FREQUENCY OF HEPATIC STEATOSIS IN A RADIOLOGY CLINIC IN PALMAS

2018 ◽  
Vol 5 (2) ◽  
pp. 34-40
Author(s):  
David Ailton Dias Filho ◽  
Paulo Martins Reis Júnior ◽  
Wellington Andraus
Keyword(s):  
Liver Transplantation ◽  
Hepatic Steatosis ◽  
Gold Standard ◽  
Age Groups ◽  
Abdominal Ultrasonography ◽  
Non Invasive ◽  
Worldwide Distribution ◽  
The People ◽  
Accessible Method ◽  
Made In

ABSTRACT Introduction: Recent studies suggest that hepatic steatosis is a worldwide distribution pathology that can progress to chronic liver disease with a highly unfavorable outcome resulting in the need for liver transplantation. That’s why early diagnosis is important. The liver biopsy’s considered a "gold standard" in its diagnosis, but the use of ultrasonography helps to detect steatosis in a non-invasive manner and is a very accessible method for the population. Objectives: To evaluate the frequency of steatosis in patients treated at a radiological clinic in Palmas using abdominal ultrasonography; observing its distribution in genders and age groups and its difference between 2010 and 2016. Methods: It was used ultrasound reports of abdomen of 3.222 patients made in 2010 and of 2.346 patients made in 2016. A longitudinal analysis was performed, between these two years, regarding the frequency of hepatic steatosis at the people and also between the genders and the age groups. Results: In 2010, 25,67% of people had hepatic steatosis in the ultrasound report, while in 2016 were 31,67%. In 2010, of the total number of people with steatosis, 52,48% were women and 47,52% were men; however in 2016, 51,94% were women and 48,06% were men. Regarding the age groups, in both periods, as in men and in women, steatosis was lower at the extremes of age and more frequent around the 5th to 7th decades of life. Discussion: The frequency of hepatic steatosis has increased in the period from 2010 to 2016. It was, as seen in the literature, quite high in the 5th and 6th decades of life, besides being more frequent in females. Unlike 2010, in 2016 begins to have children under 20 with signs of steatosis. Conclusion: In the year 2010 the frequency of hepatic steatosis was 25,67%, whereas in 2016 it was 31,84%.   Keywords: Steatosis; ultrasonography; liver.

Quando la febbre non ha una chiara localizzazione: pensa anche alla nefrite focale acuta

2021 ◽  
Vol 40 (3) ◽  
pp. 186-188
Author(s):  
Alice Falcioni ◽  
Angela Troisi ◽  
Luca Casadio ◽  
Antonio Chiaravalloti ◽  
Maria Teresa Minguzzi ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Gold Standard ◽  
Imaging Techniques ◽  
Risonanza Magnetica ◽  
High Sensitivity ◽  
Upper Urinary Tract ◽  
Abdominal Ultrasonography ◽  
Laboratory Findings ◽  
Non Invasive ◽  
Computed Tomography Scanning

Acute lobar nephronia, Diagnosis, Magnetic resonance imaging, Case report Acute lobar nephronia (ALN) is a non-suppurative focal form of acute bacterial infection, generally affecting one or more renal lobules. In the spectrum of upper urinary tract infection ALN is consid-ered a midpoint between uncomplicated pyelonephritis and intrarenal abscess. This condition may be difficult to recognize due to the lack of specific symptoms and laboratory findings. The reported incidence of ALN has increased as a result of advancements in non-invasive imaging techniques such as renal ultrasonography. Computed tomography scanning is the diagnostic gold standard for ALN, but magnetic resonance imagining (MRI) should be considered to limit irradiation and be-cause of its high sensitivity in detecting inflammatory changes in the renal parenchyma. The diag-nosis is relevant since initial intravenous antibiotic therapy and overall length of treatment, usually 3 weeks, are longer respect to those for uncomplicated acute pyelonephritis. The present paper de-scribes the case of a 4-year-old girl with septic fever, sick appearance, elevation of inflammatory indexes with negative blood and urine cultures and non-specific abdominal ultrasonography in which a detailed evaluation of MRI led to the diagnosis of acute lobar nephronia. La nefrite focale acuta (NFA) è una forma focale non suppurativa di infezione batterica acuta, che generalmente colpisce uno o più lobuli renali. Nello spettro delle infezioni delle vie urinarie superiori, l'NFA è considerata un punto medio tra la pielonefrite non complicata e l'ascesso intrarenale. Questa condizione può essere difficile da riconoscere a causa della mancanza di sintomi specifici e risultati di laboratorio. L'incidenza riportata di NFA è aumentata a seguito dei progressi nelle tecniche di imaging non invasive come l'ecografia renale. La tomografia computerizzata è il gold standard diagnostico per l'NFA, ma la risonanza magnetica per immagini (MRI) dovrebbe essere considerata per limitare l'irradiazione e per la sua elevata sensibilità nel rilevare i cambiamenti infiammatori nel parenchima renale. La diagnosi è rilevante poiché la terapia antibiotica per via endovenosa iniziale e la durata complessiva del trattamento, di solito 3 settimane, sono più lunghe rispetto a quelle per la pielonefrite acuta non complicata. Il presente articolo descrive il caso di una bambina di 4 anni con febbre settica, aspetto malato, aumento degli indici infiammatori con emocolture e urine negative ed ecografia addominale aspecifica in cui una valutazione dettagliata della risonanza magnetica ha portato alla diagnosi di nefronia lobare acuta.

scholarly journals Mini Review: Impedance Measurement in Neuroscience and Its Prospective Application in the Field of Surgical Neurooncology

2022 ◽  
Vol 12 ◽  
Author(s):  
Tammam Abboud ◽  
Dorothee Mielke ◽  
Veit Rohde
Keyword(s):  
Clinical Practice ◽  
Human Tissue ◽  
Gold Standard ◽  
Ex Vivo ◽  
Impedance Measurement ◽  
Non Invasive ◽  
Prospective Application ◽  
No Gold Standard ◽  
Made In

Impedance measurement of human tissue can be performed either in vivo or ex vivo. The majority of the in-vivo approaches are non-invasive, and few are invasive. To date, there is no gold standard for impedance measurement of intracranial tissue. In addition, most of the techniques addressing this topic are still experimental and have not found their way into clinical practice. This review covers available impedance measurement approaches in the neuroscience in general and specifically addresses recent advances made in the application of impedance measurement in the field of surgical neurooncology. It will provide an understandable picture on impedance measurement and give an overview of limitations that currently hinders clinical application and require future technical and conceptual solutions.

Applanation Tonometry for Assessment of Left Ventricular Systolic Load

2019 ◽  
Vol 12 (2) ◽  
pp. 94-99
Author(s):  
Rene D. Mileva-Popova ◽  
Nina Y. Belova
Keyword(s):  
Arterial Stiffness ◽  
Augmentation Index ◽  
Age Groups ◽  
Systolic Pressure ◽  
Left Ventricular ◽  
Applanation Tonometry ◽  
Non Invasive ◽  
Pressure Area ◽  
Older Subjects ◽  
And Gender

Summary Vascular-ventricular coupling is a major determinant of left ventricular load. The aim of our study was to assess non- invasively left ventricular load and its dependency on central hemodynamics. Sixty-five healthy and gender-matched individuals were divided in two groups according to their age: 20y/o and 50y/o. Applanation tonometry was performed using the Sphygmocor device. Central pressures and pulse wave analysis indices were computed. Central systolic (120±3 vs. 98±2 mm Hg) and pulse pressures (43±3 vs. 29±1 mm Hg) as well as the augmentation index (AIx75) (23±3 vs. 6±2%) were significantly higher in the 50y/o group (p<0.01). These parameters are relevant markers of arterial stiffness and evidenced the development of central arterial morphological and functional alterations in the older subjects. The time-tension index (TTI) computed from the systolic pressure area was significantly higher in the 50y/o subjects as compared to the 20y/o group (2378±66 vs. 1954±73 mmHg×s, p<0.01). Moreover, we have shown the presence of significant correlation between TTI and AIx75 (p<0.01) in both age groups. This finding confirmed the contribution of arterial stiffness for the impaired vascular-ventricular coupling. In conclusion, applanation tonometry might be utilized for non-invasive evaluation of the left ventricular load, which is an important parameter of cardiovascular risk.

Need of Human Rights as a Better Way of Life

Think India ◽  
2019 ◽  
Vol 22 (3) ◽  
pp. 72-83
Author(s):  
Tushar Kadian
Keyword(s):  
Human Rights ◽  
Basic Needs ◽  
Research Paper ◽  
Human Being ◽  
Way Of Life ◽  
Labour Unions ◽  
The People ◽  
The Subject ◽  
Definition Of ◽  
Made In

Actually, basic needs postulates securing of the elementary conditions of existence to every human being. Despite of the practical and theoretical importance of the subject the greatest irony is non- availability of any universal preliminary definition of the concept of basic needs. Moreover, this becomes the reason for unpredictability of various political programmes aiming at providing basic needs to the people. The shift is necessary for development of this or any other conception. No labour reforms could be made in history till labours were treated as objects. Its only after they were started being treating as subjects, labour unions were allowed to represent themselves in strategy formulations that labour reforms could become a reality. The present research paper highlights the basic needs of Human Rights in life.

Study of functional state of microcirculatory channel system in periodontal tissues in persons of different age groups

2020 ◽  
Vol 20 (2) ◽  
pp. 88-94
Author(s):  
L. Yu. Orekhova ◽  
A. A. Petrov ◽  
E. S. Loboda ◽  
I. V. Berezkina ◽  
K. V. Shadrina
Keyword(s):  
Functional State ◽  
Age Groups ◽  
Peripheral Resistance ◽  
Circulatory System ◽  
Structural Features ◽  
Periodontal Tissues ◽  
Non Invasive ◽  
Age Related ◽  
Group 12 ◽  
Therapeutic Measures

Relevance. The study of age-related features of microcirculation in periodontal tissues, using non-invasive functional research methods, allows us to develop the optimal range of therapeutic measures, as well as form a “personalized therapeutic case”.Purpose. Study of the functional state of the microvasculature in the tissues of the parodont in individuals of various age groups.Materials and methods. A standard dental examination of 80 patients was carried out, the sample of participants was ranked in 4 groups by age: 1 group – 12 years old, 2 group – 15 years old, 3 group – from 16 to 18 years old, 4 group – from 22 to 24 years old. Hygiene and periodontal indices were determined for all patients, such as papillarymarginal-alveolar (PMA) in the Parma modification, the Mulleman bleeding index in the Cowell modification (SBI), and the simplified Green Vermillion index of oral hygiene (OHI–s), caries intensity indicators for a permanent bite (CPI), as well as ultrasound dopplerography of periodontal tissues using the apparatus "Minimax-Doppler-K".Results. When studying microcirculation in periodontal tissues, distinctive characteristics of linear (Vas) and volumetric (Qas) blood flow rates, as well as indicators of pulsation indices (PI) and peripheral resistance (RI) in people of different age groups were recorded.Conclusions. This study confirms the presence of various hemodynamic indicators of periodontal tissues in the studied groups, which is due to structural features of the circulatory system in age periods.

Diagnostic efficacy and suitability of trans-thoracic ultrasonography for pleural fluid detection – The future non-invasive gold-standard?

2020 ◽  
Vol 13 (4) ◽  
pp. 184-190
Author(s):  
Muhammad Irfan ◽  
Abdul Rasheed Qureshi ◽  
Zeeshan Ashraf ◽  
Muhammad Amjad Ramzan ◽  
Tehmina Naeem ◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Diagnostic Accuracy ◽  
Pleural Fluid ◽  
Gold Standard ◽  
Pleural Effusions ◽  
Diagnostic Efficacy ◽  
Chest Sonography ◽  
X Ray ◽  
Non Invasive ◽  
Fluid Detection

ABSTRACT Background: Conventionally Pleural effusions are suspected by history of pleuritis, evaluated by physical signs and multiple view radiography. Trans-thoracic pleural aspiration is done and aspirated pleural fluid is considered the gold-standard for pleural effusion. Chest sonography has the advantage of having high diagnostic efficacy over radiography for the detection of pleural effusion. Furthermore, ultrasonography is free from radiation hazards, inexpensive, readily available  and feasible for use in ICU, pregnant and pediatric patients. This study aims to explore the diagnostic accuracy of trans-thoracic ultrasonography for pleural fluid detection, which is free of such disadvantages. The objective is to determine the diagnostic efficacy of trans-thoracic ultrasound for detecting pleural effusion and also to assess its suitability for being a non-invasive gold-standard.   Subject and Methods: This retrospective study of 4597 cases was conducted at pulmonology  OPD-Gulab Devi Teaching Hospital, Lahore from November 2016 to July 2018. Adult patients with clinical features suggesting pleural effusions were included while those where no suspicion of pleural effusion, patients < 14 years and pregnant ladies were excluded. Patients were subjected to chest x-ray PA and Lateral views and chest ultrasonography was done by a senior qualified radiologist in OPD. Ultrasound-guided pleural aspiration was done in OPD & fluid was sent for analysis. At least 10ml aspirated fluid was considered as diagnostic for pleural effusion. Patient files containing history, physical examination, x-ray reports, ultrasound reports, pleural aspiration notes and informed consent were retrieved, reviewed and findings were recorded in the preformed proforma. Results were tabulated and conclusion was drawn by statistical analysis. Results: Out of 4597 cases, 4498 pleural effusion were manifested on CXR and only 2547(56.62%) pleural effusions were proved by ultrasound while 2050 (45.57%) cases were reported as no Pleural effusion. Chest sonography demonstrated sensitivity, specificity, PPV, NPV and diagnostic accuracy 100 % each. Conclusions: Trans-thoracic ultrasonography revealed an excellent efficacy that is why it can be considered as non-invasive gold standard for the detection of pleural effusion.

Introduction

2017 ◽  
Author(s):  
Jim Tomlinson
Keyword(s):  
Public Opinion ◽  
National Economy ◽  
Gold Standard ◽  
Turning Point ◽  
Economic Management ◽  
The People ◽  
Economic Statistics ◽  
National Economic ◽  
Governmental Management

This introduction outlines how the idea of a national economy subject to governmental management was constructed in Britain out of the dissolution of the unmanaged economy of the pre-1914 era. It argues that a key turning point came in 1931 with the departure from the gold standard and the introduction of protection. But, it is argued, it was only from the 1940s that national economic management was combined with ‘managing the people’, through major efforts to shape public opinion on the economy. This chapter also summarizes the development of the major kinds of economic statistics which underpinned both facets of economic management.

CEUS detection of biliary ischaemia during the first 4 weeks after liver transplantation predicts non-anastomotic biliary stricture

2021 ◽  
pp. 1-12
Author(s):  
Bo-wen Zheng ◽  
Shu-hong Yi ◽  
Tao Wu ◽  
Mei Liao ◽  
Ying-cai Zhang ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Predictive Value ◽  
Biliary Stricture ◽  
Characteristic Curve ◽  
Validation Group ◽  
Gamma Glutamyl Transpeptidase ◽  
Full Cohort ◽  
Non Invasive ◽  
Invasive Method ◽  
Nas Score

BACKGROUND: Biliary ischaemia is an important factor in the pathogenesis of non-anastomotic biliary stricture (NAS) after liver transplantation (LT). Contrast-enhanced ultrasound (CEUS) can be used to detect biliary ischaemia, but no study has examined the utility of CEUS in predicting NAS. OBJECTIVE: To evaluate whether repeated CEUS as a non-invasive method of biliary ischaemia can identify NAS. METHODS: Consecutive LT patients who underwent CEUS examinations at 1–4 weeks after LT from September 2012 to December 2015 at our institution were included. The CEUS images and clinical data were analysed. RESULTS: Among 116 eligible LT patients, 39 (33.6%) were diagnosed with NAS within 1 year after LT. The patients with NAS had a significantly higher CEUS score at weeks 2–4 (all P <  0.05) and a higher slope of CEUS score progression (0.480 vs –0.044, P <  0.001). The accuracy of CEUS in identifying NAS improved over time after LT, reaching its maximum at week 4, with a sensitivity of 66.7%, a specificity of 87.9%, a positive predictive value (PPV) of 75.9%, a negative predictive value (NPV) of 82.3%, and an accuracy of 80.2%in the full cohort when a CEUS score≥3 was used as the cut-off. Multivariate analysis identified gamma-glutamyl transpeptidase (GGT), alanine transaminase (ALT) and the CEUS score at week 4 as independent predictors of NAS. In the task of identifying NAS, an NAS score combining the above 3 variables at week 4 showed areas under the receiver operating characteristic curve of 0.88 (95%CI, 0.78–0.99) in the estimation group (n = 60) and 0.82 (95%CI, 0.69–0.96) in the validation group (n = 56). An NAS score cut-off of 0.396 identified 87.2%of NAS cases in the estimation group, with a PPV of 93.3%; and 75.0%of NAS cases in the validation group, with a PPV of 58.8%. CONCLUSIONS: CEUS examination during the first 4 weeks is useful in assessing the risk of NAS within 1 year after LT. In particular, an NAS score combining the CEUS score, GGT level, and ALT level at week 4 can be used to accurately predict the risk of NAS in LT patients.

scholarly journals Buccal swabs as non-invasive specimens for detection of severe acute respiratory syndrome coronavirus-2

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110169
Author(s):  
Ritu Gaur ◽  
Dipesh Kumar Verma ◽  
Ritin Mohindra ◽  
Kapil Goyal ◽  
Shipra Gupta ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Internal Control ◽  
Gold Standard ◽  
Detection System ◽  
Buccal Swab ◽  
Non Invasive ◽  
Human Rnase ◽  
Buccal Swabs ◽  
Reverse Transcription Quantitative Pcr ◽  
Env Protein

Introduction The current gold standard for detection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) RNA involves subjecting nasopharyngeal or oropharyngeal swabs to reverse transcription quantitative PCR (RT-qPCR). However, both sample types need to be collected by trained professionals. Using self-collected buccal swabs as an alternative could simplify and accelerate diagnosis of coronavirus disease 2019 (COVID-19). Objective To assess self-collected buccal swab samples as an alternative method for SARS-CoV-2 detection in patients with COVID-19. Methods Buccal swab samples were self-collected by 73 patients with COVID-19. Total RNA was extracted using Qiagen kits. RNA encoding the SARS-CoV-2 Env protein and human RNase P as an internal control was amplified using the TRUPCR® SARS-CoV-2 RT-qPCR kit version 2.1 and a Bio-Rad CFX96 Real-Time Detection System. Result The sensitivity of RT-qPCR from buccal swabs was 58.9% (43/73; 95% confidence interval [CI] 46.77%–70.27%) and that of RT-qPCR from saliva was 62.90% (39/62; 95% CI 49.69%–74.84%) taking positive SARS-CoV-2 RT-qPCR from nasopharyngeal swabs as the gold standard. Conclusion Self-collected buccal swabs are promising alternatives to nasopharyngeal or oropharyngeal swabs for SARS CoV-2 detection.

Sign in / Sign up

Export Citation Format

Share Document