scholarly journals Acute tonsillitis in children: nuances in differential diagnosis

2021 ◽  
Vol 2 (7) ◽  
pp. 16-20
Author(s):  
Vladimir Tatochenko ◽  
Keyword(s):  
Differential Diagnosis ◽  
Antibiotic Therapy ◽  
Respiratory Disease ◽  
Infectious Mononucleosis ◽  
Viral Disease ◽  
Older Children ◽  
Acute Tonsillitis ◽  
Parapharyngeal Abscess ◽  
Pfapa Syndrome ◽  
Clinical Cases

Currently, acute tonsillitis remains the most prevalent pediatric respiratory disease. The disease most often occurs in children up to 4 years of age, and in children of this age it is exclusively a viral disease; the viral tonsillitis contribution in older children is 60-80%. However, despite these figures, survey of physicians and parents, as well as audit indicate that the rate of prescribing antibiotics to children with acute tonsillitis is 90-95%, which means that the majority of children receive unnecessary antibiotic therapy. Appropriate differential diagnosis of the diseases, involv-ing the pharynx and tonsils, is a top priority for practicing otolaryngologists and pediatricians. The paper reports rare clinical cases of parapharyngeal abscess, adenoviral tonsillitis, infectious mononucleosis, PFAPA syndrome.

scholarly journals Extraosseous Ewing’s Sarcoma: Pictorial Review of Imaging Findings, Differential Diagnosis, and Pathologic Correlation

2021 ◽  
Author(s):  
Alan Alexander ◽  
Kyle Hunter ◽  
Michael Rubin ◽  
Ambarish P. Bhat
Keyword(s):  
Differential Diagnosis ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Multimodality Imaging ◽  
Imaging Features ◽  
Older Children ◽  
Radiologic Findings ◽  
Pictorial Review ◽  
Malignant Mesenchymal Tumor ◽  
Extraosseous Ewing’S Sarcoma

AbstractExtraosseous Ewing’s sarcoma (EES), first described in 1969, is a malignant mesenchymal tumor just like its intraosseous counterpart. Although Ewing’s sarcomas are common bone tumors in young children, EESs are rarer and more commonly found in older children/adults, often carrying a poorer prognosis. We discuss the multimodality imaging features of EES and the differential diagnosis of an aggressive appearing mass in proximity to skeletal structures, with pathologic correlates. This review highlights the need to recognize the variability of radiologic findings in EES such as the presence of hemorrhage, rich vascularity, and cystic or necrotic regions and its imaging similarity to other neoplasms that are closely related pathologically.

EVALUATING THE EFFICACY OF HUMAN BRONCHIECTASISBASED ANTIBIOTIC THERAPY IN THE TREATMENT OF ORANGUTAN RESPIRATORY DISEASE SYNDROME

2021 ◽  
Vol 52 (4) ◽  
Author(s):  
Agnes P. Sriningsih ◽  
Nancy P. Lung ◽  
Fransiska Sulistyo ◽  
Stuart A. Aronson ◽  
Riley K. Aronson ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Respiratory Disease

TETANY AND PARATHYROID HYPERPLASIA IN THE NEWBORN INFANT: INFLUENCE OF DIETARY PHOSPHATE LOAD

PEDIATRICS ◽  
1952 ◽  
Vol 9 (5) ◽  
pp. 534-543
Author(s):  
LYTT I. GARDNER
Keyword(s):  
Differential Diagnosis ◽  
Cause Of Death ◽  
Newborn Infant ◽  
Newborn Infants ◽  
Parathyroid Hyperplasia ◽  
Similar Data ◽  
Older Children ◽  
Inorganic P ◽  
Dietary Phosphate ◽  
The Relationship

Three cases of newborn tetany are described, pointing out the relationship between dietary phosphate load and the manifestations of this disease. An additional three newborn infants are described who showed other symptomatology than tetany in association with dietary phosphate load. [See Table 1 in Source Pdf]. Data concerning diet, cause of death and degree of parathyroid hyperplasia are tabulated in eight newborns who were found to have parathyroid hyperplasia at autopsy. Similar data are tabulated on eight newborns and five older children who were found to have normal parathyroid glands at autopsy. Several other factors possibly involved in newborn tetany and newborn parathyroid hyperplasia are discussed. The importance of measuring serum inorganic P in the differential diagnosis of neonatal distress is pointed out.

Cytokine production and clinical and laboratory aspects of EBV-associated acute infectious mononucleosis in children

2021 ◽  
Vol 19 (1) ◽  
pp. 58-63
Author(s):  
J.-C. Khakizimana ◽  
◽  
V.N. Timchenko ◽  
V.P. Novikova ◽  
O.P. Gurina ◽  
...  
Keyword(s):  
Infectious Mononucleosis ◽  
Cytokine Production ◽  
Enzyme Linked Immunosorbent Assay ◽  
Interferon Α ◽  
Acute Tonsillitis ◽  
Cervical Lymph Nodes ◽  
Group I ◽  
Tnf Α ◽  
Group Ii ◽  
Acute Infectious Mononucleosis

Objective. To analyze clinical and laboratory parameters, as well as the dynamics of cytokine production in children of different ages with acute infectious mononucleosis caused by Epstein-Barr virus (EBV mononucleosis). Patients and methods. We examined two groups of patients: group I included 20 children aged 1 to 7 years, whereas group II included 29 children aged 8 to 17 years. All study participants were tested in the acute phase of the disease and in early convalescence. We evaluated serum levels of interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-α (TNF-α), and interferon-α (IFN-α) using enzyme-linked immunosorbent assay (ELISA) (standard Vektor-Best kits, Russia). Data analysis was performed using Microsoft Excel 2019 for Windows and IBM SPSS statistics; we applied the methods of non-parametric statistics. Differences were considered significant at p < 0.05. Results. The majority of children had fever, intoxication, acute tonsillitis, and enlarged cervical lymph nodes. Laboratory makers, such as lymphocytosis, neutropenia, and thrombocytopenia were more pronounced in children from group II. In both groups, the level of cytokines in the acute period of the disease was higher than the discriminatory one. In early convalescence, patients from group I demonstrated more significant reduction in the cytokine level than patients from group II (р < 0.05). In children over 7 years of age, the levels of IL-10 and TNF-α positively correlated with the disease duration (p < 0.01 and p < 0.05, respectively) Conclusion. The level of cytokine production in acute EBV mononucleosis depends on patients’ age. Concentrations of IL-10 and TNF-α can serve as markers reflecting the severity of EBV mononucleosis and can be used for disease prognosis. Key words: EBV mononucleosis, children, cytokines, IL-6, IL-10, TNF-α, IFN-α

scholarly journals Chronic otitis media following infection by non-O1/non-O139 Vibrio cholerae: A case report and review of the literature

2020 ◽  
Vol 10 (3) ◽  
pp. 186-191
Author(s):  
Sara M. Van Bonn ◽  
Sebastian P. Schraven ◽  
Tobias Schuldt ◽  
Markus M. Heimesaat ◽  
Robert Mlynski ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Differential Diagnosis ◽  
Case Report ◽  
Antibiotic Therapy ◽  
Vibrio Cholerae ◽  
Otitis Media ◽  
Chronic Otitis Media ◽  
Aquatic Environments ◽  
Review Of The Literature ◽  
Intestinal Infections

AbstractWe report a case of a chronic mesotympanic otitis media with a smelly purulent secretion from both ears and recurrent otalgia over the last five years in a six-year-old girl after swimming in the German Baltic Sea. Besides Staphylococcus aureus a non-O1/non-O139 Vibrio cholerae strain could be isolated from patient samples. An antibiotic therapy with ciprofloxacin and ceftriaxone was administered followed by atticotomy combined with tympanoplasty. We conclude that V. cholerae should not be overlooked as a differential diagnosis to otitis infections, especially when patients present with extra-intestinal infections after contact with brackish- or saltwater aquatic environments.

scholarly journals Clinical and immunological peculiarity of acute Epstein-Barr virus infection in adults

2016 ◽  
Vol 21 (3) ◽  
pp. 130-135
Author(s):  
A. A Trisko ◽  
Marina G. Avdeeva ◽  
N. V Kolesnikova
Keyword(s):  
Viral Hepatitis ◽  
Infectious Mononucleosis ◽  
Acute Viral Hepatitis ◽  
Control Group ◽  
Epstein Barr Virus Infection ◽  
Acute Tonsillitis ◽  
Pronounced Increase ◽  
Barr Virus ◽  
First Case ◽  
Significant Difference

The goal - improving the quality of the diagnosis of acute infectious mononucleosis (IM) in adults on the basis of a comparative study of cytokine status in MI, acute tonsillitis and acute viral hepatitis. Materials and methods. We observed three groups of patients hospitalized in «Specialized Clinical Hospital of Infectious Diseases of the Ministry of Health of the Krasnodar Territory» in 2012-2014: 29 patients with myocardial infarction (group 1), 25 - with acute tonsillitis (group 2), 19 - with acute viral hepatitis (group 3) and the control group. The groups were matched by sex, age and severity of the disease. In the acute phase of the disease the level of cytokines IL-1a, IL-1β, RaIL-1, IL-4, INF-y in serum was studied by ELISA. Results. At the height of the infectious mononucleosis increased content of IL-1a, IL-1β and INF-y was observed. In acute viral hepatitis significant increase in IL-1β, a less pronounced increase in INF-y, and no increase in IL-1a were registered. Acute tonsillitis is characterized by no increase in IL-1a and smaller increase in INF-y, compared to infectious mononucleosis. Significant difference between infectious mononucleosis and acute tonsillitis was a considerable rise of IL-1a and INF-y in first case. Acute viral hepatitis differs from infectious mononucleosis with pronounced increase in IL-1β. Conclusion. Determined significant intergroup cytokine status differences in patients with infectious mononucleosis, acute tonsillitis, and acute viral hepatitis may be helpful as additional diagnostic criteria for well examined infections in adults.

scholarly journals Systemic antibiotic therapy of patients with acute bacterial sinusitis taking into account resistance

2021 ◽  
pp. 172-177
Author(s):  
S. V. Starostina ◽  
D. A. Sivokhin
Keyword(s):  
Antibiotic Therapy ◽  
Severe Disease ◽  
Viral Disease ◽  
Systemic Antibiotic ◽  
Systemic Antibiotic Therapy ◽  
Causative Agents ◽  
Intracranial Complications ◽  
Acute Bacterial Rhinosinusitis ◽  
Third Line ◽  
The Right

Acute rhinosinusitis is one of the most common diseases in the world. According to statistics, about 10 million cases are registered in Russia every year.Acute bacterial rhinosinusitis (ABRS) in most cases develops as a result of an acute respiratory viral disease, proceeds easily and it does not require antibiotic therapy. However, it significantly reduces the patient's quality of life in cases of moderate and severe disease, and in the absence of timely treatment, can lead to intracranial complications (meningitis, encephalitis, intracranial abscesses, etc.) and orbital (reactive edema of the eyelid, phlegmon of the orbit, periorbital abscesses, etc.). To avoid complications, with exacerbation of rhinosinusitis, it is necessary to choose the right antibiotic therapy, taking into account the resistance of the microorganisms that caused the disease.The article describes the differential diagnosticprinciples of bacterial rhinosinusitis according to the latest recommendations and research in this area, the most common antibiotic-resistant pathogens in the practice of an ENT doctor are presented, the issue of choosing the correct systemic antibiotic therapy for the treatment of patients with moderate and severe acute bacterial rhinosinusitis is considered according to modern data on the sensitivity of bacterial pathogens to antibacterial drugs prescribed in the otorhinolaryngologist's practice. The article presents data on a new universal cephalosporin of the 3rd generation (the active ingredient is cefditoren), as a second- and third-line drug, due to its high activity against most causative agents of acute bacterial rhinosinusitis, and clinical observation using the above antibacterial agent within the framework of the considered topics.

scholarly journals Control integral del PRRSv mediante el concepto de las 5 fases: revisión crítica

2021 ◽  
Vol 35 ◽  
Author(s):  
Ruben Sala Echave ◽  
Rebeca López-Úbeda ◽  
Guillermo Ramis ◽  
Iván Hernández Caravaca
Keyword(s):  
Respiratory Disease ◽  
Semen Quality ◽  
Viral Disease ◽  
Porcine Respiratory ◽  
Phase Process

El Síndrome Reproductivo y Respiratorio Porcino (PRRSV) es una enfermedad viral que causa importantes pérdidas económicas y productivas, afectando la reproducción en cerdas gestantes, la calidad del semen en verracos y, ocasionando enfermedad respiratoria en lechones en transición y cebo, reduciendo el crecimiento de los cerdos y provocando un aumento de la mortalidad. Este síndrome cuenta con diversas cepas patógenas, muchas de ellas no incluidas en las actuales vacunas. En consecuencia, los cerdos nunca estarán completamente protegidos frente a esta enfermedad, debido a la capacidad permanente de recombinación y mutación propia del virus. El proceso de las 5 fases surge fruto de la experiencia y la búsqueda de desarrollar metodologías que unifiquen criterios y herramientas de diagnóstico, prevención y bioseguridad para el control de esta enfermedad. En conclusión, la plataforma de las 5 fases hace posible el abordaje en conjunto de la enfermedad, sirviendo como herramienta integral de utilidad para el control exitoso de esta enfermedad. Porcine Respiratory and Reproductive Syndrome is a viral disease, which causes important economic and productive losses, affecting reproduction in pregnant sows, semen quality in boars and, causing respiratory disease in growing and fattening piglets, reducing pig growth and causing increased mortality. This syndrome is caused by several pathogenic strains, many of which are not included in current vaccines. Consequently, pigs will never be completely protected against this disease, due to the permanent recombination and mutation capacity of the virus. The five-phase process is the result of experience and the search to develop methodologies that unify criteria and tools for diagnosis, prevention and biosecurity for the control of this disease. In conclusion, the 5-phases platform makes it possible to approach the disease as a whole, providing it as an integral tool for success on this disease.

Sign in / Sign up

Export Citation Format

Share Document