UTERUS CANCER PROFILE IN WOMEN RESIDENTS IN MONTES CLEAR, MINAS GERAIS

Introduction: Cervical cancer is one of the most frequent in the female population, it is related to HPV infection, multiple partners, unfavorable socioeconomic conditions, among other factors. Objective: To know the profile of cervical cancer in women living in Montes Claros, Minas Gerais, Brazil. Methods: This is a descriptive study with a quantitative approach using data from patients diagnosed with cervical cancer available in hospital records of the José Alencar Gomes da Silva National Cancer Institute (INCA). Results and discussion: In the period analyzed, 555 cervical cancer diagnoses were registered in the database of the José Alencar Gomes da Silva National Cancer Institute (INCA) in the municipality investigated. Conclusion: The data available in the INCA database in relation to women residing in Montes Claros, Minas Gerais indicated adult, married, brown women, with a low level of education and occupations with low wages. Coordinated actions from all public spheres of planning and execution of women's health policy are needed to intensify early diagnosis and treatment.

Download Full-text

Rural community’s perspectives on cervical cancer screening: Report of a consensus-planning workshop

Advances in Modern Oncology Research ◽

10.18282/amor.v3.is1.199 ◽

2017 ◽

Vol 3 (s1) ◽

pp. 73

Author(s):

Smita Asthana ◽

Satyanarayana Labani

Keyword(s):

Cervical Cancer ◽

Rural Community ◽

Rural Women ◽

Elderly Women ◽

Screening Programme ◽

Cervical Screening ◽

Community Setting ◽

The Elderly ◽

Hpv Infection ◽

Using Data

The success of any screening programme depends largely on the acceptability of the community to undergo screening. This study is an attempt to explore the perspectives of rural women on screening through qualitative research, using data generated in a consensus workshop for an unscreened population prior to the start of a screening programme. The study adopted a qualitative method in the form of consensus-planning workshop prior to the start of the careHPV screening project. Knowledge about cervical cancer and human papillomavirus (HPV) infection was found to be very low. Special efforts are needed to educate the elderly women of the family and the peers of the rural community so that the project runs successfully, as their views can influence community participation. The response by rural women in undertaking selfsamplings was good. Cervical screening is acceptable and can be implemented in a rural community setting. The success of screening programme depends on health education of the rural community.

Download Full-text

Prevalence of oncogenic human papillomavirus (HPV 16/18) infection, cervical lesions and its associated factors among women aged 21–49 years in Amhara region, Northern Ethiopia

PLoS ONE ◽

10.1371/journal.pone.0248949 ◽

2021 ◽

Vol 16 (3) ◽

pp. e0248949

Author(s):

Minwuyelet Maru Temesgen ◽

Tefera Alemu ◽

Birtukan Shiferaw ◽

Seid Legesse ◽

Taye Zeru ◽

...

Keyword(s):

Cervical Cancer ◽

Logistic Regression ◽

Human Papillomavirus ◽

Associated Factors ◽

Hpv Infection ◽

Early Age ◽

Amhara Region ◽

Cervical Lesions ◽

Hpv 16 ◽

Level Of Education

Background Human papillomavirus (HPV) infection is considered as the major risk factor for the development of cervical cancer, second most frequent cancer in Ethiopia. However, the magnitude of the problem and the associated factors remain unrevealed in the Amhara region. This study aimed to determine the prevalence of HPV infection and factors contributing to the progression of HPV infection to cervical cancer. Methods Facility-based cross-sectional study design was employed among women aged 21 to 49 years of age who came for routine cervical cancer screening to 4 randomly selected hospitals (2 general and 2 referral) of Amhara region from May to October, 2019. The sample size was calculated by using the single population proportion formula, proportionated to hospitals, and women were recruited consecutively. Socio demographic and clinical data were collected using a pretested questionnaire and detection of HPV infection was done using HPV test (OncoE6TM Cervical Test) specific to HPV16/18 in cervical swabs. Visual inspection with acetic acid (VIA) was used to determine cervical lesions (precancerous and cancerous). Descriptive statistics and bivariate and multivariate logistic regression were used to describe HR-HPV and cervical lesions burden and association between HR-HPV, and cervical lesions and potential risk factors. Results Among 337 women 21 to 49 years (median age of 35 years ±SD = 7.1 years) of age enrolled in the study, The overall prevalence of oncogenic HPVs (HPV16/18) and the VIA-positivity rate, possible an indicative of cervical lesions, were 7.1% and 13.1%, respectively. Logistic regression analysis showed a significant association between early age of first sexual intercourse (COR = 2.26; 95% CI: 1.0–5.05) and level of education (COR = 0.31; 95% CI: 0.12–0.78) with cervical lesions. Higher odds of HPV positivity (COR = 1.56; 95% CI: 0.59–4.11, p = 0.36) and VIA positivity (COR = 1.39; 95% CI: 0.64–3.00, p = 0.39) were observed among participants who had a history of sexually transmitted illnesses (STIs). Conclusions There was a relatively low prevalence of oncogenic HPV 16/18 and VIA-positivity in women attending four hospitals in the Amhara Region. Early age sexual contact, high parity, and being uneducated/low level of education were independently associated factors with HR-HPV infection and development of cervical lesions, highlighting the importance of prioritizing the limited HPV testing to those risk groups.

Download Full-text

Methods for screening and prevention of HPV infection – a retrospective study

Romanian Journal of Infectious Diseases ◽

10.37897/rjid.2021.1.7 ◽

2021 ◽

Vol 24 (1) ◽

pp. 51-57

Author(s):

Catalina Diana Stanica ◽

◽

Romina Marina Sima ◽

Raluca Gabriela Ioan ◽

Constantin Dimitrie Nanu ◽

...

Keyword(s):

Cervical Cancer ◽

Retrospective Study ◽

Screening Program ◽

Cervical Screening ◽

Hpv Vaccination ◽

Hpv Infection ◽

Female Population ◽

Vaccination Programs ◽

Screening Programs ◽

Incidence And Mortality

Worldwide, cervical cancer ranks 4th in frequency in the female population, with about half of the cases being fatal. In Romania, it is the second type of cancer found in women, after breast cancer and the main cause of cancer mortality in patients aged between 15 and 44 years. The main cause of this type of cancer is human papilloma virus (HPV) infection. Although HPV is very widespread (> 85%), progression to cervical cancer is relatively rare. In countries that have implemented cervical screening programs, the incidence and mortality caused by this pathology have decreased by 50-75%. Also, the emergence of vaccines against the most common strains of oncogenic HPV and the implementation of vaccination programs will bring additional benefits in preventing cervical cancer. This paper presents the results of a retrospective study, performed on a number of 92 patients, which aimed to know the distribution of different HPV genotypes, their impact on the cervical epithelium, the degree of access to the national screening program, and openness to anti HPV vaccination.

Download Full-text

Epidemiology and costs of HPV infection: review of the evidence

Farmeconomia Health economics and therapeutic pathways ◽

10.7175/fe.v9i4.236 ◽

2008 ◽

Vol 9 (4) ◽

pp. 183-189 ◽

Cited By ~ 1

Author(s):

Francesco Bamfi ◽

Alessia Marocco ◽

Stefano Capri ◽

Mario Giovanni Sideri

Keyword(s):

Cervical Cancer ◽

Epidemiological Data ◽

Genital Warts ◽

Hpv Infection ◽

Cervix Cancer ◽

Hpv 16 ◽

Female Population ◽

Italian National Health Service ◽

Italian National Health ◽

The Impact

HPV infection is a well-established cause of both benign and malign diseases. The HPV 16 and 18 genotypes are most commonly associated with cervical cancer whereas the HPV 6 and 11 genotypes are most commonly associated with anogenital warts. In Italy are currently approved two types of vaccine: Gardasil® is a tetravalent HPV 6, 11, 16 and 18 vaccine that prevents cervix cancer and genital warts, Cervarix® is a bivalent HPV 16 and 18 genotype vaccine that protects against cervical cancer and pre cancer forms. Aim of present study was to collect the available epidemiological data and the impact on the Italian National Health Service (NHS) budget of genital warts pathology. In Italy 40,000 genital warts cases per year could be estimated in the female population. The management cost in charge of Italian NHS for the female pathology is evaluated around 7 millions €. Comparing the available evidence NHS costs for genital wart pathology represent 3-4% of the total amount for prevention and treatment of cervix cancer.

Download Full-text

Complementary and Innovative Method in Genital HPV Testing for Cervical Cancer Prevention

Acta Medica Transilvanica ◽

10.2478/amtsb-2020-0073 ◽

2020 ◽

Vol 25 (4) ◽

pp. 54-56

Author(s):

Georgeta Gînfălean

Keyword(s):

Cervical Cancer ◽

Precancerous Lesions ◽

Screening Method ◽

Transmitted Disease ◽

Hpv Infection ◽

Cervical Cancer Prevention ◽

Hpv Testing ◽

Female Population ◽

Innovative Method ◽

Prevention Programmes

Abstract Considering actual SARS-COV 2 pandemic, the comfort and time of the female patient’ trend is to minimize the time spent in the doctor’s office, so that auto-testing is a solving problem in this context. This paper aims at the importance of self-collected urine and vaginal samples, since actual studies are showing that is a complementary method in HPV-testing and a screening method for prevention of cervical cancer. Genital HPV infection is responsible for approximately 99% of cervical cancers, and is considered a sexually transmitted disease. Given that eight out of ten patients have at least one episode of HPV infection in their lifetime, there is a need for a method of early detection of genital HPV infection. Cervical cancer is the second type of diagnosed cancer in the rank of genital cancers and the third leading cause of cancer death among the female population. In Romania, the frequency of cervical cancer and mortality caused by this type of cancer remains high. In 2018 Globocan, it was mentioned that the occurrence of cervical cancer in Romania was 8.6%, and the mortality was 19.5/10,000 women. Worldwide, the following have been implemented: primary prevention programmes (via immunization) and secondary prevention programmes – traditional cytological testing, to which co-tests have been added. In the co-testing sector, there has been found with an updated visa – the self-harvesting test, being considered a complementary and innovative method in genital HPV testing, which aims to: identify the presence of highly oncogenic HPV strains with a marked sensitivity. Self-harvesting testing aims to: signal the presence of highly oncogenic strains, extrapolation can lead to early identification of the number of cases of precancerous lesions of the cervix and implicitly of cervical cancer.

Download Full-text

PENIS CANCER PROFILE IN PATIENTS RESIDENT IN MINAS GERAIS

Health and Society ◽

10.51249/hs.v1i06.579 ◽

2021 ◽

Vol 1 (06) ◽

Author(s):

Kemberly Norrany Alves Ferreira da Silva ◽

Cinara Ferreira Coutinho ◽

Larissa Cristiny Mendes Viana ◽

Nadine Antunes Teixeira ◽

Leidaiane Pego Batista ◽

...

Keyword(s):

Risk Factors ◽

High School ◽

Health Services ◽

National Cancer Institute ◽

Penile Cancer ◽

Descriptive Study ◽

Minas Gerais ◽

Socioeconomic Conditions ◽

Hospital Records ◽

Agricultural Worker

Introduction: Penile cancer are rare neoplasms, being more frequent in men aged 50 years or older, although it may affect men of any age. Unfavorable socioeconomic conditions, poor intimate hygiene, HPV infections, among others, are risk factors for this type of cancer. Objective: To know the profile of penile cancer in patients living in the state of Minas Gerais, Brazil. Methods: A descriptive study of quantitative approach was conducted through data from patients diagnosed with penile cancer in hospital records of the José Alencar Gomes da Silva National Cancer Institute (INCA). Results and discussion: In the period from 2015 to 2019, 573 diagnoses of penile cancer were recorded in the database of the José Alencar Gomes da Silva National Cancer Institute (INCA). Conclusion: Men aged between 50 and 74 years, married, brown and with incomplete high school were identified, the main occupation was agricultural worker. It is essential that in order to face this problem, men's health is considered routinely and systematically in the routine health services.

Download Full-text

A combined ultrastructural and gene molecular research for the relationship between human uterine cervical carcinoma and human papillomavirus

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010015856x ◽

1990 ◽

Vol 48 (3) ◽

pp. 204-205

Author(s):

Kun Lee ◽

Jingyi Si ◽

Ricai Han ◽

Wei Zhang ◽

Bingbing Tan ◽

...

Keyword(s):

Cervical Cancer ◽

Human Papillomavirus ◽

Intraepithelial Neoplasia ◽

Hpv Infection ◽

Dot Blot ◽

Homologous Sequences ◽

Normal Cervical Epithelium ◽

The Relationship ◽

Chronic Cervicitis

There are more supports for the view that human papillomavirus (HPV) infection might be an etiological factor in the development of cervical cancer when the association of persistent condylomata is considered. Biopsies from 318 cases with squamous cell carcinoma of uterine cervix, 48 with cervical and vulvar condylomata, 14 with cervical intraepithelial neoplasia (CIN), 34 with chronic cervicitis and 24 normal cervical epithelium were collected from 5 geographic regions of China with different cervical cancer mortalities. All specimens were prepared for Dot blot, Southern blot and in situ DNA-DNA hybridizations by using HPV-11, 16, 18 DNA labelled with 32P and 3H as probes to detect viral homologous sequences in samples. Among them, 32 cases with cervical cancer, 27 with condyloma and 10 normal cervical epitheliums were randomly chosen for comparative EM observation. The results showed that: 1), 192 out of 318 (60.4%) cases of cervical cancer were positive for HPV-16 DNA probe (Table I)

Download Full-text

Efficiency of diagnosis and treatment non-invasive and microinvasive sgamous cell cervical cancer

HEALTH OF WOMAN ◽

10.15574/hw.2020.149.71 ◽

2020 ◽

pp. 71-74

Author(s):

M.M. Melnyk ◽

◽

S.V. Nespradko ◽

I.V. Goncharuk ◽

M.V. Marchenko ◽

...

Keyword(s):

Cervical Cancer ◽

Key Words ◽

National Cancer Institute ◽

Reproductive Function ◽

Diagnosis And Treatment ◽

Non Invasive ◽

Corpus Uteri ◽

Complex Program ◽

Early Cervical Cancer

The objective: analyse the effectiveness of diagnosis and treatment for early cervical cancer. Materials and methods. Analysed 107 cases of women’s disease on CIN ІІІ, cancer in situ, they were on treatment in National cancer institute and Kyiv dictrict cancer dispensary from 2010 till 2015 years. Results. Diagnosed percent relapse CIN ІІІ, cancer in situ contain 4.57% uninvasive and invasive form – 0.94%. Conclusion. According diagnostic CIN ІІ and CIN ІІІ is recommended to do treatment conization and dynamic dispensary observation. Are making complex program of infection HPV16, 18. In appering of margins resection some elements of tumor after wider conization by forms of cancer in situ. Many of expansive burns in cervical glands, in making of reproductive function, going disease (nodel leiomyoma of corpus uteri etc). In perspective is accept the notion of looking after and screening research of considering infection HPV16, 18 on CIN І, CIN ІІ. Key words: cervical cancer, сancer in situ, CIN І–ІІІ, diagnostic, treatment, conization.

Download Full-text