy physical labors ingested less oxygen compared with the thermal comfort environment. And it indicates the human body oxygen delivery is decreasing and in anaerobic condition in hot environment.

Excess oxygen delivery during muscle contractions in spontaneously hypertensive rats

1995 ◽  
Vol 78 (1) ◽  
pp. 101-111 ◽  
Author(s):  
J. M. Lash ◽  
H. G. Bohlen
Keyword(s):  
Blood Flow ◽  
Oxygen Saturation ◽  
Oxygen Delivery ◽  
Spontaneously Hypertensive Rats ◽  
Muscle Contractions ◽  
Hypertensive Rats ◽  
Hemoglobin Oxygen Saturation ◽  
Spontaneously Hypertensive ◽  
Tissue Po2 ◽  
Wistar Kyoto

These experiments determined whether a deficit in oxygen supply relative to demand could account for the sustained decrease in tissue PO2 observed during contractions of the spinotrapezius muscle in spontaneously hypertensive rats (SHR). Relative changes in blood flow were determined from measurements of vessel diameter and red blood cell velocity. Venular hemoglobin oxygen saturation measurements were performed by using in vivo spectrophotometric techniques. The relative dilation [times control (xCT)] of arteriolar vessels during contractions was as large or greater in SHR than in normotensive rats (Wistar-Kyoto), as were the increases in blood flow (2 Hz, 3.50 +/- 0.69 vs. 3.00 +/- 1.05 xCT; 4 Hz, 10.20 +/- 3.06 vs. 9.00 +/- 1.48 xCT; 8 Hz, 16.40 +/- 3.95 vs. 10.70 +/- 2.48 xCT). Venular hemoglobin oxygen saturation was lower in the resting muscle of SHR than of Wistar-Kyoto rats (31.0 +/= 3.0 vs. 43.0 +/- 1.9%) but was higher in SHR after 4- and 8-Hz contractions (4 Hz, 52.0 +/- 4.8 vs. 43.0 +/- 3.6%; 8 Hz, 51.0 +/- 4.6 vs. 41.0 +/- 3.6%). Therefore, an excess in oxygen delivery occurs relative to oxygen use during muscle contractions in SHR. The previous and current results can be reconciled by considering the possibility that oxygen exchange is limited in SHR by a decrease in anatomic or perfused capillary density, arteriovenular shunting of blood, or decreased transit time of red blood cells through exchange vessels.

scholarly journals PSIX-9 Impacts of bunk management on feedlot performance, carcass characteristics, hydrogen sulfide concentration and blood oxygen saturation in steers fed 25 or 50% modified distillers grains plus solubles

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 422-422
Author(s):  
Rebecca L Moore ◽  
Cierrah J Kassetas ◽  
Leslie A LeKatz ◽  
Bryan W Neville
Keyword(s):  
Hydrogen Sulfide ◽  
Oxygen Saturation ◽  
Management Strategy ◽  
Distillers Grains ◽  
Feed Ratio ◽  
Sulfide Concentration ◽  
Blood Oxygen ◽  
Blood Oxygen Saturation ◽  
Feedlot Performance ◽  
Arterial Blood

Abstract One hundred and twenty-six yearling angus steers (initial body weight 445.87 ± 7.13 kg) were utilized in a 2 x 2 factorial design to evaluate the impacts of bunk management and modified distillers grains plus solubles (mDGS) inclusion on feedlot performance, hydrogen sulfide concentrations and blood oxygen saturation. Treatments included bunk management strategy either control bunk management (CON; clean bunks at the time of next day’s feeding) or long bunk management (LONG; feed remaining at time of next day’s feeding), and two inclusion rates of mDGS either 25% or 50% (DM Basis). On d 0, 7, 14, 21, 28 and 35 rumen gas samples were collected via rumenocentesis, and arterial blood samples were collected on two steers from each pen. No differences (P ≥ 0.09) were observed for dry matter intake, average daily gain and gain-to-feed ratio for bunk management or mDGS inclusion. Hot carcass weight, ribeye area, marbling score and quality grade were not affected (P ≥ 0.48) by either bunk management or mDGS inclusion. Back fat was greater (P = 0.04) for CON steers compared to LONG (1.30 vs 1.12 ± 0.05cm, respectively), but was not affected (P = 0.59) by mDGS inclusion. Steers on CON had greater (P = 0.03) yield grades compared to LONG (3.21 vs 2.96 ± 0.11, respectively). Bunk management strategy did not impact hydrogen sulfide concentrations or blood oxygen saturation (P = 0.82). Hydrogen sulfide concentrations increased (P < 0.001) with increasing mDGS inclusion. Blood oxygen saturation was influenced by day of sampling (P = 0.01). Blood oxygen saturation was not affected (P = 0.07) by mDGS inclusion. The fact that ruminal hydrogen sulfide concentrations increased while blood oxygen saturation remained similar raises questions about the quantity of hydrogen sulfide and metabolic fate of excess hydrogen sulfide in the blood of ruminant animals.

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