scholarly journals Melioidosis in Northeastern State of Malaysia: Spatial Analysis of Cases and Sequence Types

Melioidosis is caused by Burkholderia pseudomallei which can be found in water and soil, as well as in animals. This study was carried out to study the spatial distributions of the cases and their sequence types (ST) from the isolates. The cases were taken from the Hospital USM admission records from the years 2014 to 2019. There were 70 cases which from these cases 33 bacterial isolates were included in this study. Multi-locus Sequence Typing (MLST) was performed to the isolates. As the results, six novel STs were discovered. The cases were found to be clustered and concentrated in the northern part of the state. This study had revealed 15 different STs however, the predominant variant, ST371 (n=6) were found to be distributed in a dispersed manner. Meanwhile, the novel STs were found distributed sporadically in few districts of the state.

2018 ◽  
Vol 147 ◽  
Author(s):  
Y. Fang ◽  
Z. Hu ◽  
H. Chen ◽  
J. Gu ◽  
H. Hu ◽  
...  

AbstractPreviously, we reported a phylogenetic study of 98 Burkholderia pseudomallei clinical isolates from Hainan, China. Here, we update the B. pseudomallei strain library with 52 strains from newly identified cases dating from 2014 to 2017, analysed by multilocus sequence typing. Twenty-two sequence types (STs) were identified from the 52 cases, illustrating high genetic diversity; five of them (ST1480, ST1481, ST1482, ST1483 and ST1484) were novel. ST46, ST50 and ST58 predominated (34.6%) as was the case in the previous study (35.7%). An e-BURST map of the ST profiles of the two collections of isolates showed their genetic foundation to be largely unchanged. Neighbour-joining tree analysis was suggestive of a close phylogenetic relationship between the novel STs from this series and those first reported from Hainan (ST1105, ST1099, ST55 and ST1095). Moreover, the two novel STs (1481 and 1483) showed close similarity to ST58 which originated in Thailand indicating a close relationship between B. pseudomallei strains from both countries. The previously described allele profiles gmhD-36 and lepA-68 were found for the first time in our strain collections. Our study emphasises the importance of monitoring the epidemiological status and evolutionary trends of B. pseudomallei in China.


2013 ◽  
Vol 3 (2) ◽  
pp. 161-183
Author(s):  
Mary L. Mullen

This article considers the politics and aesthetics of the colonial Bildungsroman by reading George Moore's often-overlooked novel A Drama in Muslin (1886). It argues that the colonial Bildungsroman does not simply register difference from the metropolitan novel of development or express tension between the core and periphery, as Jed Esty suggests, but rather can imagine a heterogeneous historical time that does not find its end in the nation-state. A Drama in Muslin combines naturalist and realist modes, and moves between Ireland and England to construct a form of untimely development that emphasises political processes (dissent, negotiation) rather than political forms (the state, the nation). Ultimately, the messy, discordant history represented in the novel shows the political potential of anachronism as it celebrates the untimeliness of everyday life.


2020 ◽  
Vol 1 (1) ◽  
pp. 150-158
Author(s):  
A. V. Zhuchkova

The article deals with A. Bushkovsky’s novel Rymba that goes beyond the topics typical of Russian North prose. Rather than limiting himself to admiring nature and Russian character, the author portrays the northern Russian village of Rymba in the larger context of the country’s mentality, history, mythology, and gender politics. In the novel, myth clashes with reality, history with the present day, and an individual with the state. The critic draws a comparison between the novel and the traditions of village prose and Russian North prose. In particular, Bushkovsky’s Rymba is discussed alongside V. Rasputin’s Farewell to Matyora [ Proshchanie s Matyoroy ] and R. Senchin’s The Flood Zone [ Zona zatopleniya ]. The novel’s central question is: what keeps the Russian world afloat? Depicting the Christian faith as such a bulwark, Bushkovsky links atheism with the social and spiritual roles played by contemporary men and women. The critic argues, however, that the reliance on Christianity in the novel verges on an affectation. The book’s main symbol is a drowning hawk: it perishes despite people’s efforts to save it.


Author(s):  
أميرة عبد الحفيظ عمارة

This research is interested in studying the reality of translation from Hebrew to Arabic, especially the translation of novels. The research relied on translated and published novels, from certain publishing houses, and it includes about 29 novels translated from Hebrew to Arabic. The first translation in this field was Ahavat Zion )loving Zion(, a novel by Abraham Mapu (1808-1867), translated by Salim Al-Dawoodi, and published by the Al-khidewiah Press in Cairo in 1899. Translations from Hebrew to, and vice versa, had Flourished after the establishment of the State of Israel, in particular after 1967 War, and resumed after the peace agreement with Israel. The largest wave of such translations was carried out in newspapers, magazines and academic research in part. The eighties and nineties of the last century were a period of translation activity in regard of partial translations in newspapers. The numbers of translations of full novels published so far have not exceeded thirty in most cases, and the number of translations published in Israel is approximate to the translations published in the Arab countries. The trends of novels that were translated inside Israel were of specific trends, and the translated works that were chosen were initiated, encouraged, and financed by organizations supported by the Israeli establishment. In addition, the translators also had a role in choosing the translated novels into Arabic to obtain financial support. As for the translated Hebrew works in the Arab countries, their focus was on the conditions and sufferings of the Israelis from Arab descent in Israel, and on the failure of Zionism and the issues of existential anxiety the Israelis are experiencing.


Author(s):  
Hawraa Al-Hassan

The book examines the trajectory of the state sponsored novel in Iraq and considers the ways in which explicitly political and/or ideological texts functioned as resistive counter narratives. It argues that both the novel and ‘progressive’ discourses on women were used as markers of Iraq’s cultural revival under the Ba‘th and were a key element in the state’s propaganda campaign within Iraq and abroad. In an effort to expand its readership and increase support for its pan-Arab project, the Iraqi Ba‘th almost completely eradicated illiteracy among women. As Iraq was metaphorically transformed into a ‘female’, through its nationalist trope, women writers simultaneously found opportunities and faced obstacles from the state, as the ‘Woman Question’ became a site of contention between those who would advocate the progressiveness of the Ba‘th and those who would stress its repressiveness and immorality. By exploring discourses on gender in both propaganda and high art fictional writings by Iraqis, this book offers an alternative narrative of the literary and cultural history of Iraq. It ultimately expands the idea of cultural resistance beyond the modern/traditional, progressive/backward paradigms that characterise discourses on Arab women and the state, and argues that resistance is embedded in the material form of texts as much as their content or ideological message.


Author(s):  
Dhyanine Morais de Lima Raimundo ◽  
George Jó Bezerra Sousa ◽  
Ana Beatriz Pereira da Silva ◽  
Romanniny Hévillyn Silva Costa Almino ◽  
Nanete Carolina da Costa Prado ◽  
...  

ABSTRACT Objective: To analyze the spatial distribution of congenital syphilis cases in a state in northeastern Brazil. Method: This is an ecological study, with secondary data for the period from 2008 to 2018, taking as a sample the notified cases of congenital syphilis in Rio Grande do Norte. In the data analysis, the eight health regions of the state were used as units of analysis, and the local and global Moran’s I was performed, with subsequent smoothing through the local empirical Bayesian method, which resulted in thematic maps. Results: The results showed an increase in cases of congenital syphilis in the 3rd and 7thhealth regions. In terms of spatial analysis, this investigation showed clusters in the 3rd, 5th, and 7thhealth regions, with an increased risk for congenital syphilis of up to 2.65 times and with an incidence rate of 7.91 cases per 1,000 live births. Conclusion: The spatial analysis of congenital syphilis cases allowed observing a high incidence in some health regions, with averages above those calculated for the entire state, indicating the need to implement effective strategies to achieve its control.


2021 ◽  
Vol 27 (3) ◽  
pp. 155-160
Author(s):  
Artem D. Morozov

The article deals with the novel ‟Letters from a Peruvian Woman” (Lettres d'une Péruvienne, 1747) by Madame de Graffigny, which anticipates many ideas of Jean-Jacques Rousseau, including the notion of state of nature. The main character, a young Peruvian woman, who was taken away to France, embodies the concept of the ‟noble savage”. Unlike civilised Europeans she has high moral qualities, critically evaluates the institutions and customs of her time, and she aspires to the state of nature, though knowledge about this world did not make her happy. Madame de Graffigny uses the Peruvian theme according to the general interest in the age of Enlightenment in the Inca Empire, which was considered as idyllic society, organised under the laws of nature. She tries, like Jean-Jacques Rousseau, to display merits of savages and demerits of civilised Europeans. The intellectual influence of Madame de Graffigny and Jean-Jacques Rousseau on each other is confirmed by their personal contacts. As a result, we claim that the novel ‟Letters from a Peruvian Woman” was influenced by advanced philosophical ideas of the mid-18thcentury – this text stands at the origins of the concept of the ‟state of nature”, which eventually became one of the main terms of Rousseauism.


2018 ◽  
Vol 12 (11) ◽  
pp. 1039-1044
Author(s):  
Nadjet Aggoune ◽  
Hassiba Tali Maamar ◽  
Farida Assaous ◽  
Badia Guettou ◽  
Rym Laliam ◽  
...  

Introduction: The aim of this study was to investigate the presence of carbapenemase-producing Enterobacteriaceae (CPE) in Algerian hospitals and to characterize the molecular types of carbapenemases found. Methodology: During a four years study lasting between 2012 and 2015, 81 strains of Enterobacteriaceae with reduced susceptibility to carbapenems were collected from different hospitals. Carbapenemase genes were detected by PCR. Multi locus sequence typing was used to study genetic relationships between carbapenemase- producing Klebsiella pneumoniae isolates. Results: Among 56 confirmed CPE, blaOXA-48 was detected in 98.21% of isolates. Two isolates co-expressed NDM, and a single one was only an NDM producer. The strains displayed various susceptibility patterns to antibiotics with variable levels of resistance to carbapenems. Multilocus sequence typing (MLST) revealed the presence of multiple sequence types in circulation. Conclusions: This report highlights the wide distribution of several clones of OXA-48-producing Enterobacteriaceae in Algeria. Urgent action should be taken to avoid epidemic situations.


2014 ◽  
Vol 53 (1) ◽  
pp. 323-326 ◽  
Author(s):  
Birgit De Smet ◽  
Derek S. Sarovich ◽  
Erin P. Price ◽  
Mark Mayo ◽  
Vanessa Theobald ◽  
...  

Burkholderia pseudomalleiisolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy.


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