scholarly journals Clinical Evaluation of Efficacy of Ayurvedic Management of Jalodara W.S.R. to Tuberculosis induce Ascites: A Case Report

2019 ◽  
Vol 7 (01) ◽  
Author(s):  
Hemlata Soni ◽  
Kartar singh Bansal
Keyword(s):  
Infectious Disease ◽  
Case Report ◽  
Clinical Evaluation ◽  
Older Patients ◽  
Specific Treatment ◽  
Gastrointestinal Involvement ◽  
Pulmonary Tb ◽  
Oral Medications ◽  
Tb Treatment ◽  
Extra Pulmonary

 Tuberculosis (TB) is a serious infectious disease. The diagnosis of TB is a challenge among older patients because of its nonspecific presentation, especially for cases of extra pulmonary TB.  Gastrointestinal involvement had been reported to be 55%-90% in patients with active pulmonary TB before the advent of specific anti-TB treatment. But it was regressed to 25% after the development of specific drugs. TB ascites is known as Jalodar or Dakodar in Ayurvedic system. Ayurvedic management for this disease includes oral medications as well as Virechan for specific treatment to reduce accumulation of fluid, as well as treatment to remove the obstruction Ksheerapan for diet regulation plays an important part of management of this diseases. The present case is uncomplicated tuberculosis induce ascites since 6 month. Patient was treated with “Punarnava Mandura” (250gm), “Gudadraka Yoga” (6gm), “Pippali Vardhman Rasayan” (1to5gm) and “Arand Tail” (25ml) for 30days. The patient got relief from after 7 days of treatment.

scholarly journals A TREATMENT DILEMMA CONCERNING IMMUNOSUPPRESSANT USE: A CASE REPORT

2017 ◽  
Vol 10 (10) ◽  
pp. 4 ◽  
Author(s):  
Madathil Shinu Mary Iype ◽  
Akhilesh Kunoor ◽  
Anila Kn
Keyword(s):  
Case Report ◽  
Causality Assessment ◽  
Safety Concern ◽  
Infectious Complications ◽  
Typical Case ◽  
Pulmonary Tb ◽  
Tb Treatment ◽  
Increased Risk ◽  
Extra Pulmonary

 Immunosuppressants including corticosteroids (prednisolone >15 mg/day) are responsible for an increased risk of susceptibility to infections (especially pneumonia, tuberculosis [TB] including extra pulmonary TB), an important safety concern when providing immunosuppressive therapy. Anti-TB treatment (ATT) is medicines used to treat tuberculosis, an infectious disease which can affect lungs and other organs. Isoniazid, rifampicin, and pyrazinamide are known to cause ATT induced hepatitis. The prevalence of immunosuppressant induced TB and pyrazinamide induced hepatotoxicity during treatment for active TB ranges to about 0.6%-1% and <1%, respectively. Here, we illustrate a typical case report of a 61-year-old woman who is a known case of interstitial lung disease and developed TB arthritis following therapy with the long-term use of immunosuppressants (prednisolone, azathioprine, leflunomide, and sulfasalazine). ATT regimen was started for TB arthritis which was later modified along with addition of liver protectant due to the development of hepatotoxicity. The causality of both the adverse drug reactions was confirmed to be probable via NARANJO causality assessment scale. This case highlights the incidence of infectious complications like TB which may be expected to be encountered more frequently in the future due to the increasing use of immunosuppressants for the treatment of allergic and inflammatory disorders.

RARE PRESENTATION OF EXTRA PULMONARY TB AS MULTIPLE INTRA CRANIAL TUBERCULOMAS- A CASE REPORT

2021 ◽  
pp. 64-65
Author(s):  
M.Azra Tabassum ◽  
Nisar Ahamad Basha ◽  
M. Rama Devi
Keyword(s):  
Case Report ◽  
Neck Pain ◽  
Clinical Improvement ◽  
Hematogenous Spread ◽  
Rare Presentation ◽  
Pulmonary Tb ◽  
Mri Brain ◽  
Spinal Arachnoiditis ◽  
Extra Pulmonary ◽  
Anti Tubercular Therapy

TB of CNS is an uncommon yet highly devastating manifestation of TB. It has a hematogenous spread manifesting as meningitis, cerebritis,TB abscess, Tuberculomas and spinal arachnoiditis. We are reporting a case of 26yr old female person presented with short duration of headache, vomiting, neck pain and altered sensorium .Examination revealed left eye Ptosis and right sided classical hemiplegia . Investigations revealed multiple intracranial tuberculomas in MRI brain and feautures suggestive of miliary TB on CTchest . Multiple tuberculomas are rare presentation of intracranial TB and prognosis is poor in patients with multiple tuberculomas . But in our case clinical improvement is observed with Anti Tubercular Therapy

scholarly journals Multidrug resistant tuberculous meningitis in pregnancy: a rare case report

2019 ◽  
Vol 8 (4) ◽  
pp. 1692
Author(s):  
U. Nagashree ◽  
Charumathi . ◽  
U. Meenakshisundaram
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Extrapulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Pulmonary Tb ◽  
Foetal Growth ◽  
Rare Case Report ◽  
Surgical Options ◽  
Extra Pulmonary ◽  
Tuberculosis Meningitis

The prevalence of tuberculosis, especially extrapulmonary tuberculosis is increasing worldwide. TB meningitis is one of severe manifestations of extra pulmonary TB. Prognosis of cases of multidrug resistance tuberculosis meningitis is worse and even more challenging in pregnant women. It’s mostly associated with increased frequency of maternal disability, hospitalisation during pregnancy, foetal growth retardation, prematurity, low-birth weight and increased perinatal mortality. As information on outcome of pregnancy among women with extra pulmonary TB is limited; various medical and surgical options for timely management has been discussed. Authors bring out a case report of a primigravida at 26 weeks gestation with severe multidrug resistant TB meningitis who was successfully managed at our hospital with a healthy infant. 

scholarly journals Severe Acute Respiratory Syndrome-coronavirus 2 Interstitial Bilateral Pneumonia: A Case Report and Review of Literature

2020 ◽  
Vol 8 (T1) ◽  
pp. 229-232
Author(s):  
Danilo Coco ◽  
Silvana Leanza
Keyword(s):  
Infectious Disease ◽  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Clinical Picture ◽  
Older Patients ◽  
Morbidity And Mortality ◽  
Review Of Literature ◽  
Number Of Patients ◽  
The Usa ◽  
Novel Virus

In December 2019, novel cases of pneumonia were reported for the 1st time in Wuhan, Hubei, China. A novel virus of the big family of coronavirus (COV) was identified as the pathogen, which causes severe acute respiratory syndrome (SARS). The disease is called COV Disease-19 and then SARS-COV 2. The infectious disease has spread worldwide with major number of patients in China, Italy, Spain, France, and the USA. On March 11, 2020, the WHO declared the outbreak of SARS-CoV-2 a pandemic. Morbidity and mortality of the disease cannot yet estimate but have already seen that lethality appears to be particularly higher in older patients. The aim of this article is to present a characteristic clinical picture as case report SARS-COV 2 pneumonia and to provide an overview of the existing literature.

scholarly journals Pericostal tuberculosis in a patient with systemic sclerosis：the relationship of two rare diseases

2021 ◽  
Author(s):  
Naoho Takizawa ◽  
Tetsushi Mizutani ◽  
Yoshiro Fujita
Keyword(s):  
Case Report ◽  
Systemic Sclerosis ◽  
Autoimmune Disease ◽  
Autoimmune Diseases ◽  
Rare Diseases ◽  
Rare Presentation ◽  
Pulmonary Tb ◽  
Increase Risk ◽  
Extra Pulmonary ◽  
Relationship Of

Autoimmune diseases including systemic sclerosis (SSc) increase risk of developing TB. Pericostal tuberculosis (TB) is a rare presentation of skeletal TB. This case report describes pericostal TB in a SSc patient, and emphasizes significance of suspecting pulmonary and extra-pulmonary TB when patients with autoimmune disease follow atypical clinical courses.

To be or not to be hospitalised with tuberculosis in Portugal

2019 ◽  
Vol 23 (9) ◽  
pp. 1029-1034
Author(s):  
M. A. Galego ◽  
J. V. Santos ◽  
J. Viana ◽  
A. Freitas ◽  
R. Duarte
Keyword(s):  
Chronic Diseases ◽  
Data Extraction ◽  
Risk Groups ◽  
Hospitalisation Rate ◽  
Pulmonary Tb ◽  
Tb Treatment ◽  
Hospitalised Patients ◽  
Cavitary Disease ◽  
Extra Pulmonary ◽  
National Databases

SETTING: In Portugal, as in other countries, tuberculosis (TB) is considered a disease that should be managed on an ambulatory basis. However, hospitalisation remains important to manage some at-risk groups and complications.OBJECTIVE: To identify the possible risk factors associated with hospitalisations in TB patients in Portugal.DESIGN: Data extraction through two national databases (one for registration of TB cases and the other with hospitalisation information in public health facilities) between 2007 and 2013. Univariate and multivariate analysis of demographic and clinical variables was performed.RESULTS: We identified 4421 hospitalisations. Chronic diseases, cancer, substance abuse, a higher social/economic risk, extra-pulmonary TB, lung cavitary disease and previous uncompleted treatment were more frequent among hospitalised patients. Human immunodeficiency virus coinfection, cancer, alcohol abuse, extra-pulmonary TB and uncompleted previous TB treatment were the most important predictors of hospitalisation with TB. The hospitalisation rate among TB patients in Portugal was lower when compared with other countries with lower and higher incidences.CONCLUSION: Immune dysfunctions and progression of chronic diseases are associated with more severe forms of TB and frequent adverse effects which can be sufficiently severe to necessitate hospital admission. Despite having an intermediate TB incidence, the hospitalisation rate in Portugal is not higher than that of other countries.

scholarly journals Incidence and predictors of death among adult patients treated for tuberculosis in two regions of Cameroon: 2010 to 2015

2022 ◽  
Vol 0 ◽  
pp. 1-8
Author(s):  
Adamou Dodo Balkissou ◽  
Eric Walter Pefura-Yone ◽  
Virginie Poka ◽  
Alain Kuaban ◽  
Djibril Mohammadou Mubarak ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Regression Models ◽  
Cox Regression ◽  
Western Region ◽  
Pulmonary Tb ◽  
Tb Treatment ◽  
Hazard Ratios ◽  
Immunodeficiency Virus ◽  
Northern Regions ◽  
Extra Pulmonary

Objectives: Mortality during tuberculosis (TB) remains high in Africa. The purpose of our study was to determine the incidence and predictors of death during TB treatment in Cameroon. Materials and Methods: Data of subjects aged ≥15 years were retrospectively extracted from registers in all TB diagnostic and treatment centers in the Western and Northern regions of Cameroon from 2010 to 2015. Cox regression models were used to determine predictors of death during TB treatment. Results: Of the 19,681 patients included, 12,541 (63.7%) were male and their median age (25th-75th percentile) was 34 (26–45) years. The cumulative incidence (95% confidence interval [CI]) of death during TB treatment was 8.0% (7.5–8.5%). The predictors (hazard ratios [95% CI]) of death were: Age >34 years (1.479 [1.295–1.688], P < 0.001), female sex (1.471 [1.286–1.683], P < 0.001), extra-pulmonary TB (1.723 [1.466–2.026], P < 0.001), human immunodeficiency virus infection (3.739 [3.269–4.276], P < 001]), TB treatment in the Western region (2.241 [1.815–2.768], P < 0.001), treatment before 2012 (1.215 [1.073–1.376], P = 0.002)and low body weight (1st quartile and 2nd quartile) (2.568 [2.133–3.092], [P < 0.001]) and (1.569 [1.298–1.896], P < 0.001) respectively. Conclusion: The incidence of death during TB was relatively high in the Western and Northern regions of Cameroon. Recognition of these persons at greatest risk may improve care and reduce death durinng TB treatment.

scholarly journals Tuberculous Lymphadenitis: Early Diagnosis by GeneXpert of an Auramine-Negative Case

2020 ◽  
Vol 3 (1) ◽  
pp. 108-110
Author(s):  
Louise Munezero ◽  
Narcisse Niyikora ◽  
Fidèle Mahirane ◽  
Belson Rugwizangoga
Keyword(s):  
Public Health ◽  
Mycobacterium Tuberculosis ◽  
Early Diagnosis ◽  
Key Words ◽  
Tuberculous Lymphadenitis ◽  
Pulmonary Tb ◽  
Tb Treatment ◽  
Negative Case ◽  
Extra Pulmonary ◽  
The Right

Tuberculosis (TB) remains one of the major public health problems with a considerable number of new cases. Tuberculous lymphadenitis is one of the most common forms of extra-pulmonary TB whose diagnosis still faces many challenges. The case to report is a 17-year old female patient with a painful swelling in her right infra-retro-auricular area and the auramine stain was negative for acid-fast bacilli (AFB). GeneXpert was done, which confirmed the right infra-retro-auricular tuberculous lymphadenitis. The patient responded well to anti-TB treatment. Key words: Lymphadenitis; Mycobacterium tuberculosis; Auramine; GeneXpert

Poncet’s Disease: A Case Report

2020 ◽  
Author(s):  
Henuka Verma ◽  
Nikhil Rajvanshi ◽  
Vyas Kumar Rathaur ◽  
Monika Pathania ◽  
Nowneet Kumar Bhat
Keyword(s):  
Infectious Disease ◽  
Differential Diagnosis ◽  
Case Report ◽  
Joint Pain ◽  
Organ System ◽  
X Rays ◽  
Separate Entity ◽  
Pulmonary Tb ◽  
System Diagnosis ◽  
Poncet’S Disease

Abstract Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB). It spreads from one person to the another through the air while coughing, spitting, speaking or sneezing. TB most commonly affects lungs but it can affect any organ system. Diagnosis of TB is made on the basis of microbiological evidence of MTB on microscopic examination, cultures and chest X-rays. Poncet’s disease is a separate entity in which joints are involved in the form of joint pain and swelling without any microbiological evidence of MTB. It usually occurs in the background setting of pulmonary TB. This case focuses on importance of considering Poncet’s disease in the differential diagnosis of paediatric polyarticular arthritis in TB endemic regions or if there is a history suggestive of TB exposure and infection.

Anti-tubercular activity of some six membered heterocycle compounds

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Infectious Disease ◽  
Cell Wall ◽  
Latent Tuberculosis ◽  
Drug Resistant ◽  
Significant Development ◽  
Tb Treatment ◽  
Modern Drug ◽  
Mycobacterial Cell Wall ◽  
Membered Heterocycle ◽  
New Chemical Entity

The effectiveness in TB treatment is difficult because the structural composition of the mycobacterial cell wall is very complicated, which makes many drugs ineffective. Tuberculosis is still one of the most imperative infectious disease worldwide becouse its important reason is drug resistant, persistent or latent tuberculosis and synergism with HIV. Furthermore no any new chemical entity has come. The recently application of modern drug design promise to bring significant development in the fight against TB. In present review we discussed brief introduction of tuberculosis.

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