Quando la febbre non ha una chiara localizzazione: pensa anche alla nefrite focale acuta

2021 ◽  
Vol 40 (3) ◽  
pp. 186-188
Author(s):  
Alice Falcioni ◽  
Angela Troisi ◽  
Luca Casadio ◽  
Antonio Chiaravalloti ◽  
Maria Teresa Minguzzi ◽  
...  

Acute lobar nephronia, Diagnosis, Magnetic resonance imaging, Case report Acute lobar nephronia (ALN) is a non-suppurative focal form of acute bacterial infection, generally affecting one or more renal lobules. In the spectrum of upper urinary tract infection ALN is consid-ered a midpoint between uncomplicated pyelonephritis and intrarenal abscess. This condition may be difficult to recognize due to the lack of specific symptoms and laboratory findings. The reported incidence of ALN has increased as a result of advancements in non-invasive imaging techniques such as renal ultrasonography. Computed tomography scanning is the diagnostic gold standard for ALN, but magnetic resonance imagining (MRI) should be considered to limit irradiation and be-cause of its high sensitivity in detecting inflammatory changes in the renal parenchyma. The diag-nosis is relevant since initial intravenous antibiotic therapy and overall length of treatment, usually 3 weeks, are longer respect to those for uncomplicated acute pyelonephritis. The present paper de-scribes the case of a 4-year-old girl with septic fever, sick appearance, elevation of inflammatory indexes with negative blood and urine cultures and non-specific abdominal ultrasonography in which a detailed evaluation of MRI led to the diagnosis of acute lobar nephronia. La nefrite focale acuta (NFA) è una forma focale non suppurativa di infezione batterica acuta, che generalmente colpisce uno o più lobuli renali. Nello spettro delle infezioni delle vie urinarie superiori, l'NFA è considerata un punto medio tra la pielonefrite non complicata e l'ascesso intrarenale. Questa condizione può essere difficile da riconoscere a causa della mancanza di sintomi specifici e risultati di laboratorio. L'incidenza riportata di NFA è aumentata a seguito dei progressi nelle tecniche di imaging non invasive come l'ecografia renale. La tomografia computerizzata è il gold standard diagnostico per l'NFA, ma la risonanza magnetica per immagini (MRI) dovrebbe essere considerata per limitare l'irradiazione e per la sua elevata sensibilità nel rilevare i cambiamenti infiammatori nel parenchima renale. La diagnosi è rilevante poiché la terapia antibiotica per via endovenosa iniziale e la durata complessiva del trattamento, di solito 3 settimane, sono più lunghe rispetto a quelle per la pielonefrite acuta non complicata. Il presente articolo descrive il caso di una bambina di 4 anni con febbre settica, aspetto malato, aumento degli indici infiammatori con emocolture e urine negative ed ecografia addominale aspecifica in cui una valutazione dettagliata della risonanza magnetica ha portato alla diagnosi di nefronia lobare acuta.

2007 ◽  
Vol 122 (6) ◽  
pp. 639-640 ◽  
Author(s):  
D Mcintosh ◽  
M Mahadevan

AbstractIntroduction:Acute sinusitis is a relatively common condition, which usually responds to medical therapy. In most cases, there are no sequelae or complications subsequent to this infection. However, like many acute illnesses, there are well documented complications of acute sinusitis, and in particular these include peri-orbital and intracranial spread.Objective:The purpose of this paper is to highlight the importance of vigilance in peri-orbital involvement and the limitations of imaging techniques, such as computed tomography scanning. An illustrative case is presented to demonstrate this.Conclusion:Magnetic resonance imaging scanning is a valuable modality in assessing complex presentations of peri-orbital complications of acute sinusitis.


1997 ◽  
Vol 10 (2_suppl) ◽  
pp. 28-30 ◽  
Author(s):  
M. Mortilla ◽  
M. Ermini ◽  
M. Nistri ◽  
G. Dal Pozzo ◽  
F. Falcini

Systemic lupus erythematosus can produce disturbances in the CNS, characterized by seizures, headache, encephalopathy, chorea, cerebral infarction and psychosis. We used magnetic resonance and spectroscopy, in order to provide anatomical and metabolic information on the direct involvement of the CNS in LES. This study shows how these non-invasive techniques are well tolerated by children and young adults and how the levels of N-acetylaspartate correlate with the severity of the disease.


2020 ◽  
Vol 37 (1) ◽  
Author(s):  
Sohbia Munir ◽  
Sohail Ahmed Khan ◽  
Hina Hanif ◽  
Maria Khan

Objective: To evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) in detection of intra-axial gliomas in suspected cases keeping histopathology as gold standard. Methods: This cross-sectional study was conducted at Dow Institute of Radiology, DUHS from October 2017 - April 2018. Patients of either gender aged 30-70 years presenting with headache were included. Patients already diagnosed and referred for follow up were excluded. MRI was performed on 1.5T scanner by a trained MRI technician. T1, T2, FLAIR, diffusion weighted and T1 post contrast images were acquired and reviewed by two radiologists having more than five years post fellowship experience. Sensitivity, specificity, PPV, NPV and diagnostic accuracy of MRI for intraaxial gliomas was calculated taking histopathology findings as gold standard. Results: Mean age of the patient`s was 51.71 ±10.85 years. Positive intraaxial gliomas on MRI were observed in 123 (79.90%) patients while on histopathology, positive intraaxial gliomas were observed in 131 (85.10%) patients. Diagnostic accuracy of MRI in detection of intra-axial gliomas taking histopathology findings as gold standard showed sensitivity, specificity, positive predicted value (PPV), negative predicted value (NPV) and overall diagnostic accuracy as 89.31%, 73.91%, 95.12%, 54.84% and 87.01%. Conclusions: MRI has high sensitivity, moderate specificity and high diagnostic accuracy in detection of intraaxial gliomas. doi: https://doi.org/10.12669/pjms.37.1.2489 How to cite this:Munir S, Khan SA, Hanif H, Khan M. Diagnostic accuracy of magnetic resonance imaging in detection of intra-axial gliomas. Pak J Med Sci. 2021;37(1):125-130. doi: https://doi.org/10.12669/pjms.37.1.2489 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2012 ◽  
Vol 1374 ◽  
pp. 17-25
Author(s):  
Jocelyn Alcántara García ◽  
José Luis Ruvalcaba Sil ◽  
Marie Van der Meeren

ABSTRACTThe necessity of studying cultural heritage through non-invasive and non-destructive techniques has led to significant advances in the last decade. One of the most recent advancements in this theme in Mexico is the portable X-ray system SANDRA, which was used to study three manuscripts directly related to the history of “San Nicolás Coatepec”, Mexico. X-ray fluorescence was chosen as the suitable technique because it can provide a fast qualitative and quantitative multielemental high sensitivity analysis. The documents were examined globally, using imaging techniques with UV and IR lighting. This research evinced a change in the composition and evolution of writing materials (inks and pigments) and provided information concerning historical use of the documents and its actual legal value as a property document. It also stressed the need of spanning these results to an extensive research attaining other regions of Mexico, in order to fully understand the Mexican documents particularities, aging and deterioration. This, in turn, will provide not only historical material information but also an invaluable scoop to understand deterioration and conservation issues.


Author(s):  
Mudasir Ahmad Shah ◽  
Abas Rashid Bhat ◽  
Mohammed Arif Basha ◽  
Abhishek Saxena

Urolithiasis poses an acute life threatening emergency and most frequently obstructs the lower urinary tract in male dogs (Franti et al., 1999). It has been reported that the upper urinary tract calculi are uncommon in dogs and cats with majority of uroliths (Osborne and Fletcher, 1995). The most probable causes include infections, nutritional deficiencies and mineral imbalances. The mineral deposits which form in the bladder of male dogs get flushed out of the bladder with urine and lodge in the penis just behind the os penis which is the most commonly reported site of obstruction followed by ischial arch (Franti et al., 1999). Diagnostic imaging techniques like radiography and ultrasonography are sensitive in diagnosis, with abdominal ultrasonography having 90% sensitivity, 98% specificity and 97% accuracy (Webb, 2000). Treatment of urolithiasis can be attempted by retrograde urethral hydropropulsion for urethroliths followed by cystotomy (Osborne et al., 1999), failing of which urethrotomy or urethrostomy is indicated (Smeak, 2000). Other techniques like bladder marsupialization, surgical tube cystostomy and minimal invasive surgical tube cystostomy with their short and long-term complications have been attempted. However, in this study the cases were relieved by retrograde urethral hydropropulsion, cystotomy and urethrotomy.


Author(s):  
Grigorios Chatzantonis ◽  
Michael Bietenbeck ◽  
Ahmed Elsanhoury ◽  
Carsten Tschöpe ◽  
Burkert Pieske ◽  
...  

Abstract Background Cardiac amyloidosis (CA) is an infiltrative disease characterised by accumulation of amyloid deposits in the extracellular space of the myocardium—comprising transthyretin (ATTR) and light chain (AL) amyloidosis as the most frequent subtypes. Histopathological proof of amyloid deposits by endomyocardial biopsy (EMB) is the gold standard for diagnosis of CA. Cardiovascular magnetic resonance (CMR) allows non-invasive workup of suspected CA. We conducted a multi-centre study to assess the diagnostic value of CMR in comparison to EMB for the diagnosis of CA. Methods We studied N = 160 patients characterised by symptoms of heart failure and presence of left ventricular (LV) hypertrophy of unknown origin who presented to specialised cardiomyopathy centres in Germany and underwent further diagnostic workup by both CMR and EMB. If CA was diagnosed, additional subtyping based on EMB specimens and monoclonal protein studies in serum was performed. The CMR protocol comprised cine- and late-gadolinium-enhancement (LGE)-imaging as well as native and post-contrast T1-mapping (in a subgroup)—allowing to measure extracellular volume fraction (ECV) of the myocardium. Results An EMB-based diagnosis of CA was made in N = 120 patients (CA group) whereas N = 40 patients demonstrated other diagnoses (CONTROL group). In the CA group, N = 114 (95%) patients showed a characteristic pattern of LGE indicative of CA. In the CONTROL group, only 1/40 (2%) patient showed a “false-positive” LGE pattern suggestive of CA. In the CA group, there was no patient with elevated T1-/ECV-values without a characteristic pattern of LGE indicative of CA. LGE-CMR showed a sensitivity of 95% and a specificity of 98% for the diagnosis of CA. The combination of a characteristic LGE pattern indicating CA with unremarkable monoclonal protein studies resulted in the diagnosis of ATTR-CA (confirmed by EMB) with a specificity of 98% [95%-confidence interval (CI) 92–100%] and a positive predictive value (PPV) of 99% (95%-CI 92–100%), respectively. The EMB-associated risk of complications was 3.13% in this study—without any detrimental or persistent complications. Conclusion Non-invasive CMR shows an excellent diagnostic accuracy and yield regarding CA. When combined with monoclonal protein studies, CMR can differentiate ATTR from AL with high accuracy and predictive value. However, invasive EMB remains a safe invasive gold-standard and allows to differentiate CA from other cardiomyopathies that can also cause LV hypertrophy.


Author(s):  
MA Omer ◽  
SS Malik ◽  
MN Anjum ◽  
Az Riaz ◽  
R Ali

Meniscal tears are mostly seen worldwide. Multiple imaging modalities are currently used to evaluate pathologic conditions of the knee. MRI can be referred as the non-invasive gold standard investigation to help establishing diagnosis of meniscal tears, but it economically unaffordable to most of patients and needs long examination times. Ultrasound is a possible alternative to MRI. It is simple, convenient and an inexpensive and non-invasive method. The use of ultrasound in identifying meniscal tears has been proposed, but its diagnostic accuracy remains controversial. The objective of the research is to define the diagnostic accurateness of ultrasound scan in detecting meniscal tears taking magnetic resonance imaging as gold standard. It was a diagnostic cross-sectional study in which 78 patients visiting Department of Diagnostic Radiology, Doctors Hospital, Lahore were included. Convenient sampling technique was used. Written informed consent was taken from all the patients. Patients were investigated with the help of ultrasound and results were noted on the designed proforma, subsequently the results were compared to the MRI scan of the knee joint. Data was entered and statistically analyzed using SPSS 21.0. Frequency tables were generated for all variables. For quantitative data like age mean and standard deviation were calculated and for qualitative data like sex and meniscal tears percentages were calculated. Sensitivity, Specificity, Positive Predictive Value, Negative Predictive Value was given. Bar and pie charts were used to present categorical data. Kappa analysis was utilized. The mean age of the patients was 38.18+12.818 years, 82.1% were males and 47.4% had sports trauma. Out of 48 medial meniscus tear on USG, 38(48.7%) were true positive and 10(12.8%) were false positive on MRI. Out of 10 lateral meniscus tear on USG, 9(11.5%) were true positive and 1(1.3%) was false positive on MRI. The sensitivity, specificity, PPV, NPV and diagnostic accuracy of ultrasound for medial meniscus tears were 95.00%, 73.68%, 79.16%, 93.33% and 84.61% while for lateral meniscus tears were 75.00%, 98.48%, 90.00%, 95.58% and 94.87%, respectively. Study concluded that ultrasound has good diagnostic accuracy when compared with magnetic resonance imaging in detecting meniscal tears.


2011 ◽  
Vol 140 ◽  
pp. 178-182
Author(s):  
Guang Qian Ji ◽  
Jun Wei ◽  
Yu Tian

With the development of modern medical imaging technology, computer tomography (CT), magnetic resonance imaging (MRI), magnetic resonance angiography (MRA), digital subtraction angiography (DSA) and other ways widely used, more and more intracranial aneurysms were diagnosed. In the imaging methods described above, MRI is a non-invasive diagnostic method for intracranial aneurysm which shows in detail the aneurysm and its relationship to the brain, and it has become first-line imaging techniques in assessment of the patient with suspected intracranial aneurysm. MRA can show the arteries and veins of the brain as well as the aneurysm. Nowadays, MRI and MRA are extensively used in the diagnosis of intracranial aneurysms, intracranial aneurysms after treatment and intracranial aneurysms inflammation. This review describes the advantages of MRI and MRA for diagnosis and describes diagnostic pitfalls.


2018 ◽  
Vol 5 (2) ◽  
pp. 34-40
Author(s):  
David Ailton Dias Filho ◽  
Paulo Martins Reis Júnior ◽  
Wellington Andraus

ABSTRACT Introduction: Recent studies suggest that hepatic steatosis is a worldwide distribution pathology that can progress to chronic liver disease with a highly unfavorable outcome resulting in the need for liver transplantation. That’s why early diagnosis is important. The liver biopsy’s considered a "gold standard" in its diagnosis, but the use of ultrasonography helps to detect steatosis in a non-invasive manner and is a very accessible method for the population. Objectives: To evaluate the frequency of steatosis in patients treated at a radiological clinic in Palmas using abdominal ultrasonography; observing its distribution in genders and age groups and its difference between 2010 and 2016. Methods: It was used ultrasound reports of abdomen of 3.222 patients made in 2010 and of 2.346 patients made in 2016. A longitudinal analysis was performed, between these two years, regarding the frequency of hepatic steatosis at the people and also between the genders and the age groups. Results: In 2010, 25,67% of people had hepatic steatosis in the ultrasound report, while in 2016 were 31,67%. In 2010, of the total number of people with steatosis, 52,48% were women and 47,52% were men; however in 2016, 51,94% were women and 48,06% were men. Regarding the age groups, in both periods, as in men and in women, steatosis was lower at the extremes of age and more frequent around the 5th to 7th decades of life. Discussion: The frequency of hepatic steatosis has increased in the period from 2010 to 2016. It was, as seen in the literature, quite high in the 5th and 6th decades of life, besides being more frequent in females. Unlike 2010, in 2016 begins to have children under 20 with signs of steatosis. Conclusion: In the year 2010 the frequency of hepatic steatosis was 25,67%, whereas in 2016 it was 31,84%.   Keywords: Steatosis; ultrasonography; liver.


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