scholarly journals Researches done on Extra pharmacopoeial drugs (Anukta Dravyas) belonging to Terminalia Genus – A systematic review and Meta-analysis.

1970 ◽  
Vol 7 (4) ◽  
Author(s):  
Neha Gaonkar
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Research Work ◽  
Therapeutic Agents ◽  
Indian Species ◽  
Terminalia Chebula ◽  
Anticancer Activities ◽  
Medicinal Uses ◽  
Anti Oxidant ◽  
Medicinal Properties

The aim of this work was to systematically review and Meta-analyze the researches done on extra pharmacopoeial drugs (anukta dravyas) belonging to Terminalia genus. Terminalia is the second largest genus of family Combrataceae. Plants of the genus Terminalia are amongst the most widely used plants for traditional medicinal purposes worldwide. Many species are used for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, anti oxidant, anti inflammatory and anticancer activities. Indeed, the Indian species Terminalia chebula is known as the king of plants in Ayurveda due to its broad range of medicinal uses. However, apart from the reported ethnopharmacological uses of many Terminalia species, surprisingly few studies have rigorously examined this important genus for their medical properties/mechanisms. The last decade has seen a large increase in the number of studies into the use of Terminalia species as therapeutic agents. Data collected till 2018, showed around 120 different databases, articles and researches done on medicinal properties of plants belonging to Terminalia species. It was observed that out of the 250 species of Terminalia genus, research work of 80 plants was done which claimed their potential as medicines.

scholarly journals Traditional uses, phytochemistry, pharmacology and toxicity of Arisaema (Areaceae): a review

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Heena Ali ◽  
Ubaid Yaqoob
Keyword(s):  
Skin Irritation ◽  
Clinical Applications ◽  
Human Populations ◽  
Main Body ◽  
Anticancer Activities ◽  
Medicinal Uses ◽  
The World ◽  
Different Types ◽  
Tropical Areas ◽  
Medicinal Properties

Abstract Background The genus Arisaema (Areaceae), popularly known as cobra lilies and jack in pulpit is mainly found in temperate to tropical areas of all continents except South America, Europe and Australia and contain about more than 250 species. Arisaema genus is being used by the different folks of human populations for medicinal as well as food purposes. Arisaema plants are used for the treatment of different types of diseases. There have been several attempts to highlight different aspects of genus Arisaema by describing it in terms of phytochemistry and medicinal uses. The present study is, however, an attempt to put together all the former data available related to the phytochemistry and medicinal uses of genus Arisaema. Main body The phytochemicals of the plant include alkaloids, phenols, terpenes, flavonoids, lectins, saponins, glycosides, triterpenoids, stigmasterols, n-alkanes, n-alkanols sitosterols, campesterol, oxalates, coumarins, tannins etc. Moreover, the properties such as antioxidant, antifungal, antibacterial, insecticidal, antimicrobial, cytotoxic, nematocidal, antiallergic antitumour and anticancer activities are also shown by the plants belonging to genus Arisaema. Arisaema plants have been traditionally used to treat various ailments such as resolving phlegm, dampness, and to treat asthma, bronchitis, cold, cough, and laryngitis etc. It has been found that there are several species which are toxic by nature. The development of clinical applications of arisaematis rhizomes had been seriously constrained due to its toxic properties like, mouth and lingua pain, even respiration slowing and suffocation, mucous membrane and skin irritation etc. and this toxicity of arisaematis rhizomes is due to raphide components. Conclusions The collection of data available on the phytochemistry of genus Arisaema is not sufficient as further work is required to do on phytochemical and medicinal basis. The data available on phytochemistry and medicinal properties of the plants belonging to genus Arisaema throws light on various species of Arisaema which are medicinally important and have been exploited to treat different types of diseases in the world.

scholarly journals The effect of unilateral and bilateral laparoscopic surgery for endometriosis on Anti-Mullerian Hormone (AMH) level after 3 and 6 months: a systematic review and meta-analysis

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Anisodowleh Nankali ◽  
Mohsen Kazeminia ◽  
Parnian Kord Jamshidi ◽  
Shamarina Shohaimi ◽  
Nader Salari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Laparoscopic Surgery ◽  
Growth Factors ◽  
Web Of Science ◽  
Meta Analysis ◽  
Research Work ◽  
Mean Difference ◽  
Transient Growth ◽  
Common Causes ◽  
Standardized Mean Difference

Abstract Background Endometriosis is one of the most common causes of infertility. The causes of the disease and its definitive treatments are still unclear. Moreover, Anti-Mullerian Hormone (AMH) is a glycoprotein dimer that is a member of the transient growth factors family. This research work aimed to identify the effect of unilateral and bilateral laparoscopic surgery for endometriosis on AMH levels after 3 months, and 6 months, using meta-analysis. Methods In this study, the articles published in national and international databases of SID, MagIran, IranMedex, IranDoc, Cochrane, Embase, Science Direct, Scopus, PubMed, and Web of Science (ISI) were searched to find electronically published studies between 2010 and 2019. The heterogeneous index between studies was determined using the I2 index. Results In this meta-analysis and systematic review, 19 articles were eligible for inclusion in the study. The standardized mean difference was obtained in examining of unilateral laparoscopic surgery for endometriosis (before intervention 2.8 ± 0.11, and after 3 months 2.05 ± 0.13; and before intervention 3.1 ± 0.46 and after 6 months 2.08 ± 0.31), and in examining bilateral laparoscopic surgery for endometriosis examination (before intervention 2.0 ± 08.08, and after 3 months 1.1 ± 0.1; and before intervention 2.9 ± 0.23 and after 6 months 1.4 ± 0.19). Conclusion The results of this study demonstrate that unilateral and bilateral laparoscopic surgery for endometriosis is effective on AMH levels, and the level decreases in both comparisons.

scholarly journals The prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients: a systematic review and meta-regression

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Nader Salari ◽  
Habibolah Khazaie ◽  
Amin Hosseinian-Far ◽  
Behnam Khaledi-Paveh ◽  
Mohsen Kazeminia ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sample Size ◽  
Healthcare Workers ◽  
Meta Analysis ◽  
Research Work ◽  
Hospital Staff ◽  
Anxiety And Depression ◽  
Front Line ◽  
Prevalence Of Depression ◽  
Meta Regression

Abstract Background Stress, anxiety, and depression are some of the most important research and practice challenges for psychologists, psychiatrists, and behavioral scientists. Due to the importance of issue and the lack of general statistics on these disorders among the Hospital staff treating the COVID-19 patients, this study aims to systematically review and determine the prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients. Methods In this research work, the systematic review, meta-analysis and meta-regression approaches are used to approximate the prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients. The keywords of prevalence, anxiety, stress, depression, psychopathy, mental illness, mental disorder, doctor, physician, nurse, hospital staff, 2019-nCoV, COVID-19, SARS-CoV-2 and Coronaviruses were used for searching the SID, MagIran, IranMedex, IranDoc, ScienceDirect, Embase, Scopus, PubMed, Web of Science (ISI) and Google Scholar databases. The search process was conducted in December 2019 to June 2020. In order to amalgamate and analyze the reported results within the collected studies, the random effects model is used. The heterogeneity of the studies is assessed using the I2 index. Lastly, the data analysis is performed within the Comprehensive Meta-Analysis software. Results Of the 29 studies with a total sample size of 22,380, 21 papers have reported the prevalence of depression, 23 have reported the prevalence of anxiety, and 9 studies have reported the prevalence of stress. The prevalence of depression is 24.3% (18% CI 18.2–31.6%), the prevalence of anxiety is 25.8% (95% CI 20.5–31.9%), and the prevalence of stress is 45% (95% CI 24.3–67.5%) among the hospitals’ Hospital staff caring for the COVID-19 patients. According to the results of meta-regression analysis, with increasing the sample size, the prevalence of depression and anxiety decreased, and this was statistically significant (P < 0.05), however, the prevalence of stress increased with increasing the sample size, yet this was not statistically significant (P = 0.829). Conclusion The results of this study clearly demonstrate that the prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients is high. Therefore, the health policy-makers should take measures to control and prevent mental disorders in the Hospital staff.

Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography: an updated and comprehensive meta-analysis and systematic review

2016 ◽  
pp. 610-626 ◽  
Author(s):  
Sadeq Ali-Hasan-Al-Saegh ◽  
Seyed Jalil Mirhosseini ◽  
Zahra Ghodratipour ◽  
Zahra Sarafan-Chaharsoughi ◽  
Ali Mohammad Dehghan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Coronary Angiography ◽  
Meta Analysis ◽  
Protective Effects ◽  
Contrast Induced Nephropathy ◽  
Anti Oxidant

Selected root plant supplementation reduces indices of exercise-induced muscle damage: A systematic review and meta-analysis

2020 ◽  
pp. 1-21
Author(s):  
Kenji Doma ◽  
Baily Devantier-Thomas ◽  
Daniel Gahreman ◽  
Jonathan Connor
Keyword(s):  
Oxidative Stress ◽  
Systematic Review ◽  
Muscle Damage ◽  
Performance Measures ◽  
Muscle Soreness ◽  
Meta Analysis ◽  
Muscular Performance ◽  
Anti Oxidant ◽  
Exercise Induced ◽  
Oxidant Status

Abstract. This systematic review and meta-analysis examined the effects of selected root plants (curcumin, ginseng, ginger and garlic) on markers of muscle damage and muscular performance measures following muscle-damaging protocols. We included 25 studies (parallel and crossover design) with 353 participants and used the PEDro scale to appraise each study. Forest plots were generated to report on standardised mean differences (SMD) and p-values at 24 and 48 hours following the muscle-damaging protocols. The meta-analysis showed that the supplemental (SUPP) condition showed significantly lower levels of indirect muscle damage markers (creatine kinase, lactate dehydrogenase and myoglobin) and muscle soreness at 24 hours and 48 hours (p < 0.01) than the placebo (PLA) condition. The inflammatory markers were significantly lower for the SUPP condition than the PLA condition at 24 hours (p = 0.02), although no differences were identified at 48 hours (p = 0.40). There were no significant differences in muscular performance measures between the SUPP and PLA conditions at 24 hours and 48 hours (p > 0.05) post-exercise. According to our qualitative data, a number of studies reported a reduction in oxidative stress (e.g., malondialdehyde, superoxide dismutase) with a concomitant upregulation of anti-oxidant status, although other studies showed no effects. Accordingly, selected root plants minimised the level of several biomarkers of muscle damage, inflammation and muscle soreness during periods of exercise-induced muscle damage. However, the benefits of these supplements in ameliorating oxidative stress, increasing anti-oxidant status and accelerating recovery of muscular performance appears equivocal, warranting further research in these outcome measures.

scholarly journals A systematic review and meta-analysis on correlation of weather with COVID-19

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Poulami Majumder ◽  
Partha Pratim Ray
Keyword(s):  
Systematic Review ◽  
Wind Speed ◽  
Death Rate ◽  
Meta Analysis ◽  
Research Work ◽  
Ultra Violet ◽  
Fixed Effect ◽  
Data Set ◽  
Ultra Violet Radiation ◽  
Weather Parameters

AbstractThis study presents a systematic review and meta-analysis over the findings of significance of correlations between weather parameters (temperature, humidity, rainfall, ultra violet radiation, wind speed) and COVID-19. The meta-analysis was performed by using ‘meta’ package in R studio. We found significant correlation between temperature (0.11 [95% CI 0.01–0.22], 0.22 [95% CI, 0.16–0.28] for fixed effect death rate and incidence, respectively), humidity (0.14 [95% CI 0.07–0.20] for fixed effect incidence) and wind speed (0.58 [95% CI 0.49–0.66] for fixed effect incidence) with the death rate and incidence of COVID-19 (p < 0.01). The study included 11 articles that carried extensive research work on more than 110 country-wise data set. Thus, we can show that weather can be considered as an important element regarding the correlation with COVID-19.

scholarly journals Ethno-Botanical Survey on Traditional and Medicinal Uses of Leguminosae Family at Rajnandgaon and Balod District of Chhattisgarh

2021 ◽  
Vol 9 (VII) ◽  
pp. 2215-2223
Author(s):  
Rakesh Kumar
Keyword(s):  
Urban Communities ◽  
Plant Species ◽  
Rural Areas ◽  
Research Work ◽  
Rare Plants ◽  
Local Health ◽  
Botanical Survey ◽  
Medicinal Uses ◽  
The Family ◽  
Medicinal Properties

Leguminosae is one of the largest family with three sub-families and it has a great ethno-botanical and ethno-medicinal importance in indigenous and urban communities throughout the Chhattisgarh. Leguminous plants are widely used for many purposes by peoples of rural areas and it includes many important cultivated economic food crops. The research work was initiated to get information and reports the traditional and medicinal uses of the family leguminosae by tribal peoples of Chhattisgarh. The paper also deals with an account of endemic and rare plants of Leguminosae existence of Chhattisgarh. In our field survey we got 3 rare plants species Alysicarpus bupleurifolicus, Flemingia stricta,and Zornia gibbosa belonging to Papilionatae sub-family. They had highly medicinal properties that’s why their more exploitation done by tribal people and get become a rare plant species which is also included in BSI report of endemic and rare plants of Chhattisgarh 2004. A total of 63 medicinal plant species are used by the local health healer for the treatment of different disease. The medicinal plants used by the traditional users of Rajnandgaon and Balod district are arranged alphabetically followed by botanical name, common name, flowering time, habit and their uses.

scholarly journals A comprehensive review on physicochemical, pharmacological and analytical profile of curcumin

2021 ◽  
Vol 12 (2) ◽  
pp. 987-998
Author(s):  
Kavita Rohilla ◽  
Sunita ahlawat ◽  
Manjusha Choudhary ◽  
Vikas Budhwar
Keyword(s):  
Curcuma Longa ◽  
Aqueous Solubility ◽  
Present Review ◽  
Medicinal Uses ◽  
Anti Oxidant ◽  
Low Toxicity ◽  
Ancient Times ◽  
Medicinal Properties ◽  
Higher Doses ◽  
Anti Hiv

In the rhizomes of curcuma longa (family zinziberaceae), curcumin is present as a pigment, due to which it has importance in spices, cosmetics and drugs. It shows a variety of biological and physiological activities, like anti-tumour, anti-inflammatory, antiviral, anti-oxidant, anti-HIV etc. It has low toxicity at higher doses and is well tolerated by the human body. In spite of the proven research that supports the medicinal benefits of curcumin, its medicinal uses are countered by its low aqueous solubility and potential to get degraded in the GIT, which ultimately contributes towards its poor bioavailability. The present review summarizes the uses and applications of curcumin in drugs and cosmetics, briefly describing its status in folk medicines. It also mentions the methods of its analysis in drugs and cosmetics formulations and foodstuffs. The use of turmeric in ayurvedic medicines is described with their recipe and references. From the ancient times, turmeric is being used in various cosmetic preparations. In Indian rituals, turmeric is an essential component. In this review, various uses of the turmeric in cosmetics is mentioned. Ongoing recent research in these spheres is also summarised with references. In this review, the drawbacks of curcumin are also mentioned. As we know that turmeric is an ancient herb and have very beneficial properties beside this, it has some drawbacks, some negative properties etc. In the present review, we have discussed about various pharmacological, pharmacokinetic and medicinal properties of the curcumin and all this is summarized with the help of text, tables and figures. Various historical researches about curcumin are mentioned, including information about the discovery. 

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

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