scholarly journals Meta-analysis on the role of exercise in the treatment of constipation

2021 ◽  
Vol 1 ◽  
pp. 210001
Author(s):  
Thomas Weiser ◽  
Sabine Landes
Keyword(s):  
Exercise Therapy ◽  
Life Style ◽  
Chronic Constipation ◽  
Meta Analysis ◽  
Exercise Programme ◽  
Sodium Picosulfate ◽  
Current Guidelines ◽  
Positive Effect

Current guidelines recommend life-style adjustment (including more exercise) as the first measure for treating constipation. This meta-analysis investigated the influence of exercise therapy on the symptoms of patients with chronic constipation. About half of participants in a exercise programme lasting several weeks experienced a positive effect on their symptoms. Studies with the laxatives bisacodyl and sodium picosulfate showed that these generally alleviated symptoms even within the first day of treatment.

scholarly journals IPR Law Protection and Enforcement and the Effect on Horizontal Productivity Spillovers from Inward FDI to Domestic Firms: A Meta-analysis

2021 ◽  
Author(s):  
Danai Christopoulou ◽  
Nikolaos Papageorgiadis ◽  
Chengang Wang ◽  
Georgios Magkonis
Keyword(s):  
Intellectual Property ◽  
Property Rights ◽  
Intellectual Property Rights ◽  
Meta Analysis ◽  
Host Countries ◽  
Productivity Spillovers ◽  
Domestic Firms ◽  
The Relationship ◽  
Positive Effect

AbstractWe study the role of the strength of Intellectual Property Rights (IPR) law protection and enforcement in influencing horizontal productivity spillovers from inward FDI to domestic firms in host countries. While most WTO countries adopted strong IPR legislation due to exogenous pressure resulting from the signing of the Trade-Related Aspects of IPR (TRIPS) agreement, public IPR enforcement strength continues to vary significantly between countries. We meta-analyse 49 studies and find that public IPR enforcement strength has a direct positive effect on horizontal productivity spillovers from inward FDI to domestic firms and a negative moderating effect on the relationship between IPR law protection strength and horizontal productivity spillovers from inward FDI to domestic firms.

scholarly journals Paracetamol and the Placebo Effect in Osteoarthritis Trials: A Missing Link?

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Henning Zeidler
Keyword(s):  
Placebo Effect ◽  
Rescue Medication ◽  
Meta Analysis ◽  
Symptom Relief ◽  
Placebo Response ◽  
Potential Contribution ◽  
Missing Link ◽  
Starting Dose ◽  
Positive Effect

This paper addresses the role of paracetamol in placebo-controlled osteoarthritis (OA) trials and the potential contribution to the large placebo response in such trials. Paracetamol is used as rescue medication in nearly all OA placebo-controlled trials. Triggered by the discussion about the placebo effect in general and because of the lack of systematic reviews of placebo effect in OA trials, a recent meta-analysis examined the placebo effect and its potential determinants in the treatment of OA, as the main result came out that placebo is very effective in the treatment of OA, especially for pain, stiffness, and self-reported function. However, mostly limited data are available from published OA trials on the starting dose, final dose, dose over time of paracetamol use, and the percentage of patients who used rescue medication during the study. Paracetamol may be an important additional simulated effect of placebo administration mimicking the true placebo effect and thus a missing link contributing partially to the large placebo response in OA trials. Therefore, the positive effect of paracetamol on symptom relief as well as the need for standardized recording of rescue medication should be taken into account when designing, executing, and interpreting placebo-controlled OA studies.

scholarly journals The Role of Public Defenders Within the American Justice System

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Brianna Fisher ◽  
Patti Thompson
Keyword(s):  
Work Ethic ◽  
Meta Analysis ◽  
Effect Sizes ◽  
Weighted Mean ◽  
Public Defenders ◽  
Weighted Means ◽  
Negative Effect ◽  
American Cities ◽  
Positive Effect

This paper examines the inner workings of the legal system in connection with public defenders and their duties. The factors of total caseload, plea deals, waivers, and bench verdicts were implemented to create a comprehensive means of measuring work ethic, due to their significant presence in the everyday workings of public defenders. Through a meta-analysis of the five most densely populated African American cities within the state of Michigan, the combined and individual weighted mean effect sizes were calculated to determine if there was a strong positive or negative effect of the four factors mentioned above on work ethic. Additionally, both the upper and lower credibility levels were calculated to analyze their proximity to the weighted means. For all four factors tested, the weighted mean effect sizes relate a positive effect of the factors on work ethic, with all means falling closer to their upper credibility levels. These results confirm that the factors of total caseload, plea deals, waivers, and bench verdicts affect how cases are being handled and how clients are being treated.

The Role of Information Technology in Learning

2005 ◽  
pp. 14-36 ◽  
Author(s):  
Klarissa T.T. Chang ◽  
John Lim
Keyword(s):  
Information Technology ◽  
Task Performance ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Knowledge Retention ◽  
Research And Practice ◽  
Course Characteristics ◽  
Positive Effect ◽  
Role Of Information

This study provides an updated meta-analysis on the effects of information technology (IT) in education. Sixty-eight experimental studies conducted on the application of IT in the classrooms were integrated and analyzed. Positive effect sizes were found for learning outcomes, including academic achievement, knowledge retention, task performance, self-reported learning, and self-efficacy. Further analysis revealed the primary effects to be significantly moderated by several factors, categorized under learner and course characteristics. These findings have important implications for both research and practice.

scholarly journals The role of cardiac rehabilitation using exercise to decrease natriuretic peptide levels in non-surgical patients: a systematic review

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Christella S. Alphonsus ◽  
Pooveshni Govender ◽  
Reitze N. Rodseth ◽  
Bruce M. Biccard
Keyword(s):  
Natriuretic Peptide ◽  
Exercise Therapy ◽  
Meta Analysis ◽  
Control Group ◽  
Significant Heterogeneity ◽  
Time Period ◽  
Cochrane Database ◽  
Ebsco Host ◽  
And Control

AbstractExercise is recommended in patients with cardiac failure. In the perioperative patient, exercise is also gaining popularity as a form of prehabilitation. In this meta-analysis, we examine if exercise is able to reduce natriuretic peptide levels. Natriuretic peptide (NP) has strong prognostic ability in identifying patients who will develop adverse postoperative cardiovascular outcomes. The protocol was registered with PROSPERO (CRD42017051468). The database search included MEDLINE (PubMed), CINAHL (EBSCO host), EMBASE (EBSCO host), ProQuest, Web of Science, and Cochrane database. The primary outcomes were to determine whether exercise therapy was effective in reducing NP levels as compared to control group, the shortest time period required to reduce NP levels after exercise therapy, and whether reducing NP levels decreased morbidity and mortality. Full texts of 16 trials were retrieved for this review. Exercise therapy showed a significant reduction in natriuretic peptide levels between the intervention and control groups (SMD − 0.45, 95% CI − 0.88 to − 0.03) with significant heterogeneity between the included trials. This was also shown in the within a 12-week period.

Internationalization and family firm performance

2020 ◽  
Vol 27 (1) ◽  
pp. 1-25
Author(s):  
Bart J. Debicki ◽  
Chao Miao ◽  
Shanshan Qian
Keyword(s):  
Firm Performance ◽  
Family Firms ◽  
Meta Analysis ◽  
Family Firm ◽  
Future Research ◽  
Content Type ◽  
Potential Impact ◽  
The Impact ◽  
Positive Effect

Purpose The purpose of this paper is to evaluate the effect of internationalization on performance in family firms, as well as the potential impact of moderators on this relationship. Design/methodology/approach This paper is a meta-analysis of the impact of internationalization on performance in family firms, as well as the role of several moderators shaping this relationship, based on 29 studies. Findings The findings indicate a significant positive effect of internationalization on family firm performance. This relationship was stronger in family firms with lower family ownership. Several methodological moderators were significant, such as the means of measuring performance and internationalization. The results also point to several cultural moderators, such as individualism, masculinity, low uncertainty avoidance and short-term orientation, which positively influence the main effect. Originality/value The authors provide discussions of the results, their practical and theoretical implications, as well as avenues for future research.

Multiple sclerosis and nutrition

2005 ◽  
Vol 11 (1) ◽  
pp. 24-32 ◽  
Author(s):  
Stefan Schwarz ◽  
Hans Leweling
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Unsaturated Fatty Acids ◽  
Early Stage ◽  
Meta Analysis ◽  
Saturated Fat ◽  
Epidemiological Studies ◽  
Linoleic Acid Intake ◽  
Positive Effect

Benefits from any particular diet in multiple sclerosis (MS) have not yet been proven. It is, however, frequent that malnutrition may potentially exacerbate the symptoms of MS. There is some evidence that a high intake of saturated fat increases the incidence of MS. Epidemiological studies imply that unsaturated fatty acids may have a positive effect on the course of MS. However, the results of controlled studies are ambiguous. A meta-analysis of three small controlled clinical trials suggests a benefit from linoleic acid. Intake of Vitamin D is associated with a lower incidence of MS. In MS, the risk of osteoporosis is high, and prophylactic vitamin D and calcium should be considered at an early stage. The role of minerals, trace elements, antioxidants, vitamins or fish oil is unclear. The possible relationships between diet and MS have not been subjected to adequate study. It seems possible that in the future, diets or dietary supplements may become recommended forms of treatment for MS.

Chronic Pain: Fundamental Scientific Considerations, Specifically for Legal Claims

2013 ◽  
Vol 18 (1) ◽  
pp. 1-18 ◽  
Author(s):  
Robert J. Barth
Keyword(s):  
Health Outcomes ◽  
Pain Perception ◽  
Driving Forces ◽  
Psychological Treatment ◽  
Dominant Role ◽  
Meta Analysis ◽  
General Medicine ◽  
Pain Syndrome ◽  
Problematic Relationship

Abstract Scientific findings have indicated that psychological and social factors are the driving forces behind most chronic benign pain presentations, especially in a claim context, and are relevant to at least three of the AMA Guides publications: AMA Guides to Evaluation of Disease and Injury Causation, AMA Guides to Work Ability and Return to Work, and AMA Guides to the Evaluation of Permanent Impairment. The author reviews and summarizes studies that have identified the dominant role of financial, psychological, and other non–general medicine factors in patients who report low back pain. For example, one meta-analysis found that compensation results in an increase in pain perception and a reduction in the ability to benefit from medical and psychological treatment. Other studies have found a correlation between the level of compensation and health outcomes (greater compensation is associated with worse outcomes), and legal systems that discourage compensation for pain produce better health outcomes. One study found that, among persons with carpal tunnel syndrome, claimants had worse outcomes than nonclaimants despite receiving more treatment; another examined the problematic relationship between complex regional pain syndrome (CRPS) and compensation and found that cases of CRPS are dominated by legal claims, a disparity that highlights the dominant role of compensation. Workers’ compensation claimants are almost never evaluated for personality disorders or mental illness. The article concludes with recommendations that evaluators can consider in individual cases.

Potential Uses of Vinegar as a Medicine and Related in vivo Mechanisms

2016 ◽  
Vol 86 (3-4) ◽  
pp. 127-151 ◽  
Author(s):  
Zeshan Ali ◽  
Zhenbin Wang ◽  
Rai Muhammad Amir ◽  
Shoaib Younas ◽  
Asif Wali ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Review Paper ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Active Role ◽  
Current Review ◽  
Different Types ◽  
Positive Effect

While the use of vinegar to fi ght against infections and other crucial conditions dates back to Hippocrates, recent research has found that vinegar consumption has a positive effect on biomarkers for diabetes, cancer, and heart diseases. Different types of vinegar have been used in the world during different time periods. Vinegar is produced by a fermentation process. Foods with a high content of carbohydrates are a good source of vinegar. Review of the results of different studies performed on vinegar components reveals that the daily use of these components has a healthy impact on the physiological and chemical structure of the human body. During the era of Hippocrates, people used vinegar as a medicine to treat wounds, which means that vinegar is one of the ancient foods used as folk medicine. The purpose of the current review paper is to provide a detailed summary of the outcome of previous studies emphasizing the role of vinegar in treatment of different diseases both in acute and chronic conditions, its in vivo mechanism and the active role of different bacteria.

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