Speechless

Author(s):  
Rida Bashir

This paper sets out fromthe understanding that empowerment is a process by which those who have been denied power gain power, in particular the ability to make strategic life choices. For women, these could be the capacity to choose a marriage partner, a livelihood, or whether or not to have children. For this power to come about, three interrelated dimensions are needed: access to and control of resources; agency (the ability to use these resources to bring about new opportunities) and achievements (the attainment of new social outcomes). Empowerment, therefore, is both a process and an end result. This understanding differs greatly from instrumentalist interpretations which view empowerment purely in terms of measurable outcomes. Instrumentalist interpretations are problematic because they convey the belief that social change can be predicted and prescribed in a cause-and-effect way and undermine the notion that women’s empowerment should be about the ability of women to make self-determined choices. Third World countries are increasingly forced to rely on internal resource mobilization to make up for sharp reductions in external aid and resources. Alongside this, development processes are often indifferent to the interests and needs of the poor. In this scenario, women’s contributions as workers and as managers of human welfare-are central to the ability of households, communities, and nations to tackle the resulting crisis. However, women suffer from decreased access to resources and increased demands on their labor and time. If human survival is the world’s most pressing problem, and if women are crucial to that survival, then the empowerment of women is essential for the emergence of new, creative, and cooperative solutions. As part of the empowerment process, feminism and collective action are fundamental but feminism must not be monolithic in its issues, goals, and strategies, since it should constitute the political expression of the concerns and interests of women from different regions, classes, nationalities, and ethnic backgrounds. There is and must be a diversity of feminisms, responsive to the different needs and concerns of different women and defined by women for themselves. The underlying foundation to this diversity is the common opposition to gender oppression and other forms of domination. In the ongoing United Nations debate on human rights and sexuality, sexual rights have been conceptualizedin largely negative ways in relation to issues of protection against pregnancy, rape, disease, and violence. This paper calls for an inclusion of more positive aspects of sexual rights.

1983 ◽  
Vol 9 (4) ◽  
pp. 235-249 ◽  
Author(s):  
Stephen D. Krasner

What do Third World countries want? More wealth. How can they get it? By adopting more economically rational policies. What should the North do? Facilitate these policies. How should the North approach global negotiations? With cautious optimism. What is the long term prognosis for North–South relations? Hopeful, at least if economic development occurs. This is the common wisdom about relations between industrialized and developing areas in the United States and much of the rest of the North, Within this fold there are intense debates among adherents of conventional liberal, reformist liberal, and interdependence viewpoints. But the emphasis on economics at the expense of politics, on material well-being as opposed to power and control, pervades all of these orientations.


Quality insurance creates a leverage effect in the global market competition, in particular for software development processes. Thus, companies are brought to use several standards and benchmarks of good practices in management and control of information systems. However, implementing several standards within the same company is difficult and time consuming. In this paper, we propose a Model Driven Engineering approach of building a common repository. It is focused on the common metamodel building. The transformation rules are formalized and illustrated by CMMI model.


2018 ◽  
Vol 28 (1) ◽  
pp. 137-141
Author(s):  
Petya Yordanova – Dinova

This paper explores the comparative analysis of the financial controlling, who is a result from the common controlling concept and the financial management. In the specialized literature, financial controlling is seen as an innovative approach to financial management. It is often presented as the most promising instrument of financial diagnostics. Generally speaking, financial controlling is seen as a process of managing the company`s assets which are valued in monetary measures. The difference between the financial management and the financial controlling is that the second covers all functions of management, analysis and control of finances, aiming at maximizing their effective use and increasing the value of the enterprise. Financial controlling is often seen as a function of the common practice of financial management. Its objective is to preserve the financial stability and financial sustainability of enterprises operating in a highly aggressive business environment.


2020 ◽  
pp. 120347542098255
Author(s):  
Kayadri Ratnarajah ◽  
Michelle Le ◽  
Anastasiya Muntyanu ◽  
Steve Mathieu ◽  
Simon Nigen ◽  
...  

Dupilumab, a monoclonal antibody against the common receptor of interleukin (IL)-4 and IL-13, was the first biologic therapy approved in Canada for treatment of moderate-to-severe atopic dermatitis (AD). While it is considered safe and effective, dupilumab is not universally effective and 8%-38% of patients develop conjunctivitis, while some patients develop head and neck dermatitis. Thus, new therapeutic options are warranted. While both IL-4 and IL-13 play important roles in the pathogenesis of AD, it has been recently demonstrated that IL-13 is the primary upregulated cytokine in AD skin biopsy samples. A placebo-controlled phase 2b clinical trial evaluating the efficacy and safety of lebrikizumab, an IL-13 inhibitor, in AD demonstrated that, at 16 weeks, Eczema Area and Severity Index (EASI) 75 and Investigator’s Global Assessment (IGA) 0/1 were achieved by 60.6% and 44.6% of patients taking lebrikizumab at its highest dose (vs 24.3% and 15.3% of patients taking placebo, respectively). Moreover, treatment with lebrikizumab was associated with rapid improvement of pruritus and low rates of conjunctivitis (1.4%-3.8%). Another IL-13 monoclonal antibody, tralokinumab, was evaluated for safety and efficacy in moderate-to-severe AD. By week 12, among adults receiving 300 mg tralokinumab, 42.5% achieved EASI-75 and 26.7% achieved IGA 0/1 score (vs 15.5% and 11.8% in the placebo group, respectively). Both lebrikizumab and tralokinumab demonstrated acceptable safety profiles in AD (and non-AD) trials with adverse events often being comparable between treatment and control groups. Thus, IL-13 inhibitors may provide a safe and effective treatment alternative for patients with moderate-to-severe AD.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Thomas Dimpfl ◽  
Dalia Elshiaty

PurposeCryptocurrency markets are notoriously noisy, but not all markets might behave in the exact same way. Therefore, the aim of this paper is to investigate which one of the cryptocurrency markets contributes the most to the common volatility component inherent in the market.Design/methodology/approachThe paper extracts each of the cryptocurrency's markets' latent volatility using a stochastic volatility model and, subsequently, models their dynamics in a fractionally cointegrated vector autoregressive model. The authors use the refinement of Lien and Shrestha (2009, J. Futures Mark) to come up with unique Hasbrouck (1995, J. Finance) information shares.FindingsThe authors’ findings indicate that Bitfinex is the leading market for Bitcoin and Ripple, while Bitstamp dominates for Ethereum and Litecoin. Based on the dominant market for each cryptocurrency, the authors find that the volatility of Bitcoin explains most of the volatility among the different cryptocurrencies.Research limitations/implicationsThe authors’ findings are limited by the availability of the cryptocurrency data. Apart from Bitcoin, the data series for the other cryptocurrencies are not long enough to ensure the precision of the authors’ estimates.Originality/valueTo date, only price discovery in cryptocurrencies has been studied and identified. This paper extends the current literature into the realm of volatility discovery. In addition, the authors propose a discrete version for the evolution of a markets fundamental volatility, extending the work of Dias et al. (2018).


2009 ◽  
pp. 47-65
Author(s):  
Alessandra Dino

Territorial control is one of the most important elements for the survival of the mafia. It is an obligated path to be able to obtain and control economic activities and to penetrate into all profitable sectors. Without territorial control it is impossible to control voters and without it all relationships with politics wither and die. It is within the territory where the imposition of "pizzo" (protection money) and extortion are planned against businesses and firms. This impending presence is also the cause in which citizens and families find themselves submitted to violence, the abuse of power and, if not only, to a limitation to their sphere of action. Telling the story about the scappati is to explain how, by their use of violence, Cosa Nostra has taken away from the State its lawful supremacy over large parts of the national territory. They planned the removal or deportation, under the threat of death, of entire families connected to the mafia. This story began in 1980 and is yet to be finished. The scappati migrated to the usa during the second mafia war and today they would like to come back to Palermo. However, not all agree with this possibility. The Sicilian mafia is in a critical position and if these refugees return it could produce a drastic and unexpected change in its leadership. Reading the pizzini (small notes of mafia members), analysing these sources, reconstructing scenarios makes it is easy to image what could happen if they returned: a new bloody conflict among mafia families.Key words: Cosa Nostra, territorial control, transnational crime, maxi-trial, mafia wars, the scappati.Parole chiave: Cosa nostra, controllo del territorio, crimine transnazionale, maxiprocesso, guerre di mafia, scappati.


2018 ◽  
Vol 27 (4) ◽  
pp. 415-426
Author(s):  
Jay P. Carlson ◽  
Larry D. Compeau

Purpose Prior research has demonstrated that reference prices can affect consumer responses, but the reference prices examined have been presented along with semantic cues [e.g. manufacturer’s suggested retail price (MSRP) and Compare At]. This study is unique in investigating the effects of reference prices that do not include a semantic cue (i.e. “cue-less”) on consumers’ responses. It also studies consumers’ beliefs about factory outlet stores, a seldom-studied store type in which cue-less reference prices are used. Design/methodology/approach One qualitative study and one experiment were carried out in this research. Findings The qualitative study revealed that a price tag including cue-less reference prices was unlikely to be viewed as a seller mistake or with suspicion, but nonetheless did confuse some respondents. The experiment demonstrated that while consumers find cue-less reference prices to be somewhat less believable that high MSRPs, these beliefs do not appear to come into play when consumers judge attractiveness (e.g. perceived value). Additionally, the results suggest that consumers believe that a product available for sale in a factory outlet store is likely to have been previously available at a different type of store. Originality/value This research advances the theory of the effects of reference prices on consumers’ responses by examining the common practice of not labeling reference prices with semantic cues. It also extends the literature regarding consumer beliefs about factory outlet stores.


1987 ◽  
Vol 49 (2) ◽  
pp. 251-273 ◽  
Author(s):  
Joseph H. Carens

Many poor and oppressed people wish to leave their countries of origin in the third world to come to affluent Western societies. This essay argues that there is little justification for keeping them out. The essay draws on three contemporary approaches to political theory — the Rawlsian, the Nozickean, and the utilitarian — to construct arguments for open borders. The fact that all three theories converge upon the same results on this issue, despite their significant disagreements on others, strengthens the case for open borders and reveals its roots in our deep commitment to respect all human beings as free and equal moral persons. The final part of the essay considers communitarian objections to this conclusion, especially those of Michael Walzer.


2003 ◽  
Vol 30 (6) ◽  
pp. 771-788 ◽  
Author(s):  
Jacquie A. Shillis ◽  
Beverly A. Hall ◽  
Gail G. Sneden ◽  
Nell H. Gottlieb

This case study examines a nonlegislative task force as it struggled to reach internal consensus despite external-political constraints. The study highlights the convergence of politics and science, revealing complex issues likely to be confronted by advocates and public health officials. Three themes capture participants’experiences: context, sizing up the opportunities and constraints; task force process, tacit strategy to operate outside the political context and play the science card; and aftermath, a glass half full. The task force took advantage of ambiguous parameters, crafting a comprehensive statewide plan to reduce tobacco use and breaking out of the common public health paradigm of allowing budget considerations to drive program design. These internal victories could not sustain a policy success in the legislature. However, the group’s product sets science-based standards for future program development, and the task force’s process provides valuable insights into other states developing tobacco prevention and control policies.


BMC Genomics ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Inés González-Castellano ◽  
Chiara Manfrin ◽  
Alberto Pallavicini ◽  
Andrés Martínez-Lage

Abstract Background The common littoral shrimp Palaemon serratus is an economically important decapod resource in some European communities. Aquaculture practices prevent the genetic deterioration of wild stocks caused by overfishing and at the same time enhance the production. The biotechnological manipulation of sex-related genes has the proved potential to improve the aquaculture production but the scarcity of genomic data about P. serratus hinders these applications. RNA-Seq analysis has been performed on ovary and testis samples to generate a reference gonadal transcriptome. Differential expression analyses were conducted between three ovary and three testis samples sequenced by Illumina HiSeq 4000 PE100 to reveal sex-related genes with sex-biased or sex-specific expression patterns. Results A total of 224.5 and 281.1 million paired-end reads were produced from ovary and testis samples, respectively. De novo assembly of ovary and testis trimmed reads yielded a transcriptome with 39,186 transcripts. The 29.57% of the transcriptome retrieved at least one annotation and 11,087 differentially expressed genes (DEGs) were detected between ovary and testis replicates. Six thousand two hundred seven genes were up-regulated in ovaries meanwhile 4880 genes were up-regulated in testes. Candidate genes to be involved in sexual development and gonadal development processes were retrieved from the transcriptome. These sex-related genes were discussed taking into account whether they were up-regulated in ovary, up-regulated in testis or not differentially expressed between gonads and in the framework of previous findings in other crustacean species. Conclusions This is the first transcriptome analysis of P. serratus gonads using RNA-Seq technology. Interesting findings about sex-related genes from an evolutionary perspective (such as Dmrt1) and for putative future aquaculture applications (Iag or vitellogenesis genes) are reported here. We provide a valuable dataset that will facilitate further research into the reproductive biology of this shrimp.


Sign in / Sign up

Export Citation Format

Share Document