Clinico-demographic Characteristics of Patients with Cirrhosis of Liver : Experienced at a Tertiary Care Hospital

2013 ◽  
Vol 20 (Number 1) ◽  
pp. 8-14
Author(s):  
AKM S Kabir ◽  
Md. F Alam ◽  
C K Ghosh ◽  
S N Ahmed ◽  
S Sikder

Cirrhosis of liver is one of the commonest hepatobiliary problems in Bangladesh as well as in global perspective. The purpose of the present study was to find out the clinico-demographic characteristics of liver cirrhosis patients admitted at a tertiary care hospital. Patients who are clinically suspected to have cirrhosis of liver, admitted in medicine units of Holy Family Red Crescent Medical College Hospital, Dhaka have been analyzed regarding clinical presentation and complications profile. Total 100 patients were included of which 84% were cirrhosis of liver, 7% were chronic active hepatitis, 3% were chronic persistent hepatitis, 2% were Wilson's disease with cirrhosis and 4% were hepatocellular carcinoma (HCC) on the top of cirrhosis of liver. The peak age incidence was between 31-50 years with male-female ratio of 4.88:1. History of jaundice (42%), parenteral medications (14%), infusion (6%) and abdominal surgery (4.0%) were important findings from patient's past history. History of alcohol intake was found in only 4% cases. Overall, weakness (78%), anorexia (72%), abdominal swelling (74%), weight loss (64%), ankle swelling (42%), low grade fever (35%) and yellowish discolouration of eyes, skin and urine (37%) were the most common symptoms. Common signs, revealed by clinical examination as a whole, were anaemia (55%), ascites (68%), oedema (52%), jaundice (34%), palpable spleen (55%) and hepatic facies (37%). Cirrhosis of liver most commonly occurs in middle aged male patients. Weakness, weight loss, anorexia, abdominal discomfort/dyspepsia and swelling of the abdomen are the most prevalent symptoms.

2021 ◽  
Vol 2 (6) ◽  
pp. 10-14
Author(s):  
Gopen Kumar Kundu ◽  
Rumana Islam ◽  
Noor E-Sabah ◽  
ABM Mukib

Neurodegenerative diseases (NDD) are a heterogeneous group of disorders characterized by progressive loss of previously acquired skills that are of varied etiology, clinical manifestations, and natural course. There is a paucity of data on clinical profile of neurodegenerative diseases in our population. We conducted a retrospective study with 68 diagnosed cases of NDD at a tertiary care hospital in Bangladesh. Among them, more than one-third of children were in 1-5 years age group. The mean age was 10.2±3.1 year and male to female ratio was 2:1. Fifty percent of cases had a history of consanguineous parents. Leukodystrophy was most common (30.88%) among NDDs, followed by Wilson disease (26.47), SSPE (22.1%), and Degenerative Ataxia (20.59%). Motor skill regression was the most common presentation (97%), followed by speech regression in 91% and Gait disorder in 83% of children. Seizure was presenting features in 24% of children. Neuroimaging abnormalities were found in 80.88% NDD cases. Among them white matter hyper intensity in 29.41%, cerabeller atrophy in 13.25 %, and cerebral atropy in 11.76% of children. Eye changes were found in about two-thirds (69.12%) of cases of NDD. Among them, optic atrophy was found in 29.41%, and KF rings in 25.00% of cases.


2019 ◽  
Vol 6 (2) ◽  
pp. 106-110
Author(s):  
Md Enayet Ul Islam ◽  
Afzal Momin ◽  
Farzana Sharmin ◽  
Provat Kumar Sarkar ◽  
Md Azharul Hoque

Background: Parkinson’s disease occurs in different socio-demographic characteristic people. Objective: The Purpose of the present study was to see the socio-demographic characteristics of Parkinson’s disease patients attended at a tertiary care hospital in Dhaka city. Methodology: This cross-sectional study was carried out in the in-patient and out-patient Department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka from July 2012 to December 2013 for a period of one and half year. All patients with Parkinson’s disease who were admitted under department of Medicine and Neurology and also who visited out-patient department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka were taken as study population. Patients who were diagnosed as Parkinson’s disease according to Brain Bank clinical criteria for diagnosis of Parkinson’s disease were included in this study. The demographic and socio-economic characteristics were recorded in a semi-structured questionnaire. Result: A total number of 40 Parkinson’s patients were recruited for this study. The mean age was 69.15±10.08 years. The male female ratio was found 1.22:1. The majority patients were businessman which was 13(32.5%) cases. The majority of 15(37.5%) patients came from rural area. However, 12(30.0%) patients were in primary level. Furthermore, 21(52.5%) patients came from lower class. Conclusion: In conclusion elder male rural dwellers are mostly suffering from Parkinson’s disease Journal of Current and Advance Medical Research 2019;6(2):106-110


2018 ◽  
Vol 4 (1) ◽  
pp. 51-53 ◽  
Author(s):  
Md Mizanur Rahman ◽  
Md Mahfuzur Rahman ◽  
Md Abdullah Yusuf ◽  
AFM Arshedi Sattar ◽  
Md Ayub Ali ◽  
...  

Background: Traumatic thoraco-lumbar spine injuries occur in different ways during working.Objectives: The purpose of the present study was to find out the-demographic Characteristics and Mode of Traumatic Thoraco-Lumbar Spine Injuries.Methodology: This cross-sectional study was conducted at the National Institute of Traumatology and Orthopaedic Rehabilitation (NITOR), Dhaka, Bangladesh from July 2004 to June 2006 for a period of 2(two) years. Patients with diagnosed cases of traumatic thoraco-lumbar spinal injury with complete or incomplete cord lesion irrespective of sex were selected as study population. An elaborate history of the selected patient was taken with an emphasis of mechanism, time of injury, past history of illness.Result: A total number of 17 patients with thoracolumbar spine injury were recruited. Out of 17 patients, 7(41.2%) patients were in the age group of 21-30 years that is very younger age group. The mean age was 29.29 years. The male and female ratio was 4.7:1. In this series most affected people are farmer (47.05%). Most affected groups are injured by fall from height (70.58%) especially from tree and from roof of the buildings.Conclusion: Young age group male workers are most commonly affected in traumatic thoraco-lumbar spine injuries.Journal of National Institute of Neurosciences Bangladesh, 2018;4(1): 51-53


2020 ◽  
pp. 1-5
Author(s):  
Smita Mundada ◽  
Tejas Mandlecha ◽  
Prabha Khaire ◽  
Shilpa Pawar

Cerebral palsy has emerged as one of the major causes of childhood disability in India. In low and middle income countries there are gaps in knowledge in the spheres of epidemiological research, intervention and service utilization. AIMS AND OBJECTIVES: This study describes the clinical features associated problems of children with CP visiting a government tertiary care Hospital from Maharashtra, India. Materials and Methods: This was cross sectional retrospective observational study conducted on 78 children of cerebral palsy. Result: Among 78 enrolled children, maximum 50%(n=39) of children were between1-3yr age group with male to female ratio was 1.05:1. History of consanguinity was seen in 35.9% (n=28) subjects, 69.2%(n=54)of subjects were from the urban area. 78.2% (n=61) subjects were born term , 65.3%(n=51) cases had a history of NICU stay with the most common etiological factor being birth asphyxia seen in 38.4 %( n=30) subjects followed by sepsis in 29.5% subjects (n=23). Most common type of cerebral palsy was spastic 87.1% followed by dyskinetic 10.2%. Most of the participants were at GMFCS level IV and V (23.1% and 47.4% respectively). 78.2% subjects were having feeding problems, 43.6% had associated epilepsy. Majority of our subjects had Microcephaly (69.2%) and malnutrition (74.3%). MRI was done in only 34.6% of subjects with most common finding being periventricular white matter injury (PVWMI)). Conclusion: It is suggested that rehabilitation clinics should be set up for CP patients at every government medical college so that parents can be made aware of the disease, handicaps, prognosis, and management.


2020 ◽  
Vol 1 (1) ◽  
pp. 16-19
Author(s):  
Ritesh Luitel ◽  
Sujan Dhital ◽  
Subodh Sharma Paudel ◽  
Suman Bhattarai

Introduction: Incidence of stroke patients is increasing in low income countries like Nepal where management of these patients is challenging due to poor healthcare resources. Ischemic stroke is related to risk factors like age, male population, hypertension, diabetes mellitus, smoking and alcohol. Identification of these risk factors in the vulnerable population is important for prevention of ischemic stroke. The purpose of this study is to find out the social and demographic characteristics of patients with acute ischemic stroke treated at Upendra Devkota Memorial National Institute of Neurological and Allied Sciences, a tertiary care hospital of Nepal. Methods: Data was collected from all acute ischemic stroke patients presenting to the hospital over a period of one year. The age, sex, medical history of hypertension and diabetes and history of smoking and alcohol consumption were recorded. Statistical analysis of data was performed using Microsoft EXCEL 2019. Result: Total 310 patients were studied, out of which two-thirds were male. The highest number of patients were within the age group of 60-80 years with the mean age being 60 years. Hypertension and diabetes were present in 67.42% and 28.53% of patients respectively. 43.93% of the patients smoked while 33.87% of the patients consumed alcohol. Conclusion: Identification of association between risk factors like age, sex, hypertension, diabetes mellitus, smoking and alcohol consumption must be the emphasis for targeted preventive action to decrease the increasing burden of ischemic stroke among developing countries.


2021 ◽  
pp. 70-72
Author(s):  
Gaurav Santosh Nemade ◽  
Sumit Nitin Dhus ◽  
Arushi Ramesh Shetty ◽  
Neha Dhananjay Firake

BACKGROUND AND OBJECTIVES: The burden of tuberculosis (TB) in India is the highest accounting for 26% of the global incidence. A total of 1.4 million people died from TB in 2019 (including 208 000 people with HIV). India accounts for a fourth of the global burden of TB and 29% of global mortality. Therefore, we carried out this study to compare demographic, lifestyle and clinical characteristic between pulmonary TB (PTB) and extrapulmonary TB (EPTB). MATERIALS AND METHODOLOGY:Aretrospective analysis was carried of 348 patients diagnosed in DOTS centre, Pravara Rural Hospital, Loni. Characteristics of demographic and clinical characteristics were obtained from medical case records. RESULTS:Among the 348 cases, 71.3% were PTB and 28.7% were EPTB including, pleural (36%), meningeal (27%) and lymphatic (20%) cases. The male to female ratio in PTB and EPTB are 1.99 and 1.22 respectively. EPTB was more common at younger age (<25 years). Tobacco addiction (10.9%), diabetes mellitus (4.03%), HIV positivity (12.1%) and history of contact with Tb patients (17.7%) were more likely to be associated with PTB. CONCLUSION:Increased awareness of the risk factors may facilitate early case nding and better management outcomes for these patients.


2021 ◽  
Vol 15 (9) ◽  
pp. 2451-2453
Author(s):  
Shahid Iqbal ◽  
Muhammad Fareed Khan ◽  
Raja Imtiaz Ahmed ◽  
Shahab Saidullah ◽  
Nisar Ahmed ◽  
...  

Objective: To find out the pattern of CHD and associated risk factors among children presenting at a tertiary care hospital. Study Design: A case-control study. Place and Duration of the Study: The Department of Pediatrics and Department of Cardiology, Sheikh Khalifa Bin Zayed Al Nahyan Hospital, Rawlakot from July 2020 to June 2021. Material and Methods: A total of 207 children of both genders, screened by ECG along with chest x-ray and further confirmed with the diagnosis of CHD through echocardiography were enrolled as cases. Same number of healthy controls (n=207) were recruited from immunization center of the study institution. Among cases, types of CHD were noted. For cases and controls, demographic, antenatal and maternal risk factors including maternal age, gender of the child, history of consanguinity, history of febrile illness in pregnancy, use or multi-vitamin or folic acid in pregnancy, bad obstetrical history and maternal diabetes mellitus were noted. Results: In a total of 414 children (207 cases and 207 controls), there were 219 (53.8%) male. In terms of CHD types among cases, VSD was the most noted in 62 (30.0%), ASD 35 (16.9%), TOF 33 (15.9%) and PDA in 30 (14.5%). Cases were found to have significant association with younger age (78.3% cases below 1 year of age vs. 64.7% in controls, p=0.0085), bad obstetrical history (p=0.0002), history of febrile illness in 1st trimester of pregnancy (p=0.0229) and lack of multivitamins and folic acid in the 1st trimester of pregnancy (p=0.0147). Conclusion: Majority of the children with CHDs were male and aged below 1 year. VSD, ASD, TOF and PDA were the most frequent types of CHD. Younger age, bad obstetrical history, history of febrile illness in 1st trimester of pregnancy and lack of multivitamins and folic acid in the 1st trimester of pregnancy were found to have significant association with CHDs among children. Keywords: Congenital heart disease, echocardiography, ventricular septal defect.


2021 ◽  
Vol 7 (4) ◽  
pp. 315-319
Author(s):  
U Ketan Raju ◽  
Hanamant G Bobade ◽  
Anil Mishra

Dermatophytes are aerobic fungi that produce proteases that digest keratin and allows colonization, invasion and infection of the stratum corneum of the skin, the hair shaft, and the nail. This study was an attempt on the part of the author to find out the incidence and various clinico-epidemiological characteristics of Dermatophytosis in skin OPD of Tertiary care Hospital, B.K.L.W.R.M.C., Dervan. The study was carried on 2444 patients of Dermatophytosis attending the OPD, out of which 49.79% of the cases were Tinea Cruris (TC). The age group of 11-20 years showed maximum prevalence of Dermatophytosis (22.17%). 58% of the patients had diffuse lesions. Body involvement was seen in 87% of cases. Itching was the most common condition associated with Dermatophytosis. 35% of the patients reported with family history of Tinea Cruris.Circumscribed variety of TC was found to be most common variant mostly observed in 2and 4 decade, with a male preponderance. Groin was the most common site with multiple lesions. Nail changes was most commonly associated with TC.


2021 ◽  
Vol 8 (4) ◽  
pp. 308-312
Author(s):  
Pendru Raghunath ◽  
LN Rao Sadanand

Streptococci are gram positive cocci arranged in chains and are part of normal flora of humans and animals. The present study is carried out to determine the prevalence and risk factors for the carriage of beta-haemolytic streptococci (BHS) among women visiting Dr. VRK Women’s Teaching Hospital & Research Centre, Hyderabad. Vaginal swabs were collected from 250 patients attending outpatient department (OPD) of Dr. VRK Women’s Teaching hospital. Swabs were inoculated onto 5% sheep blood agar plates and incubated for 24 h at 37°C in a candle jar. BHS isolates were phenotypically identified by standard microbiological techniques, all the isolates presumptively identified as BHS were tested for Bacitracin susceptibility. Sensitive isolates were presumptively identified as GAS and resistant isolates were identified as non-group A BHS (NGABHS). Presumptively identified GAS & NGABHS isolates were serogrouped by Lancefield grouping using a commercially available latex agglutination test. BHS were isolated from 12.4% of samples. As many as 12 BHS isolates were identified as GAS and 19 were identified as NGABHS. Ten of nineteen were identified as group B (GBS), 4 (12.9%) were identified as group C (GCS) and 5 (16.12%) were identified as group G (GGS). Among six clinical groups, the prevalence of GAS is highest i.e. 7.5% in female patients visiting Gynaecology OPD with history of white discharge. Prevalence of NGABHS was more among post insertion (18%) IUCD group compared to pre insertion (8%) IUCD group. GBS were isolated from 7% of samples from IUCD group and 4% of samples from prostitutes.This study reports the prevalence of BHS among women visiting a tertiary care hospital in Hyderabad. This study also identified certain risk factors such as IUCD usage and working as a FSW are associated with the increased prevalence of NGABHS especially GBS.


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