Chromium, Nickel and Iron as clues to the formation histories of exoplanetary bodies

Author(s):  
Andrew Buchan ◽  
Amy Bonsor ◽  
Oliver Shorttle ◽  
Jon Wade ◽  
John Harrison

<p>We are now entering an era of rocky exoplanet detection. To determine whether an exoplanet is ‘Earth-like’, we must estimate not only its mass, radius and insolation, but also its geological composition. These geological constraints have wide ranging implications, not least for a planet’s subsequent evolution and habitability.</p><p>Polluted white dwarfs which have accreted fragments of planetary material provide a unique opportunity to probe exoplanetary interiors. We can also learn about their formation histories, including the geological process of core-mantle differentiation.</p><p>Cr, Ni and Fe behave differently during differentiation, depending on the conditions under which it occurs. This alters the Cr/Fe and Ni/Fe ratios in the core and mantle of differentiated bodies. The pressure inside the body is a key parameter, and depends on the body’s size.</p><p>In our work, we present a novel approach for modelling this behaviour and use it to gain crucial insight into the sizes of exoplanetary bodies which pollute white dwarfs.</p>

Author(s):  
David Carus

This chapter explores Schopenhauer’s concept of force, which lies at the root of his philosophy. It is force in nature and thus in natural science that is inexplicable and grabs Schopenhauer’s attention. To answer the question of what this inexplicable term is at the root of all causation, Schopenhauer looks to the will within us. Through will, he maintains that we gain immediate insight into forces in nature and hence into the thing in itself at the core of everything and all things. Will is thus Schopenhauer’s attempt to answer the question of the essence of appearance. Yet will, as it turns out, cannot be known immediately as it is subject to time, and the acts of will, which we experience within us, do not correlate immediately with the actions of the body (as Schopenhauer had originally postulated). Hence, the acts of will do not lead to an explanation of force, which is at the root of causation in nature. Schopenhauer sets out to explain what is at the root of all appearances, derived from the question of an original cause, or as Schopenhauer states “the cause of causation,” but cannot determine this essence other than by stating that it is will; a will, however, that cannot be immediately known.


2018 ◽  
Vol 26 (6) ◽  
pp. 1611-1622 ◽  
Author(s):  
Vibeke Bruun Lorentsen ◽  
Dagfinn Nåden ◽  
Berit Sæteren

Background: People with progressive cancer experience that their bodies change due to disease and/or treatment. The body is integral to the unity of the human being, a unity that must be perceived as whole if dignity shall be experienced. Relatives are in touch with the suffering bodies of their dear ones, physically, socially, mentally, and existentially, and thus the relatives’ experiences of the bodies of their dear ones might yield insight into the concept of dignity. Aim: The aim of this study is to explore relatives’ experiences of the patients’ bodily changes from a perspective of dignity. Research design and method: A total of 12 relatives from a hospice in Norway were interviewed. Gadamer’s ontological hermeneutics inspired the interpretation. Ethical considerations: The principles of voluntariness, confidentiality, withdrawal, and anonymity were respected during the whole research process. The Norwegian Social Science Data Services approved the study. Results and conclusion: The conversations about the body were conversations about ambivalent or paradoxical matters that shed light on the concept of dignity. The results show that the relatives got in touch with elements that otherwise would have remained tacit and unspoken, and which gave glimpses of a deeper truth, which might reveal the core of dignity. Furthermore, the relatives’ confirmation of the ambivalence might be understood as a strong ethical obligation to treat the other with dignity. The confirmation may also reveal the relatives’ unselfish love of the other, which can be understood as the core of ethics and ethos. Finally, the results reveal the relatives’ limited insight into their dear ones’ bodily changes, and we discuss the challenges of truly seeing the other. Body knowledge and the relationship between body and dignity as phenomena cannot be ignored and needs more attention and articulation in clinical nursing practice and in nursing research.


Author(s):  
Umesh B. Wahul ◽  
Ambadas S. Kadam ◽  
Laxmikant H. Kamble ◽  
Ayaz S. Ali

The screening of perfect diuretics for non –clinical utility in Diabetes mellitus is a relatively novel approach which gain insight into underlying the pathophysiological processes. This study aim to evaluate the diuretic effect of crude aqueous & alcoholic extract of M. charantia Linn. using Albino Wistar Rat model. The methodology of animal study includes the spectral analysis of Na+, K+, Cl-concentration against the body weight, this was done by spectrophotometry. In this study, the comparative observation of Diuretic activity with standard and extracted compound has shown that the estimated 24‐hour urine contains the Na+-3.82 g, 3.82 g, 3.92 g  and K+-1.35 g, 1.39 g, 1.48 gwt. For Vehicle control, Standard drug, and Extracted compound respectively. Which possess the favouring result means from the spot urine were 10.7±7.0 g/24 hand 3.9±2.1 g/24 h, respectively. Coefficients were 0.035, 0.022, 0.046 at (d±2SD=7.07 g, 4.42 gand 8.92 g) for sodium chloride and 0.068, 0.031, 0.046 at (d ± 2SD = 4.92 g, 2.31 g and 3.34 g) for potassium chloride. The present study guide formulation of non-clinical trials with statistical study to further measuring the claimed efficacy of M. charantia as a natural remedy for diabetes mellitus.


CounterText ◽  
2016 ◽  
Vol 2 (2) ◽  
pp. 217-235
Author(s):  
Gordon Calleja

This paper gives an insight into the design process of a game adaptation of Joy Division's Love Will Tear Us Apart (1980). It outlines the challenges faced in attempting to reconcile the diverging qualities of lyrical poetry and digital games. In so doing, the paper examines the design decisions made in every segment of the game with a particular focus on the tension between the core concerns of the lyrical work being adapted and established tenets of game design.


Author(s):  
Zoran Vrucinic

The future of medicine belongs to immunology and alergology. I tried to not be too wide in description, but on the other hand to mention the most important concepts of alergology to make access to these diseases more understandable, logical and more useful for our patients, that without complex pathophysiology and mechanism of immune reaction,we gain some basic insight into immunological principles. The name allergy to medicine was introduced by Pirquet in 1906, and is of Greek origin (allos-other + ergon-act; different reaction), essentially representing the reaction of an organism to a substance that has already been in contact with it, and manifested as a specific response thatmanifests as either a heightened reaction, a hypersensitivity, or as a reduced reaction immunity. Synonyms for hypersensitivity are: altered reactivity, reaction, hypersensitivity. The word sensitization comes from the Latin (sensibilitas, atis, f.), which means sensibility,sensitivity, and has retained that meaning in medical vocabulary, while in immunology and allergology this term implies the creation of hypersensitivity to an antigen. Antigen comes from the Greek words, anti-anti + genos-genus, the opposite, anti-substance substance that causes the body to produce antibodies.


2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Simon Elias Bibri

AbstractA new era is presently unfolding wherein both smart urbanism and sustainable urbanism processes and practices are becoming highly responsive to a form of data-driven urbanism under what has to be identified as data-driven smart sustainable urbanism. This flourishing field of research is profoundly interdisciplinary and transdisciplinary in nature. It operates out of the understanding that advances in knowledge necessitate pursuing multifaceted questions that can only be resolved from the vantage point of interdisciplinarity and transdisciplinarity. This implies that the research problems within the field of data-driven smart sustainable urbanism are inherently too complex and dynamic to be addressed by single disciplines. As this field is not a specific direction of research, it does not have a unitary disciplinary framework in terms of a uniform set of the academic and scientific disciplines from which the underlying theories can be drawn. These theories constitute a unified foundation for the practice of data-driven smart sustainable urbanism. Therefore, it is of significant importance to develop an interdisciplinary and transdisciplinary framework. With that in regard, this paper identifies, describes, discusses, evaluates, and thematically organizes the core academic and scientific disciplines underlying the field of data-driven smart sustainable urbanism. This work provides an important lens through which to understand the set of established and emerging disciplines that have high integration, fusion, and application potential for informing the processes and practices of data-driven smart sustainable urbanism. As such, it provides fertile insights into the core foundational principles of data-driven smart sustainable urbanism as an applied domain in terms of its scientific, technological, and computational strands. The novelty of the proposed framework lies in its original contribution to the body of foundational knowledge of an emerging field of urban planning and development.


Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 412
Author(s):  
Natalia Rakislova ◽  
Lorena Marimon ◽  
Mamudo R. Ismail ◽  
Carla Carrilho ◽  
Fabiola Fernandes ◽  
...  

Postmortem studies are crucial for providing insight into emergent diseases. However, a complete autopsy is frequently not feasible in highly transmissible diseases due to biohazard challenges. Minimally invasive autopsy (MIA) is a needle-based approach aimed at collecting samples of key organs without opening the body, which may be a valid alternative in these cases. We aimed to: a) provide biosafety guidelines for conducting MIAs in COVID-19 cases, b) compare the performance of MIA versus complete autopsy, and c) evaluate the safety of the procedure. Between October and December 2020, MIAs were conducted in six deceased patients with PCR-confirmed COVID-19, in a basic autopsy room, with reinforced personal protective equipment. Samples from the lungs and key organs were successfully obtained in all cases. A complete autopsy was performed on the same body immediately after the MIA. The diagnoses of the MIA matched those of the complete autopsy. In four patients, COVID-19 was the main cause of death, being responsible for the different stages of diffuse alveolar damage. No COVID-19 infection was detected in the personnel performing the MIAs or complete autopsies. In conclusion, MIA might be a feasible, adequate and safe alternative for cause of death investigation in COVID-19 cases.


2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Mehrshad Golesorkhi ◽  
Javier Gomez-Pilar ◽  
Shankar Tumati ◽  
Maia Fraser ◽  
Georg Northoff

AbstractThe human cortex exhibits intrinsic neural timescales that shape a temporal hierarchy. Whether this temporal hierarchy follows the spatial hierarchy of its topography, namely the core-periphery organization, remains an open issue. Using magnetoencephalography data, we investigate intrinsic neural timescales during rest and task states; we measure the autocorrelation window in short (ACW-50) and, introducing a novel variant, long (ACW-0) windows. We demonstrate longer ACW-50 and ACW-0 in networks located at the core compared to those at the periphery with rest and task states showing a high ACW correlation. Calculating rest-task differences, i.e., subtracting the shared core-periphery organization, reveals task-specific ACW changes in distinct networks. Finally, employing kernel density estimation, machine learning, and simulation, we demonstrate that ACW-0 exhibits better prediction in classifying a region’s time window as core or periphery. Overall, our findings provide fundamental insight into how the human cortex’s temporal hierarchy converges with its spatial core-periphery hierarchy.


RSC Advances ◽  
2015 ◽  
Vol 5 (107) ◽  
pp. 88234-88240 ◽  
Author(s):  
Satish K. Pandey ◽  
Praveen Rishi ◽  
C. Raman Suri ◽  
Aaydha C. Vinayaka

CdTe QD based stripping voltammetry for Vi capsular polysaccharide detection. The technique has provided an insight into the competence of CdTe QD and GNP immuno-conjugates. This is a novel approach to characterize the efficiency of immuno-conjugates of QDs and GNPs.


Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2780
Author(s):  
Zahra Rahemtulla ◽  
Theodore Hughes-Riley ◽  
Tilak Dias

Overexposure to hand transmitted vibrations (HTVs) from prolonged use of vibrating power tools can result in severe injuries. By monitoring the exposure of a worker to HTVs, overexposure, and injury, can be mitigated. An ideal HTV-monitoring system would measure vibration were it enters the body, which for many power tools will be the palm and fingers, however this is difficult to achieve using conventional transducers as they will affect the comfort of the user and subsequently alter the way that the tool is held. By embedding a transducer within the core of a textile yarn, that can be used to produce a glove, vibration can be monitored close to where it enters the body without compromising the comfort of the user. This work presents a vibration-sensing electronic yarn that was created by embedding a commercially available accelerometer within the structure of a yarn. These yarns were subsequently used to produce a vibration-sensing glove. The purpose of this study is to characterize the response of the embedded accelerometer over a range of relevant frequencies and vibration amplitudes at each stage of the electronic yarn’s manufacture to understand how the yarn structure influences the sensors response. The vibration-sensing electronic yarn was subsequently incorporated into a fabric sample and characterized. Finally, four vibration-sensing electronic yarns were used to produce a vibration-sensing glove that is capable of monitoring vibration at the palm and index finger.


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