scholarly journals Diabetes Mellitus among Newly Diagnosed Tuberculosis Patients during COVID-19 Pandemic Period in a Secondary Health Institution

2021 ◽  
Vol 6 (2) ◽  
pp. 88-91
Author(s):  
Parul Bhardwaj ◽  
Shivbrat Sharma
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Pulmonary Tuberculosis ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Newly Diagnosed ◽  
Tuberculosis Patients ◽  
Civil Hospital ◽  
Keywords Tuberculosis

Introduction: Tuberculosis is one of the major public health problems worldwide and it is a major cause of morbidity and mortality. The risk of TB infection not only rises in diabetes patients, but is also associated with a higher risk of an increased number of diabetes complications. This study was conducted to determine the prevalence of Diabetes Mellitus (DM) among patients with newly diagnosed TB in Civil hospital Dehra, district Kangra (HP) a secondary health institute. AIM: To study the prevalence of DM in newly diagnosed pulmonary tuberculosis patients. Materials and Methods: Total 40 newly diagnosed patients with pulmonary tuberculosis (TB) who came in medicine OPD, Civil hospital Dehra from August 2020 to April 2021 during COVID -19 pandemic period were enrolled in the study. Their fasting blood glucose (FBG) was done. Screening and diagnosis of DM was done according to American diabetes association (ADA) guidelines. Results: The prevalence of DM and impaired fasting glucose (IFG) in newly diagnosed tubercular patients was 10% and 12.5% respectively in our study. Conclusion: The prevalence of FBS was found to be higher in patients with TB than the general population. Hence it is very important to screen these patients timely to prevent further complications. Keywords: Tuberculosis (TB), diabetes mellitus (DM), impaired fasting glucose (IFG), fasting blood glucose (FBG).

DIABETES MELLITUS PREDICTION;

2012 ◽  
Vol 20 (01) ◽  
pp. 060-067
Author(s):  
SIKANDAR HAYAT KHAN ◽  
SYED AOWN RAZA BOKHARI ◽  
AAMIR IJAZ ◽  
Mohammad Zafar Ali ◽  
Umair Masood ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Total Cholesterol ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Rapid Change ◽  
Serum Total Cholesterol ◽  
Newly Diagnosed ◽  
Diagnosis Of Diabetes Mellitus

ABSTRACT… Background: The rapid change in lifestyles and dietary has led to a pandemic of diabetes mellitus. The diagnosis ofdiabetes mellitus sometimes requires 2 hr OGTT sampling. Recent evidence has shown that there are lipid related abnormalitiesassociated with diabetes mellitus, so a consideration comes in for their utilization as a marker to support diabetes mellitus. Objective: (1)To correlate serum total cholesterol, triglycerides and ALT with fasting blood glucose (2). To predict diagnosis of diabetes mellitus usingabove serum markers. Design: Cross-sectional analysis, descriptive study. Place and duration of study: This study was carried outbetween Mar-2010 to Jan-2011 at the department of pathology, PNS RAHAT in collaboration with PNS SHIFA. Subjects and methods: Atotal of 251 subjects were screened for presence of glucose dysregulation. Based upon the results of fasting blood glucose, subjectswere grouped as having normal glucose tolerance (NGT), impaired fasting glucose (IFG), and newly diagnosed diabetes mellitus (NDDM).A comparison of lipids including triglycerides, total cholesterol and alanine aminotransferase (ALT) were made in the above groups tomeasure the differences between the above mentioned three groups. ALT, triglyceride and total cholesterol were correlated with results offasting blood glucose through pearson’s correlation. Later the performance of different cut-offs of triglycerides, total cholesterol and twomathematical models [{Factor-I=FBG (mmol/L) + triglycerides (mmol/L)} and {Factor-II=FBG (mmol/L) + triglycerides (mmol/L) +total cholesterol (mmol/L)}] were evaluated for detecting diabetes mellitus against the gold standard 2 hr OGTT in 71 subjects. Results:The results of triglycerides, total cholesterol and serum ALT between the three groups were as: [{Triglycerides: NGT =1.91, IFG=2.10,NDDM= 2.75, p=0.003} {total cholesterol: NGT=5.03, IFG=5.19, NDDM=5.74, p=0.056} {ALT:NGT=28.47, IFG=27.95,NDDM=25.78, p=0.846}]. Most correlation was found between serum triglycerides and fasting blood glucose (r2=0.235, p<0.001);while serum total cholesterol and ALT showed lesser correlations {(total cholesterol:r2= 0.172, P=0.007), (ALT:r2= 0.010,p=0.877)}. While triglycerides demonstrated superiority in terms of sensitivity to total cholesterol for detection of diabetes mellitus, thefactors incorporating lipids and glucose had the highest overall diagnostic efficiency. Conclusions: Triglycerides and total cholesterollevels rise from normoglycemic individuals to subjects having impaired fasting glucose and newly diagnosed diabetics. The inclusion oftriglycerides and total cholesterol for diagnosis of diabetes mellitus improves the chances of for detection of diabetes mellitus.

Circulating Netrin-1 as a Novel Biomarker for Impaired Fasting Glucose and Newly Diagnosed Type 2 Diabetes Mellitus

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1535-P ◽  
Author(s):  
HYE-IN JUNG ◽  
JAEHYUN BAE ◽  
EUGENE HAN ◽  
GYURI KIM ◽  
JI-YEON LEE ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Newly Diagnosed

scholarly journals Association of a Self-Paid Medically Supervised Weight Management Program with Reversal of Obesity-Associated Impaired Fasting Glucose

2021 ◽  
Vol 11 (2) ◽  
pp. 386-394
Author(s):  
Vijaya Surampudi ◽  
Xinkai Zhou ◽  
Chi-Hong Tseng ◽  
David Heber ◽  
Zhaoping Li
Keyword(s):  
Weight Loss ◽  
Blood Glucose ◽  
Retrospective Analysis ◽  
Weight Management ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Management Program ◽  
Weight Management Program ◽  
Glucose Levels

Aims: The progression of prediabetes to T2DM can be delayed through diet modification and weight management. However, the intensive lifestyle program is often not covered by medical insurance. This retrospective analysis evaluates the association of a patient self-paid weight management program on an improvement of blood sugar in overweight and obese patients with impaired fasting glucose (IFG). Methods: The medical records of 4634 patients who participated in the self-pay UCLA Weight Management Program were reviewed and 2572 patients met the criteria for this retrospective analysis to examine whether this program was associated with the reversal of IFG over 3 months among 1396 patients with normal fasting glucose (NFG) and 1176 with IFG. Results: The patients with IFG lost comparable amounts of weight (10.5 ± 1.3 kg) at three months, as did the subjects with NFG (10.1 ± 1.3 kg). Fasting blood glucose in the IFG group decreased from 108.49 ± 6.4 to 101.8 ± 9.41 mg/dL (p < 0.0001) after three months. There were also significant reductions in triglycerides, and both systolic and diastolic blood pressure in both groups in association with weight loss. Conclusion: Our medically supervised self-pay multidisciplinary weight management program was associated with reduced fasting blood glucose levels in patients with IFG over three months with comparable weight loss to patients with NFG.

scholarly journals Prevalence of newly diagnosed prediabetes, diabetes mellitus among the officers from Phuoc Long district of Binh Phuoc province

2021 ◽  
pp. 24-28
Author(s):  
Thanh Long Le ◽  
Trung Vinh Hoang
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Newly Diagnosed ◽  
Personal Communications

Objective: To evaluate the prevalence of newly diagnosed prediabetes, diabetes mellitus among the officers from Phuoc Long district of Binh Phuoc province. Subjects and methods: 268 personals communications service was examined the impaired fasting glucose (G0); impaired glucose tolerance (G2) anh HbA1c. Results: Prevalence of prediabetes, type 2 diabetes mellitus by G0, G2, HbA1c as follows 16,0%; 13,1%; 17,9% and 3,8%; 6,7%; 2,2%. Common prevalence of prediabetes in 26,9%; type 2 diabetes mellitus in 7,1%. Conclusion: Personal communications service from Phuoc Long district have percentage of prediabetes higher compared to type 2 diabetes mellitus which of prediabetes was diagnosed by HbA1c which takes up the highest percentage; diabetes mellitus was diagnosed by G2which takes up the highest percentage.

Triglyceride levels and risk of type 2 diabetes mellitus: a longitudinal large study

2016 ◽  
Vol 64 (2) ◽  
pp. 383-387 ◽  
Author(s):  
Amani Beshara ◽  
Eytan Cohen ◽  
Elad Goldberg ◽  
Pearl Lilos ◽  
Moshe Garty ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Impaired Fasting Glucose ◽  
Triglyceride Level ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Serum Triglyceride ◽  
Stepwise Logistic Regression ◽  
Serum Triglyceride Level ◽  
Normal Range ◽  
Wide Range

The relationship between triglyceridemia and diabetes mellitus remains unclear. This study evaluated the risk of diabetes and impaired fasting glucose associated with a wide range of triglyceride levels. A longitudinal retrospective study was carried out employing data from a screening center between the years 2000 and 2012. Inclusion criteria were absence of diabetes at baseline and attendance at the center at least twice over a 5-year period. Participants were divided by fasting blood glucose level (normal/impaired) at the first visit. A total of 5085 participants were eligible for the study. Of the 4164 normoglycemic participants at baseline, 40 (0.96%) had diabetes and 998 (24%) had impaired fasting glucose by the end of the study. On stepwise logistic regression analysis, every 10 mg/dL increase in triglyceride level significantly increased the risk of diabetes by 4% and of impaired fasting glucose by 2% (p<0.001). This association held true even when rising triglyceride levels remained within the accepted normal range (<150 mg/dL, p<0.001). Sustained increments in serum triglyceride level, even within the accepted normal range, are an independent risk factor for diabetes mellitus and impaired fasting glucose in normoglycemic participants.

scholarly journals Screening of newly-diagnosed adults with Tuberculosis for Diabetes mellitus and Impaired Glucose Tolerance in a Local Government Area in Ogun State, Nigeria

2019 ◽  
pp. 146-155
Author(s):  
AA Salako ◽  
OA Adenowo ◽  
OE Amoran ◽  
O Odusan ◽  
GJ Mautin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Treatment Outcomes ◽  
Fasting Blood Glucose ◽  
Newly Diagnosed ◽  
Glucose Levels ◽  
Ogun State ◽  
Blood Glucose Levels

Background: Emerging patterns in epidemiological transitions have led to increased risk for Non-Communicable Diseases and infectious conditions globally. Diabetes mellitus (DM) in a population is one such risk factor that could lead to the development of Tuberculosis (TB) due to weakened immune functions in affected persons, with implications for mortality. If not diagnosed early, DM also leads to poor treatment outcomes in TB. Objective: To assess the prevalence of DM and impaired glucose tolerance (pre-diabetes) among newly diagnosed tuberculosis cases in Ijebu-Ode Local Government Area of Ogun State, Nigeria. Methods: This cross-sectional study was conducted among 100 newly diagnosed Pulmonary TB patients in ljebu-Ode LGA. The patients were selected from four health facilities and were screened for elevated Fasting Blood Glucose levels using a laboratory spectrophotometer (glucose oxidase method). Results: The mean age of the 100 study participants was 33 years (± 9.82), with ages within 19 -62 years. Eleven (11.0%) had elevated blood glucose levels suggestive of DM, while 20 (20.0%) had impaired fasting blood glucose levels. Among these 31 patients, 18 (58.0%) were males while 13 (42.0%) were females. The modal ages were within 20-39 years. Conclusion: Screening for DM by healthcare providers should be routinely conducted before commencing TB patients on treatment. This will aid early detection, improve treatment outcomes of TB and prevent mortality among patients with these co-morbidities.

scholarly journals Frequency of impaired fasting glucose in first degree relatives of Type-II diabetic patients and its association with Body Mass Index

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Alia Ali Muhammed ◽  
Azeem Taj ◽  
Muhammed Uthman Ahmed ◽  
Elsa Tabrez
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Impaired Fasting Glucose ◽  
Type Ii Diabetes ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Type Ii ◽  
Glucose Levels ◽  
First Degree Relatives

Objectives: To determine the frequency of impaired fasting glucose in first degree relatives of people with Type-II diabetes and its association with BMI. Methods: This cross-sectional study was conducted in Diabetic clinic of Shaikh Zayed Hospital, Lahore from July to December 2017. Individuals aged ≥35 years, first degree relatives of people with Type-II diabetes, were selected and their fasting blood glucose levels were checked twice a week apart. Study participants were divided into 3 groups. Group-I were those with normal fasting blood glucose (FBS: <100mg/dl), Group-II were those with impaired fasting glucose (100-125mg/dl), considered as high risk and Group-III included those who turned out to be having frank diabetes (FBS: ≥126mg/dl). Exclusion criteria were known diabetes and pregnancy. Proportions of impaired fasting glucose levels versus BMI were compared using Chi-square test. Significance was considered at P <0.001. Results: A total of hundred subjects were included in the study with the mean age of 44.27 years. Sixty percent participants had normal FBS, 31% showed impaired FBS and 09% had frank diabetes (P <0.001). Significant association was found between impaired fasting glucose and BMI, as with increasing BMI the frequency of impaired fasting glucose increases. Conclusion: First-degree relatives of people with Type-II diabetes showed higher frequency of impaired fasting glucose and obesity was an important risk factor. doi: https://doi.org/10.12669/pjms.36.3.57 How to cite this:Ali A, Taj A, Ahmed MU, Tabrez E. Frequency of impaired fasting glucose in first degree relatives of Type-II diabetic patients and its association with Body Mass Index. Pak J Med Sci. 2020;36(3):407-411. doi: https://doi.org/10.12669/pjms.36.3.57 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Pre-impaired Fasting Glucose State Is A Risk Factr for Endothelial Dysfunction Flow-mediated Dilation Japan (FMD-J) Study

2020 ◽  
Author(s):  
Takayuki Yamaji ◽  
Takahiro Harada ◽  
Yu Hashimoto ◽  
Yuji Takaeko ◽  
Masato Kajikawa ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Endothelial Dysfunction ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Large Sample Size ◽  
Clinical Trial Registry ◽  
Significant Difference

Abstract Background There is little information on the relationships of fasting blood glucose (FBG) including high normal blood glucose and impaired fasting glucose (IFG) with endothelial function. The purpose of this study was to evaluate the relationship between FBG level and flow-mediated vasodilation (FMD) in detail using a large sample size. Methods This study was a cross-sectional study. We measured FMD in 7265 subjects at 31 general hospitals. The subjects were divided into four groups based on FBG levels: <5.55 mmol/L, 5.55–6.05 mmol/L, 6.11–6.94 mmol/L, and ≥ 6.99 mmol/L or known type 2 diabetes. The subjects were also divided into six groups based on FBG levels: <5.00 mmol/L, 5.00-5.22 mmol/L, 5.27–5.50 mmol/L, 5.55–6.05 mmol/L, 6.11–6.94 mmol/L, and ≥ 6.99 mmol/L or known type 2 diabetes. Results FMD decreased in relation to increase in FBG level. There was a significant difference in FMD between the FBG of < 5.55 mmol/L group and the other three groups (6.7 ± 3.1% vs. 5.9 ± 2.8%, 5.7 ± 3.1%, and 5.1 ± 2.6%; p < 0.001, respectively). After adjustment for confounding factors, the odds of having the lowest quartile of FMD was significantly higher in the FBG of 5.27–5.50 mmol/L, 5.55–6.05 mmol/L, 6.11–6.94 mmol/L, and ≥ 6.99 mmol/L or known type 2 diabetes groups than in the FBG of < 5.00 mmol/L, group. Conclusions These findings suggest that FBG of 5.55–6.05 mmol/L and FBG of 6.11–6.94 mmol/L are similarly associated with endothelial dysfunction and that a pre-IFG state (FBG of 5.27–5.50 mmol/L) is also a risk for endothelial dysfunction compared with FBG of < 5.00 mmol/L. Clinical Trial Registry Information: http://www.umin.ac.jp (UMIN000012950, UMIN000012951, UMIN000012952, and UMIN000003409)

scholarly journals Glycemic control in diabetes mellitus in patients assisted by a university hospital in the state of Piauí (Brazil)

2020 ◽  
Vol 11 (4) ◽  
pp. 505
Author(s):  
Jose A. NERY-NETO ◽  
Andrew O. SANTOS ◽  
Larissa C. SILVA ◽  
Elison C. HOLANDA ◽  
Maria C. BRITO ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glycemic Control ◽  
Medical Records ◽  
Fasting Glucose ◽  
Statistical Significance ◽  
Fasting Blood Glucose ◽  
University Hospital ◽  
Postprandial Blood Glucose ◽  
Glucose Measurement

Objectives: To investigate glycemic control in outpatient clinics at a university hospital, as well as to correlate HbA1c with fasting glucose and post-prandial glycemia, in order to assess which variable best correlates with an HbA1c. Methods: This is a descriptive cross-sectional study, with data that were collected from electronic medical records, from the random consultation of the medical of the blood glucose measurement. To check glycemic control, the parameters defined by the Brazilian Diabetes Society (2017-2018) were used: fasting glucose <100 mg / dL, HbA1c <7% and postprandial glucose <160 mg / dL. A statistical analysis was performed with the aid of the SPSS® program (version 13.0), adopting p <0.05 as the level of statistical significance. Results: 250 medical records were applied, with the average age of the participants being 60.1 ± 12.9 years (87 men and 163 women). A fasting glycemia was altered beyond the recommended in 80.8% of the individuals evaluated, HbA1c in 45.2% of the cases and 66% of the participants in the study possessed postprandial glycemia in addition to the recommended goals. The correlation between HbA1c/fasting blood glucose (rs= 0.74) and HbA1c/postprandial blood glucose (rs = 0.60) was, respectively, strong and moderate. Conclusions: With this study, it was possible to verify that a significant portion of the limits of use did not have good glycemic control. The correlation between fasting glucose and HbA1c confirmed that HbA1c is the best parameter for monitoring blood glucose levels in diabetes mellitus. In addition, the fasting blood glucose / HbA1c correlation showed greater strength in the postprandial blood glucose / HbA1c correlation.

scholarly journals The positive association between serum uric acid, impaired fasting glucose, impaired glucose tolerance, and diabetes mellitus in the ELSA-Brasil study

2021 ◽  
Vol 37 (9) ◽  
Author(s):  
Aline Isabel Rodrigues Galvão ◽  
Alline Maria R. Beleigoli ◽  
Pedro Guatimosim Vidigal ◽  
Bruce Bartholow Duncan ◽  
Maria Inês Schmidt ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Uric Acid ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Serum Uric Acid ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Newly Diagnosed ◽  
Glycemic Status

Abstract: There is a conflict in the literature regarding the association between serum uric acid (SUA) levels and glycemic status. Therefore, we evaluated the association between SUA level and glycemic status - impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes mellitus - and insulin resistance, in a large Brazilian study. This is a cross-sectional, observational study with 13,207 participants aged 35-74 years, at baseline (2008-2010) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). A multinomial regression analysis was performed to test the association between SUA and glycemic status (IFG, IGT, and newly diagnosed type 2 diabetes at the cohort baseline) after adjustments by age, sex, skin color, body mass index, physical activity, smoking, alcohol consumption, comorbidities, and medicines use. Logistic regression model was used to evaluate the association between SUA and insulin resistance by HOMA-IR. Stratified analyses by sex were performed. The mean age (standard deviation) was 51.4 (8.9) years, 55.2% of participants were women. There were 1,439 newly diagnosed diabetes. After all adjustments, higher SUA was associated with IFG, IGT, and diabetes, with odds ratio (OR) = 1.15 (95%CI: 1.06; 1.25), 1.23 (95%CI: 1.14; 1.33), and 1.37 (95%CI: 1.24; 1.51), respectively. There was association between SUA levels and insulin resistance with OR = 1.24 (95%CI: 1.13; 1.36). In analysis stratified by sex, higher SUA persisted independently associated with impaired glycemic status. Our results suggest that a higher SUA levels were significantly associated with glycemic status in a large Latin American population, mainly among women.

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