scholarly journals Pravne, socijalne i etičke implikacije editovanja humanog genoma primenom tehnologije CRISPR/Cas9

2021 ◽  
Vol 69 (3) ◽  
pp. 625-645
Author(s):  
Ranko Sovilj ◽  
Sanja Stojković Zlatanović
Keyword(s):  
Low Cost ◽  
Holistic Approach ◽  
Human Medicine ◽  
Ethical Values ◽  
Social Significance ◽  
Ethical Justification ◽  
Core Subject ◽  
Genetic Interventions ◽  
The Impact ◽  
Critical Consideration

Discovery of CRISPR/Cas9 technology produced a revolution in human medicine, because of the availability, efficiency and low cost, which has raised a number of questions. Given that by applying CRISPR/Cas9 technology we can program our future children and extend their life expectancy, question is whether we should allow it. The point of the paper is to determine the limits of legal admissibility and ethical justification of this procedure, considering contemporary legal theoretical views, ethical values and social significance. Using normative, comparative and sociological method the authors analyze the impact of biotechnology development, in the context of genetic interventions, on redefining the regulatory framework. Critical consideration in the context of legal standardization of human genetic interventions and meeting the interests of all participants, has been identified as a core subject of research, which will be considered in accordance with a holistic approach to the realization of human rights.

scholarly journals We motif of social violence in the space of cinematic communication

2021 ◽  
Vol 27 (3) ◽  
pp. 167-186
Author(s):  
К. A. Tarasov
Keyword(s):  
Negative Impact ◽  
Low Cost ◽  
Public Concern ◽  
Social Significance ◽  
Social Violence ◽  
The Public ◽  
The Status ◽  
Cultural Code ◽  
Russian Cinema ◽  
The Impact

Social violence traditionally has been a constituent in the information flow of artistic communication, of the cinematic one especially. With the language specific to cinema it is easier, than with the languages of other arts, to attract and command the attention of a broad public with the spectacle of violence. Also, as a rule, it is more economical because of the relatively low cost of embodying violence on the screen considering the overall expensiveness of film production. In the West, the filming of practices of violence aimed at entertaining the public, as well as the public concern at the possibility of their negative impact on the rising generation, has a long history. Within the concept of “the audience as the victim” there were thousands of studies conducted, especially in USA. In the USSR cinema of the entertainment orientation was under the ideological ban which put the representation of violence within certain boundaries. In the 1990s the situation of cinema changed drastically. Je escalation of entertainment violence on the screen caused a public concern. Sociologists began to study its perception by and impact on spectators. In this regard, the article considers the experience of conceptualizing the reformatting of its representation after, consequent upon the impact of the last century’s revolutionary violence, cinema had obtained the status of “the most important of all the arts” and “the social significance” of the violence became the cultural code of its representation. But with the transition of Russian cinema to the market, foreign entertainment movies were granted open access to the nation’s film screens. Entertainment violence reached the status of a commercially important communicative attraction. Its effectiveness in this function is viewed in the article based on the materials of sociological surveys conducted among filmgoers of the cities of Kirov and Ekaterinburg. Another side of the issue considered as well is the sociocultural effects of violent images on the rising generation in whose midst there is a “risk group” that merits careful research and preventive acknowledgment in the process of social control.

Computer simulation study about the dependence of amorphous silicon photonic waveguides efficiency on the material quality

2020 ◽  
Vol 90 (3) ◽  
pp. 30502
Author(s):  
Alessandro Fantoni ◽  
João Costa ◽  
Paulo Lourenço ◽  
Manuela Vieira
Keyword(s):  
Amorphous Silicon ◽  
High Throughput Screening ◽  
Simulation Analysis ◽  
Low Cost ◽  
Deposition Process ◽  
Large Area ◽  
Sidewall Roughness ◽  
Sensing Applications ◽  
Fabrication Defects ◽  
The Impact

Amorphous silicon PECVD photonic integrated devices are promising candidates for low cost sensing applications. This manuscript reports a simulation analysis about the impact on the overall efficiency caused by the lithography imperfections in the deposition process. The tolerance to the fabrication defects of a photonic sensor based on surface plasmonic resonance is analysed. The simulations are performed with FDTD and BPM algorithms. The device is a plasmonic interferometer composed by an a-Si:H waveguide covered by a thin gold layer. The sensing analysis is performed by equally splitting the input light into two arms, allowing the sensor to be calibrated by its reference arm. Two different 1 × 2 power splitter configurations are presented: a directional coupler and a multimode interference splitter. The waveguide sidewall roughness is considered as the major negative effect caused by deposition imperfections. The simulation results show that plasmonic effects can be excited in the interferometric waveguide structure, allowing a sensing device with enough sensitivity to support the functioning of a bio sensor for high throughput screening. In addition, the good tolerance to the waveguide wall roughness, points out the PECVD deposition technique as reliable method for the overall sensor system to be produced in a low-cost system. The large area deposition of photonics structures, allowed by the PECVD method, can be explored to design a multiplexed system for analysis of multiple biomarkers to further increase the tolerance to fabrication defects.

Advancing dairy farming profitability through research

2001 ◽  
pp. 17-22
Author(s):  
J.R. Caradus ◽  
D.A. Clark
Keyword(s):  
Research And Development ◽  
Dairy Cow ◽  
Low Cost ◽  
Pasture Management ◽  
Nitrogen Fertiliser ◽  
Grass Endophyte ◽  
Forage Species ◽  
Development Outcomes ◽  
Dairy Cow Nutrition ◽  
The Impact

The New Zealand dairy industry recognises that to remain competitive it must continue to invest in research and development. Outcomes from research have ensured year-round provision of low-cost feed from pasture while improving productivity. Some of these advances, discussed in this paper, include the use of white clover in pasture, understanding the impacts of grass endophyte, improved dairy cow nutrition, the use of alternative forage species and nitrogen fertiliser to improve productivity, demonstration of the impact of days-in-milk on profitability, and the use of feed budgeting and appropriate pasture management. Keywords: dairy, profitability, research and development

Motivating Compliance: Firm Response to Mandatory Disclosure Policies

2018 ◽  
Vol 32 (2) ◽  
pp. 103-119
Author(s):  
Colleen M. Boland ◽  
Chris E. Hogan ◽  
Marilyn F. Johnson
Keyword(s):  
Conflict Of Interest ◽  
Low Cost ◽  
Cost Effective ◽  
Data Availability ◽  
Policy Adoption ◽  
Future Research ◽  
Regulated Firms ◽  
Firm Response ◽  
Disclosure Rules ◽  
The Impact

SYNOPSIS Mandatory existence disclosure rules require an organization to disclose a policy's existence, but not its content. We examine policy adoption frequencies in the year immediately after the IRS required mandatory existence disclosure by nonprofits of various governance policies. We also examine adoption frequencies in the year of the subsequent change from mandatory existence disclosure to a disclose-and-explain regime that required supplemental disclosures about the content and implementation of conflict of interest policies. Our results suggest that in areas where there is unclear regulatory authority, mandatory existence disclosure is an effective and low cost regulatory device for encouraging the adoption of policies desired by regulators, provided those policies are cost-effective for regulated firms to implement. In addition, we find that disclose-and-explain regulatory regimes provide stronger incentives for policy adoption than do mandatory existence disclosure regimes and also discourage “check the box” behavior. Future research should examine the impact of mandatory existence disclosure rules in the year that the regulation is implemented. Data Availability: Data are available from sources cited in the text.

scholarly journals Impacts of COVID-19 on Animals in Zoos: A Longitudinal Multi-Species Analysis

2021 ◽  
Vol 2 (2) ◽  
pp. 130-145
Author(s):  
Ellen Williams ◽  
Anne Carter ◽  
Jessica Rendle ◽  
Samantha J. Ward
Keyword(s):  
Holistic Approach ◽  
Physiological Measures ◽  
Environmental Interactions ◽  
Species Analysis ◽  
Zoo Animals ◽  
Animal Interaction ◽  
Chinese Goral ◽  
Grevy’S Zebra ◽  
The Impact ◽  
Swamp Wallaby

Prolonged and repetitive COVID-19 facility closures have led to an abrupt cessation of visitors within UK and Irish zoos for variable periods since March 2020. This study sought to increase understanding of the impact of closures and reopenings on animal behaviour, thereby broadening understanding of whether zoo animals habituate to visitors. Data were collected from June to August 2020 at two UK facilities on eight species (n = 1 Chinese goral, n = 2 Grevy’s zebra, n = 11 swamp wallaby, n = 2 Rothschild’s giraffe, n = 2 nyala, n = 4 Chapman’s zebra, n = 2 snow leopard and n = 3 Amur leopard). Behaviour change and enclosure use was variable across species but most changes were non-significant. Grevy’s zebra engaged in more comfort behaviour during closure periods than post-closure (p < 0.05). Chinese goral engaged in more environmental interactions during closure periods (p < 0.05). Grevy’s zebra spent longer than would be expected by chance closest to public viewing areas during closure periods (p < 0.008). These results suggest variable impacts of covid-19 closures and reopenings, mirroring human-animal interaction literature. We highlight the potential for some species to take longer to re-habituate to the presence of zoo visitors. As facility closures/reopenings are ongoing, we advocate a longitudinal monitoring approach. Furthermore, we recommend incorporation of physical and physiological measures of welfare where possible, alongside behavioural responses, to enable a holistic approach to answering fundamental questions on whether zoo animals habituate to visitors.

scholarly journals Ears in the Sky: Potential of Drones for the Bioacoustic Monitoring of Birds and Bats

Drones ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 9
Author(s):  
Adrien Michez ◽  
Stéphane Broset ◽  
Philippe Lejeune
Keyword(s):  
Forest Canopy ◽  
Low Cost ◽  
Population Monitoring ◽  
Biodiversity Loss ◽  
Active Species ◽  
Terrestrial Mammals ◽  
Technical Developments ◽  
High Resolution Imagery ◽  
Human Operators ◽  
The Impact

In the context of global biodiversity loss, wildlife population monitoring is a major challenge. Some innovative techniques such as the use of drones—also called unmanned aerial vehicle/system (UAV/UAS)—offer promising opportunities. The potential of UAS-based wildlife census using high-resolution imagery is now well established for terrestrial mammals or birds that can be seen on images. Nevertheless, the ability of UASs to detect non-conspicuous species, such as small birds below the forest canopy, remains an open question. This issue can be solved with bioacoustics for acoustically active species such as bats and birds. In this context, UASs represent an interesting solution that could be deployed on a larger scale, at lower risk for the operator, and over hard-to-reach locations, such as forest canopies or complex topographies, when compared with traditional protocols (fixed location recorders placed or handled by human operators). In this context, this study proposes a methodological framework to assess the potential of UASs in bioacoustic surveys for birds and bats, using low-cost audible and ultrasound recorders mounted on a low-cost quadcopter UAS (DJI Phantom 3 Pro). The proposed methodological workflow can be straightforwardly replicated in other contexts to test the impact of other UAS bioacoustic recording platforms in relation to the targeted species and the specific UAS design. This protocol allows one to evaluate the sensitivity of UAS approaches through the estimate of the effective detection radius for the different species investigated at several flight heights. The results of this study suggest a strong potential for the bioacoustic monitoring of birds but are more contrasted for bat recordings, mainly due to quadcopter noise (i.e., electronic speed controller (ESC) noise) but also, in a certain manner, to the experimental design (use of a directional speaker with limited call intensity). Technical developments, such as the use of a winch to safely extent the distance between the UAS and the recorder during UAS sound recordings or the development of an innovative platform, such as a plane–blimp hybrid UAS, should make it possible to solve these issues.

scholarly journals An IoT-Based Participatory Antitheft System for Public Safety Enhancement in Smart Cities

Smart Cities ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. 919-937
Author(s):  
Nikos Papadakis ◽  
Nikos Koukoulas ◽  
Ioannis Christakis ◽  
Ilias Stavrakas ◽  
Dionisis Kandris
Keyword(s):  
Smart Cities ◽  
Low Cost ◽  
Negative Influence ◽  
Asset Tracking ◽  
Tracking Tasks ◽  
Tracking Process ◽  
The Impact ◽  
Operation Center ◽  
Safety Enhancement ◽  
Selection Of

The risk of theft of goods is certainly an important source of negative influence in human psychology. This article focuses on the development of a scheme that, despite its low cost, acts as a smart antitheft system that achieves small property detection. Specifically, an Internet of Things (IoT)-based participatory platform was developed in order to allow asset-tracking tasks to be crowd-sourced to a community. Stolen objects are traced by using a prototype Bluetooth Low Energy (BLE)-based system, which sends signals, thus becoming a beacon. Once such an item (e.g., a bicycle) is stolen, the owner informs the authorities, which, in turn, broadcast an alert signal to activate the BLE sensor. To trace the asset with the antitheft tag, participants use their GPS-enabled smart phones to scan BLE tags through a specific smartphone client application and report the location of the asset to an operation center so that owners can locate their assets. A stolen item tracking simulator was created to support and optimize the aforementioned tracking process and to produce the best possible outcome, evaluating the impact of different parameters and strategies regarding the selection of how many and which users to activate when searching for a stolen item within a given area.

scholarly journals Towards Sustainable Concrete Composites through Waste Valorisation of Plastic Food Trays as Low-Cost Fibrous Materials

2021 ◽  
Vol 13 (4) ◽  
pp. 2073 ◽  
Author(s):  
Hossein Mohammadhosseini ◽  
Rayed Alyousef ◽  
Mahmood Md. Tahir
Keyword(s):  
Compressive Strength ◽  
Low Cost ◽  
Impact Resistance ◽  
Food Tray ◽  
World Population ◽  
Fibrous Materials ◽  
Palm Oil Fuel Ash ◽  
Waste Plastic ◽  
Compressive Strength Of Concrete ◽  
The Impact

Recycling of waste plastics is an essential phase towards cleaner production and circular economy. Plastics in different forms, which are non-biodegradable polymers, have become an indispensable ingredient of human life. The rapid growth of the world population has led to increased demand for commodity plastics such as food packaging. Therefore, to avert environment pollution with plastic wastes, sufficient management to recycle this waste is vital. In this study, experimental investigations and statistical analysis were conducted to assess the feasibility of polypropylene type of waste plastic food tray (WPFT) as fibrous materials on the mechanical and impact resistance of concrete composites. The WPFT fibres with a length of 20 mm were used at dosages of 0–1% in two groups of concrete with 100% ordinary Portland cement (OPC) and 30% palm oil fuel ash (POFA) as partial cement replacement. The results revealed that WPFT fibres had an adverse effect on the workability and compressive strength of concrete mixes. Despite a slight reduction in compressive strength of concrete mixtures, tensile and flexural strengths significantly enhanced up to 25% with the addition of WPFT fibres. The impact resistance and energy absorption values of concrete specimens reinforced with 1% WPFT fibres were found to be about 7.5 times higher than those of plain concrete mix. The utilisation of waste plastic food trays in the production of concrete makes it low-cost and aids in decreasing waste discarding harms. The development of new construction materials using WPFT is significant to the environment and construction industry.

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