scholarly journals Comparison between two Fluid Management Techniques of Ringer lactate and Hydroxyethyl Starches in cases of Burn

2020 ◽  
Vol 11 (3) ◽  
pp. 13-16
Keyword(s):  
Hospital Stay ◽  
Urine Output ◽  
Fluid Management ◽  
The Body ◽  
Fluid Replacement ◽  
Ringer Lactate ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Hydroxyethyl Starches

Background: Fluid replacement is one of the important issues in the management of burn cases. Objective: To compare the outcome between Ringer lactate and Hydroxyethyl starches (HESs) in cases with burn injuries. Methodology: Study design: Randomized controlled trial. Place and duration of study: Department of Plastic Surgery, Sheikh Zayed Hospital, Rahim Yar Khan, from June to December 2018. Study subjects selected were those who had a burn of any type (thermal, chemical, electric) and at least more than 10% of the surface area of the body. The cases were then divided into two equal groups. The fluid requirement was calculated according to the Parkland formula. After this, the cases in group A were given Ringers lactate solution 500 ml while those in group B were given 500 ml of 6% hydroxyethyl starches (HESs) and further fluid was administered in group A as ringer only and in group B as ringer and HES in a ration of 2:1. The cases were then followed to look for various outcomes in the form of urine output, serum creatinine, and mean hospital stay. Results: In this study, there were a total of 60 cases (30 in each group). The mean age in group A and B was 17.33±5.39 vs 19.11±4.79 years (p= 0.33). Mean hospital stay was 14.65±3.31 vs 13.49±2.78 days with p= 0.41. Mean urine output per day was 1645.81±143.47 vs 1705.31±165.83 ml with p= 0.43 and mean creatinine in group A and B was 1.79±0.38 vs 1.83±0.44 with p= 0.86. Conclusion: There was no significant difference in both the groups regarding urine output, creatinine, and mean hospital stay.

scholarly journals Biochemical and Haemodynamic Effects of Crystalloid Solutions Administered During Perioperative Period

2009 ◽  
pp. 33-37
Author(s):  
Debasish Banik ◽  
Qumrul Huda ◽  
Abdul Hye ◽  
KM Iqbal
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Pulse Rate ◽  
Normal Saline ◽  
Urine Output ◽  
Perioperative Period ◽  
The Body ◽  
Post Operative Period ◽  
Significant Difference ◽  
Group A

Forty five (45) ASA grade I & II patients aged between 21 to 55 years, scheduled for electiv abdominal surgery (incision not exceeding 15 cm with minimal blood loss, under general anaesthesia were randomly allocated into three groups (A, and C). Patients of Group A, B and C received infusion of 5% dextrose aqua, normal saline and 5% dextrose in normal saline respectively throughout perioperative course (upto 24 hours after operation). Each group received post operative period. Parameters recorded were mean arterial pressure (MAP), Pulse, Serum elecirolyte (Na+, K+), amount of fluid in fused and urine output during operation and postoperatively Blood samples for serum electrolyte estimation were taken just before induction, immediately before reversal and twenty four hours after surgery. A standard anaesthetic technique was followed for all groups.Percentage increase from pre-operative values were calculated for mean arterial pressure, pulse rate and serum electrolytes. The ratio between urine output and fluid infused during per- and post-operative period were calculated. There were statistically significant (p<0.05) difference between group A and C in perand post-operative change in pulse rate and statistically significant difference (p<0.05) in postoperative output/input ratio between group A and B and highly significant (p<0.01) between A and C. Electrolyte containing fluids of higher osmolality caused increased diuresis in per-operative period and increased pulse rate in post-operative period. So, although there are few difference between three fluids, these didnot produce any effects( beneficial or detrimental) on the body system under normal conditions. Journal of BSA, Vol. 19, No. 1 & 2, 2006 p.33-37

Clinical Results Of A Lamina With Spinous Process And An Iliac Graft As Bone Grafts In The Surgical Treatment Of Single-Segment Lumbar Pyogenic Discitis: A Retrospective Cohort Study

2020 ◽  
Author(s):  
Weiyang Zhong ◽  
Xinjie Liang ◽  
Xiaolin Wang ◽  
Ke Tang ◽  
Tianji Huang ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Spinous Process ◽  
Bone Grafts ◽  
Clinical Results ◽  
Single Segment ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Segmental Angle

Abstract Background: A retrospective study investigated and compared the results of a lamina withspinous process (LSP) and an iliac graft (IG) as bone grafts in single-segment lumbar pyogenic discitis (LPD) through one-stage-posterior-only approach with radical debridement and internal instrumentation.Methods: Data from 37 patients were reviewed. A LSP was placed in 17 patients (group A), and an IG was implemented in 20 patients (group B). The surgery time, surgery hemorrhage, hospital stay, drainage, and follow-up (FU) were reviewed. The visual analogue scale (VAS), Oswestry Disability Index (ODI), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level, segmental angle, intervertebral height and bony fusion time were compared preoperatively and at the final FU.Results: All patients were followed-up for a mean of 27.94±2.35 months in group A and 30.29±1.89 months in group B, without a difference. The mean age was younger in group A than in group B (P<0.05). The surgery time, surgery hemorrhage, and hospitalization cost were lower in group A than in group B (P<0.05), except for the hospital stay and drainage time. Fever occurred in 10 patients in group A and 12 patients in group B. The ESR, CRP level, and VAS and ODI scores were significantly decreased, and there were no significant differences between the groups at the final FU. The distribution of bacterial agents in blood culture was 1 case of Aerobacter cloacae, 2 of Staphylococcus aureus, 2 of Escherichia coli, and 1 of Streptococcus viridis in group A and 1 of S. aureus，1 of Staphylococcus warneri and 2 of Klebsiella pneumoniae in group B. Pyogenic infection was observed in the pathological findings of all patients. No significant difference was found in the mean segmental angle or mean intervertebral height preoperation and at the final FU between the groups.Conclusion: The use of LSP as a new bone graft is reliable, safe, and effective for surgical management for the LPD while surgery is proposed as a good management strategy for LPD in carefully selected patients.

scholarly journals PREVALENCE OF HEPATIC STEATOSIS AMONG CHILDREN AND ADOLESCENTS WITH CYSTIC FIBROSIS AND ITS ASSOCIATION WITH NUTRITIONAL STATUS

2019 ◽  
Vol 37 (4) ◽  
pp. 435-441
Author(s):  
Amanda Oliva Gobato ◽  
Ana Carolina Junqueira Vasques ◽  
Antonio Fernando Ribeiro ◽  
Roberto Massao Yamada ◽  
Gabriel Hessel
Keyword(s):  
Cystic Fibrosis ◽  
Nutritional Status ◽  
Children And Adolescents ◽  
Hepatic Steatosis ◽  
Statistical Tests ◽  
The Body ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B

ABSTRACT Objective: To determine the prevalence of hepatic steatosis (HS) in children and adolescents with cystic fibrosis (CF) and associate it with nutritional status. Methods: Cross-sectional study with children and adolescents with CF diagnosis. Weight and height were used to calculate the body mass index (BMI) and subsequent classification of the nutritional status. The midarm circumference (MAC), triceps skinfold thickness (TSF) and midarm muscle circumference (MAMC) were used to evaluate body composition. Abdominal ultrasonography was performed for diagnosis of HS. The statistical tests used were Student’s t test, Mann-Whitney test and chi-square test with significance level of 5%. Results: 50 patients with CF were evaluated, 18 (36%) were diagnosed with HS (Group A) and 32 (64%) without HS (Group B). The mean age of Group A was 13,2±4,9 years old and Group B 11,7±4,9; for BMI, the value for Group A was 18,0±4,1 and Group B was 15,7±3,8; the TSF of Group A was 8,4±3,5 mm and Group B was 7,0±2,5 mm. For these variables, there was no significant difference between the groups. The mean of MAC and MAMC differed significantly between the groups, being higher in the HS group, with p values of 0,047 and 0,043. Conclusions: The frequency of HS in patients with CF is high and it is not related to malnutrition, according to the parameters of BMI, TSF and MAMC. The values of MAC and MAMC indicated a greater reserve of muscle mass in patients with HS.

scholarly journals Comparative Study of Efficiency between Povidone Iodine and Normal Saline Lavage in the Treatment of Acute Peritonitis

2018 ◽  
Vol 4 (1) ◽  
pp. 15-20
Author(s):  
Haridas Saha ◽  
Mohammad Ibrahim Khalil ◽  
Aminul Islam ◽  
Abdullah Al Mamun ◽  
Md Margub Hossain
Keyword(s):  
Hospital Stay ◽  
Wound Infection ◽  
Normal Saline ◽  
Povidone Iodine ◽  
Medical College ◽  
Acute Peritonitis ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Saline Lavage

Background: Control of the primary site of sepsis is the main determinant of good surgical outcome. Objective: The purpose of the present study was to compare the efficiency between povidone iodine and normal saline lavage in the treatment of acute peritonitis. Methodology: This was a randomized clinical trial conducted in the Department of Surgery at Dhaka Medical College & Hospital, Dhaka, Bangladesh. Patients with acute peritonitis due to gastrointestinal causes who were admitted in the different units of Dhaka Medical College Hospital during the study period were selected as study population. Among them patients who were treated with povidone iodine were enrolled in the present study in group A and patients who were treated with conventional normal saline were in group B. Results: A total number of 1050 patients were recruited for this study. Among them 100 patients were enrolled in the present study of which group A (50 patients) for povidone iodine and group B (50 patients) for conventional normal saline. On 7th POD wound infection was found in Group A and Group B were 11(22.4%) and 21(44.7%) respectively. Statistically significant difference in post operative complication of wound infection was observed on 7th POD between the groups (p<0.05). Post operative hospital stay in Group A and Group B were 11.50 ± 4.48 and 13.46 ± 5.13 days respectively. There is statistically significant difference in post operative hospital stay between the groups (p<0.05). Conclusion: Statistically significant difference observed in post operative complication of wound infection and burst abdomen on 7th POD between the groups. The present study there is statistically significant difference in post operative hospital stay between the groups also observed. Bangladesh Journal of Infectious Diseases 2017;4(1):15-20

Alvimopan as an essential component of ERAS protocol to decrease length of hospital stay.

2020 ◽  
Vol 38 (6_suppl) ◽  
pp. 517-517
Author(s):  
Peter Hanna ◽  
Arveen Kalapara ◽  
Subodh Regmi ◽  
Kalyana Srujana ◽  
Joseph Zabell ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Hospital Stay ◽  
Radical Cystectomy ◽  
Smoking Status ◽  
Length Of Hospital Stay ◽  
Significant Difference ◽  
Bowel Movements ◽  
Group A ◽  
Group B ◽  
Eras Protocol

517 Background: Radical cystectomy for muscle invasive bladder cancer is the gold standard. However, it is frequently associated with a prolonged length of hospital stay (LOS). We study the effect of ERAS protocol implementations and Alvimopan use in patients undergoing radical cystectomy and its impact on length of hospital stay (LOS). Methods: Retrospective cohort study involving consecutive patients undergoing radical cystectomy for bladder cancer at our institution from 2010 through 2018. We evaluated Alvimopan use plus an ERAS protocol post radical cystectomy versus patients who underwent ERAS protocol alone versus those who were managed prior to ERAS protocol implementation. Primary outcome of interest was LOS, controlling for age, sex, smoking status and Charleson comorbidities index. Results: 146 patients (49.32 %) received standard care (non-ERAS) (group A), 102 patients (34.45 %) underwent ERAS protocol alone (group B) and 47 patients (15.87 %) underwent ERAS protocol plus Alvimopan (group C). There was no significant difference in length of stay between group A and group B (p=0.856). However, group C experienced a shorter LOS (16.6%) compared to group A (p=0.015). Similarly, group B was not significantly associated with the days to bowel movements compared to group A (p=0.112), however, group C demonstrated a significantly shorter time (16.3%) to bowel movements compared to group A (p=0.015). On other hand, group c wasn’t significantly associated with time tolerance to regular diet (p=0.068). Limitations include retrospective nature of some of the data, non-randomized approach and confounders such as a mix of robot and open approaches to cystectomy. Conclusions: Of all ERAS protocol components, Alvimopan appeared to be the most significant contributor in accelerating GI recovery and decrease LOS in our cohort.

scholarly journals Effects of growth promoter and multivitamin-mineral premix supplementation on body weight gain in broiler chickens

2013 ◽  
Vol 10 (2) ◽  
pp. 245-248 ◽  
Author(s):  
MA Rahman ◽  
MS Parvin ◽  
RR Sarker ◽  
MT Islam
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
The Body ◽  
Growth Promoter ◽  
Commercial Feed ◽  
Significant Difference ◽  
Group A ◽  
Group B

An experiment was conducted at the Khanpura Poultry Farm, near to the Babugonj campus of Patuakhali Science and Technology University, Patuakhali during the period from August to September, 2011 to evaluate the effect of growth promoter and multivitamin-mineral premix on the body weight gain in broiler chickens. A total of 90 ‘Cobb 500’ day-old broiler chickens were randomly divided into three equal groups (n = 30), namely Groups A, B and C. Broiler birds in groups A and B were supplemented with growth promoter and multivitamin-mineral premix, respectively in addition to commercial feed from day 4 till day 25. The dose of both the growth promoter and multivitamin-mineral premix was 2.5 g/kg of feed. Chickens of group C served as control and supplemented with commercial feed only. Body weight was recorded at three times as on day 11, 18 and 25, respectively. The mean body weight was insignificantly (p > 0.05) higher in birds of groups A (992.5±139.6g) and B (978.3±147.0g) than those of group C (926.7±133.2g). The percent increase in body weight gain compare to control was increased in both the supplemented groups (5.8% in group A and 8.8% in group B) though there was no significant difference. Based on the results, it is suggested that supplementation of growth promoter and multivitamin-mineral premix in broilers even after feeding of commercial feed has positive effect on the growth of broilers.DOI: http://dx.doi.org/10.3329/jbau.v10i2.14914 J. Bangladesh Agril. Univ. 10(2): 245-248, 2012

scholarly journals Outcome of thyroid lobectomies undergone with and without drains

2020 ◽  
Vol 8 (8) ◽  
pp. 2919
Author(s):  
Sahrish Bachani ◽  
Shahid N. Memon ◽  
Muhammad R. Pathan ◽  
Rehmat Sehrish Shah ◽  
Aneeta Kumari ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Wound Infection ◽  
Pain Score ◽  
Thyroid Nodules ◽  
University Hospital ◽  
P Value ◽  
Thyroid Lobectomy ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Thyroid lobectomy is a common operative technique of management of benign solitary thyroid nodules in which drains are used routinely. Objective of this study to compare the outcome of thyroid lobectomies undergone with and without drains in patients of benign solitary thyroid nodules.Methods: A comparative cross-sectional research was completed on 98 patients of benign solitary thyroid nodules at surgery department of Liaquat University Hospital Jamshoro. Patients having age of 18-60 years underwent thyroid lobectomies were included and distributed in two groups A and B. Group A includes thyroid lobectomies with drain and Group B without drain. Postoperative outcomes including pain score assessed via visual analog score (VAS), hospital stay and complications including wound infection, seroma and hematoma.Results: Out of 98 cases, 49 underwent thyroid lobectomy with drain and 49 without a drain. Females patients were in majority in group A 42 (85.7%) and also in group B 47 (95.9%). No significant difference (p-value=0.674) was in mean age of group A 30.8±10.2 years and group B 31.8±12.2 years. Higher mean with significant difference (p-value=0.001) was in pain score of group A 5.61±1.25 as compared to group B 3.55±0.70. No significant difference was in complications; seroma 1 (2.04%) vs 5 (10.20%), hematoma 1 (2.04%) vs 1 (2.04%) and infection 3 (6.12%) vs 0 (0.0%) in group A and B respectively. Higher mean with significant difference (p-value=0.001) was in hospital stay of group A 2.40±1.57 days as compared to group B 1.42±0.54 days. No significant difference (p-value=0.748) was in overall rate of complications in group A 5 (10.20%) and B 6 (12.24%).Conclusions: Thyroid lobectomy with drain is not effective in lowering the postoperative complications whereas enhanced the risk of postoperative pain, wound infection and duration of hospital stay as compared to thyroid lobectomy without a drain.

scholarly journals Effects of Ringer Lactate Normal Saline Combination Vs Normal Saline during Renal Transplantation Surgery on Early Postoperative Outcome

2019 ◽  
Author(s):  
Pejman Pourfakhr ◽  
Alireza Sohrabi Nodehi ◽  
Hamid Reza Shariefnia ◽  
Mohammad Reza Khajavi
Keyword(s):  
Renal Transplantation ◽  
Normal Saline ◽  
Urine Output ◽  
Postoperative Outcome ◽  
Fluid Replacement ◽  
Kidney Transplant Recipients ◽  
Ringer Lactate ◽  
Serum Chloride ◽  
Significant Difference ◽  
Kidney Transplantations

Background: Traditionally normal saline is the most common crystalloid solution that is used in transplant surgery. Normal saline (NS) because of the higher risk of acidosis and higher levels of serum chloride may have more deleterious effects in kidney transplant recipients Thus; the aim of this study was to determine the safety of ringer lactate normal saline combination if used during a renal transplant. Methods: One Hundred adults undergoing kidney transplantations were enrolled in a double-blinded randomized prospective clinical trial. They were divided into two groups in order to receive RL& NS and NS infusion as intraoperative IV fluid replacement therapy. All patients received 40 ml/kg fluid during surgery. Serum chloride, sodium, Cr and BUN were checked before operation and 6hour after surgery. Urine output BUN and Cr was also checked in 1, 3 and 7 day after surgery. At the end of surgery, we corrected the acid base status with bicarbonate according to base excess< -15 or PH<7.15 if needed in both groups. Results: There was a significant difference in the serum chloride level (p= 0.001) and urine output (p= 0.003) between the two groups at the 6 hours after transplantations. Postoperative BUN and Cr level at 2,3 and 7 days in RL&NS group was significantly lower than group of NS (P= 0.011). Also, urine output during this study time was significantly higher in RL&NS group (p=0.001). Conclusion: Combination of Ringer lactate &normal saline crystalloid solutions are associated with higher urinary output and most favorited out come in the early post-operative days after renal transplantation surgeries.

scholarly journals Effects of Moringa oleifera on the developing cerebrum of young wistar rats

1970 ◽  
Vol 8 (1) ◽  
Author(s):  
A Z Abijo ◽  
O O Adeeyo ◽  
O A Komolafe ◽  
O S Saka ◽  
V K Abodunrin
Keyword(s):  
Frontal Cortex ◽  
Wistar Rats ◽  
Moringa Oleifera ◽  
The Body ◽  
Brain Weight ◽  
Control Group ◽  
Significant Difference ◽  
Group A ◽  
High Doses ◽  
Group B

The study evaluated the effects of moringa oleifeira on the histoarchitecture of the cerebral cortex, the body weight and brain weight of young wistar rats. Fifteen (15) young wistar rats of both sexes weighing 20-30g were used for this study. They were randomly assigned into three groups (A, B and C) of five rats each. Group A served as control and received distilled water, group B and C received 100 mg/kg and 200mg/kg of moringa oleifera respectively. Treatment lasted for a period of 6 weeks (orally). Rats were weighed and sacrificed under ketamine (30 mg/kg) anaesthesia. The cerebrum was harvested and fixed immediately in 10% formolcalcium, for further histological processing. One-way ANOVA was used to analyze data, followed by Newan-Keuls (SNK) for multiple comparisons. The results showed that there was significant increase in the feed intake of animals in groups B and C starting from the 4th week of administration. There was no significant difference in the relative brain weight and the mean weight of the rats in group B and C when compared with group A. Histological findings revealed that there was slight distortion in group B and more distortion in group C when compared with the normal histoarchitecture in control group A. The results obtained from this study showed that high doses of Moringa oleifera caused damage of some parts of histoarchitecture of the frontal cortex of developing wistarKey words: MORINGA OLEIFERA; Cerebrum; Frontal Cortex

Does Priming Implementation with Low-dose Albumin Reduce Postoperative Bleeding following Cardiopulmonary Bypass?

2003 ◽  
Vol 26 (3) ◽  
pp. 211-216 ◽  
Author(s):  
F. Onorati ◽  
G. Santarpino ◽  
A. Renzulli ◽  
M. De Feo ◽  
L.S. De Santo ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Low Dose ◽  
Postoperative Bleeding ◽  
Ringer Lactate ◽  
Versus Group ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Lactate Solution

This study aimed to assess whether low doses of albumin in the priming solution for cardiopulmonary bypass (CPB) reduce postoperative bleeding. Three-hundred and seventy-seven patients undergoing CPB were retrospectively assigned to group A (154 patients, CPB primed with 20 ml/kg Ringer Lactate solution + 0.75mg/kg albumin 20%) and group B (223 patients with 20 ml/kg Ringer Lactate). A significant difference was found in terms of reoperations for bleeding (group A 0/154 versus group B 9/223; P=0.033). The mean number of blood derivatives transfused per patient was higher in group B than in group A (p <0.001). Platelet count after CPB was higher in group A than in group B (175±52×103/μl versus 131±70×103/μl; P=0.045). The amount of postoperative bleeding was 525ml versus 680ml at 24hrs (p <0.001), 819ml versus 1102ml at 48hrs, (p <0.001), 963ml versus 1294ml at 72hrs, (p <0.045) (group A versus group B respectively). Crystalloid priming with low-dose albumin reduces postoperative bleeding.

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