Effect of Revive Capsule on Cardiovascular Risk Indices in Male Albino Rats in Relation to the Duration of Administration

Background: Hormonal contraceptives (HCs) have been successfully used worldwide to prevent pregnancy by inhibiting ovulation and implantation. These contraceptives have effects on lipid metabolism, body fat and blood pressure which are all risk factors for cardio vascular disease (CVD). Some studies have reported that prolonged use of these hormone-based contraceptives have negative effect on cardiovascular risk indices, however, few of such studies have been done in Ghana, hence this study sought to examine the effect of various forms of contraceptives on cardio vascular risk indices in the Volta Region of Ghana.Methods: Purposive random sampling was employed in selecting women on various forms of contraceptives and aged-matched controls into the study. Fasting blood sample was collected from each participant after overnight fast for 10-16 hours into plain tubes and the sera used to determine lipid profile. Socio-demographic and BMI variables were also analyzed in this case-control study.Results: Statistically significant differences were observed for Diastolic Blood Pressure (DBP) (p=0.0153), High Density Lipoprotein levels (HDL) (p=0.001), and the atherogenic index (p=0.0101) between the cases and the controls.Conclusions: The use of HC significantly affects the DBP, HDL and atherogenic index and these could pose substantial risk for the development of CVD.

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Subclinical Atherosclerosis in Systemic Sclerosis: Not Less Frequent Than Rheumatoid Arthritis and Not Detected With Cardiovascular Risk Indices

Arthritis Care & Research ◽

10.1002/acr.22852 ◽

2016 ◽

Vol 68 (10) ◽

pp. 1538-1546 ◽

Cited By ~ 11

Author(s):

Gulsen Ozen ◽

Nevsun Inanc ◽

Ali U. Unal ◽

Fatmanur Korkmaz ◽

Murat Sunbul ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Cardiovascular Risk ◽

Systemic Sclerosis ◽

Subclinical Atherosclerosis ◽

Risk Indices

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Correlation between association of hypothyroidism and cardiovascular risk indices

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20182136 ◽

2018 ◽

Vol 5 (3) ◽

pp. 754

Author(s):

Rajendra Datt Mathur ◽

Rameshwar Prasad Gupta ◽

Deepak Gupta ◽

Reenika Mathur ◽

Ajay Kumar Bhargav

Keyword(s):

Risk Factors ◽

Cardiovascular Disease ◽

Cardiovascular Risk ◽

Total Cholesterol ◽

Hormone Level ◽

Lipid Level ◽

Clinical History ◽

Lipid Levels ◽

Medical College ◽

Risk Indices

Background: Association of hypothyroidism and cardiovascular diseases are important in development of Atherosclerosis. Hypothyroidism and sub clinical hypothyroidism reported highly risk factors due to lipid levels dearranged. Present study to demonstre of correlation of hypothyroidism and cardiovascular disease.Methods: The present study has carried out in the department of medicine and Biochemistry SRG Hospital and associated hospital, Jhalawar Medical College Jhalawar (Raj.) Total 100 Hypothyroidism cases and 100 euthyroidism subject were included in the study Information regarding clinical history were recorded in self Constructed present questionnaires Patients were examined and estimated TSH, T3, T4 total Cholesterol, LDLc, HDCc, TG data were analyzed by SPPS version 20.0.Results: Present study demonstrated increased levels of total cholesterol, LDH, VLDLC and TG and decreased level of HDLC and increased TSH level and decreased T3 and T4 Level in hypothyroidism cases when compared with euthyroid cases It was found significant.Conclusions: In present study hypothyroidism and hormone Level (TSH, T3, T4) and lipid level dearranged values are associated with development cardiovascular disease atherosclerosis.

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